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PEMBUATAN RADIOFARMAKA PET 18F_FDG MENGGUNAKAN MODUL SINTESA OTOMATIK Purwoko, Purwoko; Chairuman, Chairuman; Gunawan, Adang Hardi; Tahyan, Yayan; Lestari, Eny; Lestiyowati, Sri Aguswarini; Karyadi, Karyadi; Bagiawati, Sri
Jurnal Radioisotop dan Radiofarmaka Vol 13, No 2 (2010): Jurnal PRR 2010
Publisher : Jurnal Radioisotop dan Radiofarmaka

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Abstract

ABSTRAKPEMBUATAN RADIOFARMAKA PET 18F_FDG MENGGUNAKAN MODUL SINTESAOTOMATIK.Radiofarmaka 2-(18F)Fluoro-2-deoksi-O-glukosa at au ISF(FOG) adalah radiofarmaka PET(Positron Emission Tomography) yang sangat penting untuk pencitraan lesi tumor. Oengan teknik PETmetabolisme glukosa dalam jaringan tumor di dalam tubuh dapat dibedakan dan diukur secara kuantitatifsehingga digunakan untuk diagnosa tingkat keganasan serta pemantauan pengobatan penyakit tumor ataukanker dalam bidang onkologi kedokteran. Telah dilakukan uji coba produksi 2-(lSF)Floro-2-deoksi-OglukosaISF_ FOG menggunakan perangkat modul sintesa otomatik TRACERlab MX. Perangkat modul inimemberikan kemudahan dalam sintesa rutin radiofarmaka lsF_FOG yang didasarkan pad a reaksi tlorinasinukleofilik terhadap prekursor manosa tritlat dengan katalisator kriptofik. Perolehan yield radiokimia lSF(FOG) mencapai 53,895% (tanpa koreksi waktu peluruhan) dalam waktu 40 men it, produk berupa larutanjernih tak berwarna pH : 6, steril dan bebas pirogen, kadar pengotor kriptofix sangat rendah dan kemurnianradiokimia 99,595 %.Kata kunci: PET, radiofarmaka,PRODUCTION OF PET RADIOPHARMACEUTICAL 18F_FDG USING SYNTHESIZERAUTOMATIC MODUL.Radiopharmaceutical 2-esF)Fluoro-2-0eoxy-O-Glukose or IsF(FOG) is animportant PET (Positron Emission Tomography) radiopharmaceutical for tumour imaging. In the PETtechnique glucose metabolism in tumour tissues can be determined quantitatively and used for diagnosisstaging and monitoring of treatment tumour or cancer disease in medical oncology. The production of 2eSF)Fluoro-2-0eoxy-O-Glucose ISF -FOG using compact automated system module TRACERlab MXhas been carried out. The modular setup of the apparatus permits reliable for routine synthesis ofradiopharmaceuticals lSF -FOG based on kriptofix mediated nucleophilic tluorination to mannose tritlateprecursor. Radiochemical yield of IsF-FOG was 53.895 % (decay time uncorrected) in 40 minutes. Theproduct showed that the colorless and clear solution at pH:6, sterile and pirogen free, kriptofix impuritieswas low and radiochemical purity was 99.595%.Keywords: PET, radiopharmaceutical, FOG
Partisipasi Masyarakat dalam Pengembangan Objek Wisata Srambang Park (Studi Kasus Wisata Srambang Park) Nimastuti, Erysa; Wibowo, Agung; Lestari, Eny
JIA (Jurnal Ilmiah Agribisnis) : Jurnal Agribisnis dan Ilmu Sosial Ekonomi Pertanian Vol 6, No 4 (2021)
Publisher : Department of Agribusiness, Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37149/jia.v6i4.20308

