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PENGARUH KEPATUHAN DAN POLA PENGOBATAN TERHADAP HASIL TERAPI PASIEN HIPERTENSI Nurul Chusna; Ika Puspitasari; Probosuseno Probosuseno
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 4, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.292

Peningkatan kepatuhan dan pola pengobatan diharapkan dapat mempengaruhi keberhasilan terapi berupa penurunan tekanan darah pasien hipertensi. Penelitian dilakukan untuk mengetahui pengaruh kepatuhan dan pola pengobatan terhadap hasil terapi pasien hipertensi. Penelitian dilakukan dengan metode observasi retrospektif. Pengambilan data pasien secara prospektif dilakukan selama bulan November sampai Desember 2013 di RSUD dr. Doris Sylvanus Palangkarya. Dengan mengambil data dari rekam medik pasien hipertensi dari rawat jalan poliklinik penyakit dalam yang akan digunakan sebagai sampel penelitian. Kepatuhan pasien diukur dengan menggunakan kuesioner MMAS. Selain melakukan penilaian terhadap kepatuhan peneliti juga menilai pola pengobatan pada pasien tersebut. Pola pengobatan diperoleh dari pencatatan rekam medik pasien. Pola pengobatan dibagi menjadi 2 yaitu tunggal dan kombiunasi. Diperoleh 114 subyek penelitian. Terdapat perbedaan bermakna pada kategori MMAS terhadap penurunan tekanan darah sitolik, dan tekanan darah diastolik. Terdapat perbedaan bermakna pada kategori Pola pengobatan terhadap penurunan tekanan darah sistolik, dan tekanan darah diastolik. Kepatuhan dan pola pengobatan dapat berpengaruh bermakna secara statistika terhadap penurunan tekanan darah sistolik dan diastolik pasien. Kata kunci: kepatuhan, pola pengobatan, hasil terapi, hipertensi

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETIL ASETAT DAUN RAMBUSA DAN DAUN KARAMUNTING TERHADAP Streptococcus mutans Muhammad Priyadi; Nurul Chusna; Guntur Satrio Pratomo
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.875

Empirically, many natural ingredients have been used in preventive care for the treatment of dental and oral disorders. Chronic conditions on the teeth with the appearance of plaque and tooth decay are referred to as dental caries which are characterized by toothache and also digestive disorders. Streptococcus mutans is known as the bacteria that most often causes dental caries. Karamunting and rambusa plants have enough potential as antibacterials because there have been many studies that have shown their potential as antibacterial activities. The purpose of this study was to determine the antibacterial activity of ethyl acetate extract of karamunting leaves and rambusa leaves against Streptococcus mutans. Antibacterial activity test using well diffusion method by measuring the diameter of the inhibition zone. The results showed that the ethyl acetate extract of karamunting leaves 1%, 5%, 10%, 15%, 20% had inhibition zone diameters of 4.6 mm, 4.1 mm, 0 mm, 0 mm, 0 mm, respectively while rambusa leaves 1%, 5%, 10%, 15%, 20% had inhibition zone diameters of 4.4 mm, 8.7mm, 9.4 mm, 5.3mm and 8.8mm respectively. The ethyl acetate extract of karamunting and rambusa leaves is known to have weak antibacterial activity in the resistant category.

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETIL ASETAT DAUN RAMBUSA DAN DAUN KARAMUNTING TERHADAP Streptococcus mutans Muhammad Priyadi; Nurul Chusna; Guntur Satrio Pratomo
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.875

Empirically, many natural ingredients have been used in preventive care for the treatment of dental and oral disorders. Chronic conditions on the teeth with the appearance of plaque and tooth decay are referred to as dental caries which are characterized by toothache and also digestive disorders. Streptococcus mutans is known as the bacteria that most often causes dental caries. Karamunting and rambusa plants have enough potential as antibacterials because there have been many studies that have shown their potential as antibacterial activities. The purpose of this study was to determine the antibacterial activity of ethyl acetate extract of karamunting leaves and rambusa leaves against Streptococcus mutans. Antibacterial activity test using well diffusion method by measuring the diameter of the inhibition zone. The results showed that the ethyl acetate extract of karamunting leaves 1%, 5%, 10%, 15%, 20% had inhibition zone diameters of 4.6 mm, 4.1 mm, 0 mm, 0 mm, 0 mm, respectively while rambusa leaves 1%, 5%, 10%, 15%, 20% had inhibition zone diameters of 4.4 mm, 8.7mm, 9.4 mm, 5.3mm and 8.8mm respectively. The ethyl acetate extract of karamunting and rambusa leaves is known to have weak antibacterial activity in the resistant category.

