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Effectivity of Stichopus hermanii Supplementation to Prevent Oral Candidiasis on Rats Paramita Devi Oktaviani; Endah Wahjuningsih; Dwi Andriani
Denta Journal Kedokteran Gigi Vol 12 No 1 (2018): Februari
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Abstract

Background: Candida albicans is normal flora of oral cavity that can be pathogenic due to predisposition influence so that trigger Oral candidiasis. Stichopus hermanii suspected as an Oral candidiasis therapy because it contain antioxidant compound, antitumor and antifungi. Objective: Analyzing the effectiveness of Stichopus hermanii supplementation as a protective effect of oral candidiasis in Rats exposure to smoke. Materials and Methods: This experiment is post test only group control design using 35 male rats divided into 5 groups(X). X1 (negative control), X2 (positive control), X3 (Stichopus hermanii powder 0,0225mg/kgBB), X4 (Stichopus hermanii powder 0,045mg/kgBB), X5 (Stichopus hermanii powder 0,09mg/kgBB). Candida albicans induced into the mouth by an oral swab using cotton bud 3 times a week for 8 weeks. Smoke exposure as a predisposition factor be given 3 bars per day for 8 weeks. The rats being killed and tongue biopsies measure the thickness of tongue epithelium. The obtained data analyzation using One Way ANOVA and LSD test. Result: There is a significant difference (p<0.05) between X1 and X2, X1 and X3, X1 and X4, X1 and X5, X2 and X3, X2 and X4, X2 and X5, X3 and X5. Conclusion: Adduction of Stichopus hermanii capable of reducing risk of Oral candidiasis. Supplementation of Stichopus hermanii powder 0,09mg/kgBB is the most effective reduce thickness of the tongue epithelium in the group that exposure to smoke and induced of Candida albicans.
The Effect of Acanthus Ilicifilius Extract On Anticandida Albicans Antibody in Wistar Rats with Oral Candidiasis Immunosupressed Model Dwi Andriani; Dwi Setianingtyas; Nafi’ah
Denta Journal Kedokteran Gigi Vol 11 No 1 (2017): Februari
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Background: Candida albicans (C.Albicans) causes oral candidiasis. Candida adhesion proteins stimulate the immune system to eliminate C.albicans chloroform extract of acanthus leaves ilicifolius have inhibitory against C.Albicans. Purpose: To proved the potential Acanthus ilicifolius (A.ilicifolius) extract to inhibit the growth of C.Albicans in rats with oral candidiasis. Materials and Methods: This study was true experimental with post test only control group design. Wistar rats were used and imunosupressed with dexamethasone and ditetrasiklin peroral after that induced by C.albicans 6x108 on the tongue of rats for14 days. Divided into five groups, healthy (G1), candidiasis (G2), treatment group 1 (G3): candidiasis + nystatin, Treatment 2 (G4): candidiasis+extract A.Ilicifollius 8%, and Treatment 3 (G5) : candidiasis+extract A.Ilicifollius 16%. The rats was treated for 14 days after induction of candida. A.Ilicifollius chloroform extraction method was maceration. Samples was processed immunohistochemistry staining methods and added antibody anticandida albicans (IgG mouse). Observed the results using microscope (magnification 400x). Data were analyzed with the Kruskal-Wallis and Mann Whitney. Results: There was significant differences between G1 with G2, G3, G4, G5 (p˂0,05). There was significant difference between G2 to G3, G4 and G5 (p˂0,05). There was no significant difference between G3, G4, and G5 (p˃0,05). Conclusion. A.ilicifollius extract have potential to inhibit the growth of Candida albicans in rats with oral candidiasis.
Efektifitas Sabun Cair Ekstrak Kulit Nanas Sebagai Pembersih Basis Gigi Tiruan Resin Akrilik Heat Cured Terhadap Pertumbuhan Candida Albicans Tiffany Augusta Posuma; Meinar Nur Ashrin; Dwi Andriani
Denta Journal Kedokteran Gigi Vol 10 No 1 (2016): Februari
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Background: Candida albicans acts as a trigger to denture stomatitis. Prevention of denture stomatitis can be done by cleaning dentures with mechanic and chemical methods. Bromelin enzymes from pineapple can be use as a chemical substance to purify dentures for its ability to prevent the growth of Candida albicans with its proteolytic activity. Objectives: to determine the influence of soap from pineapple peel extract as acrylic resin heat cured denture cleanser in Candida albicans impure. Materials and Methods: The experiment is post test only group design. The subject is divided into 6 groups. Control group (aquadest), Positive control group (soap with lime extract brand X), and four treatment groups (soap from pineapple peel extract with 0%, 3,5%, 7%, and 14% concentration). Each group is brushed with an electric tooth brush for 5’. Then each sample is inserted into Saboraud Dextrose Broth and 0,1 ml is taken and is vortexed for 30’ then is incubated in Saboraud Dextrose Agar for 24 hours. The colony is counted with the colony counter in CFU/ml. The data will be tested with One Way ANOVA and continued with LSD test. Result: The mean of Candida albicans colony in K-, P1, P2, P3, P4, K+ is 44.00; 32.25; 2.25; 6.00; 11.50; 19.00. There is a difference between the control groups and all the treatment groups (p<0,05). Conclusions: Soap from pineapple peel extract with the concentration 3,5% is the most effective soap as an acrylic resin heat cured denture cleanser to influence the growth of Candida albicans
Perbedaan Efektivitas Ekstrak Daun Mangrove Acanthus ilicifolius Dengan Sodium Bikarbonat 5% Terhadap Penurunan Jumlah Koloni Candida albicans Pada Perendaman Nilon Termoplastik Aviyuda Prabowo; Paulus Budi Teguh; Dwi Andriani
Denta Journal Kedokteran Gigi Vol 9 No 2 (2015): Agustus
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

