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Maternal and Infant Mortality Rates’s Contributing Factors Description and Its Prevention in Kencong Healthcare Center, Jember Regency : A Descriptive Study Parti, Dita Diana; Firdaus, Jauhar; Sakinah, Elly Nurus; Lubis, Arinie Awindya; Pattipeilohy, Florence Marianty
Jurnal Ilmu Kesehatan dan Kesehatan Vol 8 No 01 (2024): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v8i01.4099

Abstract

Background: Maternal Mortality Rates (MMR) and Infant Mortality Rates (IMR) are two of the indicators on the success of health programs in Indonesia. Jember has become the district with the highest rate of maternal and infant deaths throughout 2020-2021. Methods: This research assessed the contributing factors of MMR and IMR in Puskesmas Kencong, Jember Regency. This study uses a qualitative descriptive research design. Data in this study were taken by conducting interviews to fill out questionnaires to mothers who had given birth at least once and the Coordinating Midwife and Head Midwife of PONED (Basic Emergency Neonatal Obstetrics Services) at the Puskesmas Kencong. Then the data from the questionnaires and interviews will be processed and then explained in the narrative. Results:. Based on data from questionnaires filled out by 37 respondents, as well as questions posed to the midwife, Puskesmas Kencong has fulfilled the requirements needed as a PONED Health Center according to PONED Guidelines. Conclusion: The PONED Health Center at Kencong Health Center has a low prevalence of MMR and IMR.
Resistant Starch Tipe 3 Modified Cassava Flour (MOCAF) Sebagai Prebiotik Pada Tikus Model Diabetes Mellitus Firdaus, Jauhar; Sakinah, Elly Nurus
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (587.644 KB) | DOI: 10.19184/jmj.v1i1.149

Abstract

Prebiotik telah dikenal luas memiliki manfaat dalam kesehatan manusia. Sebagai prebiotik alternatif, resistant starch tipe 3 (RS3) memiliki beberapa kelebihan yakni tidak menyebabkan konstipasi maupun diare, RS3 juga menurunkan glukosa darah dan meningkatkan kadar Glucagon Like Peptide-1 (GLP-1) yang memiliki peran utama dalam mekanisme kontrol glukosa darah pada pasien dengan diabetes mellitus (DM). Salah satu bahan yang bisa digunakan sebagai sumber RS3 adalah Modified Cassava Flour (MOCAF). Tujuan dari penelitian ini adalah untuk menganalisis peran RS3 MOCAF sebagai prebiotik alternatif pada tikus diabetes mellitus. Penelitian ini menggunakan hewan coba tikus wistar jantan (Rattus novergicus) model diabetes dengan memberi injeksi streptozotocin (stz) sebanyak 35mg/KgBB secara intraperitoneal. Dilakukan pemeriksaan kadar glukosa darah pada awal penelitian dan setelah induksi stz untuk menentukan kondisi diabetes, dikatakan diabetes jika kadar glukosa darah lebih dari 200mg/dL. Diet RS3 diberikan sebanyak 20 gram/hari selama 4 minggu. Pemberian diet RS3 MOCAF mampu menurunkan kadar glukosa darah puasa dari 494 mg/dL menjadi107 mg/dLdan glukosa darah post prandial dari 526 mg/dL menjadi 96 mg/dL. Analisis mikrobiologi menunjukkan bahwa bakteri yang paling banyak tumbuh pada pemberian diet RS3 MOCAF adalah Lactobacillus Sp. RS3 MOCAF memiliki peran sebagai prebiotik dan mampu menurunkan kadar glukosa darah pada tikus model diabetes melitus.
Lokasi Lesi Sistem Saraf Pusat pada Pemeriksaan Magnetic Resonance Imaging Pasien Covid-19 dengan Stroke: Tinjauan Naratif Moh. Nur Indra Caesar; Muhammad Ihwan Narwanto; Jauhar Firdaus
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (565.169 KB) | DOI: 10.19184/jmj.v1i1.198