Kualitas Hidup Pasien Gagal Ginjal Kronis yang menjalani Hemodialisis di RSUD Dr. Doris Sylvanus Palangka Raya: Quality of Life of Chronic Kidney Disease Patients on Hemodialysis at Dr. Doris Sylvanus Hospital Palangka Raya Dewi Sari Mulia; Evi Mulyani; Guntur Satrio Pratomo; Nurul Chusna
Borneo Journal of Pharmacy Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v1i1.238

Kidney disease includes various diseases and disorders affecting the kidney function. If not treated immediately then there will be kidney failure. Patients with Chronic Kidney Disease (CKD) require hemodialysis due to impaired endocrine, metabolic, electrolyte and acid-base functions. Hemodialysis is a substitute for kidney function to remove the rest of the metabolism. These hemodialysis actions can affect the quality of life of patients. The purpose of this study was to determine the quality of life of CKG patients undergoing hemodialysis therapy in dr. Doris Sylvanus Hospital Palangka Raya. This research uses the univariate quantitative method with a descriptive approach. Data were collected using a questionnaire adapted from the World Health Organization Quality of Life (WHOQoL)-BREF containing 26 items of questions covering four dimensions: physical, psychological, environmental and social. The sample used in this study as many as 30 people. Based on the assessment of the quality of life in this study showed that physical and psychological dimensions including in moderate quality of life, and environmental and social dimensions including a good quality of life.

Profil Penggunaan Obat Antibiotik Golongan Penisilin di Apotek Rawat Jalan RSUD Kuala Kurun: Profile of Use of Penicillin Class of Antibiotic in Outpatient Pharmacy at Kuala Kurun Hospital Nurul Chusna; Guntur Satrio Pratomo; Lisa Murwanda
Borneo Journal of Pharmacy Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v1i1.246

This study aims to determine the profile of the use of penicillin-class antibiotics in Kuala Kurun Hospital. The method used in this study is the descriptive method, the population in this study were all prescription outpatients that included penicillin group antibiotics at Kuala Kurun Hospital during the period of September-November 2015 totaling 132 prescriptions, all of which were used as samples. Data collection techniques used in the form of documentation is by calculating the use and classifying the antibiotic groups of penicillin based on the type of preparation. Based on the results of the study it was found that the most widely used antibiotic dosage forms in the period September-November 2015 were tablet preparations. The use of Amoxicillin tablets was prescribed for 92 prescriptions with 69.7% usage percentage. Ampicillin tablets are prescribed as many as 18 prescriptions with a usage percentage of 13.6%. Whereas antibiotics in the penicillin group, Amoxicillin syrup preparations total use as many as 22 recipes with a percentage of 16.7%. Based on the visit of patients who came to Kuala Kurun Hospital in the period of September-November 2015 there were 132 prescriptions of patients using penicillin class of antibiotics. After the data is grouped, it is known that the most widely used penicillin antibiotic form is a tablet preparation with Amoxicillin and Ampicillin.

Gambaran Penggunaan Obat Antidiare di 3 Puskesmas Kabupaten Barito Selatan: Description of The Use of Antidiarrheal in 3 South Barito District Health Centers Nurul Chusna; Evi Mulyani; Ahmad Asmadi
Borneo Journal of Pharmacy Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v1i1.247

