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Karakterisistik Ekstrak Etanol 96% Kulit Jeruk Purut, Analisa GCMS dan Penetapan Nilai SPF (Sun Protection Factor) Dewi Rahma Fitri; Nespi Leo Renzi; Triana Triana; In Rahmi Fatria Fajar; Iin Hardiyati
JURNAL FARMASI DAN MAKANAN Vol 8 No 1 (2024): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v8i1.5534

Abstract

Exposure to high intensity ultraviolet light can cause sunburn, erythema, and tanning. In addition, ultraviolet radiation encourages the formation of ROS (reactive oxygen species) and nitrogen species (RNS), resulting in skin damage. To prevent this, antioxidants are needed which function to protect the skin from the bad effects of ultraviolet rays. Kaffir lime or what is commonly called kaffir lime has the potential to be a rich source of bioactive compounds. Kaffir lime peel contains essential oil components such as linalool, citronellol, geraniol, citronellal, and other components that have antioxidant activity. The aim of this research was to determine the characteristics of 96% ethanol extract of kaffir lime peel, chemical content and determine the SPF value. Kaffir lime peel was extracted using 96% ethanol and tested for extract characteristics, GCMS analysis and SPF value tested using the Mansur method. The results of the extract characteristics test showed a yield of 8.22%, air content of 8.74%, ash content of 2.17% and drying loss of 1.3%. Phytochemical screening showed results containing tannins, alkaloids and flavonoids and secondary metabolite compounds, GC-MS analysis showed the compounds beta-mycrene, gamma terpinene, linalool, terpinen-4-ol, geraniol, caryophyllene, nerolidol, sphatulenol, citronellal and Neral. SPF test results at a wavelength of 290-320nm with a concentration of 100 ppm: 23.096271, 150 ppm: 35.833618, 200 ppm: 45.047732, 250 ppm: 56.55952, 300 ppm: 68.919985
Analisis Fitokimia dan Analisis GCMS Ekstrak Kembang Bulan Tithonia Diversifolia (Hemsl.) A. Gray: Analisis Fitokimia Dan Analisis GC-MS Ekstrak Kembang Bulan Tithonia Diversifolia (Hemsl.) A. Gray Dewi Rahma Fitri; Dedri Syaefei; Kartika Sari
JURNAL FARMASI DAN MAKANAN Vol 8 No 2 (2025): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v8i2.6123

Abstract

Extracts from plants made from simple drugs are used as active ingredients, intermediates or finished product ingredients. The extract is standardized with two parameters specific and non-specific parameters. Non-specific extract quality parameters are indirect tests related to active compounds and their pharmacological activity, but aim to ensure the quality and uniformity of the extract. Specific extract quality parameters are aspects of chemical analysis that focus on the removal and quantification of active compounds in the extract that affect its pharmacological activity. The purpose of this study was to obtain a moonflower extract that meets specific quality standards related to the content of active compounds both qualitatively and quantitatively. The research method by testing the chemical compounds contained in the moonflower extract includes phytochemical screening, GCMS analysis and phenol content and total flavonoid content. The results of the study obtained 70% ethanol extract of moonflower with a yield value of 18.19%. Organoleptically, it is reddish brown in color, with a distinctive aroma of moonflower. The results of the water content are 9.79%, ash content 11.99%, and drying loss 13.64%. Contains flavonoids, phenols and tannins. The results of GCMS analysis contain compounds Benzenetricarboxylic acid, Cyclotetrasiloxane, octamethyl, Salicic acid, diethyl bis (trimethylsilyl) ester, Cyclotetrasiloxane-octamethyl, Heptasiloxane. Total flavonoid content is 3.2 Mg / g EQ and total phenolic content is Mg / g GEA.
AKTIVITAS FOTOPROTEKTIF IN VITRO SEDIAAN KRIM EKSTRAK HERBA PUTRI MALU (Mimosa pudica L.) SEBAGAI TABIR SURYA In Rahmi Fatria Fajar; Dewi Rahma Fitri; Yulis Adriana; Handawati Silitonga; Pra Panca Bayu Chandra
Jurnal Farmasi IKIFA Vol. 5 No. 2 (2026): JURNAL FARMASI IKIFA VOL. 5 NO. 2 JULI TAHUN 2026
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The sensitive plant (Mimosa pudica L.) has great potential as a raw material for cosmetics due to its bioactive compounds that can neutralize free radicals. One of its applications is as a sunscreen agent that protects the skin from the harmful effects of the sun’s ultraviolet (UV) radiation. This study aims to determine the Sun Protection Factor (SPF) value of a 70% ethanol extract of the sensitive plant, formulate it into a cream, and evaluate the physical characteristics and sunscreen activity of the formulation. The in vitro SPF value was calculated using UV-Vis spectrophotometry based on the Mansur formula. The cream formulations were prepared in four variations with different extract concentrations: F0 (0%), F1 (0.3%), F2 (0.6%), and F3 (0.9%). Physical evaluation of the formulations included organoleptic testing, homogeneity, spreadability, pH, and viscosity. The results of the physical evaluation showed that all four formulations exhibited good homogeneity. The spreadability test yielded results that met the requirements (5–7 cm), and the pH test results fell within the safe range for the skin (4.5–6.5). The viscosity of the creams decreased as the concentration of the added extract increased. The SPF test results for the cream formulations showed the following values: F0 at 1.8810 (no protection), F1 at 14.2306 (maximum protection category), F2 at 27.2598 (ultra protection category), and F3 at 33.1475 (ultra protection category). Conclusion: A 70% ethanol extract of the putri malu herb was successfully formulated into a sunscreen cream that meets physical quality requirements, and increasing the extract concentration significantly enhanced its photoprotective activity, reaching the ultra protection category.
Peningkatan Pengetahuan Melalui Edukasi Dagusibu pada Ibu Kader Tentang Dexametason di RW 02 Semanan, Kalideres, Jakarta Barat Mutawalli Sjahid Latief; Febri Hidayat; Eka Dipta; Dede Komarudin; Dewi Rahma Fitri; In Rahmi Fatria Fajar; Yulis Adriana; Jessica Rusli
INTEGRITAS : Jurnal Pengabdian Vol 10 No 1 (2026): JANUARI - JULI
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat - Universitas Abdurachman Saleh Situbondo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36841/integritas.v10i1.7341

