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AIMS65 Scoring System for Predicting Clinical Outcomes Among Emergency Department Patients with Upper Gastrointestinal Bleeding Nabiel, Rifaldy; Munawir, Al; Firdaus, Jauhar
Indonesian Journal of Anesthesiology and Reanimation Vol. 6 No. 1 (2024): Indonesian Journal of Anesthesiology and Reanimation (IJAR)
Publisher : Faculty of Medicine-Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijar.V6I12024.58-72

Abstract

Introduction: Several scoring systems were developed for early risk stratification in Upper Gastrointestinal Bleeding (UGIB) patients. AIMS65 score is a scoring system that only consists of five parameters, it might be used in daily clinical practice because of rapid and easy to calculate within 12 hours of admission. Objective: To evaluate the AIMS65 scoring system as a predictor of mortality, rebleeding events, need for endoscopic therapy, blood transfusion, and ICU admission for all causes of UGIB. Methods: We conducted a systematic review on PubMed, ScienceDirect, ProQuest, and Cochrane Library databases from the 2012 to 2022 publication period. We included either prospective or retrospective cohort studies that reported UGIB with all kinds of aetiologies who presented in the emergency department (ED), reported discriminative performance for each outcome, and reported the optimal cut-off of AIMS65. The primary measurement of discriminative performance for clinical outcomes includes mortality, rebleeding incidents, need for endoscopic therapy, blood transfusion, and ICU admission. Results: We identified 351 published studies, of which 20 were included in this study. Most of the studies reported discriminative performance for predicting mortality, which amounts to about 18 out of 20 studies. Rebleeding prediction was reported in 11 studies, need for endoscopic therapy in 5 studies, blood transfusion in 7 studies, and ICU admission in 2 studies. Most of the studies reported fair to excellent discriminative performance for predicting mortality, but in contrast for predicting rebleeding, the need for endoscopic therapy, blood transfusion, and ICU admission. Cut-off values≥ 2 are frequently reported to distinguish between high-risk and low-risk patients in mortality. Conclusion: AIMS65 can be applied to patients with UGIB in ED for predicting mortality, but not applicable for predicting rebleeding events, the need for endoscopic therapy, blood transfusion, and ICU admission. It enhances early decision-making and triage for UGIB patients.
Cardiac Tamponade in a Chronic Renal Failure Patient with Suspicion of Dialysis Pericarditis: A Case Report Wulandari, Pipiet; Suryono, Suryono; Prasetyo, Aris; Firdaus, Jauhar; Sofiana, Kristianingrum Dian; Indreswari, Laksmi; Handoko, Adelia; Setia, Bagus
International Journal of Health and Information System Vol. 2 No. 1 (2024): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/ijhis.v2i1.39

Abstract

Pericardial effusion is a condition characterized by fluid accumulation in the pericardial cavity. This fluid accumulation can cause disturbances in cardiac contractility, affecting hemodynamic stability. Fluid accumulation is caused by several factors, ranging from the amount of fluid, the speed of fluid accumulation, and the ability of the pericardium to accommodate fluid. One of the causes of pericardial effusion is pericarditis. Pericarditis can be caused by infection and non-infection, such as in patients with chronic renal failure with an incidence of 2-21%, which can lead to cardiac tamponade. In this study, a 46-year-old male patient who came to the emergency room of Dr. Soebandi Hospital, Jember with complaints of shortness of breath in the last 2 months. The patient also complained of heartburn. The patient had a history of chronic renal failure and routinely performed hemodialysis. On examination of vital signs, thoracic photographs, and echocardiography, a picture of cardiac tamponade was found. Cardiac tamponade can occur in patients with chronic renal failure. This is due to the condition of uremia which causes pericarditis. Inflammation of the pericardium causes blood that is intravascular to enter the pericardial cavity, causing fluid accumulation there. If not treated immediately, it can lead to cardiac tamponade which endangers the patient's life.
Uji Aktivitas Antibakteri Senyawa Bawang Putih (Allium Sativum L.) secara In Silico Terhadap Bakteri Streptococcus Pneumoniae Sulihah, Nurfaizah Titisari; Baidowi, Ivan Iqbal; Firdaus, Jauhar; Wulan, Herlina Nur
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 5 No. 3 (2025): Februari
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/comphijournal.v5i3.297

