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Guntari Titik Mulyani
Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Hewan Universitas Gadjah Mada
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Education Electrical & Electronics Engineering Energy Engineering Immunology & microbiology Medicine & Pharmacology Social Sciences Veterinary

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Journal : Jurnal Veteriner

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Pembelian Ternak dan Kelembaban Tinggi Merupakan Faktor Risiko Leptospirosis pada Sapi di Girimulyo, Kulon Progo, Jogjakarta (PURCHASE OF CATTLE AND HIGH HUMIDITY WERE RISK FACTORS OF BOVINE LEPTOSPIROSIS IN GIRIMULYO, KULON PROGO DISTRICT) Guntari Titik Mulyani; Bambang Sumiarto; Yuriati .
Jurnal Veteriner Vol 15 No 2 (2014)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.602 KB)

Abstract

Leptospirosis is an acute infectious disease could to attack humans and animals such as dogs, cats,cows, pigs, and wild animals such as rats, weasels and squirrels. The death rate of human leptospirosis inIndonesia reached 2.5 to 16.5%. Leptospirosis attacked approximately 274 residents, 18 fatalities atKulonprogo disctrict, and designated as Extraordinary Events in 2011. The purpose of this reasearch is todetermine risk factors affecting the prevalence of leptospirosis in cattle in the area of human leptospirosisin Girimulyo, Kulon Progo. This study used 132 samples of cattle blood. Methods of examination withMicro Aglutination Test (MAT) conducted at the Center for Veterinary Research, Bogor. Micro AglutinationTest is done by creating a serum dilution with PBS in stages then added antigen in the form of various cultures leptospira serovar. Subsequently incubated at 28-30 ° C for 2 hours, and was reading the resultsunder a microscope dark field / phase contrast. Endpoint reading was 50% agglutination, highest finalserum dilution in serum-antigen mixtures that showed 50% agglutination is called the titer. Serum witha titer of 1:100 or more against one or more tested positive for serovar. Micro Aglutination Test result wasthe dependent variable (Y), while the independent variables (X) were factors of farmers, animal factors,enclosure factors, and feed factors. Univariate analysis was done to see descriptively each variable studied.Association between the prevalence of leptospirosis and risk factors was analyzed by Chi Square.Multivariate Logistic Regression Analysis was used to build models of leptospirosis disease to investigatethe risk factors associated with leptospirosis. Variables that influence the prevalence of leptospirosiswere measured magnitude of association by Odd Ratio. The results of study that the prevalence of bovineleptospirosis in Girimulyo subdistrict, Kulonprogo district was 7.6%. Risk factors for the prevalence ofleptospirosis in cattle in Girimulyo subdistrict, Kulonprogo district were livestock purchased factor (OR5.49) and a high humidity factor (OR 1.65). These results can be concluded that leptospirosis infection incattle is high (7.6%) in the area of human leptospirosis. The possibility cattle as a source of infection inhumans still needs further research.
Leptospirosis pada Kucing di Yogyakarta dan Sekitarnya (FELINE LEPTOSPIROSIS IN YOGYAKARTA AND ITS SURRONDING) Guntari Titik Mulyani; Slamet Raharjo; Agung Budi Purnomo; Yuli Santoso; Kurnia Kurnia; Dyah Kunti Wirapratiwi
Jurnal Veteriner Vol 19 No 4 (2018)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (84.737 KB) | DOI: 10.19087/jveteriner.2018.19.4.446

Abstract

Leptospirosis is a zoonotic disease that infects almost of mammals. The infecting microorganism is the Leptospira interrogans, which have many serovars. Clinical leptospirosis is rare in cats, but cats may shed leptospire in the urine to other animals, humans or environment. The aims of this research is to study feline leptospirosis in Yogyakarta and its surrounding. A total of 27 cats consisting of 3 groups of cats: household cats, stray cats, and cats with leptospirosis symptom were used in this research. The blood from all cats were taken 3 ml from cephalica vein, the serum were separated for Microscopic Agglutination Test (MAT). The examination were conducted in Bbalitvet Bogor for 14 Leptospira serovar: Ichterohaemorrhagiae, Javanica, Celledoni, Ballum, Pyogenes, Cynopeteri, Rachmati, Australis, Pomona, Canicola, Grippotyphosa, Bataviae, Hardjo, dan Tarrasovi. The results showed that 1 stray cat was positive for Tarrasovi serovar. From the results of this study can be concluded that there was subclinic feline leptospirosis in Yogyakarta that caused by Leptospira interrogans Tarrasovi serovar.
Kejadian Leptospirosis pada Anjing di Daerah Istimewa Yogyakarta (CASE OF CANINE LEPTOSPIROSIS IN THE CITY OF YOGYAKARTA) Guntari Titik Mulyani; Sri Hartati; Yuli Santoso; Kurnia Kurnia; Agung Budi Pramono; Dyah Kunti Wirapratiwi
Jurnal Veteriner Vol 18 No 3 (2017)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (85.099 KB) | DOI: 10.19087/jveteriner.2017.18.3.403

Abstract

Leptospirosis is a zoonotic disease, which is caused by Leptospira interrogans. The incidence of leptospirosis in dogs varies according to region and season, and is considered as emerging infectious diseases in humans. Clinical symptoms of leptospirosis in dogs vary greatly, some dogs are asymptomatic, with mild symptoms, and others progress to severe illness until death. The study aims to determine cases of canine leptospirosis in Yogyakarta, and identify the serovar that infect them. A total of 20 dogs without symptoms, with mild symptoms, to severe symptoms of leptospirosis were collected their serum and further tested using Microscopic Agglutination Test (MAT) conducted at the Center for Veterinary Research (BBLitvet) Bogor. History of vaccination is recorded as a consideration in interpreting the MAT results. The results showed that three out of the 20 samples were positive leptospirosis. Of the three positive samples, one was identified as serovar bataviae, another one as serovar bataviae and tarrasovi, and the last as serovar bataviae, tarrasovi, ichterohaemorrhagiae, canicola, celledoni, pyrogenes, cynopteri, and rachmati, respectively. The three dogs with leptospirosis showed similar clinical symptoms i.e. Anorexia, lethargy, and fever. It can be concluded that there are cases of canine leptospirosis in Yogyakarta which is predominantly caused by Leptospira interrogans serovar bataviae. ABSTRAK Leptospirosis adalah penyakit zoonosis, yang disebabkan oleh Leptospira interrogans. Kejadian leptospirosis pada anjing bervariasi menurut wilayah dan musim, dan dianggap sebagai penyakit menular yang muncul pada manusia. Gejala klinis leptospirosis pada anjing sangat bervariasi, beberapa anjing tanpa menunjukkan gejala, dengan gejala ringan, dan yang lain melanjut menjadi penyakit yang parah sampai kematian. Penelitian ini bertujuan untuk mengetahui kasus leptospirosis pada anjing di Propinsi Daerah Istimewa Yogyakarta, dan mengidentifikasi serovar yang menginfeksinya. Sebanyak 20 ekor anjing tanpa gejala, dengan gejala ringan, sampai gejala parah leptospirosis diambil serumnya guna pemeriksaan Microscopic Agglutination Test (MAT) yang dilaksanakan di Balai Besar Penelitian Veteriner (BBLitvet), Bogor. Sejarah vaksinasi dicatat sebagai bahan pertimbangan dalam menginterpretasi hasil pemeriksaan MAT. Hasil penelitian menunjukkan bahwa tiga dari 20 sampel positif leptospirosis. Satu sampel positif terhadap serovar Bataviae, satu sampel positif terhadap serovar Bataviae dan Tarrasovi, dan satu sampel lagi positif terhadap serovar Bataviae, Tarrasovi, Ichterohaemorrhagiae, Canicola, Celledoni, Pyrogenes, Cynopteri, dan Rachmati. Anjing yang positif leptospirosis menunjukkan gejala klinis yang sama berupa anoreksia, kelemahan, dan demam. Dari hasil penelitian ini dapat disimpulkan bahwa terdapat kasus leptospirosis pada anjing di Yogyakarta yang penyebabnya dominan oleh Leptospira interrogans serovar Bataviae.
Co-Authors Addin Suwastono, Addin Adhistya Erna Permanasari Agung Budi Pramono Agung Budi Purnomo Agustin Indrawati Aidah Rahmanita Alfarisa Nururrozi Alfarisa Nururrozi, Alfarisa Alfariza Nururozi Ambar Widuri Andriani Dwi Hapsari Angeline Ganapragasam Anis Pramundari Antoni Kirwanto Bambang Sumiarto Bambang Sumiarto Bambang Sumiarto Bambang Sumiarto Dwi Priyowidodo Dyah Kunthi Wirapratiwi Dyah Kunti Wirapratiwi Dyah Kunti Wirapratiwi Eko Sulistyadi Estu Widodo Estu Widodo Estu Widodo, Estu Hary Purnamaningsih Hary Purnamaningsih Haryadi Haryadi Hastari Wuryastuti Hastari Wuryastuti Hastari Wuryastuty Hastari Wuryastuty Hastari Wuryastuty Hastari Wuryastuty Hayu Pradnya Satyaprabha Henricus Roby Cahya Putra Henricus Roby Cahya Putra, Henricus Roby Cahya Ida Tjahajati Irkham Widiyono Juwari J Juwari J, Juwari Kelviano Muqit Kurnia . Kurnia Kurnia Kurnia Kurnia Kurnia Kurnia Laksono Trisnantoro Martathama, Gadis Pramono, Agung Budi Riyandini Putri Satyaprabha, Hayu Pradnya Setyo Budhi Setyo Budhi Setyo Budhi Slamet Raharjo Slamet Raharjo Slamet Raharjo Slamet Raharjo Soedarmanto Indarjulianto Soedarmanto Indarjulianto Soedarmanto Indarjulianto Soedarmanto Indarjulianto Sri Hartati Sri Hartati Sri Hartati Sri Hartati Sri Hartati Sugiwinarsih S Sugiwinarsih S, Sugiwinarsih Teguh Budipitojo Tri Atmojo Tri Untari Wayan Tunas Artama Yanuartono . Yanuartono Yanuartono Yanuartono Yanuartono Yanuartono, Yanuartono Yeo Suan Jiao Yuda Heru Fibrianto Yuda Heru Fibrianto Yuli Santoso Yuli Santoso Yuriadi . Yuriadi Yuriadi Yuriadi Yuriadi Yuriadi Yuriadi, Yuriadi Yuriati .