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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Kimia Riset Jurnal Ilmiah Kedokteran Wijaya Kusuma THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Jurnal Ilmiah Soulmath : Jurnal Edukasi Pendidikan Matematika Jurnal Mandala Pharmacon Indonesia Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Medical Technology and Public Health Journal Sains dan Matematika Medicra (Journal of Medical Laboratory Science/Technology) Jurnal Abdimas Berdaya : Jurnal Pembelajaran, Pemberdayaan dan Pengabdian Masyarakat Jurnal Abdimas Kartika Wijayakusuma Indonesian Journal of Innovation Studies Procedia of Social Sciences and Humanities Prosiding SEMNAS INOTEK (Seminar Nasional Inovasi Teknologi) Jurnal Laboratorium Khatulistiwa International Journal Multidisciplinary Oshada Jurnal Teknologi Laboratorium Medik Borneo Jurnal Sains, Teknologi dan Kesehatan Manajemen Pelayanan Kesehatan Indonesian Journal Health Science and Medicine Jurnal Analis Kesehatan Kendari Academia Open
Chylen Setiyo Rini
Prodi Teknologi Laboratorium Medis, Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Sidoarjo
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Antibacterial Activity of Rhizome Extracts of Zingiber zerumbet (L.) Roscoeex Sm. Against Streptococcus pneumoniae: Aktivitas Antibakteri Ekstrak Rimpang Lempuyang Gajah (Zingiber zerumbet (L.) Roscoeex Sm.) Terhadap Bakteri Streptococcus pneumoniae Rohmah, Jamilatur; Rini, Chylen Setiyo
Procedia of Social Sciences and Humanities Vol. 3 (2022): Proceedings of the 1st SENARA 2022
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/pssh.v3i.361

Abstract

Research on the antibacterial activity of the ethanolic extract of lempuyang (Zingiber zerumbet (L.) Roscoe ex Sm.) against Streptococcus pneumoniae has been carried out using the disc diffusion method. Streptococcus pneumoniae is a bacterium that can cause respiratory tract infections (ARI), in its handling, people use antibiotics. Antibiotics themselves if used continuously lead to resistance. Currently, there are many studies regarding traditional medicines as antibacterials. The purpose of this study was to determine the secondary metabolite content of lempuyang elephant rhizome and to determine the antibacterial activity of lempuyang extract on Streptococcus pneumoniae bacteria. The method used in this research is the diffusion method with paper discs to determine the inhibitory power. The lempuyang plants used were obtained from the village of Tegal Bulu Banyuwangi and isolates of S. pneumoniae were obtained from the Central Health Laboratory (BBLK) Surabaya. The concentrations of the extracts used were 20, 40, 60, 80, and 100% with a positive control of chloramphenicol. The results showed that the ethanol extract of lempuyang (Zingiber zerumbet (L.) Roscoe ex Sm.) could inhibit the growth of S. pneumoniae bacteria, which was known from the inhibition zone formed. The inhibition test showed that the higher the concentration of lempuyang extract, the larger the diameter of the inhibitor formed. In lempuyang, the highest inhibition diameter was found at a concentration of 100% at 43.9 ± 3.6 mm. The results of phytochemical testing showed that the ethanol extract of lempuyang (Zingiber zerumbet(L.) Roscoe ex Sm.) contained alkaloids, flavonoids, saponins, steroids, triterpenoids, phenolics, and tannins.
Pelatihan Pengolahan Makanan Berbahan Dasar Daun Kelor Guna Mencegah Stunting Pada Anak Rini, Chylen Setiyo; puspitasari, puspitasari; Akbar, Aulia Rizky Fadhillah; Ambarani, Putri Yuli; Mufidah, Lailatul; al-akbar, Wildan; Yeninastiti, Reny
Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Vol 6, No 4 (2023): Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstormin
Publisher : Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/japhb.v6i4.5067

