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All Journal Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya SRIWIJAYA JOURNAL OF MEDICINE Majalah Patologi Indonesia Medical and Health Science Journal Jurnal Ners Community Development Journal: Jurnal Pengabdian Masyarakat International Islamic Medical Journal Prosiding Seminar Nasional Pengabdian Kepada Masyarakat
Lysa Veterini
Universitas Nahdlatul Ulama Surabaya
Religion Humanities Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Journal : Medical and Health Science Journal

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Synchronization of Sputum Conversion and Resolution of Intensive Phase Lesion Areas on Thorax X-rays Determinants of Prognosis for Pulmonary Tuberculosis Therapy Ambarsari, Utami; Arimbi, Muzaijadah Retno; Veterini, Lysa; Indrianto, Yunita Lestari; Candini, Naura Anindya; Notobroto, Hari Basuki
Jurnal Ilmu Kesehatan dan Kesehatan Vol 7 No 02 (2023): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v7i02.4565

Abstract

Background: Pulmonary tuberculosis (TB) is a chronic infectious disease caused by the bacterium Mycobacterium tuberculosis. Diagnosis of TB can be confirmed in two ways, namely bacteriological diagnosis (if AFB sputum is found (+) and clinical diagnosis is (if BTA sputum is found (-), but chest X-ray is (+) TB). Objective: to determine the alignment of sputum conversion and extensive resolution of intensive phase lesions on chest radiographs which determine the prognosis of pulmonary TB therapy. Methods: The study design was a retrospective cohort analytic with a retrospective longitudinal study design. Data from medical records of pulmonary TB patients who have undergone therapy for six months or more at the Pulmonary Polyclinic RSI Jemursari Surabaya. The number of samples was 48 patients aged 41-60 years. All of these pulmonary TB patients were smear positive (BTA+). X-ray examination was done before and after therapy. Results: analysis using the Wilcoxon Signed Rank test to assess differences in the grade of lung lesions before and after therapy, obtained p = 0.003 (p <0.05) meaning there is a significant difference. Sputum conversion was also carried out after therapy, 89.6% of TB patients in this study experienced sputum conversion (BTA negative). To determine the alignment of sputum conversion with the resolution of lesion area, Kappa coefficient analysis K=0.033 (p>0.05) was performed with the results of 50% of patients, 47.9% showed improvement in lung lesions and sputum conversion, while 2.1% showed no improvement of lung lesions and no sputum conversion. The rest, 50% showed no congruence in the results of lung lesion repair and sputum conversion. Conclusion: The results of Kappa coefficient analysis showed that K=-0.110 (p>0.05) showed that there was no congruence between the results of chest x-ray examination of lung lesions before and after therapy (improved or not) with sputum conversion
Prevalence, Risk Factors, and Management of Hansen’s Disease in Indonesia: Evidence from A Systematic Literature Review Sinantryana Widyaswari, Meidyta; Veterini, Lysa; Masdan Salim, Hotimah
Jurnal Ilmu Kesehatan dan Kesehatan Vol 9 No 2 (2025): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v9i2.8020

Abstract

Background: Hansen’s disease (leprosy) continues to be a public health concern in Indonesia, which ranks among the countries with the highest case numbers globally. Despite national control programs, the detection of new cases and disability rates suggests ongoing transmission and delays in diagnosis. A clearer understanding of prevalence, risk determinants, and management approaches is critical to strengthen interventions. Methods: A systematic literature review was performed using PRISMA guidelines. Relevant studies published between 2014 and 2024 were identified from PubMed, Scopus, and Google Scholar. Eligible publications included original research or program evaluations conducted in Indonesia. From 423 records initially screened, 76 full texts were assessed, and 22 articles met the inclusion criteria. Extracted data included prevalence, associated risk factors, and management strategies. Results: The reviewed studies originated from multiple regions such as Java, Sulawesi, Papua, and Maluku. Study designs comprised cross-sectional surveys, case–control studies, cohort analyses, and program evaluations. Prevalence varied substantially, with Papua, Sulawesi, and Maluku reporting the highest burdens. Commonly reported risk factors were poverty, overcrowded housing, malnutrition, genetic predisposition, and persistent social stigma. Household exposure and treatment delay were additional contributors to transmission. Management strategies mainly emphasized multidrug therapy (MDT) adherence, disability prevention, and stigma reduction. Community education and early case detection programs were associated with improved outcomes. However, several barriers remain, including incomplete adherence, inadequate health worker training, and limited psychosocial support. Conclusion: Hansen’s disease in Indonesia remains endemic in several provinces and is shaped by interconnected socioeconomic and biological factors. While MDT has reduced transmission, substantial gaps exist in disability prevention and stigma management. Enhanced surveillance, improved early detection, and stronger integration of community-based and psychosocial strategies are urgently needed to support national and global elimination goals.
Co-Authors Achmad Yarziq Mubarak Salis Salamy Agnovianto, Yuriske Ailany, Erla Syah Dilla Ainiyah Fairus Algristian, Hafid Alkatiri, Wardah Ambarsari, Utami Arimbi, Muzaijadah Retno Aufar Zimamuz Zaman Al Hajiri Bintarti, Tri Wahyuni Candini, Naura Anindya Devyana Dyah Wulandari FARIKHAH, ZUMROTUL Fariska Zata Amani Hari Basuki Notobroto Hidayatul Ulya Indrianto, Yunita Lestari Kurniasari, Diyan Wahyu Masdan Salim, Hotimah Mohammad Nasir Novera Herdiani, Novera Nur Azizah AS Prima Surya Ardiansyah Putri, Winawati Eka Salim, Hotimah Masdan Savitri, Ardyarini Dyah Sinantryana Widyaswari, Meidyta Sjahjenny Mustokoweni, Sjahjenny Syihabuddin Farid Wibowo, Novan Kurnia Wijaya, Afira Febriani Surya Wijaya, Annisa' Dharmestha