Claim Missing Document
Check
Articles

Found 23 Documents
Search

PENGARUH PEMBERIAN MANUR BROILER DENGAN FERMENTASI Lactobacillus casei TERHADAP KONVERSI PAKAN AYAM KAMPUNG Nururrozi, Alfarisa; Indarjulianto, Soedarmanto; Ramandani, Dhasia; Yanuartono, Yanuartono
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol 5, No 2 (2018): December 2018
Publisher : Badan Pengkajian dan Penerapan Teknologi (BPPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (995.536 KB) | DOI: 10.29122/jbbi.v5i2.2774

Abstract

The Effect of Broiler Manure with Lactobacillus casei Fermentation on the Kampung Chicken Feed Convertion Ratio ABSTRACTHusbandry of kampung chicken is constrained by high feed prices and poor productivity. This study aims to utilize alternative feed materials derived from broiler manure to obtain a cheaper feed with good quality. Manure contains high nutrients. Manure was fermented using Lactobacillus casei to improve feed conversion. Two hundred chickens were divided into 4 groups (n = 50). Groups P1, P2, and P3 were given 4%, 8%, and 12% fermentation of L. casei, respectively. Group P0 was given a regular feed without L. casei. Each treatment group consisted of four replicates and were maintained for 60 days. The research design used was Completely Randomized Design subjected to analysis of variant (ANOVA) followed by Duncan test. The feed conversion values of groups P0, P1, P2, and P3 were 4.46; 4.38; 4.21; and 4.54, respectively. The results showed that the feed conversion was not significant in all groups. It was concluded that L. casei fermenter could not improve the feed conversion ratio (FCR).Keywords: FCR, fermentation, kampung chicken, Lactobacillus casei, manure ABSTRAKBudidaya ayam kampung terkendala tingginya harga pakan dan rendahnya produktivitas. Penelitian ini bertujuan memanfaatkan pakan alternatif bersumber manur (limbah kotoran) ayam broiler untuk memperoleh pakan murah dengan kualitas baik. Manur broiler masih mengandung nutrisi yang tinggi. Manur difermentasi menggunakan Lactobacillus casei untuk memperbaiki konversi pakan. Dua ratus ekor ayam dibagi menjadi 4 kelompok (n=50 ekor). Kelompok P1, P2, dan P3 masing-masing diberi ransum yang ditambah fermentasi L. casei sebanyak 4%, 8%, dan 12%. Kelompok P0 diberikan pakan biasa tanpa penambahan L. casei. Setiap kelompok perlakuan terdiri dari empat ulangan dipelihara selama 60 hari. Penelitian menggunakan Rancangan Acak Lengkap (RAL) dengan analisis ragam yang dilanjutkan dengan uji Duncan. Konversi pakan dari kelompok P0, P1, P2, dan P3 berturut-turut 4,46; 4,38; 4,21; dan 4,54.  Hasil penelitian menunjukkan konversi pakan tidak berbeda nyata pada semua kelompok perlakuan. Dari hasil penelitian disimpulkan penggunaan fermenter L.casei pada pakan belum mampu memperbaiki konversi pakan.Kata Kunci: ayam kampung, FCR, fermentasi, Lactobacillus casei, manur
MANURE UNGGAS: SUPLEMEN PAKAN ALTERNATIF DAN DAMPAK TERHADAP LINGKUNGAN Yanuartono, Yanuartono; Nururrozi, Alfarisa; Indarjulianto, Soedarmanto; Haribowo, Nurman; Purnamaningsih, Hary; Raharjo, Slamet
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol 5, No 2 (2018): December 2018
Publisher : Badan Pengkajian dan Penerapan Teknologi (BPPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1472.076 KB) | DOI: 10.29122/jbbi.v5i2.2775

