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All Journal E-Jurnal Medika Udayana BioWallacea Journal of Biological Research Jurnal Ilmu Kesehatan Jurnal Ilmu dan Teknologi Kesehatan INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Bantenese Jurnal Pengabdian Masyarakat Jurnal Ilmiah Kesehatan Ar-Rum Salatiga Journal of Nursing and Health (JNH) Akper Yakpermas Banyumas Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Gema Lingkungan Kesehatan Lansau: Jurnal Ilmu Kefarmasian Jurnal Abdi dan Dedikasi kepada Masyarakat Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Analis Kesehatan Kendari
Firdayanti Firdayanti
Politeknik Bina Husada Kendari
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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PROFIL KOLESTEROL TOTAL PADA PENDERITA PENYAKIT JANTUNG KORONER DI RUMAH SAKIT UMUM DAERAH KOTA KENDARI Ani Umar; firdayanti firdayanti; Nur Hijreah Samsu
Jurnal Analis Kesehatan Kendari Vol. 5 No. 1 (2022): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 5 (1) Desember 2022)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v5i1.215

Abstract

Total Cholesterol profile in patients with coronary heart disease at the city general hospital in kendari”. Coronary heart disease is one of the three main causes of death in the world each years. PJK is a disease that arises due to narrowing or blockage of arteries that enter the bloodstream to the heart muscle so that there is a lack of oxygen supply to the heart muscle. Total cholesterol is the total amount of cholesterol in the blood. Examination of total cholesterol which is a blood test that functions to determine total cholesterol levels in patients with coronary heart disease. The purpose of this study was to determine the total cholesterol profile in patients with coronary heart disease in the general hospital area of the city of kendari with enzymatic kinetic methods. Samples of patients with coronary heart disease as many as 18 samples with sampling techniques namely accidental sampling. Based on the research that has been done obtained results that there are 5 people (27%) have level ≥ 200 mg/dL shows an increase in total cholesterol levels and 13 people (72%) have level ≤ 200 mg/dL showing normal cholesterol levels. Key Words : Coronary Heart Disease, Total Cholesterol, Examination of Total Cholesterol.
PROFIL UREUM DAN KREATININ SERUM SEBAGAI INDIKATOR DISFUNGSI GINJAL PADA PENDERITA HIV YANG MENDAPAT TERAPI ANTIRETROVIRAL Susanti Susanti; Sri Aprilianti Idris; Firdayanti Firdayanti
Jurnal Ilmiah Kesehatan Ar-Rum Salatiga Vol 9, No 2 (2025)
Publisher : STIKES Ar-Rum Salatiga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36409/jika.v9i2.263

Abstract

Human Immunodeviciency Virus (HIV) merupakan Retrovirus golongan RNA yang menyerang kekebalan tubuh manusia. Penderita HIV harus memakai obat ARV seumur hidup yang untuk mencegah replikasi virus HIV di dalam tubuh. Efek samping dari penggunaan obat Antiretroviral terjadi toksisitas yang akan menyebabkan terganggunya fungsi ginjal yang ditandai oleh suatu kondisi yang memicu infeksi neoplasma sekunder, dan manifestasi neurologis dari kadar ureum. Penelitian ini dilaksanakan di Laboratorium Kimia Klinik Analis Kesehatan Politeknik Bina Husada Kendari pada bulan April 2019. Tujuan dari penelitian ini adalah untuk mengetahui profil ureum dan kreatinin serum sebagai indikator disfungsi ginjal pada penderita HIV yang mendapat terapi antiretroviral. Jenis Penelitian yang digunakan adalah deskriptif analitik dengan metode pengambilan sampel cross sectional study untuk melakukan pemeriksaan kadar ureum dan kreatinin pada 20 sampel darah penderita HIV/AIDS dengan menggunakan tekhnik pengambilan sampel total sampling serta dianalisis secara statistik menggunakan uji regresi linear sederhana. Hasil penelitian menunjukkan hasil analisis secara statistik menggunakan regresi linear sederhana menunjukkan bahwa nilai yang signifikan p=0,684 (p>0,05) artinya tidak terdapat hubungan antara lama penggunaan obat ART dengan kadar ureum dan kreatinin pada penderita HIV.
Platelet to cholesterol ratio of high density lipoprotein cholesterol is associated with diabetes and comorbidity risk Ani Umar; Firdayanti; Heni Umar; Angriani Fusvita; Susanti; Sri Aprilianti Idris
Gema Lingkungan Kesehatan Vol. 24 No. 2 (2026): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v24i2.452

Abstract

This study aims to analyze the relationship between platelet to HDL cholesterol (Platelet to HDL Ratio / PHR) ratio and the presence of type 2 diabetes mellitus, as well as evaluate the ability of PHR as a predictor of comorbidity risk. Multivariate logistic regression analysis was used to estimate the odds ratio (OR) and 95% CI. The discriminatory ability of the model is evaluated with the receiver operating characteristic curve (ROC), with the area under the curve (AUC) used to measure the model's performance. Sensitivity and specificity. This study used a cross-sectional observational design with 220 participants (110 type 2 diabetes patients and 110 non-diabetic controls) from the Southeast Sulawesi Provincial General Hospital. Samples were selected based on inclusion criteria (age 30–70 years, for the diabetes group) and exclusion (such as anemia or use of anticoagulant drugs). Data were collected through clinical examinations (age, BMI, blood pressure, platelet count, HDL). PHR is calculated as the number of platelets (per μL) divided by HDL levels (mg/dL). Statistical analysis was performed using independent t-test, multivariate logistic regression, and ROC curve with SPSS software (p < 0.05). The results showed that PHR was significantly higher in the diabetes group with comorbidities (mean 5.49±2.10) than in healthy individuals (4.25±2.39; p < 0.001). The ROC curve shows an AUC of 0.70 for PHR in predicting comorbidity risk, better than HDL alone (AUC 0.55). This study shows that platelet-to-HDL ratio (PHR) is proven to be a simple and economical potential biomarker for detecting an association with diabetes and predicting the risk of vascular comorbidities. These findings support the use of PHR in routine clinical practice, especially in developing countries such as Indonesia. This research contributes to the strategy for the early prevention of diabetes complications through easily accessible hematological parameters.
Gambaran Kalsium Urin pada Lanjut Usia Warga Tobuha Kecamatan Puuwatu Kota Kendari Muhamma Sultanul Aulya; Siti kaylah; Sri Aprilianti Idris; Firdayanti; Ani Umar
coba Vol 14 No 2 (2026): Mei 2026
Publisher : Akademi Keperawatan Dharma Husada Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32831/jik.v14i2.1016

