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All Journal JURNAL GIZI INDONESIA The Indonesian Journal of Public Health The Indonesian Biomedical Journal Jurnal Plastik Rekonstruksi Jurnal Respirasi (JR) World Nutrition Journal IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) Archives of The Medicine and Case Reports Jurnal Ilmu Kesehatan Indonesia (JIKSI) Majalah Anestesia & Critical Care (MACC) Tarumanagara Medical Journal Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute
Nurul Ratna Mutu Manikam
Department Of Nutrition, Faculty Of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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SCREEN TIME ON WEEKDAY AND WEEKEND AMONG HEALTH COLLEGE STUDENTS AND THE CORRELATION TO NUTRITIONAL STATUS Farapti, Farapti; Puspasari, Devi; Astutik, Erni; Fadilla, Chusnul; Nurul Ratna Mutu Manikam
The Indonesian Journal of Public Health Vol. 20 No. 1 (2025): THE INDONESIAN JOURNAL OF PUBLIC HEALTH
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijph.v20i1.2025.107-119

Abstract

Introduction: The prevalence of obesity in Indonesia reached 21.8% in 2018 and increased by 6.4% compared to 2013. Low physical activity is known as a risk factor of obesity. College students’ activities are closely related to use of screen time. Aims: To identify the activities of screen time for assignments and non-assignments on weekdays and weekends among college student and analyze its relationship with body mass index (BMI).  Methods: This study was conducted in 2018 with a cross sectional design among undergraduate students at the Faculty of Public Health, Universitas Airlangga, Indonesia, conducted in 2018. The screen time questionnaire was adapted from Sedentary Behavior Questionnaire. The correlation between screen time duration and BMI was analysed by Spearman test. Results: The female subjects were dominant (81.1%) and 28.4% of subjects as overweight-obese. The screen time duration in non-assignment activity on weekends has a positive correlation with the nutritional status of health college students (p 0.000, r 0.49), particularly duration of social networking sites and listening to music were more significant in obese than normal. The use of smartphones takes a high part, approximately 4 hours 20 minutes both on weekdays and on weekends. Conclusion: The screen time duration in non-assignment activity on weekend was associated to nutritional status of health college students. Health college students are encouraged to reduce screen time for non-assignment activities on weekends and to use wisely several smartphone applications or social networking sites to control body weight and achieve a balanced nutritional status.
Efek pemberian suplementasi vitamin D terhadap kejadian kekambuhan pasien inflammatory bowel disease: An evidence-based case report Hidayat, Astriliana Febrianawati; Manikam, Nurul Ratna Mutu
Tarumanagara Medical Journal Vol. 7 No. 1 (2025): TARUMANAGARA MEDICAL JOURNAL
Publisher : Fakultas Kedokteran Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/tmj.v7i1.34092

Abstract

Inflammatory Bowel Disease (IBD), yang mencakup Crohn’s Disease (CD) dan Ulcerative Colitis (UC), merupakan penyakit radang kronis saluran cerna yang dapat timbul berulang. Pasien IBD rentan mengalami defisiensi mikronutrien termasuk vitamin D akibat gangguan absorpsi, malnutrisi, dan peradangan kronis. Beberapa studi menunjukkan bahwa vitamin D mempunyai peran imunomodulator dan antiinflamasi yang berpotensi menurunkan angka kekambuhan IBD. Studi ini bertujuan untuk mengevaluasi efektivitas suplementasi vitamin D dalam menurunkan angka kekambuhan pada pasien dengan IBD melalui telaah bukti ilmiah terkini. Metode pencarian literatur dilakukan melalui basis data PubMed, CENTRAL, dan Google Scholar hingga Februari 2025. Artikel yang diseleksi meliputi studi uji klinis acak dan tinjauan sistematik/meta-analisis. Proses seleksi mengikuti alur PRISMA (preferred reporting items for systematic reviews and meta-analyses) dan dinilai menggunakan pedoman Oxford Centre for Evidence-Based Medicine. Studi ini didapatkan dua artikel memenuhi kriteria inklusi yaitu satu artikel meta-analisis dan satu artikel uji klinis acak. Kedua studi menunjukkan suplementasi vitamin D dapat menurunkan risiko kekambuhan klinis pada pasien IBD terutama signifikan pada pasien CD, bahkan pada pemberian dosis tinggi (2000 IU) dapat menurunkan kadar TNF-α dan meningkatkan kadar serum vitamin D, meskipun tidak signifikan terhadap semua penanda inflamasi setelah penyesuaian. Suplementasi vitamin D menunjukkan potensi dalam menurunkan kekambuhan dan meningkatkan kualitas hidup pasien IBD terutama pada pasien CD. Namun, dibutuhkan lebih banyak studi dengan metodologi yang seragam untuk menentukan dosis, durasi, dan rute pemberian optimal.
Effect of Omega-3 Supplementation on Psoriasis Severity: An Evidence-Based Case Report Basalamah, Tarafainy; Nurul Ratna Mutu Manikam
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 3 (2025): September 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i3.1599