Abstract

Streptococcus pneumoniae is a pathogenic bacterium and one of the leading causes of pneumonia. The first-line therapy for pneumonia typically involves the administration of empirical antibiotics. However, excessive use of antibiotics has triggered resistance to various drugs, highlighting the need for new, potential alternatives with antibacterial activity. In this context, traditional medicinal plants with antibiotic-like properties can be considered, one of which is garlic (Allium sativum L.), known to contain active compounds with antibacterial effects. The objective of this study was to identify the most potent active compound in garlic (Allium sativum) as an antibacterial agent against S. pneumoniae. The method used was an in silico test via molecular docking between garlic’s active compounds and the bacterial target protein, penicillin-binding protein 2 (PBP2). The results showed that the active compounds allicin, ajoene, S-allylcysteine, and alliin have antibacterial potential, with alliin showing the highest potential among them although still lower than the antibiotic benzylpenicillin. This study is based on in silico analysis and therefore requires further experimental validation.
Hubungan Faktor Risiko dan Kondisi Penyakit Penyerta dengan Gambaran Foto Toraks pada Pasien Terkonfirmasi COVID-19 Fatmawati, Heni; Labibah, Zhafirah Rana; Firdaus, Jauhar
Majalah Kedokteran Indonesia Vol 72 No 3 (2022): Journal of the Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.72.3-2022-629

Abstract

Introduction: COVID-19 is a worldwide health problem with a high mortality rate, especially in patients with risk factors. One type of examination to inspect the severity of COVID-19 patients is a chest radiograph. There is a lack of studies on chest radiography features in Indonesia. This study aims to observe the relationship between age, gender, and comorbid conditions with chest radiography features in COVID-19 confirmed.Method: This study was conducted at dr. Soebandi General Hospital uses a cross-sectional design with medical records as the instrument. Chest radiography examination was performed using BSTI classification. Meanwhile, data were analyzed using Chi-Square and contingency coefficient C.Result: The study included 173 patients: 52% were 40-59 years old, 36,4% were 20-39 years old, and 11,6% were ≥ 60 years old; 56,1% were female and 53,9% were male; 50,9% have comorbidities, with hypertension, diabetes, and COPD were the most type of comorbidities. About 48,6% sample had a normal chest radiograph, 27,7% had a mild severity, 17,3% had a moderate severity, and 6,4% had a severe severity. There was a correlation between age and comorbidity with chest radiography features. Otherwise, no correlation was found between sex and chest radiography features.Conclusion: Age and comorbidity were found as significant risk factors for the severity of chest radiograph in COVID-19 with a moderate correlation. However, no correlation was found between sex and chest radiography features.
Analisis Penggunaan Jumlah Bahan Aktif Pestisida dan Banyaknya Keluhan Masalah Kesehatan Pada Petani di Wilayah Agroindustri Jember Sofiana, Kristianningrum Dian; Indreswari, Laksmi; Firdaus, Jauhar; Prasetyo, Aris; Pralampita, Pulong wijang; Supangat, Supangat
Poltanesa Vol 23 No 1 (2022): Juni 2022
Publisher : P3KM Politeknik Pertanian Negeri Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51967/tanesa.v23i1.1209

