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All Journal JPMS (Jurnal Pendidikan Matematika dan Sains) Widya Wacana : Jurnal Ilmiah Bioeksperimen: Jurnal Penelitian Biologi BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) Bio-Lectura Educatif: Journal of Education Research Buletin KKN Pendidikan Didaktika: Jurnal Kependidikan Buletin Pengembangan Perangkat Pembelajaran Bioscientist : Jurnal Ilmiah Biologi Educatif: Journal of Education Research Warta LPM Edubiotik : Jurnal Pendidikan, Biologi dan Terapan Sasambo: Jurnal Abdimas (Journal of Community Service) Indonesian Journal on Learning and Advanced Education (IJOLAE)
Hariyatmi
Universitas Muhammadiyah Surakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Social Sciences Other

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Pengaruh Konsumsi Minuman Instan dengan Frekuensi Berbeda Terhadap Kadar Ureum Darah Mencit (Mus musculus) Mulyatmo, Agung; Hariyatmi, Hariyatmi
Bioeksperimen: Jurnal Penelitian Biologi Vol 1, No 1: March 2015
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/bioeksperimen.v1i1.315

Abstract

Minuman instan yang dikemas dalam kantong plastik dapat dijual dan ditemukan pada toko-toko, warung kecil, dan pedagang kaki lima dengan bebas. Masyarakat tidak menyadari bahwa mengkonsumsi minuman instan berlebihan dapat mengganggu kesehatan, karena dalam komposisi minuman instan tersebut terdapat bahan pemanis buatan. Penelitian ini bertujuan untuk mengetahui pengaruh konsumsi minuman instan dengan frekuensi berbeda terhadap kadar ureum darah mencit (Mus musculus). Penelitian dilakukan dengan metode eksperimen, yang mengguna-kan sampel 20 ekor mencit jantan, berumur 2-3 bulan dan berat 20-40 g yang terbagi ke dalam 4 kelompok, yaitu Placebo, kelompok 1, kelompok 2, dan kelompok 3. Bahwa pemberian minuman instan dengan volume 0,5 ml/20g BB selama 10 hari ada pengaruh terhadap kadar ureum darah mencit (Mus musculus). Kemudian dilakukan uji lanjut Duncan antara kelompok perlakuan placebo, perlakuan 1, dan perlakuan 2 tidak menunjukkan hasil yang bermakna, sedangkan ke-lompok perlakuan 3 yang menunjukkan perlakuan yang paling berpengaruh terhadap kadar ureum darah mencit (Mus musculus). Sehingga dari hasil penelitian dan analisa data dapat disimpulkan bahwa pemberian minuman instan merk Marimas rasa jeruk dengan volume 0,5ml/20 g BB berpengaruh terhadap kadar ureum darah mencit (Mus musculus), dan perlakuan yang paling berpengaruh yaitu kelompok perlakuan 3 dengan pemberian minuman sachet merk Marimas rasa jeruk tiga kali sehari diwaktu pagi, siang dan sore selama 10 hari dibandingkan dengan kelompok placebo, perlakuan 1 dan perlakuan 2.
Pilot Study of Digital Competency Mapping of Indonesian Preservice Teachers: Rasch Model Analysis Muhammad Luthfi Hidayat; Shemsu Gulta Abdurahman; Dwi Setyo Astuti; Ratna Prabawati; Sofyan Anif; Hariyatmi Hariyatmi; Fathul Zannah
Indonesian Journal on Learning and Advanced Education (IJOLAE) Vol. 7, No. 1, January 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/ijolae.v7i1.23935

Abstract

Typically, biology students pursue natural sciences. As the world becomes increasingly interconnected and reliant on digital technologies and platforms, it is essential to evaluate their technological preparedness. This study aims to validate a mapping instrument of the digital competence of pre-service Biology teachers in a leading private university in Indonesia. The analysis used the Rasch model to measure the validity and reliability of questionnaire instrument utilizing the Logit Value of Item (LVI). The Digital competency (Digcom) questionnaire contains 36 statements in the Indonesian language (Bahasa). This questionnaire aims to record respondents' answers to digital skills for preservice teachers. The statement is adapted from the digital competence area for EU citizens combined with the Digital Literacy guidelines of the Indonesian Ministry of Communication and Information. The result of the retranslation has been validated to remove the ambiguity of each item of the statement by English language experts. The pilot research was conducted on preservice teachers from different backgrounds (gender, department, and year of study) in a private University (n=261). The findings indicated that all the items were deemed acceptable as they met the criteria for the PTMEA-CORR range, MNSQ outfit, and ZSTD outfit. This study is among the few that have explored the digital competency framework of preservice teacher students in Indonesia, specifically in relation to the difficulty level of each competency area.
EFFECT OF Peperomia pellucida EXTRACT ON BLOOD GLUCOSE LEVELS AND LEUKOCYTE COUNTS IN MALE WHITE RATS (Rattus norvegicus) Widya Gita Cahyanti; Hariyatmi Hariyatmi
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol. 13 No. 1 (2026): Biolink August
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v13i1.18092