Abstract

Tingginya angka prevalensi stunting di Indonesia dan setiap tahun meningkat. Oleh sebab itu perlu solusi untuk membantu mengurangi angka perkembangan stunting di Indonesia. Salah satunya dengan perbaikan nutrisi bagi bayi atau balita. Pemanfaatan bahan alami seperti sayur atau buah yang ada disekitar bisa dilakukan untuk memenuhi kebutuhan nutrisi bayi dan balita. Daun kelor memiliki nilai tinggi yang dapat dijadikan sebagai bahan dasar makanan tambahan seperti camilan bagi bayi atau balita. Tujuan kegiatan pengabdian masyarakat adalah meningkatkan pemahaman dan pengetahuan dengan memberikan penyuluhan, pelatihan dalam mengolah makanan bergizi berbahan dasar daun kelor dengan inovasi terbaru untuk pertumbuhan balita dan anak-anak sehingga dapat mencegah stunting. Metode yang dilakukan antara lain sosialisasi materi, praktek pembuatan makanan, memberikan leaflet kepada peserta. Sasaran dalam kegiatan pengabdian masyarakat yaitu ibu-ibu di Desa Berbek Kecematan Waru, Sidoarjo. Tempat pengabdian masyarakat di kediaman ibu Dra. Hj. Zainab. Hasil dari kegiatan pengabdian masyarakat dengan sosialisasi terkait stunting dan pencegahannya terbukti efektif untuk meningkatkan pemahaman ibu-ibu di Desa berbek kecamatan waru Sidoarjo. Kegiatan inti dari penyuluhan ini adalah edukasi terkait stunting dan pencegahannya melalui daun kelor. Rekomendasi dari kegiatan pengabdian masyaraat ini dengan pemahaman ibu-ibu yang sudah semakin baik diharapkan dapat diapilikasikan pada kehidupan, sehingga dapat membantu penurunan kasus stunting khususnya di wilayah Desa Berbek Kecamatan Waru Sidoarjo. Kemudian pembentukan sumber daya manusia yang berkualitas, memiliki fisik dan intelektual yang tinggi juga diharapkan penurunan kasus stunting.
The Effect of Sembukan Leaf Extract (Paederia Foetida) on the Growth of Klebsiella Pneumoniae Bacteria with the Disc Method and the Contact Method setiyo rini, chylen; Pratiwi, Nova Linda
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 6 No 2 (2022): Medical Technology and Public Health Journal September 2022
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v6i2.3397

Abstract

Sembukan leaf (Paederia foetida) is a wild plant which is known to have many benefits and can be used as a medicinal plant. These plants contain bioactive compounds that function as antibacterial. This study aims to determine the ability of sembukan leaf extract to inhibit the growth of Klebsiella pneumoniae. The methods used in this study were disc diffusion and contact methods, with variations in the concentration of curd leaf extract 0%, 25%, 50%, 75% and 100%. The research data obtained were analyzed by One Way ANOVA with 95% confidence level (p<0.05). The best concentration with the disc diffusion method at a concentration of 75% with an inhibitory diameter of 15.25 mm with a strong category and the best percentage of inhibition method on sembukan leaf extract at 69.42% with a bacteristatic category at a concentration of 75%, while the results of the One Way ANOVA test that has been done obtained a significant value of p=0.000 (p<0.05) indicates a significant effect on the administration of sembukan leaf extract against Klebsiella pneumoniae bacteria. The results showed that sembukan leaf extract was able to inhibit the growth of Klebsiella pneumoniae.
Specific Primer Design of Leucine Rich Repeats and Guanylate Kinase Domain Containing (LRGUK) Genes in Type II Diabetes Mellitus Patients Mushlih, Miftahul; Tis’iyyah , Siti Nur Maghfiroh; Rini, Chylen Setiyo; Sari, Azizah Krismonita
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 6 No 2 (2022): Medical Technology and Public Health Journal September 2022
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v6i2.3476

Abstract

Diabetes Mellitus type II (DT2) is a disorder of insulin function (insulin resistance) caused by 2 factors, i.e. environmental and genetic factors. Previous studies have identified the presence of specific alleles that differentiate between DT2 and non-DT2 sufferers. Identification of the allele indicated leucine rich repeats and guanylate kinase domain containing (LRGUK) gene. The aim of this research was to design a specific primer to amplify LRGUK gene. The primer design was based on a 576 bp nucleotide base and added 100 bp in the 5'  and 100 bp in the 3' direction using NCBI-Primer BLAST. The primers produced were selected based on eight criteria’s. The results were validated with 6 samples of DT2 patients and visualized using agarose gel. The results of the analysis showed that the primers Forward 5'-TCCTACTCTGTGTCCTTCCTTG-3' and Reverse 5'-GTGGTGACAAGGAGG TTTGC-3' were able to amplify specifically with a length of 687 bp.
Antimicrobic On KAFFIR LIME (Citrus hystrix) leaves against Bacillus cereus : KILL TEST METHOD setiyo rini, chylen
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 7 No 1 (2023): Medical Technology and Public Health Journal March 2023
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v7i1.3837