Abstract

Pestisida dapat menyebabkan masalah kesehatan baik akut ataupun kronik. Latar belakang dari penelitian ini adalah Penggunaan pestisida di kawasan agroindustri Jember yang tidak dapat dihindari.. Paparan pestisida pada petani Jember, baik paparan langsung ataupun tidak langsung, diduga menjadi salah satu penyebab munculnya masalah kesehatan.. Keterkaitan antar penggunaan bahan aktif pestisida dan masalah kesehatan pada petani di wilayah agroindustri jember perlu diteliti. Penelitian ini bertujuan untuk menganalisis penggunaan jumlah bahan aktif pestisida dengan banyaknya masalah kesehatan pada petani di wilayah Agroindustri Jember. Penelitian ini menggunakan metode deskriptif observational dengan pendekatan cross-sectional. Populasi yang diambil adalah petani yang berada di kabupaten jember yang diwakili oleh 11 kecamatan. Besar sampel berjumlah 84 orang yang diambil dengan accidental sampling. Variabel yang diambil adalah jenis pestisida, jumlah bahan aktif yang dipakai, keluhan masalah kesehatan, Analisis menggunakan analisis unvaried dan bivariate menggunakan Chi square tes dengan p <0,05. Penggunaan bahan aktif yang digunakan selama penyemprotan mayoritas 1 bahan aktif 51,19% .Keluhan masalah kesehatan sebesar 52,38% dengan keluhan terbanyak adalah pusing sebesar 29,76%.Hasil Analisis jumlah bahan aktif saat penyemprotan dengan banyaknya keluhan kesehatan dengan menggunakan Chi Square tes, p= 0,009 dengan nilai p<0,05. Dari penelitian ini didapatkan ada hubungan penggunaan bahan aktif residu pestisida dengan keluhan masalah kesehatan pada petani di Jember. Petani yang terpapar kebanyakan tidak merasakan keluhan kesehatan.
Co-Authors Abu Khoiri Achmad Subagio Adelia Handoko Aisya, Meutia Citra Al Munawir Alif Kufari Alyssandra Afqorina Agung Amini, Stefia A. Andi Muhammad, Andi Angela, Patricia Angga Mardro Raharjo Aris Prasetyo Aris Prasetyo Azham Purwandhono Bagus Hermansyah Bagus Satrio Pambudi Bagus Satrio Pambudi, Bagus Satrio Baidowi, Ivan Iqbal Caesarina, Ancah Cahyana, Nugraha Wahyu Cicih Komariah Dini Agustina Dita Diana Parti El Milla, Kardiana Izza Elly Nurus Sakinah, Elly Nurus ENNY SUSWATI Erma Sulistyaningsih Fambudi, Stela S. Habibbur Rochman Salim Hairrudin Hairrudin Handoko, Adelia Haniefah, Yumna Rifda Heni Fatmawati Ida Srisurani Wiji Astuti Inke Kusumastuti Inreswari, Laksmi Irawan Fajar Kusuma Karim, Muhdie Karisma Adya Pertiwi Komang Dewi Fridayanti Kristianingrum Dian Sofiana Kristianingrum Dian Sofiana Kristianningrum Dian Sofiana Labibah, Zhafirah Rana Laksmi Indreswari Lubis, Arinie Awindya Marchianti, Ancah CN. Maria Ulfa Moh. Nur Indra Caesar Muhammad Fakhri Ali Muhammad Rijal Fahrudin Hidayat Nabiel, Rifaldy Ngurah Agung Reza Satria Nugraha Putra Nofica, Cheila Nurud Diniyah Pattipeilohy, Florence Pattipeilohy, Florence Marianty Pipiet Wulandari Pralampita, Pulong Wijang Prasetyo, Aris Putri, Dhiani E. Raharjo, Angga Rumastika, Nindya Shinta Sakinah, Elly N. septa surya wahyudi, septa surya Setia, Bagus Sheilla Rachmania, Sheilla Sofiana, Kristianingrum Dian Sudarmanto, Yohanes Sudjarwo, Raisa sulihah, nurfaizah titisari Supangat Supangat Supangat Supangat Suryono Suryono T Ariani Widiastini Tartila, Jasmine Tristianti, Farmitalia Nisa Winanda, Leony Agnes Savira Wulan, Herlina Nur Yonas Hadisubroto Yudha Nurdian Yuli Hermansyah Zahrah Febianti