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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Kesehatan Vokasional JMM (Jurnal Masyarakat Mandiri) Jurnal Surya Masyarakat Journal Syifa Sciences and Clinical Research (JSSCR) Fullerene Journal of Chemistry Jurnal Gema Ngabdi ACADEMICS IN ACTION Journal of Community Empowerment Abdimas UNWAHAS : Jurnal Pengabdian Masyarakat UNWAHAS Jurnal Ilmiah Cendekia Eksakta Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Journal of Pharmaceutical Care Anwar Medika Jurnal Surya Masyarakat PROFESSIONAL HEALTH JOURNAL Indonesian Journal of Community Dedication in Health (IJCDH) Jurnal Kefarmasian Indonesia Sainteknol : Jurnal Sains dan Teknologi Journal of Food Safety and Processing Technology
Nasyanka, Anindi Lupita
Universitas Muhammadiyah Gresik
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Studi in silico : Hubungan Kuantitatif Struktur-Aktivitas Antivirus SARS-COV2 Pada Senyawa Turunan N-4-benzoil-N’-(4-fluorofenil) tiourea Anindi Lupita Nasyanka; Diah Ratnasari; Janatun Na’imah; Dini Kesuma
Journal Syifa Sciences and Clinical Research Vol 4, No 2 (2022): Volume 4 Edisi 2 2022
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v4i2.15119

Abstract

Specific therapies for the SARS-CoV2 virus are still being developed in several countries countries in the world. One of the suspected molecular targets specific to SARS COV2 is the 3CLpro or main protease of the COVID-19 virus. Based on the target of this work, there are similarities between the compounds  N-4-benzoyl-N'-(4-fluorophenyl)thiourea derivatives with their inhibitors. This study aims to develop derivative compounds N-4-benzoyl-N'-(4-fluorophenyl)thiourea as a potential drug candidate inhibiting SARS-CoV2 viral protein using the HKSA method in silicon. Based on the results of the analysis, the best equation for the development of anti-virus SARS-CoV2 was Log 1/C = 0.269 Log P2 – 2.776 Log P + 0.221 cMR +3.195 (n= 8; R = 0.949 S= 0.11399; F=12,119;Sig=0,018). The role of the lipophilic and -containing groups steric can increase its activity as an anti-virus SARS-CoV2 In silico on the modification of the derivative.
Pengendalian Persediaan Suplemen Kesehatan Pada Masa Pandemi Dengan Menggunakan Metode ABC,EOQ,ROP Di Apotek Karang Langit Lamongan Tahun 2021Pe Mila Apriani Hamidah; Anindi Lupita Nasyanka; Norainny Yunitasari
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 3 No 02 (2022): HERCLIPS VOL 03 NO 02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v3i02.3548

Abstract

The COVID-19 outbreak has greatly impacted all sectors, one of which is the increasing number of requests for health supplements to strengthen the immune system from viral attacks. This causes frequent shortages of health supplement stocks in several pharmacies. The purpose of this study was to analyze the implementation of health supplement inventory planning control at Apotek Karang Langit Lamongan by comparing the results of secondary data using the ABC, EOQ, ROP methods. This research is observational with quantitative descriptive data analysis. Data collection is retrospective and the research instrument is a data collection sheet. The results showed that there were 20 types of health supplements in group A (20%) with an income value of Rp. 35,203,380 (69.24%) of the total income. Group B consisted of 33 species (30%) with an income value of Rp. 10,469,200 (20.59%) of the total income. Group C consisted of 55 species (50%) with an income value of Rp. 5,167,585,8 (10,17%) of the total income. Health supplement control is prioritized in group A. In the calculation of EOQ group A starting from 1-152 items and ordering frequency in 3 months as much as 5-23 times, for group B starting from 1-210 items with ordering frequency between 3-5 times, group B starts from 1-210 items with ordering frequency between 3-5 times, C ranging from 1-160 items with a frequency of orders between 1-3 times. ROP group A starts from 1-58 items, for group B starts from 0-52 items and in group C starts from 0-22 items. Therefore, the results of the ABC method analysis, EOQ, SS, ROP calculations can be used to control the planning of health supplement procurement at Karang Langit Pharmacy. Keywords: control, health supplement planning, ABC analysis, EOQ, SS, ROP.
Uji Hedonisme Sediaan Gel Antijerawat Dari Jeruk Nipis diah ratnasari; Riskha Aulia; Anindi Lupita Nasyanka
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 2 No 1 (2020): Herclips vol.2 no.1
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v2i1.2189