Abstract

Kaffir lime (Citrus hystrix) is a horticultural plant that is widely used as a natural flavor in various food and beverage products. The content in lime leaves is useful for health, including flavonoids, minerals, vitamin C, limonoids, and carotenoids. Bacillus cereus causes a diarrheal disease that attacks the intestines. This study aims to determine the kaffir lime leaf extract in inhibiting the growth of Bacillus cereus bacteria using the Time-Kill Test method. This study used the Minimum Inhibitory Concentration (MIC) and Time-Kill Test methods. The MIC results in kaffir lime leaf extract that can inhibit bacteria at 2 mg/mL, while the Time-Kill Test shows a death phase at 24 hours. Kaffir lime leaf extract has a bacteriostatic effect at 0, 4, 8, and 24 hours, while amoxicillin and the combination of amoxicillin and extract have a bacteriostatic effect at 4, 8, and 24 hours. Based on the results of the One Way ANOVA test with a 95% confidence level (p <0,05) showed a significant effect of kaffir lime leaf extract on the growth of Bacillus cereus.
Analisis Perubahan Tingkat Pemahaman Kader Posyandu Terhadap Kesehatan Ibu Dan Anak Di Desa Kedungpandan Rini, Chylen Setiyo; Azzahra, Aulia; Aisyah Putri, Aprilia; Fitria Ayu Prayekti, Rahmatika
Jurnal Abdimas Berdaya : Jurnal Pembelajaran, Pemberdayaan dan Pengabdian Masyarakat Vol 8, No 1 (2025): Jurnal Abdimas Berdaya
Publisher : Universitas Islam Lamongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30736/jab.v8i1.1050

Abstract

Literature Study: The Effect of Butterfly Pea Flowers (Clitoria ternatea L.) on Human Health Chylen Setiyo Rini; Sukmawati Sukmawati; Ade Teti Vani; Ony Wibriyono Angkejaya; Mustar Mustar
Oshada Vol. 2 No. 1 (2025): Oshada Journal - February
Publisher : PT. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/1thek633

Abstract

This study aims to evaluate and summarize the findings from studies related to the effects of butterfly pea flowers (Clitoria ternatea L.) on human health, particularly those related to their therapeutic properties, including antioxidant, anti-inflammatory, neuroprotective, and relaxing effects. The research method used in this study is Systematic Literature Review (SLR). This approach was chosen because of its ability to systematically identify, evaluate, and summarize relevant research results on butterfly pea flowers. Article searches were conducted through academic databases such as PubMed, ScienceDirect, and Google Scholar, focusing on studies that discuss the effects of butterfly pea flowers on human health. Based on the analysis results of various existing studies, butterfly pea flowers show great potential in supporting human health. The content of bioactive compounds, such as flavonoids, anthocyanins, and alkaloids, provides various significant therapeutic benefits. Flavonoids and anthocyanins have strong antioxidant properties, play a role in fighting free radicals, and preventing oxidative damage that can cause degenerative diseases. In addition, these compounds have anti-inflammatory effects that are beneficial in managing inflammatory conditions such as arthritis, asthma, and heart disease. Butterfly pea flowers also show neuroprotective effects that can protect nerve cells, improve cognitive function, and protect the brain from neurodegenerative diseases such as Alzheimer's and Parkinson's. Alkaloids in butterfly pea flowers also have a relaxing effect that can help reduce anxiety and stress, and improve mental well-being. Although the results obtained are very promising, most studies are still limited to laboratory or animal trials, and further research, especially clinical trials in humans, is needed to confirm their effectiveness, proper dosage, and long-term safety.
Kelelahan Tenaga Kesehatan: Penurunan Kualitas Layanan di Indonesia Imamah, Siti Aliyatul; Rini, Chylen Setiyo; Puspitasari, Puspitasari; Mushlih, Miftahul
Manajemen Pelayanan Kesehatan Vol. 1 No. 1 (2024): Januari
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/mpk.v1i1.2923

Abstract

Burnout merupakan sindrom stres yang berhubungan dengan pekerjaan, seperti kelelahan emosional, sinisme dan ketidakefektifan profesional. Tujuan penelitian ini untuk mengetahui pengaruh Burnout Tenaga Kesehatan Terhadap Kualitas Pelayanan Di Rumah Sakit Bhayangkara Pusdik Sabhara Sidoarjo. Desain penelitian ini dilakukan secara eksperimental dengan menggunakan metode cross sectional study. Hasil penelitian menunjukkan adanya pengaruh burnout tenaga kesehatan terhadap kualitas pelayanan di Rumah Sakit Bhayangkara Pusdik Sabhara Sidoarjo. Pada kategori burnout cukup dan burnout sedang terdapat pengaruh yang signifikan dengan kualitas pelayanan, namun pada kategori burnout tinggi tidak terdapat pengaruh dengan kualitas pelayanan.
Korelasi Kadar Trombosit dengan parameter NS1Ag Pada Pasien Demam Berdarah: Studi Literatur Review Liany, Ayundah Novie; Lidyaningrum, Galuh Ajeng; Oktaruliawan, Veronika; Saputra, Eduwardo Roy; Nugroho, Rhenald Aditya; Wahyudi, Eko Bambang; Setyaputri, Nabila Hani; Putri, Wafiq Zahro; Anggraeni, Rifka Wahyu; Alhafiz, