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ELECTROCARDIOGRAM OF PIGS (Sus scrofa) ANESTHETIZED WITH A COMBINATION OF KETAMINE-MEDETOMIDINE AND KETAMINE-ACEPROMAZINE Jessica Anggun Safitri; Gunanti Gunanti; Deni Noviana; Sus Derthi Widhyari
Jurnal Kedokteran Hewan Vol 14, No 4 (2020): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (331.403 KB) | DOI: 10.21157/j.ked.hewan.v14i4.16984

Abstract

This study aims to evaluate and compare the effects of the combination of ketamine-medetomidine and ketamine-acepromazine anesthesia on pig electrocardiogram (ECG) images. The study was conducted to see the ECG Leads II in six pigs which were divided into two groups. Group I (K1) was given a combination of ketamine (10 mg/kg BW) and medetomidine (0.08 mg/kg BW), while Group II (K2) was given a combination of ketamine (22 mg/kg BW) and acepromazine (1.1 mg/kg BW) intramuscularly. ECG recording was performed after the pigs were anesthetized at the surgical stage by attaching the recording electrodes to the front wall of the chest, front left and right ankles, and back right and left back ankles. The ECG recording used 1 voltage (1 cm = 1mV) with a speed of 25 mm/sec. The parameters observed were heart rate frequency, heart rhythm, P duration, P amplitude, PR interval, R amplitude, QRS interval, QT interval, ST segment, T wave, and Mean Electrical Axis (MEA). Data obtained from this study were analyzed by T-test. The results showed that K1 had an average heart rate of 100 x/minute, regular heart rhythm, P duration of 0.07 sec, P amplitude of 0.27 mV, PR interval of 0.17 sec, R amplitude of 0.75 mV, QRS interval of 0.05 sec, QT interval of 0.20 sec, ST segment of 0.17sec, T wave of 0.17 mV, and MEA of 83.60°; meanwhile, K2 had an average heart rate of 122 x/minute, regular heart rhythm, P duration of 0.06 mm/sec, P amplitude of 0.23 mV, PR interval of 0.14 sec, R amplitude of 0.80 mV, QRS interval of 0.04 sec, QT interval of 0.16 sec, ST segment of 0.14 sec, T wave of 0.12 mV, and MEA of 68.60. The ketamine-medetomidine combination produced good quality of anesthetics for the cardiovascular system.
ELECTROCARDIOGRAM OF PIGS (Sus scrofa) ANESTHETIZED WITH A COMBINATION OF KETAMINE-MEDETOMIDINE AND KETAMINE-ACEPROMAZINE Jessica Anggun Safitri; Gunanti Gunanti; Deni Noviana; Sus Derthi Widhyari
Jurnal Kedokteran Hewan Vol 14, No 4 (2020): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v14i4.16984

Abstract

This study aims to evaluate and compare the effects of the combination of ketamine-medetomidine and ketamine-acepromazine anesthesia on pig electrocardiogram (ECG) images. The study was conducted to see the ECG Leads II in six pigs which were divided into two groups. Group I (K1) was given a combination of ketamine (10 mg/kg BW) and medetomidine (0.08 mg/kg BW), while Group II (K2) was given a combination of ketamine (22 mg/kg BW) and acepromazine (1.1 mg/kg BW) intramuscularly. ECG recording was performed after the pigs were anesthetized at the surgical stage by attaching the recording electrodes to the front wall of the chest, front left and right ankles, and back right and left back ankles. The ECG recording used 1 voltage (1 cm = 1mV) with a speed of 25 mm/sec. The parameters observed were heart rate frequency, heart rhythm, P duration, P amplitude, PR interval, R amplitude, QRS interval, QT interval, ST segment, T wave, and Mean Electrical Axis (MEA). Data obtained from this study were analyzed by T-test. The results showed that K1 had an average heart rate of 100 x/minute, regular heart rhythm, P duration of 0.07 sec, P amplitude of 0.27 mV, PR interval of 0.17 sec, R amplitude of 0.75 mV, QRS interval of 0.05 sec, QT interval of 0.20 sec, ST segment of 0.17sec, T wave of 0.17 mV, and MEA of 83.60°; meanwhile, K2 had an average heart rate of 122 x/minute, regular heart rhythm, P duration of 0.06 mm/sec, P amplitude of 0.23 mV, PR interval of 0.14 sec, R amplitude of 0.80 mV, QRS interval of 0.04 sec, QT interval of 0.16 sec, ST segment of 0.14 sec, T wave of 0.12 mV, and MEA of 68.60. The ketamine-medetomidine combination produced good quality of anesthetics for the cardiovascular system.
MANAGEMENT OF ENUCLEATION SURGERY IN MAINE COON CAT Syarifuddin, Ahmad; Damhuri, Dedi; Safitri, Jessica Anggun; Wibowo, Sarwo Edy
VITEK : Bidang Kedokteran Hewan Vol 14 No 2 (2024): VITEK-Bidang Kedokteran Hewan
Publisher : Fakultas Kedokteran Hewan Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jv.v14i2.309