Abstract

Pengelolaan obat yang tepat di rumah tangga sangat penting untuk menjamin keamanan dan efektivitas terapi. Namun, pengetahuan dan kesiapan ibu kader dalam mendapatkan, menggunakan, menyimpan, dan membuang obat secara benar masih rendah, sehingga penggunaan obat yang rasional menjadi terhambat. Pengabdian masyarakat ini bertujuan meningkatkan pengetahuan dan kesiapan ibu kader di RW 02 Kelurahan Semanan, Kalideres, Jakarta Barat melalui edukasi DAGUSIBU (Dapatkan, Gunakan, Simpan, dan Buang obat secara tepat) menggunakan presentasi dan leaflet, dengan fokus khusus pada penggunaan Dexametason. Penelitian ini menggunakan desain deskriptif pretest-posttest satu kelompok dengan 72 responden. Hasil pre-test menunjukkan kategori “baik” sebesar 38,9%, yang meningkat menjadi 76,4% pada post-test setelah edukasi. Uji Wilcoxon menunjukkan perbedaan yang signifikan secara statistik (p=0,000; p<0,05). Edukasi DAGUSIBU terbukti efektif meningkatkan pemahaman ibu kader tentang Dexametason dan pengelolaan obat secara umum, sehingga diharapkan mendorong penggunaan obat yang lebih aman, tepat, dan ramah lingkungan di masyarakat.
FORMULASI SEDIAAN SABUN MANDI CAIR EKSTRAK ETANOL BUAH NANGKA (Artocarpus heterophyllus Lam.) Dewi Rahma Fitri; Hanifah Mustikawati; Divia Tita Afianty
IONTech Journal Vol. 1 No. 1 (2020): Agustus 2020
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v1i1.25

