Garuda - Garba Rujukan Digital

p-Index From 2021 - 2026

1.881

P-Index

This Author published in this journals

All Journal CHEMICA Jurnal Teknik Kimia ALCHEMY Jurnal Penelitian Kimia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi Indonesia Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal AFAMEDIS Jurnal Bakti Untuk Negeri Jurnal Komunitas Farmasi Nasional Borneo Journal of Pharmacy Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Journal of Pharmascience

Siska Musiam

Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Author-ID : 3017078

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Energy Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

Published : 28 Documents Claim Missing Document

Claim Missing Document

Articles

1 2 3

UJI BIOLARVASIDA EKSTRAK METANOL DAUN JERUK NIPIS (Citrus aurantifolia) TERHADAP LARVA NYAMUK Aedes aegypti L Siska Musiam; Maya Armianti; Aditya Maulana Perdana Putra
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 3 No 1 (2018): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Nyamuk Aedes aegypti L. adalah vektor penularan penyakit Demam Berdarah Dengue (DBD). Pengendalian vektor nyamuk Aedes aegypti L. dengan menggunakan larvasida dilakukan sebagai upaya penanggulangan penyakit DBD. Pada penelitian ini dilakukan pengujian aktivitas dari ekstrak metanol daun jeruk nipis (Citrus aurantifolia) sebagai biolavasida nyamuk Aedes aegypti L. Konsentrasi ekstrak metanol daun jeruk nipis (Citrus aurantifolia) yang digunakan dalam penelitian ini adalah 0,1%; 0,2%; 0,3%; dan 0,4%. Temephos 1% digunakan sebagai kontrol positif dan air keran sebagai kontrol negatif. Setiap perlakuan menggunakan 20 larva Aedes aegypti L. Instar III dan direplikasi sebanyak empat kali. Hasil analisis SPSS menyatakan bahwa ada pengaruh konsentrasi terhadap jumlah kematian larva uji, dimana pada konsentrasi 0,3%, 0,4% dan kontrol positif Temephos 1% tidak menunjukkan perbedaan jumlah kematian larva uji yang bermakna. Nilai LC50 yang didapatkan berada pada interval 0,089% sampai 0,123% dengan estimasi konsentrasi 0,108%.

UJI AKTIVITAS EKSTRAK ETANOL KULIT ARI BUAH JENGKOL (Pithcelobium jiringa) SEBAGAI BIOLARVASIDA NYAMUK (Aedes aegypti L.) Noverda Ayuchecaria; Nida Munirah; Amaliyah Wahyuni; Eka Kumalasari; Ratih Pratiwi Sari; Siska Musiam
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Larvasida is still the first line in the prevention of Dengue Hemorrhagic Fever (DHF) disease caused by Aedes aegypti L. mosquitoes. Indonesia itself as a tropical country has many beneficial plants, one of which is Pithcelobium jiringa pericarp. Until now, the use of pericarp is still lacking even though jengkol fruit peels contain secondary metabolites such as flavonoids, saponins, tannins and triterpenoids, which have larvacidal effects. The purpose of this study was to determine the activity of ethanol extract of Pithcelobium jiringa pericarp as biolarvasida of Aedes aegypti L. mosquitoes from LC50 values. The treatment concentration used in this study was concentrations of 10%, 30%, and 50%. Temephos 1% is used as a positive control. The concentration was then tested on 20 Aedes aegypti L. larvae. The results showed that there was a treatment effect (sig <0.05) on the number of larval deaths, which from the results of Tuckey's analysis showed that 30% and 50% concentrations and 1% Temephos showed significant differences in the number of test larvae deaths. The results showed that the extract was effective as biolarvasida of Aedes aegypti L. mosquitoes. The results of probit analysis showed LC50 extract to Aedes aegypti L. larvae was 20.4716% which is a low toxin group in aquatic environments.