Abstract

Tourism object is one of the important sectors for the country because it contributes quite a lot of foreign exchange. Tourism objects require management in periodic and sustainable development. The development of regional things cannot be separated from the participation of the community and the government. This study aims to analyze community participation in the development of Srambang Park tourism objects, including community participation in the participation stages, supporting and inhibiting factors of development, motivation to participate, and developing the impact of tourism objects on economic, social environmental aspects. The research method used in this research is descriptive qualitative. The research was conducted on 20-25 May 2021 with seven informants. The research location is in Srambang Park, Girimulyo Village, Paron District, Ngawi Regency. The results of the study indicate that community participation is very active in the development of tourism objects. This activity can be reflected in the community's involvement in the tourist attraction by becoming a motorcycle taxi driver, parking attendant, trader, and employee. Supporting factors include tourist attraction, marketing, infrastructure, and stakeholders. The inhibiting factor for the development of tourism objects is the existence of a pandemic that occurred in early 2020. The motivation of the community to participate in the development of tourism objects is because of the opportunities, desires, and needs. The impact arising from the existence of a tourist attraction is an average positive economic, social and environmental impact.
Farmer’s Motivational Factor on Farmers Managed-Extension Activities (FMA)’S Adoption in Temanggung Regency Ihsaniyati, Hanifah; Setyowati, Nuning; Sutarto, Sutarto; Lestari, Eny
Journal of Rural Indonesia [JORI] Vol. 3 No. 1 (2015)
Publisher : Journal of Rural Indonesia [JORI]

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Abstract

Farmers Managed-Extension Activities (FMA) provides substantial benefits to the farming community empowerment, especially for the improvement of information services for farmers. Consider the benefits and objectives are achieved , then this great program requires rigorous evaluation and mentoring to monitor progress . Previous survey showed no understanding of the diversity of farmers’ level , the percentage decrease in the number of farmers who apply from 2010 (64.56 %) to the year 2011 (48.23 %), and parthnership between farmers and traders only 35.9 % (still small). On the other hand, there is saturation  analysis tools in studies on adoption. Therefore, this study aimed to analyze the motivational factors of farmers against the FMA program. The method used in this research was models the Technology Acceptance Model using Structural Equation Models with analysis tools , namely PLS (Partial Least Square). The results showed (1) Perception of farmers to ease was not significantly related to the attitude of farmers towards FMA at a significance level of 0.43 (p value); (2) Perception of farmers on the benefits / uses significantly associated with attitudes of farmers towards FMA at the 0.01 level (p value), (3) ability to absorb farmers are not significantly related to the attitude of farmers towards FMA at a significance level of 0.48 (p value), (4) the diversity of the media associated significantly with the attitude of farmers towards FMA at the 0.01 signif- icance level (p value), (5) attitude significantly associated with implementing farmers ‘ intentions / FMA adoption at a significance level of 1.90539 E - 08 (p value), (6) intention farmers significantly associated with implementing farmers’ behavior/FMA adoption at a significance level of 3.14341 E - 08 (p value).Keywords : FMA, adoption, farmer,extension, empowerment
Hubungan Antara Aspek Kognitif Sikap Dengan Partisipasi Petani Dalam Pengembangan Kopi Robusta Temanggung Berbasis Indikasi Geografis (IG)(Studi Kasus MPIG-KRT) Saputra, Natan Rio; Lestari, Eny; Widiyanto, Widiyanto
Journal of Integrated Agricultural Socio-Economics and Entrepreneurial Research (JIASEE) Vol 2, No 1 (2023): Volume.2 No.1 Oktober 2023
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jiasee.2.1.2023.35-40

Abstract

Robusta coffee is one of the global agricultural product issues that has developed rapidly. Robusta coffee production has increased in various coffee-producing countries, as well as creating competition among robusta coffee-producing countries. This has an impact on coffee development efforts undertaken. One of the efforts to develop robusta coffee is through Geographical Indications (GI). The existence of Geographical Indications (GI) raises various responses from farmers, including attitude and participation. Attitude and participation are indicators of success in regional commodity development. This study aims to analyze the attitude of farmers in development geographical indication (GI) based on Temanggung robusta coffee;analyze farmer participation in development geographical indication (GI) based on Temanggung robusta coffee;analyze the relationship between attitudes and farmer participation in development Temanggung Robusta Coffee based on Geographical Indication (IG). The basic method used is descriptive quantitative with survey techniques. The results showed 1) cognitive attitudes were in the good category. 2) farmer participation is in the medium and low categories. 3) there is a significant relationship between cognitive aspects and farmer participation
Pemberdayaan Masyarakat Melalui Penguatan Modal Sosial dan Peran Stakeholder dalam Pembangunan Desa Wisata di Kabupaten Karanganyar Wibowo, Agung; Lestari, Eny; Sugihardjo
Jurnal Penyuluhan Vol. 20 No. 01 (2024): Jurnal Penyuluhan
Publisher : Department of Communication and Community Development Sciences and PAPPI (Perhimpunan Ahli Penyuluhan Pembangunan Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25015/20202446684

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Keberadaan nilai-nilai modal sosial dan peran stakeholder dalam pemberdayaan masyarakat di desa wisata memberikan dampak pada penguatan ekonomi lokal. Penelitian ini bertujuan mendeskripsikan nilai-nilai modal sosial dan peran stakeholders dalam pembangunan desa wisata. Lokasi penelitian ini di Kecamatan Ngargoyoso Kabupaten Karanganyar. Penelitian ini menggunakan metode penelitian kualitatif dengan menggunakan desain penelitian fenomenologi. Informan dalam penelitian ini adalah tokoh masyarakat, perangkat desa, petani, kelompok wanita tani, Kelompok usaha ekonomi produktif. Analisis data dilakukan dengan menggunakan model analisis interaktif, yaitu melalui proses pengumpulan data, reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa nilai-nilai modal sosial di masyarakat (hubungan sosial, nilai/norma, toleransi, kesedian mendengar, kejujuran, pengetahuan tradisional, jaringan sosial, trust, tukar kebaikan, kesetiaan dan kebersamaan, tanggung jawab, partisipasi sosial, dan kemandirian) terbukti berperan penting dalam pembangunan desa wisata. Selanjutnya stakeholder (Pemerintah Desa, Perguruan Tinggi, Karang Taruna, PKK (Pembinaan Kesejahteraan Keluarga), tokoh masyarakat, Perhutani) memainkan peran penting di dalam pemberdayaan masyarakat, yakni membangun keberlanjutan, melakukan perubahan dan sebagai fasilitator.
Strategi BUMDes Guyub Rukun dalam Pemberdayaan Masyarakat Desa Wringinputih, Kecamatan Borobudur, Kabupaten Magelang Rachmavianti, Nafiza; Lestari, Eny; Permatasari, Putri
AgriHumanis: Journal of Agriculture and Human Resource Development Studies Vol. 5 No. 1 (2024): AgriHumanis: Journal of Agriculture and Human Resource Development Studies
Publisher : Balai Pelatihan Pertanian Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46575/agrihumanis.v5i1.186

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One of the steps in development to alleviate poverty is the presence of BUMDes. Wringinputih Village is a village in Borobudur District which has a BUMDes named BUMDes Guyub Rukun. The establishment of BUMDes aims to manage the existing potential of the village. This management requires the intensive role of BUMDes Guyub Rukun by optimizing natural resources and human resources through community empowerment so that there will be an increase in terms of community knowledge and skills. The success of community empowerment can be achieved through strategies implemented by BUMDes. The purpose of this study is to analyze the strategy of BUMDes in increasing community empowerment. The basic method of this study is qualitative descriptive by purposively determining informants sampling and snowball sampling. Data collection techniques by means of in-depth interviews, observations, and documentation and using Miles and Huberman's data analysis techniques. Data validity using source triangulation and techniques. The informants in the study were 28 people. The research results show that the strategies used by BUMDes in improving community empowerment are the possibility, strengthening, protection, support, and maintenance. Possible strategies are obervation and socialization to society. The reinforcement strategy is to conduct training and provide modalities. The protection strategy is to provide assistance. The strategy that was carried out was to open a new job field. Maintenance strategies are to conduct evaluation and monitoring.
Pemberdayaan masyarakat melalui inisiasi bank sampah Rusdiyana, Eksa; Sugihardjo; Setyowati, Retno; Widiyanto; Lestari, Eny
Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Vol 7 No 3 (2024)
Publisher : University of Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jipemas.v7i3.21259

