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All Journal e-GIGI Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Padjadjaran Journal of Dental Researchers and Students JITEKGI Jurnal Ilmiah dan Teknologi Kedokteran Gigi
Silvi Kintawati
Department Of Oral Biology, Faculty Of Dentistry, Universitas Padjadjaran
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Hubungan indeks massa tubuh (IMT) dan laju aliran saliva pada mahasiswa preklinik angkatan 2014-2016 Fakultas Kedokteran Gigi Universitas PadjadjaranRelationship between body mass index (BMI) and salivary flow rate amongst pre-clinical students of Faculty of Dentistry Universitas Padjadjaran batch 2014-2016 Inviolita Annissa Muttaqien; Silvi Kintawati; Ervin Rizali
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 29, No 2 (2017): Agustus
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (351.061 KB) | DOI: 10.24198/jkg.v29i2.18571

Abstract

Pendahuluan: Saliva merupakan cairan yang sangat penting terkait dengan proses biologis di dalam rongga mulut. Laju aliran saliva merupakan salah satu indikator saliva yang berpengaruh terhadap pembentukan lesi karies maupun penyakit mulut. Laju aliran saliva dipengaruhi oleh berbagai macam faktor, salah satunya yaitu gizi. Salah satu parameter status gizi yaitu Indeks Massa Tubuh (IMT). Tujuan penelitian ini adalah untuk mengetahui apakah terdapat hubungan antara Indeks Massa Tubuh (IMT) dengan laju aliran saliva pada mahasiswa preklinik angkatan 2014-2016 Fakultas Kedokteran Gigi Universitas Padjadjaran. Metode: Jenis penelitian yang digunakan adalah deskriptif analitik. Pengambilan sampel penelitian menggunakan purposive random sampling. Sampel penelitian yang didapatkan berjumlah 90 individu yang terdiri dari 71 perempuan dan 19 laki-laki. Penelitian dilakukan dengan mengukur berat badan serta tinggi badan untuk mendapatkan nilai IMT, kemudian dilanjutkan pengukuran laju aliran saliva. Data dianalisis menggunakan uji korelasi Pearson. Hasil: Hasil uji statistik menunjukkan tidak adanya relasi signifikan antara Indeks Massa Tubuh (IMT) dengan laju aliran saliva baik pada mahasiswa perempuan maupun laki-laki, dikarenakan adanya faktor-faktor penentu lainnya. Simpulan: Indeks Massa Tubuh (IMT) tidak memiliki pengaruh yang bermakna terhadap laju aliran saliva pada mahasiswa preklinik angkatan 2014-2016 Fakultas Kedokteran Gigi Universitas Padjadjaran.Kata kunci: Indeks Massa Tubuh (IMT), laju aliran saliva. ABSTRACTIntroduction: Saliva is a very important liquid related to biological processes in the oral cavity. Salivary flow rate is one indicator of saliva which affects the formation of caries lesions and oral diseases. Salivary flow rate is influenced by various factors, one of which is nutrition. One of the nutritional status parameters is the Body Mass Index (BMI). The purpose of this study was to determine whether there was a relationship between Body Mass Index (BMI) and salivary flow rate in 2014-2016 pre-clinical students at the Faculty of Dentistry, Padjadjaran University. Methods: The type of research used is descriptive analytic. The research sample was taken using purposive random sampling. The research sample obtained was 90 individuals consisting of 71 women and 19 men. The study was conducted by measuring body weight and height to obtain BMI values, then continued measurement of salivary flow rate. Data were analyzed using Pearson correlation test. Result: The results of statistical tests showed no significant relationship between Body Mass Index (BMI) and salivary flow rate in both male and female students, due to other determinants. Conclusion: Body Mass Index (BMI) does not have a significant effect on salivary flow rate in 2014-2016 pre-clinical students at the Faculty of Dentistry, Padjadjaran University.Keywords: Body Mass Index (BMI), salivary flow rate.
Perbedaan pH saliva antara wanita hamil dan tidak hamilThe difference of salivary pH in pregnant and non-pregnant women Inas Sania Afanina Habib; Rosiliwati Wihardja; Silvi Kintawati
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 31, No 1 (2019): April 2019
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (351.293 KB) | DOI: 10.24198/jkg.v31i1.17234