Abstract

Manure Poultry: Alternative Feed Supplements and Impacts on the EnvironmentABSTRACTThe increase in protein demand is now of serious concern as the human population is forecasted to rise to as much as 9.6 billion by 2050. The poultry industry is one of the largest and fastest growing sectors of livestock production in the world. Increased production results in increased sewage so that the impact on the emergence of environmental problems associated with increased air pollution, water, and soil. The sustainability of animal feeds is crucial in the development of livestock production systems, and feed efficiency can be improved by reusing poultry waste in livestock diets, thus diminishing the use of feed grains. There are several ways of disposing of poultry waste including burial, incineration, composting, fertilizer or source of biogas energy and feed for livestock. Poultry manure is a rich source of lignocelluloses, polysaccharides, proteins, minerals, and other biological materials. It is currently expected some problems can be overcome by utilizing poultry manure waste as an alternative feed source for livestock. This paper aims to review the negative effects of excessive chicken manure and its benefits as an alternative feed for livestock and fish.Keywords: alternative feed, livestock, pollution, poultry industry, poultry manure ABSTRAKKenaikan permintaan protein menjadi perhatian serius karena populasi manusia diperkirakan akan meningkat menjadi sebanyak 9,6 miliar orang pada tahun 2050. Industri perunggasan merupakan salah satu sektor produksi ternak terbesar dan tercepat di dunia. Meningkatnya hasil produksi tersebut akan menambah jumlah limbah sehingga berdampak pada munculnya masalah lingkungan yang terkait dengan peningkatan polusi udara, air dan tanah. Ketersediaan pakan hewan secara berkesinambungan sangat penting dalam pengembangan sistem produksi ternak dan efisiensi pakan dapat ditingkatkan dengan menggunakan kembali limbah unggas sebagai bahan pakan ternak, sehingga mengurangi penggunaan biji-bijian sebagai sumber pakan. Ada beberapa metode mengurangi jumlah manure ayam termasuk penguburan, insinerasi, pengomposan, pemupukan atau sumber energi biogas dan pakan ternak. Kotoran unggas adalah sumber lignoselulosa, polisakarida, protein, mineral dan bahan biologi lainnya. Saat ini diperkirakan beberapa permasalahan bisa diatasi dengan memanfaatkan limbah manure unggas sebagai sumber pakan alternatif bagi ternak. Tulisan ini bertujuan untuk mengkaji dampak negatif dari manure ayam yang berlebihan dan manfaatnya sebagai pakan alternatif untuk ternak dan ikan.Kata Kunci: industri perunggasan, manure ayam, pakan alternatif, polusi, ternak
Diare Disebabkan Infeksi Escherichia coli pada Anjing Dewandaru, Risang Aji; Indarjulianto, Soedarmanto; Yanuartono, Yanuartono; Nururrozi, Alfarisa; Purnamaningsih, Hary; Hayati, Rusmi
Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veterinary Science) Vol 9 No 2 (2019): Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veter
Publisher : Fakultas Peternakan Universitas Papua

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (401.402 KB) | DOI: 10.30862/jipvet.v9i2.22

Abstract

Diarrhea is a symptom of a disease that often occurs in dogs, but the diagnosis and therapy usually only based on clinical symptoms. The purpose of this case report is to examine, diagnose and treat a dog with diarrhea. The material of this report is a 4 moths old of female mixbreed dog. The dog examinated including physical, faecal and profile blood examination. Examination of faecal samples includes gastrointestinal parasitic and bacteria identifications. The results of the anamnese and physical examination was found that the dog did not has appetite, vomited, weak, bloody diarrhea and body temperature 40.1℃. The results of faecal examinationcould be isolated Escherichia coli which was sensitive to ampicillin, and blood examination showed neutrophilia and lymphocytopenia. The dog was diagnosed suffered diahrrea caused by E. coli and was treated intra-muscularly for 5 days with 5 mg/kg body weight of ampicillin, twice a day, and 1 time 1 ml vitamin K and 0.37 ml vitamin B-complex. The results of the therapy showed a development of healing gradually and the dog was declared cured on the 7th day of treatment.
Myiasis pada Ruminansia: Diagnosis, Manajemen Terapi dan Pencegahan Kaswardjono, Yanuartono; Indarjulianto, Soedarmanto; Nururrozi, Alfarisa; Purnamaningsih, Hary
Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veterinary Science) Vol 9 No 2 (2019): Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veter
Publisher : Fakultas Peternakan Universitas Papua

