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All Journal Medicina journal of internal medicine E-Jurnal Medika Udayana E-Jurnal Udayana Medica Berkala Kedokteran The Indonesian Biomedical Journal Jurnal Penyakit Dalam Udayana ISM (Intisari Sains Medis) : Jurnal Kedokteran Bioscientia Medicina : Journal of Biomedicine and Translational Research Medical and Health Science Journal Neurologico Spinale Medico Chirurgico Bioscientia Medicina : Journal of Biomedicine and Translational Research GANESHA MEDICINA MEDICINUS Jurnal Indonesia Sosial Sains Journal of Global Pharma Technology Asian Journal of Social and Humanities Jurnal Ekonomi Kesehatan Indonesia Indonesian Journal of Endocrinology Metabolism and Diabetes (InaJEMD)
MADE RATNA SARASWATI .
Bagian Ilmu Penyakit Dalam RSUP Sanglah, Fakultas Kedokteran Universitas Udayana
Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences

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Journal : Medicina

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Seorangwanitadengan penyakit trofoblas gestasionaldankrisis tiroid Mayura, I Gusti Ngurah; Saraswati, Made Ratna
Medicina Vol 47 No 3 (2016): September 2016
Publisher : Medicina

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Abstract

Penyakit trofoblas gestasional (PTG) merupakan sebuah kondisi yang terkait dengan adanya jaringan trofoblastikplasenta setelah fertilisasi normal atau abnormal yangspektrumnya dari mola hidatidosa sampai keganasan. Krisistiroid mencerminkan status ekstrim dari spektrum tirotoksikosis. Terjadinya PTG denganhipertiroid dapat menjadikrisis tiroid pasca-operasi atau kuretase. Subunit ? padahuman chorionic gonadotropin(hCG), mirip dengan subunit?luteinising hormone(LH) dandapat mengaktifkan reseptortyrotropin stimulating hormone(TSH)ketika diproduksidalam jumlahberlebihan dan menginduksi tirotoksikosis. Kasus adalah seorang wanita berusia 24 tahun datangdengan keluhan badan lemas, sesak napas, demam, dan batuk, denganriwayat mola hidatidosa. Pada pemeriksaan fisisdidapatkan takikardi, pireksia, dispne, ronki, dan massa abdominal. Dari toraks foto didapatkan gambaran metastasisparu dan infeksi paru, pada pemeriksaan penunjang didapatkan peningkatan penanda tumor, hipertiroid, danpeningkatan skor untuk krisis tiroid. Berdasarkan anamnesis, pemeriksaan fisis, dan pemeriksaan penunjangmendukung diagnosis PTG dengan metastasis paru, infeksi paru, dan krisis tiroid.[MEDICINA.2016;47(3):47-51].Gestasional trophoblastic disease (GTD) is a condition associated with the trophoblastic tissue of the placentaafter normal or abnormal fertilization, which the spectrum from hydatidiform mole to malignancy. Thyroid stormreflects the extreme state of thyrotoxicosis spectrum. The GTD with hyperthyroidism can be a thyroid storm postsurgeryorcurettage.The?subunitofhumanchorionicgonadotropin(hCG),similartothe?subunitofluteinisinghormone(LH) and can activate the receptor of tyrotropin stimulating hormone(TSH) receptor when producedexcessively and induced thyrotoxicosis. The case was a 24 year old women came with complaints of weakness,shortness of breath, fever, and cough, with a history of hydatidiform mole. On physical examination foundtachycardia, pyrexia, dyspnea, crackles, and abdominal mass. Obstained from thorax photo ilustration lung metastasisand pulmonary infection, from laboratorium found increase in tumor marker, hyperthyroidism, and increase score forthyroid storm. Base on history, physical examination, and laboratorium support the diagnosis of PTG with lungmetastasis, pulmonary infection, and thyroid storm. [MEDICINA.2016;47(3):47-51].
Co-Authors A.A Sagung Ika Nuriska A.A.Gde Budhiarta Agus Santosa Ake, Anselmus Anak Agung Gde Budhiarta Anak Agung Gde Budhiarta Anak Agung Gede Ari Nanda Bhaswara Anak Agung Gede Budhiarta Anak Agung Gede Mahaindra Putra Andika Budiartha, Putu Gede Azizah, Norma Nur Azizah Bondan Winarno Budhiarta, Anak Agung Gde Budi Ratna Aryani David Dharmawan Harjanto Devinta, Made Ratih Santi Dewa Ayu Sri Agung Suandewi Dewi, Putu Feby Miswari Dumilah Ayuningtyas Eti Kurniaty Gautama M, Putu Gizha Satrya Gede Agung Widya Iswara Gede Andrewartha Gozali, Theodorus Onesiforus Herawati Sudoyo I Gde Raka Widiana I Gde Suranaya Pandit I Gusti Ayu Sri Mahendra Dewi I Gusti Ngurah Kade Mahardika I Gusti Putu Suka Aryana I Ketut Suastika I Ketut Sustika I Made Ady Wirawan I Made Bagiada I Made Pande Dwipayana I Made Siswadi Semadi I Made Siswadi Semadi I Made Siswadi Semadi I Made Yoga Prabawa I Wayan Eka Satriawibawa I Wayan Hartadi Noor I Wayan Losen Adnyana I Wayan Putu Sutirta Yasa I Wayan Sudhana I Wayan Sumardika I. K. Suastika Ida Bagus Aditya Nugraha Ida Bagus Yorky Brahmantya Isabella Soerjanto Putri K Suastika Kadek Dina Puspitasari Kartadinata, Sarah Levina Katrin Wilentina Siahaan Ketut Suega Komang Agus Wira Nugraha Laksmi, Putu Pradnyasanti Made Ayu Devi Pita Loka Made Yogi Krisnanda Malik, Safarina G. Marisye Christantia Mayura, I Gusti Ngurah Mochtar, Fransiska Muhammad Aris Sugiharso Ni Ketut Rai Purnami Ni Luh Made Novi Ratnasari Ni Luh Putri Kresnasari Ni Made Sintia Anggia Sari Nym Astika Nyoman Arya Shridewi Abhigamika Oktavianthi, Suksma Pande Ayu Naya Kasih Permatananda Parastan, Rovie Hikari Prichilia Sarah Permadi R. Prawira Bayu Putra Dewa Ratih Pradnyandari Pemayun Rena, Ni Made Renny Anggreni Rheza Priyadi Rooseno, Ratna Rayeni Natasha Rusditha, Sarah - S., Hantono Safarina G. Malik Saraswati, Putu Ayu Indah Savitri, Putu Dian Hermawati Sari Sukma Oktavianthi Surya Sanjaya Funistera Susy Purnawati Tuty Kuswardani Wan Muhamad Syafiq Wardana, Rr. Cattleya Allayka Wimpie I Pangkahila Wira Gotera ¬Ni Putu Ade Tiwi Tyastarini Tyastarini