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All Journal HAYATI Journal of Biosciences Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Global Medical and Health Communication Jurnal Sumberdaya Hayati Paediatrica Indonesiana Acta Biochimica Indonesiana Majalah Kedokteran Andalas Medika Kartika : Jurnal Kedokteran dan Kesehatan World Nutrition Journal Science Midwifery Jurnal Darma Agung JOURNAL LA MEDIHEALTICO Pharmaceutical And Biomedical Sciences Journal (PBSJ) Archives of Pediatric Gastroenterology, Hepatology, and Nutrition Molekul: Jurnal Ilmiah Kimia
Dwirini Retno Gunarti
Departemen Biokimia Dan Biologi Molekuler Fakultas Kedokteran Universitas Indonesia, Jl. Salemba Raya 6 Jakarta
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Journal : paediatrica indonesiana

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Morphology and disaccharidase activity of small intes- tinal mucosa in post-weaning-induced malnourished rats and after realimentation Rustadi Sosrosumihardjo; Agus Firmansyah; Asri Rasad; Daldiyono Harjodisastro; Endi Ridwan; Septilia Inawati Wanandi; Dwirini Retno
Paediatrica Indonesiana Vol 46 No 5 (2006): September 2006
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (403.995 KB) | DOI: 10.14238/pi46.5.2006.229-35

Abstract

Background The most common cause of failure to thrive in in-fants is malnutrition which causes histological and biochemicalchanges of small intestine. Studies on histology and enzyme ac-tivity of small intestinal mucosa were not much developed.Objective To study about histology and disaccharidases activity ofsmall intestinal mucosa in post-weaning-induced malnourished rats.Methods We used Sprague-Dawley white rats as the subjects ofthis study with post test-control group design. The study was per-formed at the CentER for Research of Food and Nutrition Devel-opment from April 2003 to December 2004.Results There were a decrease of body weight (hypotrophy nor-moblastic) and an increase of disaccharidase activity of small in-testinal mucosa in post-weaning-induced malnourished rats. Afterrealimentation, there were an increase of body weight, an improve-ment of the hypotrophy, and a decrease of the enzyme but theystill cannot reach normal condition.Conclusion In malnourished rats, there are decrease of bodyweight hypotrophy normoblastic and increase of disaccharidasesactivity of intestinal mucosa that are improved after realimentation
Co-Authors Agus Firmansyah Agus Firmansyah Andayani, Diyah Eka Annisa Rahmah Furqaani Asri Rasad Asri Rasad Badrya, Leily CHRIS ADHIYANTO Daldiyono Harjodisastro Ella Amalia, Ella Endi Ridwan Endi Ridwan Gantini, Ria Syafitri Evi HANIFAH RAHMI Hermansyah Hermansyah Hermansyah Katya Saphira Laifa Annisa Hendarmin Lusinanto, Arfat Mayasari, Citra Krisna Medina Athiah Mike Permata Sari Mohamad Sadikin MOHAMAD SADIKIN Mohamad Sadikin Mohamad Sadikin Muhammad Irsan Saleh Noor Diah Erlinawati Nugraha, Yudhi Nurul Ratna Mutu Manikam Octovia, Lily Indriani Rahmanita, Hania Asmarani Rustadi Sosrosumihardjo Rustadi Sosrosumihardjo Safyudin Saleh, Mgs. M. Irsan Samuel Oetoro Saputro, Alvreyna Cherienda Laviashna Septilia I. Wanandi Septilia Inawati Wanandi Sri Redjeki Subandrate Suri, Auliyani Andam Suwarsono, Erike A. Suwarsono A Wardani, Putri Kusuma Wulandari, Yohannessa Yudianita Kesuma, Yudianita Zen Hafy Zeti Harriyati