Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan

PENGEMBANGAN SEDIAAN EMULGEL MENGANDUNG MINYAK BIJI ANGGUR (Vitis vinifera L.) DAN UJI AKTVITAS ANTILUKA TERHADAP TIKUS WISTAR JANTAN (Rattus norvegicus) Sani Ega Priani; Indah Ayu Lestari; Fetri Lestari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (190.718 KB) | DOI: 10.36387/jiis.v4i1.233

Abstract

Grape seed oil has wound healing activity since contains compounds such as flavonoids, polyphenols, saponins and linoleic acid. The purpose of this study is formulate emulgel containing grape seed oil with good physical characteristic and observed the wound healing activities of the oil and formulated emulgel. The research was begin with grape seed oil characterization and required HLB determination. The emulgel was made using combination Tween 80 and Span 80 as emulgator and carbomer as gelling agent with variation of oil concentration (10%, 20% and 30%). The formulation then subjected to physical evaluations including organoleptic, pH, spreadability, viscosity and rheology, sterility, and stability tests. Wound healing activity test of selected formula was done on seven groups of male Wistar rats. The emulgel containing grape seed oil with HLB value 8, has good physical, sterility, and stability characteristics. In vivo activity test showed that emulgel containing 20% and 30% grape seed oil have wound healing activity that statistically different compared with control (P<0.05) and the activity was not statistically different with marketed product (P>0.05).
UJI AKTIVITAS ANTIBAKTERI SEDIAAN MIKROEMULSI MINYAK JINTEN HITAM (Nigella sativa L.) TERHADAP TIGA BAKTERI PENYEBAB JERAWAT Sani Ega Priani; Tati Kurniati; Lanny Mulqie
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (306.387 KB) | DOI: 10.36387/jiis.v5i1.349

Abstract

Black seed oil is known to contain thymoquinone and other active compounds that have antibacterial activity and potential to be developed as an anti-acne agent. The objective of this research is to develop microemulsion gel containing black seed oil and determine the antibacterial activity to three acne-causing bacteria. Black seed oil was characterized and developed to microemulsion gel preparation. Microemulsion gel was prepared using tween 80, glycerine, HPMC as surfactant, cosurfactant, and gelling agent. Microemulsion gel was evaluated including organoleptic, pH, viscosity, rheology, and stability tests. Antibacterial activity was conducted by a well diffusion method to Propionibacterium acnes, Staphylococcus epidermidis, dan Staphylococcus aureus. The result shows the formulated microemulsion gives transparent appearance and stabile. The microemulsion gel has an antibacterial activity to Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus with an average inhibitory zone 15.00 ± 1.70, 12.7 ± 0.42, 14.39 ± 0.37 mm, respectively.
Co-Authors Ainul Fatihah Halim Aisyah Nurul Fitri Aisyah, Nurul Siti Almirah Azis Amila Gadri Anan Suparman Anan Suparman Anan Suparnan Anindi Febrilia Annisa Khansa Pratiwi Aprian Dwiatama Arini Gania Shapira Aulia Fikri Hidayat Clarisa Ananda Putri Putri Darijanto, Sasanti Tarini Debby Prihasti Ayustine Delfiana Aura Efrida Desti Puspa Rahayu Dina Mulyanti Dina Mulyanti Dina Mulyanti Dina Mulyanti Dinda Ayu Fauziyah Dinnanda Yussepina Wulansari Dinnanda Yussepina Wulansari Dona Indriastuti Dwiatama, Aprian Dyah Ayu Nurismawati Efrida, Delfiana Aura Eka Darma, Gita Cahya Faqih Radina Fetri Lestari Fetri Lestari Fida Surtiniyati Shofia Fitri Mellyna Cantika Fitrianti Darusman Frida Anggita Amalia G.C. Eka Darma Gita Cahya Eka Darma Gita Cahya Eka Darma Halim, Ainul Fatihah Hanifa Rahma Hanifa Rahma Hasna Syakira Fauziah Hilmi Fauzan Nurhakim Indah Ayu Lestari Indra T Maulana Indra Topik Maulana Iwo, Maria Immaculata Jahra Farhanuddin Lanny Mulqie Linda Nur'Aini Livia Syafnir Maria Immaculata Iwo Maria Immaculata Iwo Melati Sasabila Mentari Luthfika Dewi Mentari Luthfika Dewi Mira Nurseha Muhammad Taufik Septian Mulkiya, Kiki Nadya Lutfiah Nashita Rafawziya Nazela Constantia Hilyatul Aulia Neneng Alifia Nur Fauziah Nurrayyan Nurrayyan Nurrayyan, Nurrayyan Nurul Siti Aisyah Pedriantini Iqlima Subekti Putri, Clarisa Ananda Radina, Faqih Rafanisa Apriansah Rafika Susun Nursunda Raisha Az Zahra Ratih Aryani Ratih Aryani Ratih Aryani Ratih Aryani, Ratih Ratri Putri Chairunnisa Restianti Mutiara Reyhan G Reza A K Rizki Anggara Permana Rizza F. Nurasyfa Robby Prayitno Saadiya Noerman Salsabilla Wijaya Salwa Fajriati Maulida Mudakir Sasanti Tarini Darijanto Sasanti Tarini Darijanto, Sasanti Tarini Setianty, Tia Nur Shelma Azhari Abdilla Sifa Tamhaz Siti Anggina Ismiyati Solihat Soewondo, Budi Prabowo Somantri, Sri Yulianingsih Sri P. Fitraningsih Sri Peni Fitrianingsih Sri Yulianingsih Somantri Syafira Nissa Fahira Syafnir, Livia Syifa Siti Fatimah Azzahro Tati Kurniati Taufik Muhammad Fakih Tri Suciati Vina Azzahra Siti Nurhedian Widad Aghnia Shalannandia Wijaya, Salsabilla Wulan Kartika Dewi Yasmin Ramadania Burhanudin Zainab Zahira Azzahra Zalfa Ainun Rozak