Abstract

Enucleation is a procedure for removing the eye in cats due to pathological conditions that cannot be treated with medical therapy, such as uncontrolled glaucoma or intraocular tumors. Prolapse of the bulbus oculi in cats is generally caused by glaucoma (increased intraocular pressure), bacterial or viral infections, trauma from being hit by a vehicle, scratches or fights with other animals, and eye tumors. The subject of this case was a male cat named Chiko, approximately 1 year old, weighing 2.5 kg, who was brought to the She Wee Veterinary Clinic in Palembang with the complaint of a protruding eye. Based on the anamnesis, physical examination, and clinical symptoms, Chiko was diagnosed with bulbus oculi prolapse and underwent medical treatment in the form of an enucleation surgery. The treatment administered included antibiotics, vitamins, analgesics, and ointments. The use of an Elizabethan collar was also recommended to prevent the wound from being scratched. Recovery showed good wound healing within approximately 7 days without serious complications. It was concluded that the enucleation procedure performed on Chiko, using the transpalpebral technique, had a fausta prognosis. Keywords: Prolapse, Bulbus Oculi, Enucleation, Eye and Cat.
Management of Digit Papillomas in Golden Retriever Dogs Jessica Anggun Safitri; Sarwo Edy Wibowo; Ahmad Syarifuddin; Dedi Damhuri; Puti Puspa Seruni; Asri Rizky
Journal of Applied Veterinary Science And Technology Vol. 6 No. 1 (2025): April 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/javest.V6.I1.2025.76-80

Abstract

Background: Papillomas are benign tumors that affect the skin or soft tissue beneath the skin. These papillomas can be accompanied by various abnormalities such as pustules, itching, hematomas, cysts, blisters, abscesses, lick granulomas, and skintags. While papillomas may resolve on their own, some cases require intensive treatment and management. Purpose: To provide veterinarians with insights into diagnosing and managing papilloma cases. Case: A 10-year-old male Golden Retriever presented with an open wound on the left front paw nail. The wound originated from a broken nail, which led to a non-healing wound over a period of 2 months. Clinical examination revealed a mass-like lesion that had ruptured. Palpation of the left front paw nail area indicated an irregular, lobular growth resembling grapes or cauliflower. Case Management:  Routine hematology revealed that the dog had microcytic hypochromic anemia, while blood chemistry indicated mildly reduced kidney function. Cytology confirmed that the wound was a papilloma. Treatment involved digit amputation to completely remove the tumor mass, along with wound care that included the application of ointments, antibiotics, analgesics, hematopoietic agents, anti-bleeding medication, and anti-cancer drugs. Supportive treatment included multivitamins, nerve supplements, immune supplements, and skin and coat supplements (Coatex). By the fifth postoperative day, the wound had dried, and the edges were healing well. Conclusion: Papillomas are benign and not harmful, but it is recommended to completely remove the tumor mass to prevent secondary infections.
The Treatment of A Case of Feline Panleukopenia Virus in a Mixed Persian Cat Ahmad Syarifuddin; Jessica Anggun Safitri; Sarwo Edy Wibowo; Dedi Damhuri; Amelia Triningsih Triningsih
Journal of Applied Veterinary Science And Technology Vol. 6 No. 1 (2025): April 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/javest.V6.I1.2025.81-84