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Implementasi prinsip pemilahan sampah reduce, reuse, dan recycle melalui bank sampah belum banyak berkembang di masyarakat. Inisiasi bank sampah masih dihadapkan dengan berbagai kendala seperti literasi ekologi tentang sampah yang masih kurang serta minimnya tenaga penggerak bank sampah itu sendiri. Kegiatan pengabdian masyarakat di Dusun Kepuh ini bertujuan untuk menguatkan literasi ekologi permasalahan sampah serta menginisiasi bank sampah tingkat desa. Metode pendekatan yang digunakan adalah partisipatory rural appraisal (PRA) dengan masyarakat mitra kelompok PKK. Dalam rangka meningkatkan pengetahuan dan sikap mitra terkait literasi sampah digunakan pendekatan kelompok dengan teknik penyuluhan. Materi penyuluhan yang diberikan meliputi: (1) Edukasi masalah sampah, (2) Pemetaan perilaku rumah tangga terhadap sampah, serta (3) Urgensi keberadaan bank sampah. Sedangkan untuk meningkatkan keterampilan pengelolaan bank sampah dilakukan dengan teknik praktek, pendampingan, operasional bank sampah, studi banding, serta monitoring dan evaluasi terhadap keberjalanan program bank sampah. Berdasarkan program yang telah terlaksana, diperoleh hasil yaitu; (1) Berdasarkan peta pemanfaatan sampah, sebagian kecil rumah tangga PKK sudah berupaya memanfaatkan sampah jenis tertentu. (2) Inisiasi bank sampah diharapkan mampu menguatkan perilaku rumah tangga PKK dalam memanfaatkan sampah, hal ini terlihat dari adanya peningkatan partisipasi anggota PKK dalam kegiatan operasional bank sampah, serta para pengurus telah memiliki ketrampilan dalam menjalankan bank sampah.
Strengthening the Capacity to Adapt to Climate Change among Farmers in a Banana Center in Java, Indonesia Wibowo, Agung; Lestari, Eny; Rahayu, Paramita
Komunitas Vol 15, No 2 (2023): September
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/komunitas.v15i2.46577

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Climate change causes basic problems in the lives of farmers in a banana center, such as a decrease in the quality and quantity of bananas. The various impacts of climate change will not cause food insecurity if the community has an adequate adaptive capacity. The purpose of this study is to analyze the capacity of farmers in a banana center to adapt to a change in the quality and quantity of bananas due to climate change. In-depth interviews, observation and focus group discussions were used to collect data. The unit of analysis is at the individual level in society. The data analysis was carried out through the stages of data reduction, data presentation, and drawing a conclusion. The results show that the development of community capacity to maintain the quality and quantity of bananas is carried out by strengthening the capacity of individuals, groups, and institutions that play an important role in adapting to climate change. This has an impact on the collective action of the community to maintain the sustainability of the banana center.
The Influence of Soybean Farmer Characteristics on The Decision To Apply Plant-based Pesticide Technology in Ngaringan District, Grobogan Regency Dewi, Milinia Sari; Lestari, Eny; Rusdiyana, Eksa
West Science Interdisciplinary Studies Vol. 2 No. 10 (2024): West Science Interdisciplinary Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsis.v2i10.1343