Abstract

Abstrak Sabun merupakan kosmetik paling dibutuhkan manusia. Sabun digunakan untuk membersihkan tubuh dari kotoran dan bakteri. Ekstrak buah nangka mengandung senyawa polifenol dan tanin, dimana senyawasenyawa tersebut berkhasiat sebagai antibakteri. Ekstrak buah nangka mengandung vitamin C yang baik untuk kesehatan kulit dan kelembaban alami kulit. Penelitian ini bertujuan untuk membuat formulasi sabun mandi cair ekstrak etanol buah nangka yang memenuhi pesyaratan uji sesuai dengan SNI . formulasi dibuat dengan tiga varian kadar ekstrak yaitu pada kosentrasi F1 2,5 %, F2 5 %, dan F3 7,5 %. Ekstrak etanol buah nangka diperoleh melalui proses maserasi selama 5 hari dengan menggunakan pelarut etanol 70 %, Evaluasi sediaan sabun mandi cair ekstrak buah nangka yaitu organoleptik, homogenitas, pH, bobot jenis, viskositas, stabilitas busa. Pengujian disesuaikan dengan aturan Standar Nasional Indonesia (SNI). Hasil penelitian menunjukkan pada F1 dan F2 dengan konsentrasi 2,5 % dan 5 % telah memenuhi syarat Standar Nasional Indonesia (SNI) dengan nilai pH 7,70 dan 6,51, Bobot jenis yang dihasilkan adalah 1,0714, 1,0738, 1,0909 g/mL, telah memenuhi syarat SNI yaitu 1,01 - 1,10 g/mL. Abstract Soap is the most needed cosmetic for humans to cleanse the body of impurities and bacteria. Jackfruit extract contains polyphenol compounds and tannins, these compounds are efficacious as an antibacterial. Jackfruit extract contains vitamin C for skin health and natural moisture. This study aims to make a liquid bath soap formulation of jackfruit ethanol extract that meets the test requirements in accordance with SNI. The formulation was made with three variants of extract levels namely at F1 concentration 2.5%, F2 5%, and F3 7.5%. Jackfruit ethanol extract obtained through maceration process for 5 days using 70% ethanol solvent, Evaluation of jackfruit juice liquidbath soap preparations namely organoleptic, homogeneity, pH, specific gravity, viscosity, foam stability. Testing is adjusted to the rules of the Indonesian National Standard (SNI). The results showed that F1 and F2 with concentrations of 2.5% and 5% had met the requirements of the Indonesian National Standard (SNI) with pH values of 7.70 and 6.51, the resulting species weight was 1.0714, 1.0738, 1 , 0909 g / mL, has fulfilled SNI requirements, namely 1.01 - 1.10 g / mL.
COMPARISON OF PHYSICAL PROPERTIES PALM WAX AND PARAFFIN WAX AND REPELLENCY EFFECT OF AROMATHERAPY KAFFIR LIME PEEL OIL: erbandingan Basis Lilin Palm Wax Dan Paraffin Wax Terhadap Sifat Fisik Dan Daya Tolak Nyamuk Lilin Aromaterapi Minyak Kulit Jeruk Purut Sebagai Reppelent Dewi Rahma Fitri
IONTech Journal Vol. 4 No. 2 (2023): Agustus 2023
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v4i2.92

Abstract

Latar Belakang: Pemilihan basis lilin yang tepat akan mempengaruhi sifat fisik lilin aromaterapi dalam performanya. Palm wax mempunyai sifat mudah larut dalam air dan tingkat allergen kecil. Tujuan penelitian ini untuk memperoleh lilin aromaterapi bersifat repellent yang mempunyai sifat fisik lilin yang baik dan mempunyai kemampuan daya tolak terhadap nyamuk Aedes aegypt. Metode: Kulit jeruk purut disetilasi diperoleh 93 ml dengan bobot jenis 0,9. Formula basis lilin perbadingan bahan dasar lilin palm wax dan asam sterat yaitu A1(10:90), A2(90:10), A3(50:50), A4(70:30), A5(30:70), paraffin wax dan asam stearat B1(75:25), B2(50:50) dan B3(90:10). Hasil: uji sifat fisik lilin semua sediaan mempunyai warna putih, tidak cacat, dan tidak ada gelembung udara, lama waktu bakar A1:10jam 5menit, A2:6jam 47menit, A3:8jam 20menit, A4:7jam 15menit, A5:9jam 7menit, B1:6jam 40menit, B2:7jam 26menit, B3:9 jam 5menit dan titik leleh A1:53.3°C , A2:55.8°C , A3:56.8°C, A4:54.9°C,A5:57.5°C, B1:54,4° C, B2:56,6° C, B3:58,8° C. Basis lilin yang digunakan adalah basis A3(50:50) dan B2(50:50) merupakan basis dengan perbandingan komposisi seimbang. Hasil uji sifat fisik lilin aromaterapi A31(50:50) dan B21(50:50) berwarna kuning, tidak cacat, tidak ada gelembung, waktu bakar A31:7jam 3 menit, B21:6jam 43 menit, titik leleh A31:54,8°C, B21:54,9, dan daya proteksi terhadap nyamuk aedes aegepty A31:86,6%, B21:83,3%. Kesimpulan: Diperoleh lilin aromaterapi palm wax sebagai basis lilin memenuhi sifat fisik sediaan lilin yang baik yaitu tidak cacat, tidak ada gelembung udara, waktu bakar 7jam 3menit, dan daya proteksi terhadap nyamuk aedes aegepty sebesar 86,6%.
Counseling and demonstration of the use of medicinal plants in the South Bambu sub-district, West Jakarta: Penyuluhan dan demo pemanfaatan tanaman obat di wilayah kelurahan bambu selatan Jakarta barat Yulis Adriana; Febri Hidayat; Dede Komarudin; Dewi Rahma Fitri
Journal of Community Development and Empowerment Vol. 2 No. 1 (2026): Journal of Community Development and Empowerment, January 2026
Publisher : Lembaga Publikasi Ilmiah Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70716/jocdem.v2i1.373