Abstract

Pendahuluan: Saliva merupakan cairan mulut yang terdiri atas komponen organik dan anorganik dan berperan penting dalam lingkungan rongga mulut. Kehamilan dapat mempengaruhi saliva, salah satunya berpengaruh pada pH saliva. Wanita hamil biasanya mengeluhkan mulut terasa asam. Penelitian ini bertujuan untuk mengetahui perbedaan pH saliva antara wanita hamil dan tidak hamil di Puskesmas Jatinangor. Metode: Penelitian ini bersifat observasi dengan desain analitik. Subjek penelitian terdiri atas 30 wanita hamil dan 30 wanita tidak hamil yang dipilih dengan metode purposive sampling yang berada di Puskesmas Jatinangor. Unstimulated saliva dikumpulkan untuk menentukan nilai pH saliva. Data dianalisis dengan independent two sample t-test dengan α = 0,05. Hasil: Hasil penelitian menunjukkan nilai signifikansi 0,000 (p<0,01). pH saliva wanita hamil lebih rendah daripada pH saliva wanita tidak hamil dengan rata-rata pH saliva wanita hamil 6,519 dan rata-rata pH saliva wanita tidak hamil 7,192. Penurunan pH saliva terjadi karena peningkatan kadar hormon progesteron yang menyebabkan penurunan konsentrasi ion bikarbonat (HCO3-), dan peningkatan enzim amilase, serta seringnya wanita hamil mengonsumsi makanan manis dan/atau asam. Simpulan: Terdapat perbedaan pH saliva antara wanita hamil dan tidak hamil, dimana pH saliva wanita hamil lebih rendah daripada pH saliva wanita tidak hamil.Kata kunci: Kehamilan, pH saliva, unstimulated saliva. ABSTRACTIntroduction: Saliva is an oral fluid consisting of organic and inorganic components which plays an essential role in the oral environment. Pregnancy can affect saliva, one of which affects the pH of saliva. Pregnant women usually complain that their mouth feels sour. This study was aimed to determine the difference in salivary pH between pregnant and non-pregnant women at Jatinangor Community Health Centre. Methods: This research was observational with analytic design. The research subjects consisted of 30 pregnant women and 30 non-pregnant women who were selected by the purposive sampling method at Jatinangor Community Health Center. Unstimulated saliva was collected to determine the pH value of saliva. Data were analysed by independent two-sample t-test with α = 0.05. Result: The results of the study showed a significance value of 0.000 (p < 0.01). The salivary pH of pregnant woman was lower than the salivary pH of non-pregnant woman with an average salivary pH of 6.519 for pregnant woman and an average salivary pH of 7,192 for non-pregnant woman. A decrease in salivary pH occurred because of an increase in the level of the progesterone hormone which also causes a decrease in the concentration of bicarbonate ions (HCO3-), and an increase in amylase enzymes, and the frequency of pregnant women consuming sweet and sour foods. Conclusion: There was a difference in the salivary pH between pregnant and non-pregnant women as indicated by the salivary pH of pregnant women which was lower than the salivary pH of non-pregnant women.Keywords: Pregnancy, salivary pH, unstimulated saliva.
Kualitas hidup pasien dengan inflamasi mukosa mulut stomatitis aftosa rekurenQuality of life of patients with oral mucosal inflammation recurrent aphthous stomatitis Lena Noviana; Silvi Kintawati; Sri Susilawati
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 30, No 1 (2018): April
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (363.065 KB) | DOI: 10.24198/jkg.v30i1.18191