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Plant-based pesticides are environmentally friendly and sustainable pest control technologies. However, the awareness of soybean farmers in Ngaringan District, Grobogan Regency to apply plant-based pesticides is still low. The low application of plant-based pesticides is influenced by the characteristics of the farmers. This research aims to identify the characteristics of soybean farmers; identify the stages of decision-making among soybean farmers in applying plant-based pesticide technology; and analyze the influence of soybean farmer characteristics on the decision to apply plant-based pesticides in Ngaringan District, Grobogan Regency. The research uses a quantitative method with a survey technique. The research was carried out purposively in Ngaringan District, with a sample of 70 soybean farmers selected through proportional random sampling techniques. Data analysis was conducted using multiple linear regression tests with IBM SPSS Statistics 25. The results of the research show that the majority of soybean farmers in Ngaringan District are in the early elderly age category, very small land areas, formal education at the high school level, very low non-formal education, highly experienced in soybean farming, and high level of cosmopolitanism; the decision-making process for the application of plant-based pesticide technology is categorized as high at the knowledge and persuasion stages, while at the decision, implementation, and confirmation stages, it is categorized as very low; and the farmer characteristics of land area and non-formal education have a significant effect on the decision to apply plant-based pesticides, while age, formal education, farming experience, and cosmopolitanism do not have a significant effect.
Pemberdayaan Kelompok Tani melalui Hilirisasi Tanaman Kopi di Kabupaten Magetan Wibowo, Agung; Suwarto, Suwarto; Lestari, Eny
Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Vol 7, No 4 (2024): Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstormin
Publisher : Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/japhb.v7i4.7186

Abstract

Kegiatan Program Kemitraaan Masyarakat ini difokuskan pada Kelompok Tani Makmur di dalam merintis hilirisasi komoditas kopi sejalan dengan pengembangan desa wisata, dengan beberapa pertimbangan: (1) dari aspek manajemen, masih sangat minimnya pengetahuan manajemen dalam mengelola kelompok; (2) dari aspek ekonomi, pemasaran kopi belum mengggembirakan sejalan dengan maraknya pembangunan desa wisata; (3) Desa Plangkrongan belum dikenal luas di luar wilayah kabupaten padahal wilayah tersebut potensial untuk menjadi destinasi wilayah yang dekat dengan Telaga Sarangan.  Beberapa permasalahan yang dihadapi oleh anggota kelompok tani Makmr adalah: (1) masalah mesin pengolahan yang masih sederhana; (2) masalah pemasaran produk yang hanya berkisar di wilayah lokal.Tujuan kegiana ini adalah: (1) memecahkan pemecahan permasalahan di bidang produksi hilirisasi pengolahan kopi; (2) memecahkan permasalahan di bidang manajemen pada pelaku UMKM hilirasi pengolahan kopi; (3) memecahkan permasalahan di bidang promosi dan pemasaran pada pelaku UMKM hilirisasi pengolahan kopi. Metode pemecahan permasalahan yang diterapkan adalah: (1) identifikasi karakteristik dan kebutuhan pengrajin olahan kopi akan informasi bisnis; (2) sosialisasi tentang pentingnya kelembagaan usaha agar bisa membangun kemitraan usaha dengan stakeholder; (3) pendampingan kepada para pengrajin olahan kopi dalam mengakses informasi bisnis untuk menuju pengembangan kawasan sentra. Kegiatan tersebut dilakukan dengan Focus Group Discussion dan teknik Partisipatory Rural Apraisal. Hasil pengabdian melipiuti pemnecahan permasalhanan di bidang produksi, pemecahan masalah di bidang di bidang manajmen pada pelaku UMKM, dan pemecahan permasalahan di bidang promosi dan pemasaran. Meskipun menghadapi berbagai tantangan, upaya bersama dari berbagai pihak dapat memastikan keberlanjutan dan keberhasilan hilirisasi tanaman kopi di Kabupaten Magetan, sehingga mampu memberikan manfaat yang lebih besar bagi petani dan komunitas sekitarnya.