Abstract

Background: Feline panleukopenia virus (FPV) is a highly contagious and frequently fatal disease, particularly affecting unvaccinated juvenile cats. Clinical manifestations typically include leukopenia, diarrhea, dehydration, vomiting, and depression. The disease exhibits high morbidity and mortality rates, especially in young animals without prior immunization. Purpose:  This report aims to provide clinical insight into the diagnosis and symptomatic management of FPV in domestic cats. Case: An 8-month-old unvaccinated female cat weighing 2.3 kg was presented with signs consistent with panleukopenia. The patient had not received deworming treatment and lived in a semi-outdoor environment with three other cats. Physical examination focused on the oral cavity, nasal passages, eyes, ears, and abdomen. Hematological findings supported suspicion of viral infection. The history revealed that the patient’s littermates had died after exhibiting similar symptoms. Case Management:  Therapy focused on symptomatic treatment, including the administration of broad-spectrum antibiotics (ceftriaxone) to prevent secondary bacterial infections and reduce the risk of septicemia. Gastric protection was provided using ranitidine to inhibit gastric acid secretion and prevent complications such as ulcers and esophageal erosion. Supportive management also included fluid therapy and antidiarrheal care tailored to the patient's clinical status. Conclusion: Prompt diagnosis and appropriate symptomatic management significantly influence the outcome of FPV cases. Preventive strategies, including vaccination and routine deworming, remain essential in reducing the incidence and severity of infection. This case highlights the importance of early intervention and individualized treatment in improving recovery and survival rates in cats affected by panleukopenia.
Gambaran Darah dan Status Kesehatan pada Kambing Peranakan Etawa (PE) yang Mengalami Abortus: Laporan Kasus Wibowo, Sarwo Edy; Harahap, Ratna Sholatia; Nugraheni, Yudhi Ratna; Awaludin, Aan; Rahayu, Pudji; Rosadi, Bayu; Yatno, Yatno; Syarifuddin, Ahmad; Damhuri, Dedi; Safitri, Jessica Anggun
Jurnal Ilmiah Ilmu-Ilmu Peternakan Vol 28 No 1 (2025): Mei 2025
Publisher : Fakultas Peternakan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jiiip.v28i1.36323

Abstract

Latar Belakang: Abortus merupakan masalah reproduksi yang dipengaruhi oleh status kesehatan ternak yang menyebabkan kerugian pada ternak seperti kambing. Tujuan: Penelitian ini dilakukan untuk mengetahui gambaran darah dan status kesehatan pada kambing yang mengalami abortus di Fapet Farm Fakultas Peternakan Universitas Jambi. Metode: Metode yang digunakan dalam penelitian ini diawali dengan pencatatan identitas ternak, anamnesa, dan pemeriksaan fisik pada kambing PE yang menunjukkan gejala klinis sakit. Sampel darah dan feses kemudian diambil dari lima ekor kambing yang mengalami abortus untuk dilakukan pemeriksaan telur cacing, parasit darah, dan serologi terhadap Brucella sp yang diduga sebagai penyebab terjadinya abortus. Hasil: Hasil analisis pemeriksaan darah dan kesehatan yang dilakukan ditemukan bahwa adanya infeksi parasit pada pada lima kambing yang mengalami abortus. Empat kambing yang terinfeksi parasit Anaplasma sp., yaitu kambing 2, kambing 3, kambing 4, dan kambing 5. Dua kambing positif terinfeksi parasit gastrointestinal, yaitu ditemukan telur cacing Paramphistomum sp. dan Haemonchus sp., pada kambing 1, sedangkan kambing 2 ditemukan telur cacing Paramphistomum sp. dan Moniezia sp. Hasil pemeriksaan hematologi terdapat peningkatan leukosit pada kambing nomor 5 dan penurunan nilai hematokrit pada kelima kambing dan MCHC pada kambing nomor 3 dan 4. Kesimpulan: Kondisi abortus yang dialami kambing PE di Fapet Farm Fakultas Peternakan Universitas Jambi terjadi karena adanya infeksi parasit, peningkatan leukosit, dan penurunan nilai hematokrit yang ditemukan pada sampel darah dan feses yang diuji.
Serum IL-6 AS A marker of immuno-inflammatory response to Zn-Mg alloy implants in porcine (Sus scrofa) Hafizsha, Nabila Latifa; Safitri, Jessica Anggun; Ulfa, Rasyida; Khalid, Idham; Agung, Nabilah Putroe; Makmur, Ali; Fitriana, Rizky
The International Journal of Tropical Veterinary and Biomedical Research Vol 10, No 1 (2025): Vol 10 (1) May 2025
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/ijtvbr.v10i1.45637