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (462.428 KB) | DOI: 10.30862/jipvet.v9i2.64

Abstract

Myiasis is defined as a condition in which maggots are from certain fly species that utilize living, dead, or necrotic tissue from the host as a feed source for their growth and development and attack all types of vertebrate animals that are warm-blooded including humans. myiasis is often found in domestic animals in tropical regions throughout the world, especially in developing countries such as Indonesia and is generally associated with low levels of welfare of farmers. The diagnosis of myiasis is based on a clinical examination of wound bleeding, fever, a characteristic odor, the discovery of exudates and maggots in the wound. Myiasis treatment is generally local followed by manual removal of larvae and necrotic tissue debris. Systemic treatment usually uses broad-spectrum antibiotics especially when secondary infections occur. Disease prevention can be done by providing information to farmers to pay attention to and carry out livestock sanitation, pens, the surrounding environment and control flies using various methods. Keywords: clinical examination, disease prevention, maggot, myiasis
Laporan Kasus: Penanganan Enteritis pada Kambing Peranakan Ettawa Akibat Nematodiasis dan Koksidiosis Fangidae, Petra Yudha; Nururrozi, Alfarisa; Yanuartono, Yanuartono; Indarjulianto, Soedarmanto
Indonesia Medicus Veterinus Vol 8 (2) 2019
Publisher : Faculty of Veterinary Medicine, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1444.818 KB)

Abstract

Nematodiasis dan koksidiosis merupakan penyakit pada kambing yang dapat menimbulkan kerugian ekonomi yang besar bagi peternak. Seekor kambing Peranakan Ettawa (PE) betina berumur 1 tahun dan berat badan 35 kg, dianamnesis mengalami diare, lemas, dan nafsu makan menurun. Hasil pemeriksaan fisik didapatkan rambut yang kasar, konjungtiva dan gingiva hiperemis, limfaglandula mandibularis dekster bengkak, pada hidung terdapat leleran mukopurulen, peristaltik usus meningkat, dan konsistensi feses yang lembek. Hasil pemeriksaan sampel feses ditemukan adanya ookista Eimeria spp., larva nematoda jenis strongyle dan telur cacing strongyle. Pemeriksaan hematologi didapatkan polisitemia, anemia mikrositik-hipokromik, leukositosis dengan disertai neutrofilia dan eosinofilia. Berdasarkan anamnesis, gejala klinis, pemeriksaan fisik dan laboratorium maka kambing didiagnosis mengalami enteritis akibat nematodiasis dan koksidiosis dengan prognosis fausta. Pengobatan yang diberikan adalah Albendazole 8,5 mg/kg BB (PO), Oxytetracycline 17 mg/kg BB (IM), Diphenhydramine HCL 1 mg/kg BB (IM), dan injeksi multivitamin 3 mL (IM). Tujuh hari setelah pengobatan telah ada perbaikan klinis berupa keadaan kambing yang sudah aktif, tidak diare, feses yang mulai padat, jumlah larva nematoda dalam feses sudah berkurang.
PENGARUH PEMBERIAN MANUR BROILER DENGAN FERMENTASI Lactobacillus casei TERHADAP KONVERSI PAKAN AYAM KAMPUNG Nururrozi, Alfarisa; Indarjulianto, Soedarmanto; Ramandani, Dhasia; Yanuartono, Yanuartono
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 5 No. 2 (2018): December 2018
Publisher : Balai Bioteknologi, Badan Pengkajian dan Penerapan Teknologi (BPPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (995.536 KB) | DOI: 10.29122/jbbi.v5i2.2774

