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All Journal Buletin Veteriner Udayana Journal of Nutrition College e-Journal Pustaka Kesehatan Journal of Agromedicine and Medical Sciences Majalah Obat Tradisional UNEJ e-Proceeding Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan JURNAL PENDIDIKAN TAMBUSAI Medical and Health Science Journal Buletin Poltanesa Journal of Community Development Journal of Arabic Literature (Jali) Narra J AKSONA CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal Jember Medical Journal (JMJ) International Journal of Health and Information System (IJHIS)
Jauhar Firdaus
Departemen Fisiologi, Fakultas Kedokteran, Universitas Jember
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Environmental Science Health Professions Immunology & microbiology Library & Information Science Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Correlation of Skin Pigmentation Changes as a Side Effect of Clofazimine Treatment with Anxiety Level in MDR-TB Patients at Dr. Soebandi Hospital Sudjarwo, Raisa; Firdaus, Jauhar; Raharjo, Angga
International Journal of Health and Information System Vol. 3 No. 2 (2025): September
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/ijhis.v3i2.57

Abstract

Clofazimine, used to treat Multidrug-resistant tuberculosis (MDR-TB), often causes skin pigmentation changes, potentially impacting patients' self-esteem and anxiety. Anxiety represents a common but often underrecognized comorbidity in MDR-TB patients, who are challenged by lengthy treatment regimens, social stigma, and distressing adverse effects. This study aimed to examine this correlation at Dr. Soebandi Hospital. The study utilized an observational analytic method with a cross-sectional design. The population was all MDR-TB patients in Dr. Soebandi hospital, presented from April to May 2024. We recruited 67 patients using a total sampling technique. We analyzed the primary data from the respondents: 1) Respondents' self-rating of skin pigmentation change; 2) Hamilton Anxiety Rating Scale (HARS) score. We also checked the medical records to analyze the respondents' treatment history. The data were analyzed using the chi-square test. Most respondents were male and in a productive age. The chi-square test results show a p-value of 0.822, indicating no significant correlation between skin pigmentation changes and anxiety levels in MDR-TB patients. Clofazimine-induced skin pigmentation changes had no significant correlation with the anxiety levels among MDR-TB Patients at Dr. Soebandi Hospital. Further studies should consider methodological improvements, including prospective design, larger sample size, mixed method, and involvement of dermatology experts in assessing the skin changes induced by clofazimine. Recognizing individual differences in psychological response highlights the need to offer reassurance, counseling, and psychosocial support for MDR-TB patients.
Tobacco Dust Exposure Among Tobacco Workers in Jember Reduces Lung Function Capacity Nofica, Cheila; Firdaus, Jauhar; Rachmania, Sheilla; Caesarina, Ancah
International Journal of Health and Information System Vol. 3 No. 2 (2025): September
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/ijhis.v3i2.60

Abstract

This study investigated the association between urinary cotinine levels and lung function among tobacco workers in Jember Regency, a major tobacco-producing region in Indonesia. A total of 48 respondents were included based on specific inclusion and exclusion criteria. Urinary cotinine levels were measured using enzyme-linked immunosorbent assay (ELISA), and lung function was assessed via spirometry. Based on FEV1/FVC ratios, 58% of participants exhibited restrictive lung patterns, 29% showed obstructive patterns, and 13% had normal pulmonary function. Statistical analysis conducted using SPSS, with a significance level set at p < 0.05, indicated no statistically significant correlation between urinary cotinine levels and lung function.
Co-Authors Abu Khoiri Achmad Subagio Adelia Handoko Aisya, Meutia Citra Alif Kufari Alyssandra Afqorina Agung Amini, Stefia A. Andi Muhammad, Andi Angela, Patricia Angga Mardro Raharjo Aris Prasetyo Aris Prasetyo Azham Purwandhono Bagus Hermansyah Bagus Satrio Pambudi Bagus Satrio Pambudi, Bagus Satrio Bagus Setia Caesarina, Ancah Cahyana, Nugraha Wahyu Cicih Komariah Dini Agustina Dita Diana Parti El Milla, Kardiana Izza Elly Nurus Sakinah, Elly Nurus ENNY SUSWATI Erma Sulistyaningsih Fambudi, Stela S. Habibbur Rochman Salim Hairrudin Hairrudin Haniefah, Yumna Rifda Heni Fatmawati Ida Srisurani Wiji Astuti Inke Kusumastuti Inreswari, Laksmi Irawan Fajar Kusuma Karim, Muhdie Karisma Adya Pertiwi Komang Dewi Fridayanti Kristianingrum Dian Sofiana Kristianingrum Dian Sofiana Kristianingrum Dian Sofiana Kristianningrum Dian Sofiana Laksmi Indreswari Laksmi Indreswari Lubis, Arinie Awindya Marchianti, Ancah CN. Maria Ulfa Moh. Nur Indra Caesar Muhammad Fakhri Ali Muhammad Rijal Fahrudin Hidayat Ngurah Agung Reza Satria Nugraha Putra Nofica, Cheila Nurud Diniyah Pattipeilohy, Florence Pattipeilohy, Florence Marianty Pipiet Wulandari Pralampita, Pulong Wijang Prasetyo, Aris Putri, Dhiani E. Raharjo, Angga Rumastika, Nindya Shinta Sakinah, Elly N. septa surya wahyudi, septa surya Sheilla Rachmania, Sheilla Sudarmanto, Yohanes Sudjarwo, Raisa Supangat Supangat Supangat Supangat Suryono Suryono T Ariani Widiastini Tartila, Jasmine Tristianti, Farmitalia Nisa Winanda, Leony Agnes Savira Yonas Hadisubroto Yudha Nurdian Yuli Hermansyah Zahrah Febianti