Abstract

Clean, smooth, and disease-free facial skin is a dream. However, the reality is that many people have skin problems. The skin problem that often occurs is acne. One way to treat acne is by using herbal preparations. Herbal plants that have anti-acne properties include Citrus aurantiifolia and menthol. The purpose of this study was to make antiacne gel preparations from Citrus aurantiifolia and menthol. There are also stages of this research, including formula making, production and physical evaluation of preparations to obtain the best dosage formulas. In addition, the determination of the optimum stability and formula is obtained from the physical evaluation of the gel preparation which includes organoleptic and hedonism test. Keyword : herbal, Citrus aurantiifolia, menthol, hedonism test
EDUKASI OBAT TRADISIONAL PADA SISWA PASSION KESEHATAN SMA MUHAMMADIYAH 1 GRESIK Diah Ratnasari; Anindi Lupita Nasyanka; Janatun Na'imah
Indonesian Journal of Community Dedication in Health (IJCDH) Vol 2 No 02 (2022): IJCDH VOL 02 NO.02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/ijcdh.v2i02.4160

Abstract

Pengobatan sendiri atau yang sering disebut swamedikasi adalah salah satu upaya masyarakat untuk menjaga kesehatannya sendiri. Pada prakteknya, swamedikasi bisa menjadi akar masalah terkait penggunaan obat (Drug related problem) karena kurangnya pengetahuan tentang obat dan penggunaannya. Selama beberapa tahun terakhir, perilaku swamedikasi oleh masyarakat untuk membantu mencegah dan mengobati kondisi medis mereka telah menjadi semakin luas (Oktavia dan Aisyah, 2019). Hasil Riset Kesehatan Dasar (Riskesdas) menunjukkan 35,2% masyarakat Indonesia menyimpan obat di rumah tangga, baik diperoleh dari resep dokter maupun dibeli sendiri secara bebas. Proporsi masyarakat yang menyimpan obat keras tanpa resep mencapai 81,9%, diantaranya termasuk antibiotik. Data ini membuktikan bahwa sejumlah besar masyarakat melakukan swamedikasi, untuk itu harus diimbangi dengan informasi yang memadai, sehingga tidak terjadi kesalahan (Kemenkes, 2013).
PENYULUHAN PEMANFAATAN BENGKOANG DAN BIJI PEPAYA SEBAGAI KOSMETIK DI SMA MUHAMMADIYAH 1 GRESIK Janatun Na'imah; Anindi Lupita Nasyanka; Diah Ratnasari
Indonesian Journal of Community Dedication in Health (IJCDH) Vol 2 No 02 (2022): IJCDH VOL 02 NO.02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/ijcdh.v2i02.4158

Abstract

Lulur tradisional merupakan lulur yang terbuat dari rempah-rempah dan tepung yang teksturnya kasar. Banyak tanaman yang dapat dimanfaatkan sebagai lulur tradisional. Biji papaya mengandung papain dapat digunakan sebagai bahan aktif dalam pembuatan krim pembersih kulit, dan pati bengkuang mengandung flavonoid yang mempunyai manfaat melembabkan kulit. Kedua bahan dihaluskan dan kemudian di buat lulur dalam bentuk serbuk. Oleh karena itu, pada pengabdian kepada masyarakat Program Kemitraan Masyarakat ini dilakukan penyuluhan/pemberian informasi yang benar terkait kosmetik tradisional berupa lulur yang menjadi kebutuhan masyarakat agar terhidar dampak buruk bagi kesehatan serta pelatihan cara membuat lulur tradisional dari papaya dan bengkoang. Selain itu juga dilakukan pre-test dan post-test serta tanya jawab untuk mengukur pemahaman masyarakat terkait materi yang diberikan sebagai indicator keberhasilan pengabdian kepada masyarakat ini. Luaran pada Program Kemitraan Masyarakat ini adalah 97,90 % peserta mampu memahami tentang pemanfaatan papaya dan bengkoang sebagai lulur alami. Kata kunci : lulur, kosmetik alami, papaya, bengkoang
Aplikasi Games Penggolongan Obat di Indonesia pada Kelas Passion Kesehatan SMAM 1 Gresik anindi lupita nasyanka; Janatun Na'imah; Siti Nur Asiyah
Indonesian Journal of Community Dedication in Health (IJCDH) Vol 2 No 02 (2022): IJCDH VOL 02 NO.02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/ijcdh.v2i02.4156

Abstract

Masa pandemi COVID-19 ini membuat masyarakat terbiasa melakukan pengobatan sendiri terhadap penyakitnya. Pengobatan sendiri cenderung aman, akan tetapi bila masyarakat kurang memahami informasi obat/ produk yang digunakan maka akan menimbulkan efek merugikan baik secara kesehatan, sosial, maupun ekonomi. Kelas passion di SMA Muhammadiyah 1 Gresik terdiri dari beberapa passion antara lain kewirausahaan, kesehatan, dan lain-lain. Kelas passion kesehatan diadakan dalam rangka mewadahi siswa-siswa yang tertarik dengan dunia kesehatan. Oleh karena itu, sebagai kader kesehatan disekolah maupun di rumahnya maka diperlukan edukasi terkait informasi obat yaitu penandaan obat dan penggolongannya di Indonesia. Pelajar merupakan usia remaja dengan keingintahuan dan kreatifitas tinggi. Dalam melakukan edukasi diperlukan media yang menarik perhatian dan mudah diingat oleh pelajar tersebut. PKM dilaksanakan mulai 2-25 Februari 2022 dengan 3 tahapan kegiatan. Tahapan pertama pembelajaran interaktif kepada siswa terkait penandaan dan penggolongan obat. Tahap kedua, melakukan pendampingan kepada siswa untuk mengimplementasikan media edukasi dan games pada civitas sekolah dalam pameran passion. Tahap ketiga, terlaksananya pameran passion terkait edukasi dan games penandaan dan penggolongan obat. Hasil kegiatan pengabdian masyarakat kepada siswa kelas X Passion kesehatan SMA Muhammadiyah 1 Gresik menggunakan media aplikasi game interaktif dapat meningkatkan pengetahuan 100% siswa. Selain itu, siswa dapat mengaplikasi ilmunya melalui pameran kesehatan yang diapresiasi oleh seluruh civitas akademika. Kata kunci—3-5 Kelas passion, penggolongan obat, SMA
PENGGUNAAN VIDEO CONFERENCE DALAM EDUKASI PENULARAN COVID-19 PADA MASYARAKAT DESA MOJOGEDE, BALONGPANGGANG KABUPATEN GRESIK Anindi Lupita Nasyanka; Heru Baskoro; Janatun Naimah
ABDIMAS UNWAHAS Vol 6, No 2 (2021)
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/abd.v6i2.5684

Abstract

Penularan Covid-19 di Gresik menempati urutan ke-3 terbesar di Jawa Timur. Desa Mojogede, kecamatan Balongpanggang di kabupaten gresik merupakan salah satu wilayah dengan usia produktif tinggi, dimana resiko penularan pada usia tersebut sangat tinggi. Oleh karena itu, pengabdian masyarakat bertujuan untuk meningkatkan pemahaman masyarakat desa Mojogede, sehingga mengurangi resiko penularan COVID-19 pada beberapa bulan kedepan. Metode yang digunakan dalam pengabdian ini ceramah dan diskusi menggunakan media video konferensi ZOOM kepada 25 peserta. Evaluasi hasil pemahaman menggunakan analisa uji t berpasangan. Berdasarakan uji tersebut tidak ada perbedaan bermakna (sig>0,05) hasil pretes dan postes, Namun, hasil postes (91,2%) lebih baik dibanding pretes (87,2%) sehingga terdapat peningkatan pengetahuan masyarakat. Selain itu, penggunaan video konferensi harus memperhatikan kesiapan sinyal internet dari peserta sehingga kegiatan dapat berjalan efektif.Kata kunci­ : COVID-19 Video Konferensi, Desa Mojogede
FORMULASI EMULGEL EKSTRAK ETANOL DAUN JAMBU BIJI (Psidium guajava Linn.) SEBAGAI ANTI ACNE CLEANSER Anindi Lupita Nasyanka; Janatun Na’imah; Norainny Yunitasari
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol 17, No 2 (2020): Jurnal Ilmu Farmasi & Farmasi Klinik Vol. 17 N0. 02 Desember 2020
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (510.585 KB) | DOI: 10.31942/jiffk.v17i2.4072