Abstract

Stroke dengan infeksi SARS-CoV-2 merupakan komplikasi penyakit yang serius. Fakta menunjukkan bahwa stroke memiliki persentase kematian sebesar 49%, sehingga stroke dengan infeksi SARS-CoV-2 memiliki risiko kematian yang lebih tinggi dengan manifestasi penyakit yang lebih parah. Tujuan dari penelitian ini adalah untuk mengetahui lokasi pemeriksaan lesi pasien stroke dengan COVID-19 menggunakan Magnitude Resonance Imaging (MRI). Metode penelitian yang digunakan adalah penelitian deskriptif analitik dengan menggunakan tinjauan literatur. Sumber data pada penelitian tinjauan literatur ini diambil dari artikel penelitian nasional dan internasional dengan menggunakan basis data PubMed, Science Direct, Cochrane Library, dan Portal Garuda. Hasil dari penelitian ini didapatkan 24 artikel yang memenuhi kriteria inklusi sebagai sampel. Data yang diekstraksi menunjukkan bahwa lokasi anatomi lesi sistem saraf pusat pada pasien stroke dengan infeksi SARS-CoV-2 yaitu pada cerebrum, cerebellum dan ganglia basalis. Lokasi lesi pada otak besar paling sering ditemukan di lobus frontal dan parietal, diikuti oleh lobus temporal. Dari penelitian ini dengan menggunakan metode tinjauan literatur didapatkan gambaran lesi hiperintensitas melalui pemeriksaan MRI dengan berbagai lokasi lesi mulai dari lobus frontalis, parietalis, temporalis, occipitalis, insula, dan basal ganglia, serta cerebellum. Munculnya lesi pada pasien stroke dengan COVID diduga akibat hiperkoagulabilitas yang menyebabkan tromboemboli dan pada pemeriksaan MRI tampak adanya gambaran lesi hiperintensitas.
Differences in Short-term Memory Before and After Exposure to Dangdut Music and Classical Music Angela, Patricia; Firdaus, Jauhar; Parti, Dita Diana
International Journal of Health and Information System Vol. 2 No. 2 (2024): September
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/ijhis.v2i2.37

Abstract

The quality of education in Indonesia is still relatively low when compared with other countries. To improve student achievement, stimulation can be provided to improve learning abilities and memory abilities. The learning and memory process will be optimal if a person is in an alpha brain wave state (8 to 12 Hz). Music that has a tempo of around 60 beats per minute, such as classical music, has the ability to stimulate alpha brain waves. Dangdut music is more familiar to Indonesian people and there is dangdut music which can change alpha brain waves to be more dominant. This type of research is a pre-experimental design with a crossover design. This research aims to see the differences between dangdut and classical music in improving short-term memory. The sampling technique used was purposive sampling with a sample size of 30 people. Short-term memory measurements were carried out before and after receiving music exposure for 30 minutes. Measurements were carried out using the digit span test method. The result was that there was a significant increase in short-term memory after exposure to dangdut and classical music. The conclusion of this research is that dangdut music and classical music both have an impact on improving short-term memory abilities equally well.
Hubungan Tingkat Aktivitas Fisik dengan Tekanan Darah pada Buruh Tani Wanita Hipertensi di Wilayah Kerja Puskesmas Mumbulsari Jember Aisya, Meutia Citra; Jauhar Firdaus; Angga Mardro Raharjo; Aris Prasetyo; Irawan Fajar Kusuma; Ida Srisurani Wiji Astuti
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 5 No. 2 (2024): Oktober
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/comphijournal.v5i2.256