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Background: Nylon thermoplastic is denture base materials are often used. Dentures cleansing immersion can reduce calculus accumulation and Candida albicans (C.albicans) attachment. Sodium bicarbonate 5% is commonly used but has flaws. Acanthus ilicifolius leaves can be alternative herbal ingredients for denture cleanser because it has potency as antifungal and antibacterial. Purpose: To compare the difference in the effectiveness of antiC.albicans between Acanthus ilicifolius leaf extract and sodium bicarbonate 5% on nylon thermoplastic immersion. Materials and Methods: This study was true experimental laboratories with post test only control group design. The subjects in this study was a nylon thermoplastic soaked for 5 minutes and were divided into 5 groups: negative control group (DMSO 1%), positive control group (Sodium Bicarbonate 5%), and treatment groups (Acanthus ilicifolius leaf extract 1% , 0.5%, 0.25%). 0.1 ml of Sabouraud broth that has been contaminated with C.albicans in the immersion nylon thermoplastic then cultured in media SDA and incubated for 24 hours. Colony counted by colony counter in CFU/mL. The datawas processed by one way ANOVA and followed by LSD test. Result: There were differences in the number of colonies of C.albicans significantly between treatment groups with the negative control extract 1% and 0.5% (P <0,05) there is no significant difference between the negative control group with treatment group 3 (P3) (P>0,05). Conclusion: There were differences in the effectiveness of anti-C.albicans of Acanthus ilicifolius leaf extract concentration of 1% and 0,5% with sodium bicarbonate 5% on nylon thermoplasticimmersion
Analysis of P5 Activities in Forming Cultural Character at the Seventh Grade Students of SMP N 1 Buay Pemuka Peliung Nasyiatul Asiyah; Ainur Rohmah; Dwi Andriani
RISOMA : Jurnal Riset Sosial Humaniora dan Pendidikan Vol. 3 No. 2 (2025): Maret: RISOMA : Jurnal Riset Sosial Humaniora dan Pendidikan
Publisher : Asosiasi Ilmuwan Pendidikan, Sosial, dan Humaniora Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/risoma.v3i2.582

Abstract

This research aims to analyze the implementation of the Project for Strengthening the Pancasila Student Profile (P5) in shaping the cultural character of seventh-grade students at SMPN 1 Buay Pemuka Peliung. The primary focus of the research is to evaluate the forms of P5 activities, such as batik-making and folklore writing, and to identify the supporting and inhibiting factors in their implementation. The results show that the P5 activities have effectively helped students understand and appreciate local culture and enhanced teamwork skills through group activities. Overall, P5 has significantly contributed to make stronger cultural character among students, although challenges such as time constraints and limited resources were encountered.