POTENSI KOMBINASI KAPUR SIRIH DAN DAUN KUMPAI MAHUNG (Eupatorium inulifolium H.B&K.) SEBAGAI ALTERNATIF SALEP ANTI INFLAMASI ALAMI Dwi Rizki Febrianti; Siska Musiam
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Kumpai Mahung (Eupathorium inulifolium H.B & K) is one of an endemic plant in South Kalimantan. Hereditary used as traditional medicine. kapur sirih (calcium carbonate) is also used by the community as a food additive (BTP), especially in the manufacture of chips and fruit ice. Traditionally these two ingredients are combined to treat swollen (oedema) mastitis in nursing mothers. This research method using raw test pad oedema in legs male rats. simple ointment dosage form, induction carrageenan 3% and hydrocortisone as a positive control anti-inflammatory calculated the value and the value AUC (area under the curve). the results expressed Ointment combination Kumpai Mahung leaf extract and calcium carbonate have anti-inflammatory power of 14.91% greater than the positive control 9.95%.

SINTESIS NANOKITOSAN DARI LIMBAH CANGKANG HALILING (Filopaludina javanica) KALIMANTAN SELATAN Siska Musiam; Noor Aisyah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 2 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Haliling (Filopaludina javanica) is usually consumed as a side dish by the people of South Kalimantan by taking part of the meat, then the shell is disposed as untapped waste. This research utilizes the waste from the haliling shell as raw material for chitosan synthesis. Chitosan is a multipurpose natural polymer used in the biomedical field as a protective active drug. Haliling shell powder deproteinated with a solution NaOH 4%(w/v) of 10:1 ratio by refluxing for 2 hours at 100Ãƒâ€šÃ‚Â°C. The results of the deproteination reaction were demineralized with a solution of HCl 1 N of 15:1 ratio which was stirred for 2 hours at room temperature. Furthermore, the demineralization reaction results are depigmented with a solution of NaOCl 0.315%(w/v) of 10:1 ratio which was stirred for 2 hours at 40Ãƒâ€šÃ‚Â°C to obtain chitin. Deacetylation reaction was carried out on chitin using a solution of NaOH 60%(w/v) of 20:1 ratio by refluxing it for 2 hours at 80Ãƒâ€šÃ‚Â°C so that chitosan was obtained. Chitosan nanoparticles were synthesized using the ionic gelation method with sodium tripolyphosphate crosslinker. The product obtained is known as chitosan based on the results of FTIR analysis which shows the emergence of the -NH2 amine group at wave number 3300-3500 cm-1 with an average size of chitosan nanoparticles of 500 nm.

AKTIVITAS ANTIFUNGI FLAVONOID DARI EKSTRAK DAUN Citrus aurantifolia KALIMANTAN SELATAN TERHADAP PERTUMBUHAN Candida albicans Siska Musiam; Fitria Ulfah; Imam Agus Faisal; Eka Kumalasari; Riza Alfian
AFAMEDIS Vol. 1 No. 1 (2020): Jurnal Farmasi Indonesia AFAMEDIS
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (128.656 KB)

Candida albicans adalah jamur paling mudah menginfeksi yang menyebabkan banyak penyakit seperti infeksi mulut, infeksi saluran kemih, dan infeksi saluran pencernaan. Salah satu alternatif untuk menyembuhkan penyakit jamur adalah menggunakan ramuan herbal yang mengandung senyawa flavonoid yang dapat menghambat pertumbuhan strain Candida albicans. Citrus aurantifolia adalah salah satu tanaman obat yang digunakan sebagai penambah nafsu makan, antipiretik, diare, menurunkan berat badan, antiinflamasi, dan antibakteri. Tujuan dari penelitian ini adalah untuk mengetahui kandungan senyawa flavonoid yang ada pada daun Citrus aurantifolia dan kemampuannya untuk menghambat pertumbuhan strain Candida albicans menggunakan metode in-vitro. Pada penelitian ini, senyawa flavonoid dalam daun Citrus aurantifolia diekstraksi dengan metode maserasi menggunakan pelarut etanol. Penentuan kadar flavonoid dilakukan menggunakan spektrofotometri UV-Visible dengan panjang gelombang 417 nm dan diperoleh kadar 34,42% (b/v). Kelompok perlakuan aktivitas antifungi menggunakan ekstrak etanol daun Citrus aurantifolia dengan konsentrasi 50%; 60%; 70%; 80%; 90%; dan 100%. Uji daya hambat Candida albicans dilakukan dengan menggunakan metode difusicakram . Hasil penelitian menunjukkan konsentrasi 80%, 90% dan 100% memiliki aktivitas antifungi dengan rata-rata zona hambat masing-masing 3,36 mm; 4,08 mm; dan 8,30 mm.