Abstract

Hipertensi pada pekerja pertanian di Indonesia menempati urutan ke-3 teratas berdasarkan Riskesdas, 2018. Tingginya angka tersebut, dipengaruhi oleh banyak faktor, termasuk tingkat aktivitas fisik. Stigma mengenai tingginya aktivitas fisik pada pekerja pertanian sejatinya hanyalah aktivitas kerja, namun tidak untuk aktivitas lainnya, terlebih pekerja wanita yang memiliki peran ganda sehingga tidak ada waktu untuk berolahraga secara rutin. Padahal aktivitas olahraga  dapat mengontrol tekanan darah pada penderita hipertensi. Penelitian ini bertujuan untuk menganalisis ada tidaknya hubungan antara tingkat aktivitas fisik dengan tekanan darah pada buruh tani wanita hipertensi di wilayah kerja Puskesmas Mumbulsari Jember. Penelitian ini merupakan penelitian analitik observasional dengan desain cross-sectional. Sampel penelitian adalah buruh tani wanita hipertensi primer yang tinggal dan pernah melakukan kunjungan di wilayah kerja Puskesmas Mumbulsari Jember. Teknik pengambilan sampel yang digunakan yaitu total sampling sebanyak 42 sampel. Data diambil melalui wawancara kuesioner aktivitas fisik Baecke dan juga pengukuran tekanan darah menggunakan sphygmomanometer digital. Periode sampel yang diteliti adalah buruh tani wanita hipertensi yang melakukan kunjungan ke Posbindu PTM Puskesmas Mumbulsari Jember selama bulan November 2022. Data diolah menggunakan uji statistik regresi linear berganda dengan terlebih dahulu dilakukan uji asumsi klasik. Hasil uji statistik didapatkan  p-value sebesar 0,01 (p<0,05) yang menunjukkan terdapat korelasi signifikan dengan arah negatif antara aktivitas olahraga dengan tekanan darah sistolik pada buruh tani wanita hipertensi di wilayah kerja Puskesmas Mumbulsari Jember.
Exploring the role of polysaccharides in mitigating organ damage caused by pesticide-induced toxicity: A systematic review and meta-analysis of in vivo studies Sakinah, Elly N.; Diniyah, Nurud; Subagio, Achmad; Marchianti, Ancah CN.; Firdaus, Jauhar; Fambudi, Stela S.; Amini, Stefia A.; Putri, Dhiani E.
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1553

Abstract

Although polysaccharides have demonstrated potential in alleviating dysbiosis, the overall impact of polysaccharides on minimizing oxidative stress and organ damage in vivo has not been thoroughly investigated. The aim of this study was to investigate the comprehensive effects of polysaccharides in mitigating pesticide toxicity in animal studies, focusing on biomarkers related to oxidative stress, antioxidant activity, kidney injury, lipid profiles, liver function, and the preservation of liver and kidney weights. A systematic search was conducted across nine indexed databases, including PubMed, Cochrane CENTRAL, Taylor & Francis, Scopus, Sage, EBSCO, ProQuest, ScienceDirect, and Google Scholar. Rayyan.ai was used to screen in vivo studies that met the predefined inclusion and exclusion criteria. The quality of the selected in vivo studies was evaluated using SYRCLE’s Risk of Bias tool, specifically designed for animal studies. Thirteen randomized animal studies, comprising 330 mice and rats, were included in the analysis. The findings revealed that polysaccharides significantly increased antioxidant levels, including catalase (CAT) (p<0.00001), superoxide dismutase (SOD) (p<0.00001), glutathione peroxidase (GPx) (p<0.00001), and reduced glutathione (GSH) (p<0.00001). Polysaccharides also significantly reduced oxidative stress markers, such as malondialdehyde (MDA) (p<0.00001) and nitric oxide (NO) (p<0.0001), as well as kidney injury biomarkers, including serum creatinine (p<0.00001) and urea (p<0.00001). Additionally, improvements in lipid profiles were observed, with significant reductions in triglycerides (TG) (p=0.04) and total cholesterol (TC) (p<0.00001). However, there were no significant differences in high-density lipoprotein (HDL) (p=0.28) and low-density lipoprotein (LDL) (p=0.32) levels. Polysaccharides significantly alleviate liver biomarkers, including aspartate transaminase (AST) (p<0.0001), alanine transaminase (ALT) (p<0.005), and alkaline phosphatase (ALP) (p<0.0001). Polysaccharides also contributed to the maintenance of liver weight (p=0.009), although no significant differences were observed in kidney weights (p=0.81). The study highlights that polysaccharides exert significant effects in enhancing antioxidant levels, reducing oxidative stress and organ damage biomarkers, and preserving liver weights.
Supplementation Of Analog Rice İn Combination With Metformin Prevent Myocardial Cell Death İn Type 2 Diabetuc Rats Muhammad, Andi; Firdaus, Jauhar; Rumastika, Nindya Shinta; Hairrudin, Hairrudin; Sakinah, Elly Nurus
International Journal of Health and Information System Vol. 3 No. 1 (2025): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/ijhis.v3i1.55