Diarrhea is a disease characterized by an increase in the frequency of defecation more than three times a day accompanied by changes in the shape and consistency of feces of patients. Bacterial, viral or parasitic infections can cause diarrhea. This study aimed to determine the profile of the use of antidiarrheal drugs for one semester in 3 South Barito District Health Centers namely Bangkuang Health Center, Sababilah Health Center, and Buntok Health Center. The results showed that there were differences in the use of drugs in each Health Center. Based on the type of drug that is most widely used, namely for the Bangkuang Health Center was Zink (1300 prescription), for Sababilah Health Center was Metronidazole (1350 prescription), and for Buntok Health Center was Cotrimoxazole (4650 prescriptions). Based on the age of patients aged 18-60 years for Bangkuang Health Center as many as 120 people, 279 people for Sababilah Health Center, and 315 people for Buntok Health Center. Based on male and female sex, for Bangkuang Health Center were 98 males and 167 females, for Sababilah Health Center were 233 males and 258 females, and for Buntok Health Center were 298 males and 398 females. Further research needed for a long time regarding the use of antidiarrheal drugs in other Health Centers.

Tingkat Kepuasan Pasien terhadap Pelayanan Kefarmasian di Puskesmas Pahandut Kota Palangka Raya: Level of Patient Satisfaction on Pharmaceutical Services in Community Health Centers of Pahandut Palangka Raya Nurul Chusna; Titra Fetriana; Rabiatul Adawiyah
Borneo Journal of Pharmacy Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v1i2.379

This study aims to determine the level of patient satisfaction with pharmaceutical services at the Pahandut Palangka Raya Community Health Center. This research method is descriptive. The sample in this study were 94 respondents, namely outpatients who received pharmacy services at the Pahandut Palangka Raya Community Health Center. The sampling technique in this study used a purposive sampling technique. The results of the study of patient satisfaction with pharmaceutical services based on the type of service obtained a score of 208 data located in the "very satisfied" area on the type of pharmacy staff responsiveness to patients, in the type of hospitality services pharmacy staff obtained a score of 206 data located "very satisfied", the types of clarity of pharmacy services in providing drug information obtained a score of 212 data located in "very satisfied" areas, in the type of drug service speed the score data 199 were found in "very satisfied" areas, in the types of medical services and medical devices the score data was obtained 200 lies in the "very satisfied" area, in the type of waiting room comfort service the 198 score data is located in the "very satisfied" area, and on the type of service the availability of brochures, leaflets, posters, as well as drug/health information is obtained score data 206 lies in the "very satisfied" area. The results of this study indicate that most patients were very satisfied with the pharmaceutical services provided by the Pahandut Community Health Center in Palangka Raya City.

Eribulin Effectiveness and Safety in Metastatic Triple-Negative Breast Cancer: A Narrative Review Meriyani, Herleeyana; Sanjaya, Dwi Arymbhi; Juanita, Rr. Asih; Siada, Nyoman Budiartha; Chusna, Nurul; Ketupapa, Florentina Gabriela
Borneo Journal of Pharmacy Vol. 8 No. 1 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i1.7913

Triple-negative breast cancer is an aggressive and poor prognosis subtype of breast cancer. Eribulin has shown promise in the treatment of metastatic triple-negative breast cancer (mTNBC). This review aimed to provide a specific description, evidence, and discussion of the efficacy and safety of eribulin both as monotherapy and in combination with another agent in patients with mTNBC. The search was conducted in five databases (PubMed, ScienceDirect, PLoS One, Wiley Online Library, and Cochrane Library) towards published articles during the 2013-2023 period. A total of 237 articles were identified. After removing 69 duplicates, 168 articles underwent the screening process and 10 articles met the research criteria. Eribulin monotherapy effectiveness profile includes: overall survival (10.8-17.6 months), progression-free survival (2.8-3.2 months), partial response (21.0%-58.7%), progressive disease (15.5% -47.0%), and stable disease (28.8%-32%). However, there were no cases of complete response. Combination of eribulin with other agents' effectiveness profiles includes: overall survival (8.3-14.5 months), PFS (2.6-8.1 months), partial response (31.8-76.0%), complete response (2.4-8%), progressive disease (8.0-28%), and stable disease (8.0-52.3%). Eribulin monotherapy's safety profile is similar to that of combination therapy. No grade 5 adverse event was reported during monotherapy or in combination with other agents. The grade 4 adverse events reported are neutropenia, leukopenia, thrombocytopenia, anemia, peripheral neuropathy, fatigue, diarrhea, vomiting, dyspnea, back pain, arthralgia, febrile neutropenia, dyspnea, constipation, general physical health deterioration, alopecia. The all-grade adverse events with a percentage above 50% are neutropenia, leukopenia, thrombocytopenia, asthenia, alopecia, elevated AST, elevated ALT, hand-foot syndrome, fatigue, anemia, peripheral neuropathy, oral mucositis, and nausea.

