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Hubungan Parameter Laboratorium dengan Derajat Klinis COVID-19 pada Kehamilan Nirmalasari, Rully Ayu; Surjadi, Lily Marliany; Maharani, Laksmi; Lisnawati, Yuyun; Mangun, Dhea
Jurnal Biomedika dan Kesehatan Vol 6 No 3 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.291-299

Abstract

Background Pregnant women were one of the most susceptible groups because they are vulnerable to respiratory infection. They may get more severe symptoms due to their physiological changes during pregnancy including the immunological response. This study was performed to find whether there is an association between laboratory parameters (Hb, leukocytes, platelet, neutrophils, lymphocyte, monocyte, NLR, PLR and CRP) and the severity of Covid-19 infection in pregnant women. Methods This study is a retrospective cohort study using secondary data from patient’s medical records at Persahabatan General Hospital, Jakarta from March to June 2021. Results Pregnancy cases with COVID-19 in this study were in the mean of 29 year age. Most of them are in the third trimester of pregnancy. 80.5% from 67 patients have no- mild symptom while 19.5% have moderate to severe symptom. There are no difference in vital sign nor oxygen saturation at first admission. Lower level was found in the parameter of leukocyte, lymphocyte and monocyte.  Neutrophil, neutrophil-to-lymphocyte ratio and C-reactive Protein increase as the degree of severity increase.  The mean neutrophil in pregnant women with moderate to severe COVID-19 symptom was 80.49±7.47 while median NLR value was of 6.76 (2.73-18.71) . Conclusions Neutrophil, neutrophil-to-lymphocyte ratio and C-reactive Protein has associate significantly to severity symtomps of COVID-19 in pregnancy.
Kejadian Solusio Plasenta tanpa Rasa Nyeri dengan Perdarahan Retroplasenta 80%: Laporan Kasus Mayasari, Atut Cicih; Abikusno, Nugroho; Maharani, Laksmi; Wratsangka, Raditya
Jurnal Biomedika dan Kesehatan Vol 7 No 1 (2024)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2024.v7.91-97

Abstract

The maternal mortality rate in Indonesia is still high. According to the Indonesian Household Health Survey (SKRT) in 2001 found that bleeding  in pregnancy contributes as the main cause of maternal mortality. Antepartum hemorrhage can be caused by placental abruption (PA) and placenta previa. This bleeding condition is an emergency case because it threatens the lives of both mother and  fetus (mother-fetal dyad). Placental abruption is usually accompanied by pain due to continuous uterine contractions. In this case, although concealed hematoma exists in almost 80% of PA cases, the mother shows no sign or symptom even though the fetus is severely at risk. This condition can cause delayed management that leads to mother and fetal mortality, known as asymptomatic placental abruption.
Penyuluhan Apakah Kanker Serviks Itu Pada Ibu Dan Remaja Putri Di Desa Nagrak - Ciangsana, Bogor. Cicih Mayasari, Atut; Marliany Surjadi, Lily; Maharani, Laksmi; Yastani, Deasyka
AMMA : Jurnal Pengabdian Masyarakat Vol. 5 No. 1 : Februari (2026): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cervical cancer is the second leading cause of death in women. Yet, cervical cancer is preventable because it is caused by the Human Papilloma Virus (HPV), which, if infected, can take decades to develop into cancer. Cervical cancer prevention efforts have not yet reached their target. Coverage remains low. Knowledge about cervical cancer itself is still lacking, as is prevention. The perceived discomfort of early detection tests makes women reluctant to undergo them. Therefore, education about cervical cancer is needed to increase knowledge and thus increase the coverage of early detection tests. The ultimate goal is to reduce the incidence and mortality caused by cervical cancer. To this end, education about cervical cancer is being conducted for women, namely mothers and young girls, especially in the villages of Nagrak and Ciangsana, Bogor.
HUBUNGAN ANTARA DIABETES MELITUS DAN INFEKSI SALURAN KEMIH DI RSUD BUDHI ASIH Masyitah, Reza Julysha; Maharani, Laksmi
Jurnal Kesehatan Tambusai Vol. 7 No. 1 (2026): MARET 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v7i1.55011

Abstract

Infeksi Saluran Kemih (ISK) merupakan salah satu infeksi yang paling sering dijumpai secara global dan berkontribusi terhadap peningkatan morbiditas, terutama pada kelompok berisiko tinggi seperti pasien Diabetes Melitus (DM). Kondisi hiperglikemia pada DM dapat menurunkan sistem imun dan mempermudah kolonisasi bakteri pada saluran kemih, sehingga berhubungan dengan terjadinya ISK. Penelitian ini bertujuan untuk mengetahui hubungan antara Diabetes Melitus dan kejadian Infeksi Saluran Kemih di RSUD Budhi Asih. Penelitian ini menggunakan desain analitik observasional dengan pendekatan cross-sectional. Populasi penelitian adalah pasien rawat jalan dan rawat inap di RSUD Budhi Asih yang memenuhi periode penelitian. Sampel penelitian berjumlah 187 pasien yang memenuhi kriteria inklusi, dengan metode non-probability sampling menggunakan teknik consecutive sampling. Data sekunder diperoleh dari rekam medis dan hasil pemeriksaan laboratorium. Variabel bebas dalam penelitian ini adalah Diabetes Melitus, sedangkan variabel terikat adalah Infeksi Saluran Kemih. Analisis data dilakukan secara bivariat menggunakan uji chi-square dengan tingkat kemaknaan α=0,05. Hasil penelitian menunjukkan bahwa 98 responden (52,4%) menderita Diabetes Melitus dan 48 responden (25,7%) mengalami Infeksi Saluran Kemih. Proporsi kejadian ISK lebih tinggi pada pasien dengan Diabetes Melitus dibandingkan pasien tanpa Diabetes Melitus. Hasil uji chi-square menunjukkan nilai p=0,000, yang menunjukkan bahwa terdapat hubungan yang signifikan antara Diabetes Melitus dan kejadian Infeksi Saluran Kemih di RSUD Budhi Asih.