PEMANFAATAN LIMBAH SAYUR SEBAGAI BAHAN BAKU PUPUK CAIR OLEH ANAK USIA SEKOLAH DASAR DI DESA TATAH LAYAP Siska Musiam; Eka Kumalasari
Jurnal Bakti untuk Negeri Vol 1 No 1 (2021)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.007 KB)

Limbah dari sayuran merupakan salah satu limbah rumah tangga yang berkontribusi dalam pencemaran lingkungan. Limbah sayuran mengandung unsur makro yang masih dapat dimanfaatkan menjadi sesuatu yang berguna. Salah satu solusi pemanfaatan limbah sayuran ini adalah dengan membuatnya menjadi pupuk cair organik yang kemudian dapat dimanfaatkan untuk meningkatkan pertumbuhan tanaman rumahan. Telah dilakukan kegiatan pengabdian kepada masyarakat dalam pelatihan pembuatan pupuk cair dari limbah sayuran kepada anak usia sekolah dasar di Desa Tatah Layap. Hasil dari kegiatan ini berupa diperolehnya pemahaman oleh anak-anak usia sekolah dasar tentang cara pemanfaatan dan pengolahan limbah sayuran menjadi pupuk cair.

Penetapan Kadar Flavonoid Ekstrak dan Fraksi Kulit Buah Citrus reticulata Siska Musiam; Erna Prihandiwati; Eka Kumalasari; Aisyah Aisyah
Jurnal Farmasi Indonesia Vol 19 No 2 (2022): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v19i2.1343

Citrus reticulata is one of the varieties of citrus endemic to South Kalimantan. So far, the people of South Kalimantan have only used the pulp of the citrus fruit, while the skin is disposed of as waste. Therefore, this study was conducted to see the value of the benefits of the Citrus reticulata rind waste by testing the levels of flavonoids from the extract and its fractions. The rind extraction of Citrus reticulata was carried out by maceration method using methanol as a solvent. The extract obtained was then fractionated using the liquid-liquid method using n-hexane, chloroform, ethyl acetate, and water as solvents. The extract and each fraction were determined for the level of flavonoids using a UV-Visible spectrophotometer at a wavelength of 413 nm and a series of standard concentrations of quercetin 35; 50; 65; 80; and 95 ppm. The results showed that the levels of flavonoids from the highest to the lowest were in the water fraction, methanol extract, n-hexane fraction, ethyl acetate fraction, and chloroform fraction with the respective values of 53.635 ± 0.00697; 30.083 ± 0.00386; 15,524 ± 0.00423; 9.787 ± 0.00198%(w/w).

POTENSI KOMPOSIT OKSIDA LOGAM-KITOSAN SEBAGAI AGEN ANTIDIARE Siska Musiam; Eka Kumalasari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 2 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i2.1535

Diarrhea is a defecation disorder characterized by defecating more than three times a day with a liquid stool consistencBABy, which may be accompanied by blood and/or mucus. Infection is still the main cause of diarrhea. The large number of cases of diarrhea due to infection means that antibiotics are still widely used in treating diarrhea. Irrational use of antibiotics can result in the emergence of side effects and resistance. To prevent this, diarrhea treatment can use materials that are able to absorb toxins and bacteria in the digestive tract, and are safe for the human body. Chitosan is an environmentally friendly material that has a large network of pores. Some metal oxides have been found to have good chemical affinity. The metal oxide-chitosan composite in nano size is predicted to allow the absorption of toxins and bacteria, but is easily released again by the body. In this research, metal oxide (Fe)-chitosan composite material was synthesized using 2 methods designed to have an antidiarrheal effect. The antidiarrheal effect is observed by its ability to absorb liquids containing natural ingredients. The results of this research showed that the composite material synthesized using a liquid reaction (13,861 ppm to 11,082 ppm) produced a stronger adsorption capacity compared to the composite material synthesized using a solid reaction (13,861 ppm to 11,265 ppm).