Abstract

The Effect of Broiler Manure with Lactobacillus casei Fermentation on the Kampung Chicken Feed Convertion Ratio ABSTRACTHusbandry of kampung chicken is constrained by high feed prices and poor productivity. This study aims to utilize alternative feed materials derived from broiler manure to obtain a cheaper feed with good quality. Manure contains high nutrients. Manure was fermented using Lactobacillus casei to improve feed conversion. Two hundred chickens were divided into 4 groups (n = 50). Groups P1, P2, and P3 were given 4%, 8%, and 12% fermentation of L. casei, respectively. Group P0 was given a regular feed without L. casei. Each treatment group consisted of four replicates and were maintained for 60 days. The research design used was Completely Randomized Design subjected to analysis of variant (ANOVA) followed by Duncan test. The feed conversion values of groups P0, P1, P2, and P3 were 4.46; 4.38; 4.21; and 4.54, respectively. The results showed that the feed conversion was not significant in all groups. It was concluded that L. casei fermenter could not improve the feed conversion ratio (FCR).Keywords: FCR, fermentation, kampung chicken, Lactobacillus casei, manure ABSTRAKBudidaya ayam kampung terkendala tingginya harga pakan dan rendahnya produktivitas. Penelitian ini bertujuan memanfaatkan pakan alternatif bersumber manur (limbah kotoran) ayam broiler untuk memperoleh pakan murah dengan kualitas baik. Manur broiler masih mengandung nutrisi yang tinggi. Manur difermentasi menggunakan Lactobacillus casei untuk memperbaiki konversi pakan. Dua ratus ekor ayam dibagi menjadi 4 kelompok (n=50 ekor). Kelompok P1, P2, dan P3 masing-masing diberi ransum yang ditambah fermentasi L. casei sebanyak 4%, 8%, dan 12%. Kelompok P0 diberikan pakan biasa tanpa penambahan L. casei. Setiap kelompok perlakuan terdiri dari empat ulangan dipelihara selama 60 hari. Penelitian menggunakan Rancangan Acak Lengkap (RAL) dengan analisis ragam yang dilanjutkan dengan uji Duncan. Konversi pakan dari kelompok P0, P1, P2, dan P3 berturut-turut 4,46; 4,38; 4,21; dan 4,54.  Hasil penelitian menunjukkan konversi pakan tidak berbeda nyata pada semua kelompok perlakuan. Dari hasil penelitian disimpulkan penggunaan fermenter L.casei pada pakan belum mampu memperbaiki konversi pakan.Kata Kunci: ayam kampung, FCR, fermentasi, Lactobacillus casei, manur
PENENTUAN JENIS KELAMIN BURUNG KENARI (Serinus canaria) BERDASARKAN GEN Chromodomain Helicase DNA-Binding 1 (CHD1) Akhrom, Afif Muhammad; Soedarmanto, Indarjulianto; Yanuartono, Yanuartono; Susmiati, Trini; Nururrozi, Alfarisa; Raharjo, Slamet
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 7 No. 1 (2020): June 2020
Publisher : Balai Bioteknologi, Badan Pengkajian dan Penerapan Teknologi (BPPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (138.004 KB) | DOI: 10.29122/jbbi.v7i1.3178