Abstract

ABSTRACT Acne is a major problem for teenagers, especially at puberty. Guava leaves (Psidium guajava Linn .) are plants that contain several secondary metabolites, including the tannins, triterpenoids, glycosides, and flavonoids, which have anti-acne activity. So far, acne reduction is still being done using synthetic cosmetics. However, synthetic cosmetics often irritate, so that herbal cosmetics are an alternative. Formulation of herbal cosmetics for acne need to do. This study aims to determine the best formula for anti-acne cleanser emulgel from the ethanol extract of guava leaves based on the physical evaluation. Guava leaf extract as obtained by the maceration method uses ethanol as a solvent, then an emulgel was prepared with an extract concentration of F1 (5%) and F2 (10%). Emulgel characteristics were determined by physical evaluation including organoleptic, pH, emulsion type, viscosity, spreadability, homogeneity, foam stability, power clean, and hedonism. The best formula was determined by the number of tests that meet the requirements and are liked by consumers. The results had shown F1 is the best formula based on physical evaluation. Keywords: Acne, emulgel, guava leaves, physical evaluation
Kajian Kajian In Silico Aktivitas Ekstrak Daun Mangga (Mangifera indica L.) Sebagai Antidiabetes Tipe 2 Janatun naimah; Anindi Lupita Nasyanka; Diah Ratnasari; Siti Nur Asiyah
PROFESSIONAL HEALTH JOURNAL Vol 5 No 1sp (2023): Special Issue Outcome PDP
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54832/phj.v5i1sp.500

Abstract

Type 2 diabetes mellitus is the most common type of diabetes in the world. Type 2 diabetes mellitus is caused by an increase in blood sugar due to a decrease in low insulin secretion by the pancreas gland. Pharmacological therapy for type 2 diabetes, namely oral antidiabetic drugs (OAD) or insulin such as acarbose, metformin, or voglibose has been reported to have side effects. Side effects that occur, such as gastrointestinal disturbances (diarrhea and flatulence), liver disorders, dizziness, nausea and vomiting. Thus, herbal ingredients are an alternative in the treatment of diabetes mellitus. In this study, mango leaf extract, namely mangiferin, was suspected as an antidiabetic compound. The purpose of this study was to determine the interaction of mangiferin which is an extract of mango leaves (Mangifera Indica L.) with -glucosidase in silico. The results showed that mangiferin as a type 2 antidiabetic compound by producing an G value between -glucosidase and mangiferin of -38.89 kcal/mol. The interaction that occurs is hydrogen bonding between mangiferin and amino acid residues Glu553, Asn551, Arg500 and Tyr460, Phe461. Keywords: α-glucosidase, in silico, mangiferin, mango leaf,
Studi In silico : Toksisitas Senyawa Potensial Sebagai Antikanker Turunan N-((4-Fluorofenil) Karbamatiol) Benzamida Anindi Lupita Nasyanka; Diah Ratnasari; Jannatun Na'imah; Siti Nur Asiyah
Journal of Pharmaceutical Care Anwar Medika (J-PhAM) Vol 5 No 2 (2023): Journal of Pharmaceutical Care Anwar Medika (J-PhAM)
Publisher : STIKES Rumah Sakit Anwar Medika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36932/jpcam.v5i2.144

Abstract

The potential derivative compound N-((4- Fluorophenyl ) Carbamatiol ) Benzamide a has been predicted to have good activity at the sirtuin-1 receptor which plays a role in triggering cancer on the p53 protein . Toxicity plays a very important role in the safety of the drugs used in the development of new drugs. Therefore, this study aims to determine the toxicity prediction of NBFFT derivatives as anticancer drug candidates. The method used is quantitative descriptive analysis based on the results of in silico toxicity predictions using the Read Across method through the ProTox web server system. on NBFFT derivatives in the ChemBL database with comparators of tenovin and hydroxyurea. The results showed that the derivative compound N-((4 -Fluorophenyl ) carbamatiol ) Benzamide a as an anticancer candidate, it is included in category V (possibly dangerous if consumed) which corresponds to tenovin as a comparison. In addition, predictions of hepatotoxic events were found in these derivative compounds through the MMP stress response pathway, p53, and the nuclear cell nucleus receptor (AhR) type signaling pathway.
Co-Authors Arizka, Hawwin Elina Azizah, Viaristi Amelina Diah Ratnasari Diah Ratnasari Dini Kesuma Firmani, Ummul Heni Lutfiyati, Heni Heru Baskoro Illahi, Arha Addina indahsari, dita dwi Janatun Naimah Janatun Na’imah Jannatun Na'imah luthfi, Sania al Luthfi, Saniya Al Maesaroh, Dewi Mila Apriani Hamidah Nastiti Trikurniadewi Na’imah, Janatun Norainny Yunitasari Norainny Yunitasari Novitasari, Rikha Anggun Novrianti, Enni Nur Imtihani, Hilya Nur’aini, Farida Octaviary, Niken Laras Pemta Tiadeka Prastiyo, Danu Putri Octavia, Putri Ramadhanti, Nadya Riskha Aulia shofiyah, lailatus Siti Asiyah Siti Nur Asiyah Siti Nur Asiyah Siti Nur Asiyah Suedi, Prapto Utami, Primanitha Ria Yunitasari, Norainny Zulfiyana, Lindah Isna