Abstract

Pendahuluan: Kadar kalsium urin yang tinggi dapat disebabkan oleh peningkatan absorpsi kalsium di saluran cerna atau penurunan deposisi kalsium ke dalam tulang. Kondisi tersebut dapat meningkatkan kadar kalsium dalam darah yang selanjutnya diekskresikan melalui urin. Lansia merupakan kelompok yang rentan mengalami perubahan metabolisme kalsium akibat proses penuaan. Penelitian ini bertujuan untuk mengetahui gambaran kadar kalsium urin pada lansia di Jalan Perkuburan, Kecamatan Puuwatu. Metode: Penelitian ini menggunakan desain deskriptif. Sampel penelitian terdiri atas 33 sampel urin lansia yang berdomisili di Jalan Perkuburan, Kecamatan Puuwatu. Pemeriksaan kadar kalsium urin dilakukan secara kualitatif menggunakan metode Sulkowitch melalui reaksi pengendapan kalsium dengan reagen Sulkowitch. Sampel urin dikumpulkan pada pagi hari dan dianalisis sesuai prosedur pemeriksaan. Hasil: Hasil pemeriksaan menunjukkan bahwa dari 33 responden, sebanyak 7 orang (21,2%) memperoleh hasil negatif, sedangkan 26 orang (78,8%) memperoleh hasil positif kalsium urin berdasarkan metode Sulkowitch. Kesimpulan: Sebagian besar lansia di Jalan Perkuburan, Kecamatan Puuwatu menunjukkan hasil positif kalsium urin berdasarkan pemeriksaan metode Sulkowitch. Temuan ini menunjukkan tingginya proporsi lansia dengan hasil positif kalsium urin sehingga diperlukan penelitian lanjutan menggunakan metode kuantitatif untuk mengukur kadar kalsium urin secara lebih akurat serta mengidentifikasi faktor-faktor yang memengaruhinya. Kata Kunci : Kalsium Urin, Lanjut Usia, Warga Perkuburan.
Assessement of Candida albicans of the oral mucosa among type-2 diabetes mellitus patients attending Bahteramas Hospital, Southeast Sulawesi Province Firdayanti Firdayanti; Angriani Fusvita; Ani Umar
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 7 No 2 (2025): From Natural Compounds to Disease Mechanisms: An Integrated Research Outlook
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v7i2.5496

Abstract

Diabetes Mellitus (DM) is a disease characterized by hyperglycemia resulting from either insulin deficiency or insulin resistance. Candida albicans is a fungus generally found on the surface of the mucous membrane, which usually dominates and overgrows among DM patients. This study aims to identify the presence of the C. albicans fungus on the oral mucosa of individuals with Type-2 Diabetes Mellitus at Bahteramas Hospital, Southeast Sulawesi Province, Indonesia. A descriptive study was employed, and a purposive sampling technique was used to select a sample of 62 patients. Swab samples were cultured on Potato Dextrose Agar medium for Gram staining and carbohydrate assimilation tests. The resulting culture was tested using CHROMagarTM Candida (CAC) media. Among the 62 samples, 56 samples were identified to have a convex colony, a cream-color surface, a smooth texture, and a Gram-positive nature. The carbohydrate assimilation test showed that the indicated samples could ferment glucose and maltose, but not lactose and sucrose. Green colonies are formed through CHROMagarTM Candida differential media testing. There are 56 identification results for C. albicans from oral mucosal swab samples from 62 patients with Type-2 Diabetes Mellitus at the Bahteramas Hospital, Southeast Sulawesi Province, yielding six other patients with negative results.
Co-Authors Andi Arfan Anggraeni Anggraeni Angriani Fusvita Apriyanto Apriyanto Asriullah Jabbar Asriullah Jabbar Aulya, Muhammad Sultanul Balaka, Kemal Idris Bonni Rubak Darmayanita Wenty Elma Winarti Fadhliyah Malik Halik Idris, Sri Aprilianti Irdayanti Irdayanti Linda Faudziah Mentarri Bafadal Mubarak Muhammad Hajrul Malaka Muhammad Ilyas Y Niluh Eka Ayu Pratiwi Nirwati Rusli Nizma Rahmawati Nur Hijreah Samsu Nurhikma Nurmina Nurmina Nurul Afdhaliyah Nurdin Sahidin Sahidin Salmawati Salmawati Sernita Seren Setiawan, Muh. Azdar Siti kaylah Sri Yosin Vinola Suci Devianti Ningsih Susanti Susanti Umar, Ani Umar, Heni Wahyuni Wahyuni