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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Althea Medical Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Berkala Kedokteran Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Jurnal Ners Respiratory Science Jurnal Indonesia Sosial Teknologi
Haryati Haryati
Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine Lambung Mangkurat University, Ulin Regional Hospital, Banjarmasin
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Effect of Omega-3 Addition on Sputum Conversion, Body Mass Index, Interleukin-6, and Lymphocyte Monocyte Ratio in the Treatment of Pulmonary Tuberculosis Ferryansyah Ferryansyah; Mohamad Isa; Juhairina Juhairina; Haryati Haryati; Ali Assagaf; Erna Kusumawardhani
Jurnal Indonesia Sosial Teknologi Vol. 6 No. 3 (2025): Jurnal Indonesia Sosial Teknologi
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jist.v6i3.7050

Abstract

This research aims to investigate the impact of omega-3 supplementation on sputum conversion, body mass index (BMI), interleukin-6 (IL-6) levels, and lymphocyte-monocyte ratio (LMR) in patients with pulmonary tuberculosis (TB). Tuberculosis is a significant health problem in Indonesia, with high incidence and mortality rates. Omega-3 fatty acids are known to have anti-inflammatory effects and may enhance the immune response, potentially supporting tuberculosis (TB) therapy. The research methods included bacteriological examination of the sputum, measurement of BMI, IL-6 levels, and MLR in patients who received additional Omega-3 compared to the control group. The results are expected to provide an overview of the effectiveness of Omega-3 as a supportive therapy in treating TB, as well as its contribution to improving patients' nutritional status and immune response. This research is expected to serve as a reference for developing more effective and affordable tuberculosis therapies.
Adjunctive Effects of Bajakah Wood (Spatholobus littoralis Hassk.) on Cholesterol and Triglyceride in EGFR Wild Type Lung Adenocarcinoma Patients Elok Hikmatun Nikmah; Erna Kusumawardhani; Eko Suhartono; Ira Nurrasyidah; Isa Ansori; Ali Assagaf; Mohamad Isa; Haryati Haryati; Ika Kustiyah Oktaviyanti
Jurnal Respirasi Vol. 12 No. 1 (2026): January 2026
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v12-I.1.2026.13-19

Abstract

Introduction: Lung cancer is the leading cause of cancer mortality, influenced by uncontrolled cell proliferation, migration, metastasis, and mutations. The imbalance of high-density lipoprotein (HDL) and triglycerides (TG) has an important role. Spatholobus littoralis Hassk., or Bajakah wood, has antioxidant effects due to dihydrokaempferol, which lowers cholesterol levels and increases HDL. This additional therapy is expected to have a positive impact, supporting treatment for patients with wild-type lung adenocarcinoma. Methods: This was a single-blind clinical trial conducted at Ulin General Hospital, Banjarmasin, Indonesia, in patients with epidermal growth factor receptor (EGFR)-wild-type lung adenocarcinoma at a minimum stage IIIA, from June 2023 to July 2024. The participants were divided into two groups: the treatment group (adjunctive Bajakah wood 1,000 mg) and the control group. Cholesterol, low-density lipoprotein (LDL), HDL, and TG were measured twice before starting chemotherapy and after the third chemotherapy cycle. The resulting data were analyzed using the independent t-test and the Mann-Whitney test through the Statistical Package for the Social Sciences (SPSS) version 26. Results: For the 21 total patients, the cholesterol and TG levels in the treatment group before and after the third chemotherapy were 200.55±42.65 to 184.45±24.20 and 131.27±44.76 to 112.73±34.74, respectively. The control group results were 185.10±51.98 to 168.30±32.89 and 118.30±51.30 to 104.10±12.53, respectively. The comparison of changes between the two groups was not significant (p-value > 0.005). Conclusion: Cholesterol and TG levels were reduced, but there were no statistically significant differences after the addition of therapy with Bajakah wood.
Co-Authors Aida Hastuti Ali Assagaf Ali Assagaf Ali Assagaf Ana Rima Andreas Infianto Anggarda Kristianti Utomo Anisa Anisa Arganita, Fidya Rahmadhany Arif Santoso Ayudiah Puspita Mayasari Ayudiah Puspita Mayasari Brian Pramana Santoso Desi Rahmawaty Desi Rahmawaty Desi Rahmawaty Dimas Satrio Baringgo Dwi Laksono Adi Putro Eko Suhartono Eko Suhartono Eko Suhartono Elisna Syahruddin Elok Hikmatun Nikmah Elok Hikmatun Nikmah Emmi Erliyanti Ermayanti, Sabrina Erna Kusumawardhani Erna Kusumawardhani Farida Heriyani Ferry Dwi Kurniawan Ferryansyah Ferryansyah Fidya Rahmadhany Arganita Gusti Muhammad Perdana Putera Hapsari Lintang Sekartaji Holly Diany Ida Ayu Jasminarti Ika Kustiyah Oktaviyanti Ira Nurrasyidah Ira Nurrasyidah Isa Ansori Iskandar Iskandar Joharman Joharman Juhairina Juhairina Laksmi Wulandari Marsheilla Riska Moh. Isa Mohamad Isa Mohamad Isa Muhammad Nor Nathaniel Aditya Nida Amalia Nila Nirmalasari Noni Novisari Soeroso Noor Athiyya Sabrina Wahda Utami Setyawan, Ungky Agus Sita Andarini Sri Melati Munir Tenri Ashari Wanahari Widya Ramadhaniati Widya Ramadhaniati Zaini, Jamal