AKTIVITAS MINYAK ATSIRI BUNGA LILY (Lilium auratum) TERHADAP BAKTERI Salmonella typhi Dwi Rizki Febrianti; Siska Musiam; Dani Kurniawan
Jurnal Komunitas Farmasi Nasional Vol. 1 No. 2 (2021): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar

Salmonella typhi infection caused by Salmonella typhi attacks the intestinal tract and breeds there. Types of raw food and seafood can be contaminated by this bacteria. The risk of infection is high in patients with congenital inflammatory bowel disease and immune problems. The potential of natural materials such as lilies has not been explored much. The components of lily essential oil compounds contain benzaldehyde, linalool, cement, borneol and osimen which can react with bacterial cell wall components causing damage to bacterial cell walls. The purpose of this study was to determine the potential of lily flower essential oil (Lilium auratum) in inhibiting the growth of salmonella typhi bacteria. Using with a concentration of 10%, 30%, 50% and 70%. The results of the test using the disc method showed that lily essential oil was able to inhibit bacteria with inhibition zones of 10% (13.83 mm), 30% (13.25 mm), 50% (15.05 mm) and 70% (15.26 mm) with a strong category.

Combination of Bawang Dayak Extract and Acarbose against Male White Rat Glucose Levels Aditya Maulana Perdana Putra; Ratih Pratiwi Sari; Siska Musiam
Borneo Journal of Pharmacy Vol. 4 No. 2 (2021): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v4i2.1703

Diabetes is a chronic metabolic disease with signs of increased blood glucose levels. Type 2 diabetes is common diabetes in adults. Bawang dayak is one of the plants believed to have the efficacy of curing various types of diseases. The purpose of this study was to find out the comparison of hypoglycemic effects between combinations of bawang dayak extract and acarbose with single acarbose. This study was an experimental study using 32 white mice divided into two groups. Group one was given a combination of bawang dayak at a dose of 100 mg/kg BW and acarbose at a dose of 40 mg/100 g BW, while group two was given acarbose at a dose of 40 mg/100 g BW. Treatment is administered after the test animal is induced with dexamethasone at a 1 mg/kg BW dose dissolved in NaCl 0.9% subcutaneously for 12 days. Measurement of glucose levels was carried out using a glucometer. Data retrieval was carried out every three days for 15 days after previously fulfilled for +10 hours. Blood glucose level data were analyzed with the General Linear Model test. The combination of bawang dayak-acarbose onion extract had a greater decrease in blood glucose levels than single acarbose. Average reduction in blood glucose levels for D+3; D+6; D+9; D+12; and D+15 was 187.31; 168.56; 140.81; 119.81; and 102.56 mg/dl, respectively. The General Linear Model test results showed a p <0.05 value that significantly impacted blood glucose levels between groups.

Co-Authors Agus Ariyanto Aisyah Aisyah Aisyah, Noor Amanah, Ike Nur Anna Khumaira Sari Ariani, Novia Ariani, Novia Ayu Lestari, Desy Ayuchecaria, Noverda Dani Kurniawan Darmiani, Siti Eka Kumalasari Eka Kumalasari Eka Kumalasari Eka Kumalasari Erna Prihandiwati Febrianti, Dwi Rizki Fitria Ulfah Hamidah, Marina Imam Agus Faisal Indah Fitri Ramadhani Maida Safutri Marina Hamidah Maya Armianti Muhammad Ma'ruf Muhammad Ma'ruf Nazulla Mudjib Nararia Nida Munirah Novia Ariani Prasdianto Prasdianto Prihandiwati, Erna Puteri Amalia, Senya Putra, Aditya Maulana Perdana Putri, Megawati Ayu Rakhmadhan Niah Ratu Mouly Noor Renny Renny Riza Alfian Rizki Febrianti, Dwi Saftia Aryzki Safutri, Maida Saputra, Marhan Ebit Sari, Ratih Pratiwi shafran ilahi, fitrah Siti Darmiani Susanto, Yugo Verry Andre Fabiani Wahyuni, Amaliyah

Title

Found 28 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 28 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 28 Documents
Search