Article Per Year (5 Year)
p-Index From 2021 - 2026
1.513
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) Jurnal Kedokteran Brawijaya Majalah Kedokteran Bandung Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Jurnal Kesehatan Melayu Jurnal Gizi Klinik Indonesia Jurnal Respirologi Indonesia Majalah Kedokteran Andalas Narra J Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara
Dani Rosdiana
Department Of Internal Medicine, Faculty Of Medicine University Of Riau/Arifin Achmad General Hospital, Pekanbaru, Riau
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 28 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Narra J

 1 
Efficacy of pretomanid-containing regiments for drug-resistant tuberculosis: A systematic review and meta-analysis of clinical trials Simanjuntak, Arya M.; Daenansya, Raehan; Afladhanti, Putri M.; Yovi, Indra; Suyanto, Suyanto; Anggraini, Dewi; Rosdiana, Dani
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.402

Abstract

Concerns regarding the rise of drug-resistant tuberculosis (DR-TB) infections and the need for new drugs with shorter treatment time and fewer side effects have been voiced by the World Health Organization (WHO). The WHO revised its guideline to treat multi-drug resistant tuberculosis (MDR-TB) with a 6-month course of BPaLM (bedaquiline, pretomanid, linezolid and moxifloxacin) in 2022. However, a thorough study and meta-analysis of available evidence is required due to the limited confidence of the evidence confirming the effectiveness of pretomanid-containing regiments. The aim of this systematic review and meta-analysis was to evaluate the effectiveness of pretomanid-containing regiments in treating DR-TB patients. Data from six search engines were searched using inclusion criteria based on the PICOS framework. The keywords of pretomanid and tuberculosis or their alternatives were used. Using RoB2 Cochrane risk-of-bias tool for randomized clinical trials, data were independently extracted and the quality of the data was evaluated. Odds ratio (OR) and heterogeneity tests were used and the findings were presented in ORs and forest plots. A total of four studies with 237 patients was included in the final analysis and 204 (86%) patients had favorable outcome (cured) and 33 (14%) was not cured. Pretomanid-containing regimen (OR: 46.73; 95%CI: 11.76–185.7) and BPaLM/BPaL (OR: 41.67; 95%CI: 8.86–196.73) regimens were associated with favorable outcome (cured). This meta-analysis indicates that the pretomanid-containing regimen and the BPaLM/BPaL regimen could increase the chance to have favorable outcome in DR-TB patients.
Mortality and associated factors among community-acquired pneumonia patients: A cross-sectional study in a provincial referral hospital in Indonesia Rosdiana, Dani; Siregar, Fajri M.; Ediwi, Nabila C.; Putri, Rahmi T.; Nurrahma, Zuyyina ER.; Elisabet, Adinda; Sarassari, Rosantia; Safari, Dodi; Ilmiawati, Cimi; Elliyanti, Aisyah
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i2.1649

Abstract

Community-acquired pneumonia (CAP) poses a significant impact on the healthcare system due to rehospitalization and mortality. About one-third of hospitalized CAP patients died within one year. In addition to advanced age, vulnerable groups with comorbidities such as cancer, diabetes, and cerebrovascular disease (CVD) are more likely to suffer from severe CAP. The aim of this study was to investigate the factors linked to mortality in adult hospitalized CAP patients. The study extracted the medical records of patients aged ≥18 years, admitted to a referral hospital in Riau Province, who were diagnosed with CAP between January and December 2023. Multiple logistic regression step-wise analysis was employed to determine the factors associated with mortality in CAP patients. The study involved 334 patients with a median age of 58 years. Based on the confusion, urea, respiratory rate, blood pressure, and age ≥65 years (CURB-65) score, 11.9% of patients had severe CAP (CURB-65 scores 3 and 4). Age was a significant predictor of severe CAP (p≤0.001). The most prevalent comorbidities were malignancy (33.2%), CVD (30.2%), and diabetes (28.4%). Mortality incidence during hospitalization reached 35.9%. Significant factors associated with mortality in hospitalized CAP patients included renal dysfunction/elevated serum urea levels (p=0.031), CURB-65 score (p=0.023), vasopressor use (p≤0.001), mechanical ventilator use (p≤0.01) and steroid use (p=0.029). However, CVD was associated with a decreased risk of mortality (p=0.019). Gram-negative bacteria predominated, accounting for 50.6% of all positive isolates.  Several significant factors were associated with mortality in adult patients hospitalized with CAP at referral Hospital in Riau, including renal dysfunction, CURB-65 score, vasopressor use, mechanical ventilator use, and steroid use. This finding underscored the importance of early identification factors in CAP patients.
Co-Authors Abd. Rasyid Syamsuri Afladhanti, Putri M. Agung Ramadhan Agustiawan Aisyah Elliyanti Anwar Bet Ardini, Nadiah Yamanza Arfianti Arfianti Armi, Wahyuli Bet, Anwar Carlo Manuel Perangin-angin Cimi Ilmiawati, Cimi Daenansya, Raehan Darmawi Darmawi Dedi Afandi Dewi Anggraini Deyana, Frilly Dina Br Nababan Ediwi, Nabila C. Effendi, Dasril Eka Bebasari Elisabet, Adinda Elsa Sundari Erwin Christianto Esha, Indi Faradini " Fifia Chandra Harahap, Sari Hendra Asputra Hetty Hirfawaty Huriatul Masdar Huriatul Masdar Indra Fakhreza INDRA YOVI Kasih, Rani Rindang Kesumah, Dewi Iramayana Sandra Ligat Pribadi Sembiring Ligat Pribadi Sembiring M Firdaus J Karimi Mardhatilah, Ashifa Marlina Tasril Muhammad Arif Mukhyarjon Nisa Faradisa Hernita Nurrahma, Zuyyina ER. Olivia Makmur Pragita Ayu Saputri Prayogo Prayogo Puji Artanti Putri, Nabila Putri, Rahmi T. Rahmat Azhari Kemal Raja Merlinda Veronica Riezky Valentina Astari Safari, Dodi Safitri, Nuridha Audinia Saputri, Pragita Ayu Sarassari, Rosantia Simanjuntak, Arya M. Siregar, Fajri M. Suryani ", Suryani Suyanto Suyanto Tami Endriani Pardede Triani, Zhana Daisya Utami, Yurika Utami1 Marthalia Veronica, R. Merlinda Viona Ayu Safitri Yanti Ernalia yurika marthalia utami