Abstract

Phenotype determination of sex in young canaries is very low in accuracy. This study aimed to develop a genotypic sexing method in canaries. This study used 12 canaries consisting of 3 mature males, 3 mature females and 6 one-month-old canaries. Phenotypic sexing by cloacal observation was done on all birds, continued by genotypic sexing to identification CHD1 gene using polymerase chain reaction (PCR). The PCR used blood samples for mature canaries, and feather for mature and one-month-old canaries. The results of phenotypic observations showed that all mature male canaries had prominent and pointed cloaca forms, all mature females had flat and wide, whereas all one-month-old birds had a flat cloaca. The result of PCR showed a single band (500 bp) for mature male and double bands (500 bp and 300 bp) for mature female canaries. The PCR results of one-month-old canaries showed that there were one male and five females. Based on this study, it was concluded that genotypic sexing using the PCR method is effective in the sex determination of canaries.Keywords: canary, CHD1, genotype, PCR, sexing ABSTRAKPenentuan jenis kelamin burung kenari muda secara fenotip akurasinya sangat rendah. Penelitian ini bertujuan untuk menentukan jenis kelamin burung kenari secara genotip. Penelitian ini menggunakan 12 ekor burung kenari, terdiri dari 6 ekor dewasa (3 jantan, 3 betina) serta 6 ekor umur 1 bulan. Semua burung ditentukan jenis kelaminnya dengan mengamati kloaka dan identifikasi gen CHD1 menggunakan teknik polymerase chain reaction (PCR). Sampel DNA berasal dari darah dan bulu untuk burung dewasa serta bulu untuk burung umur 1 bulan. Pengamatan fenotip menunjukkan bahwa burung kenari dewasa jantan mempunyai bentuk kloaka menonjol dan runcing, dewasa betina berbentuk datar dan lebar, sedangkan semua burung umur 1 bulan mempunya bentuk kloaka datar. Hasil identifikasi gen CHD1 diperoleh adanya 1 pita gen sekitar 500 bp dari sampel darah dan bulu semua burung kenari dewasa jantan, dan 2 pita gen sekitar 500 bp dan 300 bp dari sampel semua burung kenari betina dewasa. Hasil PCR pada sampel burung umur 1 bulan menunjukkan bahwa 1 ekor jantan dan 5 ekor betina. Berdasarkan penelitian ini dapat disimpulkan bahwa penentuan jenis kelamin secara genotip menggunakan gen CHD1 dapat dilakukan pada burung kenari.
MANURE UNGGAS: SUPLEMEN PAKAN ALTERNATIF DAN DAMPAK TERHADAP LINGKUNGAN Yanuartono, Yanuartono; Nururrozi, Alfarisa; Indarjulianto, Soedarmanto; Haribowo, Nurman; Purnamaningsih, Hary; Raharjo, Slamet
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 5 No. 2 (2018): December 2018
Publisher : Balai Bioteknologi, Badan Pengkajian dan Penerapan Teknologi (BPPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1472.076 KB) | DOI: 10.29122/jbbi.v5i2.2775

Abstract

Manure Poultry: Alternative Feed Supplements and Impacts on the EnvironmentABSTRACTThe increase in protein demand is now of serious concern as the human population is forecasted to rise to as much as 9.6 billion by 2050. The poultry industry is one of the largest and fastest growing sectors of livestock production in the world. Increased production results in increased sewage so that the impact on the emergence of environmental problems associated with increased air pollution, water, and soil. The sustainability of animal feeds is crucial in the development of livestock production systems, and feed efficiency can be improved by reusing poultry waste in livestock diets, thus diminishing the use of feed grains. There are several ways of disposing of poultry waste including burial, incineration, composting, fertilizer or source of biogas energy and feed for livestock. Poultry manure is a rich source of lignocelluloses, polysaccharides, proteins, minerals, and other biological materials. It is currently expected some problems can be overcome by utilizing poultry manure waste as an alternative feed source for livestock. This paper aims to review the negative effects of excessive chicken manure and its benefits as an alternative feed for livestock and fish.Keywords: alternative feed, livestock, pollution, poultry industry, poultry manure ABSTRAKKenaikan permintaan protein menjadi perhatian serius karena populasi manusia diperkirakan akan meningkat menjadi sebanyak 9,6 miliar orang pada tahun 2050. Industri perunggasan merupakan salah satu sektor produksi ternak terbesar dan tercepat di dunia. Meningkatnya hasil produksi tersebut akan menambah jumlah limbah sehingga berdampak pada munculnya masalah lingkungan yang terkait dengan peningkatan polusi udara, air dan tanah. Ketersediaan pakan hewan secara berkesinambungan sangat penting dalam pengembangan sistem produksi ternak dan efisiensi pakan dapat ditingkatkan dengan menggunakan kembali limbah unggas sebagai bahan pakan ternak, sehingga mengurangi penggunaan biji-bijian sebagai sumber pakan. Ada beberapa metode mengurangi jumlah manure ayam termasuk penguburan, insinerasi, pengomposan, pemupukan atau sumber energi biogas dan pakan ternak. Kotoran unggas adalah sumber lignoselulosa, polisakarida, protein, mineral dan bahan biologi lainnya. Saat ini diperkirakan beberapa permasalahan bisa diatasi dengan memanfaatkan limbah manure unggas sebagai sumber pakan alternatif bagi ternak. Tulisan ini bertujuan untuk mengkaji dampak negatif dari manure ayam yang berlebihan dan manfaatnya sebagai pakan alternatif untuk ternak dan ikan.Kata Kunci: industri perunggasan, manure ayam, pakan alternatif, polusi, ternak
Keracunan Parasetamol Pada Kucing Dan Anjing: Gejala Klinis dan Terapi Yanuartono, Yanuartono; Nururrozi, Alfarisa; Indarjulianto, Soedarmanto; Raharjo, Slamet; Purnamaningsih, Hary; Haribowo, Nurman
Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veterinary Science) Vol 10 No 1 (2020): Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Vete
Publisher : Fakultas Peternakan Universitas Papua