Abstract

Type 2 diabetes (T2D) is an urgent health issue that leads to one of the most significant cardiovascular complications worldwide, diabetic cardiomyopathy (DCM), which is associated with high morbidity and mortality. Chronic hyperglycemia and oxidative stress are major contributor for DCM. Analog rice based of MOCAF and corn starch is a functional food recommended as nutritional supplementation to replace staple foods in T2D patients. Analog rice has a high fiber content, high resistant starch and low glycemic index, which can help lower blood sugar levels and prevent DM complications. MOCAF in analog rice is also rich in phenolic compounds, which has potential effect of antioxidant. Metformin is the first line oral therapy for T2D. The present study investigates the potential effects of an analog rice diet in combination with metformin, for the development of DCM. Type 2 diabetic rats were induced by HFD/STZ method and was treated by analog rice and metformin for 4 weeks. Myocardial cell death measured by pyknotic nuclei percentage was analysed. The study result demonstrate that analog rice and metformin prevent the myocardial cell damage observed in type 2 diabetic animals, highlighting analog rice potential as adjuvant therapy, for treating DCM has no clinical significance than metformin therapy alone.
Dirasah Bunyawiyah Jenetikiyah fi al-Syi’ri “Shumtu Min Ajli Ghazah” Li Mahmud Darwis Inda Nadzariyah Lucien Goldman Karim, Muhdie; Firdaus, Jauharotul
Journal of Arabic Literature (JaLi) Vol 2, No 1 (2020): Journal of Arabic Literature (JaLi)
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jali.v2i1.10111

Abstract

AbstractPoetry is a form of expression by a poet in describing a certain thing. It is the same with Sumtu poetry, which describes Palestine's longing for Gaza. This study aims to determine the form of the intrinsic and extrinsic elements in Mahmud Darwish's Sumtu Min Ajli Ghazah based on Goldman's perspective. This research is a descriptive qualitative study with a genetic structuralism approach. In collecting the data, the researcher applied reading and note-taking techniques. Then, they were analyzed based on the Miles and Huberman model. The results showed that the concept of human facts were the problems of misery, oppression, and human violence in Palestine. The concept of a collective subject was a representation of two large conflicting groups consisting of the Israeli Society as superior and the Gazan people as inferior. This poem's world view is to reveal the author's partiality to the Palestinian people to face Israeli oppression. Besides, the concept of understanding - explanation describes societal factors and individual factors. The social factor was also the author's concern for the social situation around him caused by humanitarian problems that never end. Meanwhile, the individual factor that appeared in the poetry reflects the author's thoughts and feelings towards humanitarian problems that never stop in his country.
Correlation of Skin Pigmentation Changes as a Side Effect of Clofazimine Treatment with Anxiety Level in MDR-TB Patients at Dr. Soebandi Hospital Sudjarwo, Raisa; Firdaus, Jauhar; Raharjo, Angga
International Journal of Health and Information System Vol. 3 No. 2 (2025): September
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/ijhis.v3i2.57