Abstract

Pendahuluan: Inflamasi mukosa mulut stomatitis aftosa rekuren (SAR) dapat berdampak pada fungsi pengunyahan, penelanan dan bicara, sehingga akan mempengaruhi status gizi serta kualitas hidup. Tujuan penelitian ini adalah untuk mendapatkan gambaran kualitas hidup pasien dengan SAR di Rumah Sakit Gigi dan Mulut (RSGM) Universitas Padjadjaran (Unpad). Metode: Jenis penelitian yang digunakan deskriptif dengan jumlah responden 32 pasien SAR di RSGM Unpad. Kuesioner yang diisi oleh responden diadaptasi dari WHO STEPWise Approach to Surveillance – Oral Health Module tahun 2001. Hasil: Kualitas hidup pasien dengan inflamasi mukosa mulut (SAR) di RSGM Unpad adalah 43,8%, dengan rincian 33,6% untuk dimensi fungsi, 19,8% untuk dimensi psikologis, 21,9% untuk dimensi sosial, dan 100% untuk dimensi nyeri. Simpulan: Kualitas hidup pasien dengan stomatitis aftosa rekuren (SAR) di RSGM Unpad cukup berdampak pada dimensi fungsi, kurang berdampak pada dimensi psikologis dan sosial dan sangat berdampak pada dimensi nyeri.Kata kunci: Inflamasi mukosa mulut, kualitas hidup, stomatitis aftosa rekuren. ABSTRACTIntroduction: Oral mucosal inflammation recurrent aphthous stomatitis (RAS) will affect the function of mastication, ingestion, and speech, thus also affecting the nutritional status and quality of life. The purpose of this research was to find out the quality of life patients with RAS in Universitas Padjadjaran Dental Hospital. Methods: This research used descriptive methods with respondents of 32 patients with RAS in Universitas Padjadjaran Dental Hospital. A questionnaire adapted from WHO STEPWise Approach to Surveillance–Oral Health Module 2001 was filled out by respondents. Result: The results indicated that the quality of life of patients with RAS in Universitas Padjadjaran Dental Hospital was 43.8%, consisted of 33.6% for functional dimension, 19.8% for psychological dimension, 21.9% for social dimension, and 100% for pain dimension. Conclusion: Quality of life of patients with recurrent aphthous stomatitis (RAS) in Universitas Padjadjaran Dental Hospital was quite affected in functional dimension, less affected in psychological dimension, and very affected in pain dimension.Keywords: Oral mucosal inflammation, quality of life, recurrent aphthous stomatitis.
Immunodetection of EGF-receptor, C-erbB oncogenes and HSV-1 antigene in oral mucosal swab preparation from Kretek (Clove cigarette) smokers Silvi Kintawati
Padjadjaran Journal of Dentistry Vol 20, No 2 (2008): July 2008
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1196.946 KB) | DOI: 10.24198/pjd.vol20no2.14141

Abstract

Smoking is the biggest factor for oral cavity malignancy. An oral cavity mucous swab was performed to 30 smokers (mild, moderate and severe) and 10 non-smokers which were followed by immunocytochemistry smear using the antibody for EGF-R, c-erbB, and HSV-1 antigens to reveal the effect of smoking on the occurrence of oral cavity malignancy. The results from this experiment are analyzed statistically using one-way Anava. It is discovered that based on the assessment of the expression level towards EGF-R, and C-erbB oncogene there is a very significant difference between the smoker group and non-smoker group (p < 0.01). Meanwhile, the results from the assessment towards HSV-1 oncogene do not show significant differences between the smoker group (mild, moderate and severe) and the non-smoker group (p > 0.05). The results of this study show that the more a person smokes, the higher possibility of oral cavity malignancy and that the antibody for EGF-R and c-erbB can be used as a marker for early detection of oral cavity malignancy caused by smoking.
GAMBARAN TINGKAT PENGETAHUAN MASYARAKAT TENTANG MEROKOK SEBAGAI FAKTOR RISIKO KANKER RONGGA MULUT DI KELURAHAN BINTAUNA KECAMATAN BINTAUNA KABUPATEN BOLMONG UTARA PROVINSI SULAWESI UTARA Billy Kolintama; Shelly Lelyana; Silvi Kintawati
Jurnal Ilmiah dan Teknologi Kedokteran Gigi Vol 18, No 1 (2022)
Publisher : Fakultas Kedokteran Gigi Universitas Prof. Dr. Moestopo (Beragama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32509/jitekgi.v18i1.1619

Abstract

Latar belakang: kanker rongga mulut merupakan keganasan pada rongga mulut dan penyebab kematian paling umum pada laki-laki maupun perempuan dewasa. Merokok merupakan salah satu faktor risiko kanker rongga mulut terbesar. Risiko terkena kanker rongga mulut tiga kali lebih tinggi pada perokok dibandingkan dengan yang bukan perokok. Pengetahuan berpengaruh terhadap sikap seseorang tentang merokok. Pengetahuan yang kurang akan bahaya rokok cenderung menyebabkan seseorang merokok dan memberikan dampak untuk tetap merokok, karena merokok dianggap tidak menimbulkan risiko bagi kesehatan. Tujuan: untuk mengetahui tingkat pengetahuan masyarakat tentang merokok sebagai faktor risiko kanker rongga mulut. Metode : cross sectional deskriptif observasional dan pengumpulan data melalui cara survey dengan memberikan kuesioner kepada subjek. Penelitian dilakukan pada penduduk Kelurahan Bintauna Kecamatan Bintauna Kabupaten Bolmong Utara Provinsi Sulawesi Utara. Total responden adalah 187 orang yang terdiri dari 101 responden laki-laki dan 86 responden perempuan dengan rentang usia 20-60 tahun. Perolehan data menggunakan kuesioner yang dilakukan dengan wawancara. Hasil : 62% responden memiliki pengetahuan yang baik mengenai merokok sebagai faktor risiko kanker rongga mulut. Kesimpulan: tingkat pengetahuan masyarakat tentang merokok sebagai faktor risiko kanker rongga mulut di Kelurahan Bintauna, secara keseluruhan sudah baik, sedangkan jika dilihat dari perokok dan bukan perokoknya terlihat bahwa responden yang bukan perokok cenderung memiliki pengetahuan yang lebih baik dibandingkan dengan responden perokok.
Potency of Young Coconut Water as a Mouthwash to Saliva pH and Flow Rate in Smokers Yunita P. D. Nurazizah; Dian Lesmana; Silvi Kintawati
e-GiGi Vol. 10 No. 2 (2022): e-GiGi
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/eg.v10i2.44279

Abstract

Abstract: Smoking causes harmful effects on health, especially the oral cavity. However, the oral cavity has saliva as a defence system that can eliminate harmful substances from the body. Normally saliva secreted by the salivary glands has a pH of 6.7-7.4 while in smokers the pH tends to be more acidic. This study aimed to determine the potential of coconut water as a natural mouthwash on the pH and salivary flow in smokers. This was a literature review study by searching scientific journals in Indonesian and English from 2019-2020 through search engines at SINTA, PubMed, and Google Scholar. The keywords used were young coconut water, gargling, cigarette, salivary flow rate, smoking, and salivary pH. The results obtained 17 suitable articles. Individuals who smoked more than 10 cigarettes/day, more than 6 years could have decreased pH and salivary flow. Therefore, coconut water was needed to reduce its effect, which was believed could increase pH and salivary flow. Coconut water had a pH that was almost the same as normal pH of saliva, which was 7.3. Coconut water contained tannins which gave a bitter taste, therefore, it stimulated salivary secretion and increased pH and salivary flow. In conclusion, young coconut water has a pH which is similar with normal saliva, therefore, it could become a natural potential mouthwash to increase pH and salivary flow in smokers. Keywords: young coconut water; mouthwash; salivary flow rate; smoking; salivary pH Abstrak: Merokok memberikan efek berbahaya bagi kesehatan terutama rongga mulut karena mengandung kurang lebih 5000 bahan kimia yang berbahaya. Rongga mulut memiliki saliva sebagai sistem pertahanan yang dapat mengeliminasi zat berbahaya dari tubuh. Cairan saliva disekresikan oleh kelenjar saliva 0,5-1,5 liter/hari dengan pH 6,7-7,4 sedangkan pH pada perokok cenderung lebih asam. Penelitian ini bertujuan untuk mengetahui potensi air kelapa sebagai cairan kumur alami terhadap pH dan aliran saliva perokok. Metode penelitian berupa literature review dengan mencari jurnal ilmiah berbahasa Indonesia dan Inggris dari tahun 2019-2020 melalui mesin pencarian di SINTA, PubMed, dan google scholar dengan kata kunci: air kelapa muda, berkumur, laju aliran saliva, merokok, pH saliva, rokok. Hasil pencarian mendapatkan 17 artikel yang sesuai. Individu yang merokok lebih dari 10 batang/hari lebih dari enam tahun dapat mengalami penurunan pH dan aliran saliva. Dibutuhkan upaya untuk menguranginya, salah satunya dengan berkumur menggunakan air kelapa, yang diyakini dapat meningkatkan pH dan aliran saliva. Hal ini terjadi karena air kelapa memiliki pH yang sama seperti pH normal yaitu 7,3. Air kelapa mengandung tannin yang memberikan rasa pahit sehingga merangsang sekresi saliva yang dapat meningkatkan pH dan aliran saliva. Simpulan penelitian ini ialah air kelapa mempunyai pH mendekati pH saliva normal sehingga dapat menjadi potensi alami untuk meningkatkan pH dan laju aliran saliva pada perokok. Kata kunci: air kelapa muda; berkumur; laju aliran saliva; merokok; pH saliva
Immunoexpression of Ki-67 in determining prognosis of oral cavity squamous cell carcinoma Kintawati, Silvi; Pramesti, Hening Tjaturina
Padjadjaran Journal of Dentistry Vol 31, No 2 (2019): July 2019
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol31no2.22888

Abstract

Introduction: Several researchers have been stated that the right prognosis of oral squamous cell carcinoma (OSCC) can be achieved through assessment of tumor clinical staging and tumor histopathological grading as well. The use of biomarker in histopathological grading is obviously helpful to ensure the prognosis. Objective of this study was to determine the correlation between expression of Ki-67 and histopathological grading of OSCC. Methods: A retrospective study was conducted by assessing 20 cases of paraffin-embedded OSCC derived from the Department of Pathology Anatomy of Hasan Sadikin Hospital Bandung in 2013. The OSCC performing was stained by hematoxylin-eosin. While, antibodies Ki-67 was used in immunohistochemistry reaction to determine the relation of expression of Ki-67 with histopathologic grade of OSCC for predicting a prognosis. Results: The result show that distribution of Ki-67 expression were vary from 20% to 80% in each case. Ki-67 intensity was also distributed from weak, moderate and strong. Conclusion: There is a significant correlation between Ki-67 immunoexpression and the histopathological grading of squamous cell carcinoma (p < 0.01), thus, Ki-67 can be used to predict a prognosis.Keywords: Immunoexpression, Ki-67, prognosis, oral cavity squamous cell carcinoma
The difference of blood pressure before and after consuming Green Kiwi (Actinidia deliciosa) in the young adult group Lesmana, Dian; Rizali, Ervin; Kintawati, Silvi
Padjadjaran Journal of Dentistry Vol 25, No 3 (2013): November 2013
Publisher : Faculty of Dentistry Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol25no3.26808

Abstract

Introduction: Green Kiwi fruit (Actinidia deliciosa) has a lot of nutritional content, one of them is potassium. Potassium helps maintain osmotic pressure in intracellular fluid, protect body’s electrolyte balance, regulate heartbeat, maintain muscle and nerve cell function, reduce the risk of stroke and heart disesase, and decrease blood pressure. Methods: This study is an experimental research, using pair t-test measurement to analize the difference of blood pressure before and after consuming Green Kiwi fruit (Actinidia deliciosa) in early adulthod. The sample are thirty five students of Faculty of Dentistry, Padjadjaran. The number of green kiwi fruit is consume as much as 1 fruits or 150 grams. Blood pressure measured by sphygmomanometer with auscultatory-palpation method. Results: The result of this study shows the averaged blood pressure before and after consuming green kiwi fruit Is 99,543/68,438 mmHg and 97,581/66,743mmHg. Conclusion: The conclusion of the study indicates the existence of difference in blood pressure before and after consuming Green Kiwi fruit (Actinidia deliciosa) in early adulthood (p<5%).
Relationship between filter cigarettes smoking habits with the appearance of smoker’s melanosis (Observation of smoking duration and the amount of cigarettes consumption) Akbar, Rizal Rizky; Widyaputra, Sunardhi; Kintawati, Silvi
Padjadjaran Journal of Dentistry Vol 26, No 2 (2014): July 2014
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol26no2.26698

Abstract

Introduction: Smoking is one of bad habits that are difficult to abandon. Cigarettes contain more than 59 known carcinogenic substances. Cigarettes also contain some metal components and free radicals. Cigarettes consist of several types, one of which is cigarettes filter, which is the most frequently consumed cigarettes. One of the adverse effects of cigarette smoker’s melanosis is a pigmentation disorder that appears in oral cavity. The study aims to look at the relationship between smoking habits of filter’s smoker with appearance of smoker’s melanosis. Methods: This was a descriptive analytic with chi-square test to analyze the relationship between smoking in filter smokers with appearance of smoker’s melanosis. The samples were 90 students of the Faculty of Geology University of Padjadjaran. The smokers who have the criteria of the sample are examined to see the oral condition whether there is a melanosis lesion or not. Results: The result showed an association between smoking habit in filter smokers with the onset of smokers melanosis that observe through the duration of smoking and the amount of cigarettes consumption. Conclusion: There is a relationship between smoking habits in filter smokers and the onset of smoker’s melanosis in terms of smoking duration and the number of cigarettes consumed.
The difference of salivary pH before and after toothbrushing with toothpaste containing Betel leaf (Piper Betle) Fu, Soo Ling; Kintawati, Silvi; Tjahajawati, Sri
Padjadjaran Journal of Dentistry Vol 26, No 3 (2014): November 2014
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (159.05 KB) | DOI: 10.24198/pjd.vol26no3.14012

Abstract

There has been a long history of the use of plants to improve dental health and oral hygiene. The purpose of this research was to find out the difference of salivary pH before and after toothbrushing with toothpaste containing betel leaf (Piper betel). The type of research used was quasi-experimental. Data collected were analyzed by using a paired t-test. The result shows that there is an increase of salivary pH by an average of 0.48 after toothbrushing with toothpaste containing betel leaf (Piper betel). In conclusion, there is the difference between the salivary pH before and after toothbrushing with toothpaste containing betel leaf (Piper betel).
Co-Authors Akbar, Rizal Rizky Anthony Hartanto, Anthony Billy Kolintama Dian Lesmana Ervin Rizali Hening Tjaturina Pramesti Inas Sania Afanina Habib Indah Dwitasari Inviolita Annissa Muttaqien Lelyana, Shelly Lena Noviana Lesmana, Dian Murnisari Dardjan, Murnisari Murnisari Darjan Muttaqien, Inviolita Annissa Noviana, Lena Rizali, Ervin Rizali, Ervin Rosiliwati Wihardja Rosiliwati Wihardja Santosa, Agustine H. Soo Ling Fu, Soo Ling Sri Susilawati Sri Tjahajawati, Sri Sunardhi Widyaputra Vinna K. Sugiaman Winny Yohana, Winny Yunita P. D. Nurazizah