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (396.191 KB) | DOI: 10.46549/jipvet.v10i1.86

Abstract

Acetaminophen, commonly known as paracetamol, is a non-steroidal anti-inflammatory drug commonly used in human medicine for its antipyretic and analgesic action. As paracetamol became readily available in many over-the-counter and no-prescription products, reports of paracetamol poisoning in dogs and cats became more common. The toxicity of paracetamol is more pronounced in cats when compared to dogs. Clinical signs of paracetamol toxicity include depression, weakness, tachypnea, dyspnea, vomiting, hypothermia, facial or paw edema, hepatic necrosis, and death. The characteristics of severe paracetamol poisoning are methemoglobinemia, cyanosis, anemia, and jaundice. Although there are no specific antidotes, acetylcysteine is the drug of choice for paracetamol poisoning treatment. Symptomatic and supportive therapies play a more definitive role in the management of paracetamol poisoning. This paper aims to briefly review the clinical symptoms, diagnosis, and treatment of paracetamol poisoning in dogs and cats.
Potensi Bentonite Clay Dan Karbon Aktif Sebagai Aflatoksin Binders Berdasarkan Gambaran Imunologis Dan Histopatologis Pada Ayam Buras Ramandani, Dhasia; Ummami, Risa; Hidayah, Nurulia; Dalimunthe, Naela Wanda Yusria; Indarjulianto, Soedarmanto; Yanuartono, Yanuartono; Nururrozi, Alfarisa
Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veterinary Science) Vol 10 No 1 (2020): Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Vete
Publisher : Fakultas Peternakan Universitas Papua

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (821.995 KB) | DOI: 10.46549/jipvet.v10i1.94

Abstract

Aflatoxin is a toxic compound from the fungus A. flavus which can cause a decrease in chicken productivity. This study aims to evaluate the effect of bentonite clay and activated charcoal in chicken feed as aflatoxin binders based on histopathological and immunological features in chickens. A total of 60 chickens were randomly divided into 4 groups (G0, G1, G2, and G3) each group consisted of 15 chickens. G0 as a control without the addition of aflatoxin to the feed. Groups G1, G2, and G3’s feed were added with 106 ppb of aflatoxin. G2 was treated with 5g/kg bentonite clay, G3 was treated with 5g/kg activated charcoal. Chickens were vaccinated with Newcastle Disease (ND) on day 5. On days 14 and 28 serum was collected from the specimens for titer antibody testing. At the end of the study the chickens were dissected, the liver was taken for a histopathological test. The results of the aflatoxin level in the G0, G1, G2, and G3 groups were 10.5, 106, 19.1, and 23.95 ppb, respectively. Microscopic changes show the negative effects of aflatoxin on the liver organ. Group G0 did not show any histopathological changes, Group G2 and G3 showed several mild histopathological changes, whereas group G1 was the most severe. The antibody titers against Newcastle Disease (ND) of 4-weeks old chickens in G0, G1, G2, and G3 were 64, 4, 32, 32 HI units, respectively. The G0 treatment group has a protective titer against ND disease. Group G1 has the lowest (non-protective) ND antibody titer. Whereas the G2 and G3 groups both have protective titers against ND disease. Based on this study it was concluded that the administration of bentonite clay and activated charcoal was able to produce better immunological and histopathological features than the control group.