Abstract

Background and Aim: The present study aimed to evaluate the immune-inflammatory response induced by ZnMg(3x) and ZnMg(4x) alloy implants in the porcine urinary bladder by measuring serum interleukin-6 (IL-6) levels.Materials and Methods: Nine porcines, aged 2-3 months old with 25-30 kg body weight, were divided into three groups: ZnMg(3x), ZnMg(4x), and control, while the observation time was performed on days 0, 14, and 28. Implantation was performed on the urinary bladder using cystotomy techniques. Measurement of IL-6 levels is done using enzyme-linked immunosorbent assay (ELISA). Data were analyzed statistically using analysis of variance (ANOVA).Results : The results showed that at day 0 for the ZnMg(3x) and ZnMg(4x) implants were 0.53 0.92 pg/mL and 0.10 0.17 pg/mL, respectively. On day 14, IL-6 levels in both implants decreased, although not significantly. On day 28, a slight increase was observed in ZnMg(3x) compared to ZnMg(4x), but this was also not significant (P0.05).Conclusion: Based on the results, Zn-Mg materials are suitable to be used as urinary stent base materials.
Clinical Outcomes of Autologous Serum Eye Drops in Treating Corneal Ulceration in a Domestic Cat: A Case Base Study Eka Putri, Rahmi; Hilmi, Mulkiah; Rahmi, Ulfa; Zamzami, Rumi Sahara; Etriwati, Etriwati; Erwin, Erwin; Sugito, Sugito; Syah, Nada Yulian; Ferdian, Riyan; Sari, Wahyu Eka; Safitri, Jessica Anggun
Jurnal Medika Veterinaria Vol 19, No 2 (2025): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v19i2.46171

Abstract

Corneal ulceration is a frequent ophthalmic disorder in domestic cats that can cause ocular discomfort, visual impairment, and serious complications if left untreated. Conventional medical management often provides limited support for epithelial regeneration, leading to the need for alternative therapeutic options. This case study reports the clinical outcome of using autologous serum eye drops (ASEDs) in the treatment of corneal ulceration in a domestic cat. A cat presented with severe epiphora, conjunctival hyperemia, and a centrally located corneal ulcer confirmed by fluorescein staining. Autologous serum was prepared by weekly collection of 6 mL of blood from the dorsalis antebrachii vein, followed by centrifugation and aliquoting into sterile eye drop bottles stored at 4 C. The serum was applied topically twice daily, accompanied by supportive therapy consisting of vitamin A supplementation, multivitamin injections, and an Elizabethan collar to prevent self-trauma. Clinical scoring (03) was used to monitor epiphora, conjunctival hyperemia, and corneal opacity over the treatment period. Marked improvement was observed within 14 days: epiphora and conjunctival hyperemia resolved completely, while corneal opacity improved from moderate to mild, with fluorescein staining becoming negative, indicating complete epithelial closure. No adverse effects were recorded during therapy. This case highlights the potential of autologous serum eye drops as a safe and effective adjunct treatment for feline corneal ulceration, warranting further investigation in larger cohorts to establish standardized protocols for veterinary ophthalmology