Abstract

Background: Psoriasis is a chronic inflammatory skin disorder often associated with significant morbidity and limited efficacy of conventional treatments, which may also cause adverse effects. Omega-3, with their anti-inflammatory and immunomodulatory properties, have been proposed as a potential adjunctive therapy for managing psoriasis. This evidence-based case report (EBCR) aims to evaluate the efficacy of omega-3 supplementation in improving clinical outcomes in patients with psoriasis. Objective: To determine the effect of omega-3 supplementation on changes in Psoriasis Area and Severity Index (PASI) scores in psoriasis patients. Methods: Literature search was conducted using advanced searching in three large databases: PubMed, Cochrane Library, and ProQuest. MeSH terms, advanced search and eligibility criteria were used for title and abstract screening after removing duplicates. Critical assessment tools and levels of evidence of the final articles are based on the Oxford Center for Evidence-Based Medicine. Results: Three systematic reviews and meta-analyses and one RCTs met the PICO and eligibility criteria that had been set. Three of the studies demonstrated a modest but statistically significant reduction in PASI scores with omega-3 PUFA supplementation, particularly when combined with conventional therapies. A study showed limited or non-significant effects when omega-3 was used alone. Conclusion: Omega-3 supplementation demonstrates a beneficial effect in reducing disease severity in patients with psoriasis, as evidenced by improvements in PASI scores.
EFFECTS OF VITAMIN D ADMINISTRATION FOR WOUND HEALING IN PATIENTS WITH DIABETIC FOOT ULCERS: EVIDENCE BASED CASE REPORT Badralany, Felianty; Nurul Ratna Mutu Manikam
IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN Vol 6 No 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN)
Publisher : Perhimpunan Dokter Gizi Klinik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54773/ijcnp.v6i1.191

Abstract

Diabetes mellitus can cause microvascular and macrovascular complications. Diabetic foot ulcer is the complications that often occur in DM patients, which is as much as 10%-25%. In Indonesia, the incidence of diabetic foot ulcers is 12% and DM patients can be at risk of diabetic foot ulcers as much as 55.4%. The mortality rate that occurs as a result of diabetic foot ulcers can reach around 15-30%. Patients who have diabetic foot ulcers significantly decreased vitamin D levels. This study aims to determine the effectiveness of vitamin D supplementation for wound healing in diabetic foot ulcers.
Urinary PYD/Creatinine Ratio Has Negative Correlation to Serum 25(OH)D and Positive Correlation to Chronic Lead Exposure Index Hajar, Siti Sarah; Mudjihartini, Ninik; Manikam, Nurul Ratna Mutu; Mulyana, Mulyana; Mansyur, Muchtaruddin
The Indonesian Biomedical Journal Vol 16, No 4 (2024)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v16i4.3174

Abstract

BACKGROUND: The burden of disease due to lead exposure continues to increase. Lead interferes with 25(OH)D hydroxylation and calcium transport, increasing osteoclastic activity and bone resorption. Pyridinoline crosslinks (PYD), as an indicator of bone damage, can be seen earlier compared to imaging changes. Therefore, it is necessary to determine the correlation between serum 25(OH)D levels and the urinary PYD/creatinine ratio in workers exposed to lead, since up to now, there are only limited studies related to it.METHODS: This cross-sectional study involved 104 workers exposed to lead, selected from parents whose children had blood lead levels above 10 µg/dL. Questionnaires and physical examination were performed to obtain characteristic data from subjects. Data regarding blood lead levels, serum 25(OH)D levels, urinary PYD levels, and urinary creatinine levels were also obtained from various laboratory methods.RESULTS: Most subjects (86.5%) had inadequate serum 25(OH)D. Median blood lead levels was 6.3 (1.2-35.5) µg/dL, chronic lead exposure index was 35.3 (1.2-535.8) years µg/dL, serum 25(OH)D levels was 22 (8-52) ng/mL, and urinary PYD/creatinine ratio was 5.3 (3.6-28.1)×10-6. There was a significant negative correlation between serum 25(OH)D levels and urinary PYD/creatinine ratio in workers exposed to lead. There was also a significant positive correlation between chronic lead exposure index and the urinary PYD/creatinine ratio.CONCLUSION: Since urinary PYD/creatinine ratio is correlated with serum chronic lead exposure index and serum 25(OH)D levels, it suggests that pyridinoline might be a potential biomarker to detect bone metabolism disorder due to the chronic lead exposure. Vitamin D adequacy is also an important factor in preventing bone metabolism disorder amidst chronic lead exposure.KEYWORDS: 25(OH)D, bone resorption, pyridinoline, lead, worker
Co-Authors Adianto Nugroho Adityo Wibowo Akhmad Noviandi Syarif Amelia Jessica Anindhita, Bintari Astutik, Erni Badralany, Felianty Basalamah, Tarafainy Bintari Anindhita Budi Rahayu Diana Sunardi Dita Aditianingsih Dwirini Retno Gunarti Enny Probosari Fadilla, Chusnul Farapti Farapti Fariz, Nurwidya Fattrias Handayani Jayaatmaja Fiastuti Witjaksono Godong, Bernardine Hajar, Siti Sarah Heri Nugroho Hertanto Wahyu Subagio Hidayat, Astriliana Febrianawati Inge Permadhi K.N, Beta Novianti Katya Saphira Kirana, Annisa Nurul Krisadelfa Sutanto Krisadelfa Sutanto Lily Indriani Octovia Luciana B Sutanto Marcia Kumala Marvin Marino Meilianawati Meilianawati Metta Satyani Muchtaruddin Mansyur Mulyana Mulyana Nandita Melati Putri Neni Sawitri Ninik Mudjihartini Oentiono, Oki Yonatan Oki Yonatan Oentiono Puspasari, Devi Rasyid, Nurhayati M Rizka Hanifa Singal, Anna Maurina Tri Indah Winarni Wahyu Ika Wardhani Wahyu Ika Wardhani Wardhana, Aditya Wiji Lestari Wina Sinaga Yohannessa Wulandari