Abstract

Clofazimine, used to treat Multidrug-resistant tuberculosis (MDR-TB), often causes skin pigmentation changes, potentially impacting patients' self-esteem and anxiety. Anxiety represents a common but often underrecognized comorbidity in MDR-TB patients, who are challenged by lengthy treatment regimens, social stigma, and distressing adverse effects. This study aimed to examine this correlation at Dr. Soebandi Hospital. The study utilized an observational analytic method with a cross-sectional design. The population was all MDR-TB patients in Dr. Soebandi hospital, presented from April to May 2024. We recruited 67 patients using a total sampling technique. We analyzed the primary data from the respondents: 1) Respondents' self-rating of skin pigmentation change; 2) Hamilton Anxiety Rating Scale (HARS) score. We also checked the medical records to analyze the respondents' treatment history. The data were analyzed using the chi-square test. Most respondents were male and in a productive age. The chi-square test results show a p-value of 0.822, indicating no significant correlation between skin pigmentation changes and anxiety levels in MDR-TB patients. Clofazimine-induced skin pigmentation changes had no significant correlation with the anxiety levels among MDR-TB Patients at Dr. Soebandi Hospital. Further studies should consider methodological improvements, including prospective design, larger sample size, mixed method, and involvement of dermatology experts in assessing the skin changes induced by clofazimine. Recognizing individual differences in psychological response highlights the need to offer reassurance, counseling, and psychosocial support for MDR-TB patients.
Tobacco Dust Exposure Among Tobacco Workers in Jember Reduces Lung Function Capacity Nofica, Cheila; Firdaus, Jauhar; Rachmania, Sheilla; Caesarina, Ancah
International Journal of Health and Information System Vol. 3 No. 2 (2025): September
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/ijhis.v3i2.60

Abstract

This study investigated the association between urinary cotinine levels and lung function among tobacco workers in Jember Regency, a major tobacco-producing region in Indonesia. A total of 48 respondents were included based on specific inclusion and exclusion criteria. Urinary cotinine levels were measured using enzyme-linked immunosorbent assay (ELISA), and lung function was assessed via spirometry. Based on FEV1/FVC ratios, 58% of participants exhibited restrictive lung patterns, 29% showed obstructive patterns, and 13% had normal pulmonary function. Statistical analysis conducted using SPSS, with a significance level set at p < 0.05, indicated no statistically significant correlation between urinary cotinine levels and lung function.
Co-Authors Abu Khoiri Achmad Subagio Adelia Handoko Aisya, Meutia Citra Al Munawir Alif Kufari Alyssandra Afqorina Agung Amini, Stefia A. Andi Muhammad, Andi Angela, Patricia Angga Mardro Raharjo Aris Prasetyo Aris Prasetyo Azham Purwandhono Bagus Hermansyah Bagus Satrio Pambudi Bagus Satrio Pambudi, Bagus Satrio Baidowi, Ivan Iqbal Caesarina, Ancah Cahyana, Nugraha Wahyu Cicih Komariah Dini Agustina Dita Diana Parti El Milla, Kardiana Izza Elly Nurus Sakinah, Elly Nurus ENNY SUSWATI Erma Sulistyaningsih Fambudi, Stela S. Habibbur Rochman Salim Hairrudin Hairrudin Handoko, Adelia Haniefah, Yumna Rifda Heni Fatmawati Ida Srisurani Wiji Astuti Inke Kusumastuti Inreswari, Laksmi Irawan Fajar Kusuma Karim, Muhdie Karisma Adya Pertiwi Komang Dewi Fridayanti Kristianingrum Dian Sofiana Kristianingrum Dian Sofiana Kristianningrum Dian Sofiana Labibah, Zhafirah Rana Laksmi Indreswari Lubis, Arinie Awindya Marchianti, Ancah CN. Maria Ulfa Moh. Nur Indra Caesar Muhammad Fakhri Ali Muhammad Rijal Fahrudin Hidayat Nabiel, Rifaldy Ngurah Agung Reza Satria Nugraha Putra Nofica, Cheila Nurud Diniyah Pattipeilohy, Florence Pattipeilohy, Florence Marianty Pipiet Wulandari Pralampita, Pulong Wijang Prasetyo, Aris Putri, Dhiani E. Raharjo, Angga Rumastika, Nindya Shinta Sakinah, Elly N. septa surya wahyudi, septa surya Setia, Bagus Sheilla Rachmania, Sheilla Sofiana, Kristianingrum Dian Sudarmanto, Yohanes Sudjarwo, Raisa sulihah, nurfaizah titisari Supangat Supangat Supangat Supangat Suryono Suryono T Ariani Widiastini Tartila, Jasmine Tristianti, Farmitalia Nisa Winanda, Leony Agnes Savira Wulan, Herlina Nur Yonas Hadisubroto Yudha Nurdian Yuli Hermansyah Zahrah Febianti