Abstract

The community service program that has been implemented by the Pharmacy study program of the Al Kamal Institute of Science and Technology regarding counseling and demonstrations on the use of medicinal plants to improve public health in the South Bambu sub-district, West Jakarta. Counseling and demonstrations on the use of medicinal plants are educational activities to introduce, teach how to process, and demonstrate the use of medicinal plants for health. This activity includes providing material on the benefits of medicinal plants, how to process them such as boiling or mixing, as well as direct demonstrations on making simple potions and cultivation. The purpose of this activity is to increase the knowledge and skills of the community so that they can utilize medicinal plants as an alternative natural treatment to maintain daily health. This counseling and demonstration was carried out at the Bambu Kuning Child-Friendly Integrated Public Space (RPTRA). The Bambu Kuning Child-Friendly Integrated Public Space (RPTRA) is one of the places in the South Bambu City Village, Palmerah District, West Jakarta. The facilities in the RPTRA are not only child-friendly, but also disabled-friendly. In addition, there are many types of TOGA plants planted by the administrators in the Bambu Kuning RPTRA area. Counseling activities on the use of medicinal plants and demonstrations on making juice mixed with single garlic, lemon juice, ginger juice, apple cider vinegar and honey as well as making healthy drinks from aloe vera plants. This activity received a very good response from the local community with many questions about the use of medicinal plants to support public health
Formulasi Gel Luka Bakar Nanopartikel Ekstrak Daun Kipait (Tithonia diversifolia (Hemls.) A. Gray) Dewi Rahma Fitri; In Rahmi Fatria Fajar; Dedri Syafei
JURNAL KESEHATAN PERINTIS Vol. 12 No. 2 (2025): Jurnal Kesehatan Perintis
Publisher : LPPM UNIVERSITAS PERINTIS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33653/z5m74532

Abstract

Penyembuhan luka bakar dapat berlangsung optimal apabila senyawa aktif mampu berpenetrasi dengan baik ke dalam mukosa. Salah satu faktor yang memengaruhi penetrasi adalah ukuran partikel obat. Penerapan teknologi nano di bidang farmasi memiliki berbagai keunggulan, seperti meningkatkan kelarutan senyawa, meningkatkan absorpsi, serta memungkinkan penggunaan dosis yang lebih rendah. Penelitian ini bertujuan untuk memperoleh nanoekstrak daun kipait (Tithonia diversifolia (Hemls) A. Gray) dan memformulasikannya ke dalam sediaan gel sebagai agen anti luka bakar. Penelitian ini menggunakan metode eksperimental. Ekstraksi daun kipait dilakukan dengan metode maserasi menggunakan etanol 70%. Ekstrak kental diuji parameter spesifik meliputi uji organoleptik, identifikasi senyawa metabolit sekunder, penetapan kadar fenol total, serta analisis GC-MS. Parameter nonspesifik yang diuji meliputi kadar air, kadar abu, dan susut pengeringan. Pembuatan nanopartikel dilakukan dengan metode gelasi ionik menggunakan kitosan dan NaTPP. Nanoekstrak diformulasikan dengan variasi perbandingan kitosan 0,3% dan NaTPP 0,1% pada tiga formula (F1, F2, dan F3). Karakteristik nanoekstrak meliputi ukuran partikel, zeta potensial, indeks polidispersitas (PDI), dan morfologi menggunakan SEM. Selanjutnya, nanoekstrak diformulasikan dalam sediaan gel. Hasil penelitian menunjukkan bahwa ekstrak daun kipait mengandung flavonoid, fenol, saponin, alkaloid, serta steroid/terpenoid dengan kadar fenol total 69,6 mg/g GAE. Formula terbaik (F3) menghasilkan ukuran partikel 300 nm, zeta potensial 35,0, PDI 0,489, dan morfologi bulat beraturan. Sediaan gel nanoekstrak pada konsentrasi 0,69% dan 1,38% memenuhi persyaratan mutu fisik gel. Disimpulkan bahwa sediaan gel nanoekstrak daun kipait memiliki kualitas yang baik sebagai sediaan anti luka bakar.