Improvement of Quality and Quantity of Technology-Based Learning in Pharmacy and Medical Laboratory Technology Chusna, Nurul; Novaryatiin, Susi; Purbayanti, Dwi; Mulyani, Evi; Ardina, Rinny; Rahmah, Windya Nazmatur; Pratama, Mohammad Rizki Fadhil
Borneo Journal of Medical Laboratory Technology Vol. 7 No. 2 (2025): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v7i2.7166

The enhancement of technology-based learning in the fields of pharmacy and medical laboratory technology is imperative to keep pace with advancements in healthcare and educational methodologies. This study investigates the strategies and impacts of integrating cutting-edge technologies into the curricula of these disciplines. Key areas of focus include the implementation of virtual simulations, online learning platforms, and interactive multimedia resources. The research highlights how these technologies improve the quality of education by providing students with realistic, hands-on experiences that enhance their practical skills and theoretical knowledge. Additionally, the study explores the scalability and accessibility of technology-based learning, which contributes to increased student engagement and enrollment. By leveraging data analytics and feedback mechanisms, educators can tailor learning experiences to meet individual student needs, thereby improving learning outcomes. The findings suggest that the thoughtful integration of technology not only enriches the educational experience but also prepares students more effectively for the evolving demands of the healthcare industry. This research underscores the necessity of continuous investment in educational technologies to sustain the quality and quantity of learning in pharmacy and medical laboratory technology programs.

Edukasi Cara Penularan dan Pencegahan Penyakit Tuberkulosis (TBC) pada Masyarakat Kota Palangka Raya, Kalimantan Tengah Handayani, Rezqi; Mulyani, Evi; Satrio P, Guntur; Suryadini, Halida; Chusna, Nurul; Adawiyah, Rabiatul; Mulia, Dewi Sari; Ternate, Agustinawati Umi
Jurnal Pengabdian Masyarakat Wadah Publikasi Cendekia Vol 2 No 2 (2025): Jurnal Pengabdian Masyarakat WPC
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/jpmwpc.v2i2.802

Tuberkulosis (TBC) tetap menjadi masalah kesehatan masyarakat yang serius di Indonesia, termasuk Kota Palangka Raya, Kalimantan Tengah, di mana tingkat penemuan kasus dan keberhasilan pengobatan masih membutuhkan peningkatan. Kurangnya pengetahuan masyarakat mengenai cara penularan, gejala, pentingnya deteksi dini, kepatuhan pengobatan, serta adanya stigma sosial menjadi hambatan signifikan dalam upaya eliminasi TBC. Oleh karena itu, kegiatan edukasi yang komprehensif dan terarah sangat dibutuhkan. Tujuan dari pengabdian kepada masyarakat ini adalah untuk meningkatkan pengetahuan dan kesadaran masyarakat Kota Palangka Raya tentang cara penularan dan pencegahan TBC, serta mendorong perubahan perilaku kesehatan. Metode yang digunakan meliputi edukasi informasi terkait pencegahan dan penularan TBC dengan media leaflet, edukasi tentang penyakit TBC pada anak-anak dan edukasi pola hidup sehat dengan melaksanakan kegiatan senam dan pemberian makanan sehat yaitu bubur kacang hijau. Kegiatan ini dilaksanakan di Taman Kota Nyahu Papan Taliwo Kota Palangka Raya, Kalimantan Tengah dengan sasaran pengabdian adalah masyarakat dari usia dini, dewasa, dan lansia. Kegiatan ini berfokus pada penyampaian informasi akurat mengenai penyebab, penularan, gejala, pengobatan, dan langkah-langkah pencegahan TBC. Selain itu, upaya dilakukan untuk mengatasi stigma melalui komunikasi yang empati. Diharapkan, peningkatan pemahaman ini akan mendorong deteksi dini, kepatuhan pengobatan, pengurangan penularan, dan pada akhirnya, berkontribusi pada pencapaian target eliminasi TBC di Kota Palangka Raya.

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