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All Journal Jurnal Wiyata : Penelitian Sains dan Kesehatan Journal Syifa Sciences and Clinical Research (JSSCR) Bioscientist : Jurnal Ilmiah Biologi JOURNAL OF COMMUNITY ENGAGEMENT AND EMPOWERMENT SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Indonesian Journal of Pharmaceutical Education Journal of Health Research Science Jurnal Pharma Bhakta Jurnal Ilmiah Nusantara
Wahyuni, Kumala Sari Poespita Dewi
IIK BHAKTI WIYATA
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Kepatuhan minum obat pada pasien lansia dengan diabetes melitus Sari, Dwi Evi Diyan; Seran, Krisogonus Ephriono; Fajriyah, Shofiatul; Anjani, Ade Giriayu; Wahyuni, Kumala Sari Poespita Dewi
Journal of Health Research Science Vol. 5 No. 02 (2025): Journal of Health Research Science
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Kesehatan Kuningan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34305/51mj0d78

Abstract

Latar Belakang: Kepatuhan pengobatan pada pasien diabetes melitus lanjut usia masih rendah akibat penurunan kognitif dan keterbatasan fisik. Penelitian ini bertujuan mengetahui pengaruh faktor sosiodemografi terhadap kepatuhan pengobatan pada lansia dengan diabetes melitus di Kabupaten Sleman.Metode: Penelitian observasional analitik cross sectional pada 76 lansia dengan diabetes tipe 2 peserta Prolanis Puskesmas. Data diperoleh dari rekam medis dan wawancara menggunakan kuesioner Morisky Green Levine Scale (MGLS). Analisis hubungan dilakukan dengan uji Chi-Square.Hasil: Mayoritas peserta perempuan (61,84%), usia 60–70 tahun (76,32%), dan berpendidikan menengah (55,26%). Tingkat kepatuhan didominasi kategori sedang (53%), diikuti rendah (35%) dan tinggi (12%). Tidak ditemukan hubungan antara faktor sosiodemografi (usia, jenis kelamin, pendidikan, pekerjaan, durasi penyakit, jumlah obat) dan tingkat kepatuhan (p > 0,05).Kesimpulan: Mayoritas pasien lanjut usia dengan diabetes melitus di Kabupaten Sleman memiliki kepatuhan sedang terhadap pengobatan dan tidak ada keterkaitan antara faktor sosiodemografi dengan kepatuhan pengobatan.
Evaluation of Dose Appropriateness in Patients Congestive Heart Failure and Comorbid Chronic Kidney Disease at RSUD Kabupaten Kediri Agustin, Ela; Fajriyah, Shofiatul; Widyaningrum, Esti Ambar; Putri, Adinda Sheisella; Wahyuni, Kumala Sari Poespita Dewi
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 11, No 1 (2026)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v11i1.9346

Abstract

Congestive heart failure (CHF) is a chronic condition requiring long-term therapy. Patients with heart failure accompanied by comorbid chronic kidney disease (CKD) require dose adjustment to prevent drug toxicity. This study aimed to determine the therapeutic profile and dosing appropriateness among patients with congestive heart failure and comorbid CKD hospitalized at RSUD Kabupaten Kediri during the January–December 2022 period. This study employed a retrospective observational design using medical record data with a total sampling technique, resulting in 72 eligible patients. Dose appropriateness was evaluated based on estimated glomerular filtration rate (eGFR) calculated using the Cockcroft–Gault equation and compared with recommendations from The Renal Drug Handbook. The results indicate that the majority of samples in this study were female (54.17%) and aged 45–54 years (41.67%). Most patients had additional comorbidities (80.56%), with anaemia being the most prevalent concomitant condition. Based on CKD staging, the majority of patients were classified as stage 5 CKD (77.78%). Combination therapy involving two medications was the most common treatment pattern (30.57%), with a diuretic plus ARB combination being the most frequently prescribed regimen. The evaluation of dosing appropriateness demonstrated that 69 patients (95.83%) received doses adjusted appropriately to their renal function, while 3 patients (4.17%) received inappropriate dosing. Inappropriate use was identified in prescriptions of spironolactone and acarbose, which should be avoided in patients with low eGFR values. In conclusion, most patients with congestive heart failure and comorbid CKD received therapy with doses appropriately adjusted to renal function. However, cases of inappropriate dosing were still identified, which may increase the risk of adverse effects.
Co-Authors Ade Giriayu Anjani Admaja, Wika Agustin, Ela Anikasari, Erni Dianty Putri Millania Paringsih Dwitania Noerhalizah Eka Sulistyana Esti Ambar Widyaningrum Farida, Umul Hariyani Herlinda Mawardika Hesturini, Rosa J. Indra Fauzi Sabban Irma Tristanti Kalanjana, Chandraqila Khusnul Khulukia, Widya Kusumaratni, Dyah Ayu Lisa Aditama, Lisa Nur Dianawati Oktaviana, Feny Putri, Adinda Sheisella Rohid Zanuar, Muhammad Sari, Dwi Evi Diyan Seran, Krisogonus Ephriono Setiasih Setiasih Shofiatul Fajriyah Umul Farida Yudha Prasetyo, Eko