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All Journal International Journal of Electrical and Computer Engineering TEKNIK INFORMATIKA Jurnal Simetris Bulletin of Electrical Engineering and Informatics Explore: Jurnal Sistem Informasi dan Telematika (Telekomunikasi, Multimedia dan Informatika) Jurnal Pengabdian Kepada Masyarakat Sakai Sambayan Jurnas Nasional Teknologi dan Sistem Informasi WARTA KLIK (Kumpulan jurnaL Ilmu Komputer) (e-Journal) Science and Technology Indonesia JOIV : International Journal on Informatics Visualization INTENSIF: Jurnal Ilmiah Penelitian dan Penerapan Teknologi Sistem Informasi Jurnal Komputasi Jurnal Teknoinfo Jurnal Tekno Kompak Journal of Electronics, Electromedical Engineering, and Medical Informatics Jurnal Pengabdian Kepada Masyarakat (JPKM) Tabikpun Journal of Applied Data Sciences Buguh: Jurnal Pengabdian Kepada Masyarakat International Journal of Electronics and Communications Systems Jurnal Pepadun Journal of Data Science and Software Engineering Warta LPM Laporan Upaya Nyata Inovasi Ilmu Komputer (LUNIK) Integra: Journal of Integrated Mathematics and Computer Science Jurnal Komputasi
Lumbanraja, Favorisen R
Jurusan Ilmu Komputer, Fakultas Matematika Dan Ilmu Pengetahuan Alam, Universitas Lampung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Social Sciences Other

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Journal : joiv international journal on informatics visualization

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A New Feature Extraction Approach in Classification for Improving the Accuracy of Proteins Damayanti, -; Lumbanraja, Favorisen Rosyking; Junaidi, Akmal; Sutyarso, -; Susanto, Gregorius Nugroho; Megawaty, Dyah Ayu
JOIV : International Journal on Informatics Visualization Vol 9, No 1 (2025)
Publisher : Society of Visual Informatics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62527/joiv.9.1.2589

Abstract

Proteins play a vital role in life as essential macromolecules, consisting of linear heteromeric biopolymers formed by amino acids covalently bonded through peptide bonds. They contribute to cell development and bolster the body's defense mechanisms. Post-translational modification processes, such as glycosylation, are necessary for proteins to function optimally. Glycosylation involves adding sugar groups to proteins, playing a critical role in various protein folding processes. Dysregulation of protein glycosylation can lead to diseases like Alzheimer's and cancer. Manual classification of glycosylated proteins is time-consuming, necessitating a faster approach. This study aims to expedite glycosylated protein classification using novel methods like AAindex, CTD, SABLE, hydrophobicity, and PseAAC for increased accuracy, comparing them with existing approaches. The dataset comprises protein sequences sourced from the openly accessible UniProt database. Results demonstrate that glycosylated protein prediction achieved 100% accuracy, surpassing previous approaches. Several features contributed to this improvement, with Hydrophobicity making a significant contribution at 24%, and PseAAC making the most significant contribution at 40% among the five extraction methods developed.
Co-Authors - Damayanti . Wamiliana Adawiyah, Laila Adinda Aulia Sari Admi Syarif Admi Syarif Admi Syarif Aflaha Asri Ahyarudin AKBAR RISMAWAN TANJUNG Akbar, Mohammed Raihan Akmal Junaidi Akmal Junaidi Akmal Junaidi Alfa Rizki Fadlillah Amelia Jasmine Andrian, Rico Annisa Rizqiana Apri Candra Ardiansyah Ardiansyah Aristoteles Aristoteles, Aristoteles Asmiati Asmiati Aulia Putri Ariqa Ayu Amalia Bambang Hermanto Damayanti Damayanti Danu Sasmita Desti Fatmalasari Destian ade anggi Sukma Dian Kurniasari Dian Kurniasari Didik Kurniawan Dwi Kartini, Dwi Dwi Sakethi Dwi Sakethi, Dwi Edi Arif Effendi Eliza Fitri Elly Lestari Rusitati Erdi Suroso Fanni Lufiana Fanni Lufiana Farida Ariyani Febi Eka Febriansyah Febi Eka Febriansyah Fitriyana, Silfia Hadi, Normi Abdul Hamim Sudarsono . Hamzah Hanif Hdiana, Yazid Zinedine Hendra Kurniawan Heningtyas, Yunda Hijriani, Astria Igit Sabda Ilman Ika Rahma Alia Indah Pasaribu Ira Hariati Br Sitepu Irawati, Anie Rose Irwan Adi Pribadi Jasmine, Amelia Jihan Aferiansyah Junaidi Junaidi Junaidi Junaidi Khairun Nisa Kristina Ademariana Kurnia Muludi Kurnia Muludi Kurnia Muludi Kurnia Muludi Lilies Handayani M. Iqbal Parabi M. Iqbal Parabi M. Juandhika Rizky Machudor Yusman Manurung, Yunita Rosalina Megawaty, Dyah Ayu Meria Nensi Muhammad Reza Faisal, Muhammad Reza Muhammad Reza Habibi Muhammad Rizki Muhaqiqin Muhaqiqin Muliadi Mustofa Usman Nadila Rizqi Muttaqina Naurah Nazhifah Nirwana Hendrastuty Nova Ayu Lestari Siahaan Nugroho Susanto, Gregorius Nuning Nurcahyani Nurdin, Muhaymi Nurhasanah Nurhasanah Nurjoko Nurjoko Parjito Parjito Prabowo, Rizky Pratama, Rinaldo Adi Priyambodo Priyambodo Priyambodo Priyambodo Putri, Gendis Ananda Qory Aprilarita Rahmat Safe'i Raka Akbar Hartolo Rangga Agustiantino Reza Aji Saputra Rico Andrian Ridho Sholehurrohman Ridho Sholehurrohman RM Sulaiman Sani Rosdiana, Siti Rudy Herteno Rudy Herteno Rusitati, Elly Lestari Saragih, Triando Hamonangan Shofiana, Dewi Asiah Sintiya Paramitha Siti Aisyah Solechah Siti Rosdiana Su'admaji, Arif Susanto, Gregorius Nugroho Sutyarso Sutyarso Sutyarso, - Syangap Diningrat Sitompul TANJUNG, AKBAR RISMAWAN Tiyara Saghira Tristiyanto Tristiyanto Tristiyanto Wamiliana Wamiliana Wamiliana Warsono Warsono Warsono Warsono Warsono Wartariyus Wartariyus YOHANA TRI UTAMI, YOHANA TRI Zaenal Abidin Zuliana Nurfadlilah