Abstract

Peperomia pellucida is a wild plant traditionally known to be rich in secondary bioactive compounds and has great potential as a natural antidiabetic agent. This study aimed to test the effect of Peperomia pellucida extract on blood glucose levels and leukocyte counts in male white rats (Rattus norvegicus). An experimental study using a Completely Randomized Design (CRD) consisted of 6 treatment groups with 4 replications over 28 days. Rats were conditioned to hyperglycemia using alloxan and then treated with distilled water (P0), 0.5% Na-CMC (P1), 5 mg glibenclamide (P2), and Peperomia pellucida extract at doses of 400 mg/kg BW (P3), 500 mg/kg BW (P4), and 600 mg/kg BW (P5). Data were analyzed using Welch's ANOVA followed by the Games-Howell post hoc test. The results showed that rats treated with Peperomia pellucida extract at all doses (400, 500, and 600 mg/kg BW) exhibited a significant reduction in blood glucose levels with similar effectiveness among doses (p < 0.05). In contrast, no significant differences in leukocyte count were observed among treatment groups (p > 0.05). It can be concluded that treatment with Peperomia pellucida extract at a dose of 400 mg/kg BW for 28 days exhibited antihyperglycemic activity without affecting leukocyte parameters during the treatment period.
Antihyperuricemic Activity of Peperomia pellucida (L.) Kunth Ethanol Extract and Its Effects on Relative Kidney Weight in Rats Riska Dewi Rahmawati; Hariyatmi
Bioscientist : Jurnal Ilmiah Biologi Vol. 14 No. 3 (2026): September
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v14i3.21339

Abstract

This study aimed to evaluate the effectiveness of ethanolic extract of Peperomia pellucida in reducing blood uric acid levels while assessing its subchronic effects on relative kidney weight. An in vivo experiment was conducted using 24 male white rats (Rattus norvegicus), which were randomly allocated into six treatment groups (4 rats per group): a normal control (P0), a negative control receiving 0.1% Na-CMC (P1), a positive control receiving allopurinol at 1.8 mg/200 g body weight (BW) (P2), and three groups receiving P. pellucida extract at doses of 100 mg/kg BW (P3), 150 mg/kg BW (P4), and 200 mg/kg BW (P5). Hyperuricemia was induced by intraperitoneal administration of potassium oxonate at 250 mg/kg BW. Treatments were administered daily for 28 days, followed by measurement of final blood uric acid levels using Point-of-Care Testing and determination of the relative kidney organ index. Welch’s ANOVA showed a significant effect of extract administration on the reduction in blood uric acid levels (F(5, 7.739) = 14.630; p = 0.001). ANCOVA further confirmed significant differences in treatment effectiveness among the groups (F(5, 17) = 3.897; p = 0.015). The 200 mg/kg BW dose (P5) produced the greatest reduction in uric acid levels, reaching 46.06 ± 10.80%, and was statistically comparable to the positive allopurinol control (50.95 ± 13.19%; p > 0.05). In contrast, the Kruskal–Wallis test showed no significant differences in the relative kidney organ index among groups (H(5) = 4.262; p = 0.512), with mean values ranging from 0.82 ± 0.06% to 0.96 ± 0.54%. These findings indicate that P. pellucida extract at 200 mg/kg BW effectively reduces blood uric acid levels without causing significant changes in relative kidney weight during 28 days of administration.
Co-Authors Abdurrahman, Shemsu Gupta Ade Fiqri Setyanto, Ade Fiqri Agung Mulyatmo Agung Mulyatmo, Agung Andi Saputro Andriyani, Fitriana Anggie Iim Setyoningsih Anggun Ella Indriyani Annur Indra Kusumadani Ardian Puguh Setia Budi Arum Dyah Ripdiyanti Ayu, Ernaningsih Diah Chita Yunita Ryan Nugroho D Djumadi Denik Dwi Septiety Dhamayani, Monica Elen Dianita Rifqia Putri Dwi Setyo Astuti Dyah Arifiyanti Ekan Faozi Endah Putri Novi Arti Endang Setyaningsih Fathul Zannah Guntur Nurcahyanto Harun Joko Prayitno Hevi Al Azizah Riani Ima Aryani Julia Larasati Khasanah, Nurul Uswatun Kurnia Hannyda Umamy Ma?rifah, Qa?ilin Mashudi, Sugeng Mazwar Ismiyanto Ma’rifah, Qa’ilin Muhammad Luthfi Hidayat Novi Alya Fatharani Nugroho, Muhammad Adha Bisma Cahyo Paramitha Cahyani Prabawati, Ratna Praditya Panji Prabowo Prasty, Marissa Oktavia Pungky - Pradita Putri Agustina Rachmanisa , Ashari Raharjo, Wahyu Tri Budi Ratna Prabawati Riska Dewi Rahmawati Ristiyani Wijayanti Rofi Safi’i Ahmad Susetya Rohmad Darmawan Septiety, Denik Dwi Shemsu Gulta Abdurahman Siti Rohmi Sofyan Anif Supriyanto Supriyanto Supriyanto Supriyanto Supriyanto Supriyanto Tabriz, Shofiyah Azzahro Tamamah , Vina Teuku Nanda Saifullah Sulaiman Tukimin Bin Sansuwito Wahyuni, Dian Tri Widianti , Tri Widya Gita Cahyanti Wijayanti, Ristiyani Yasir Sidiq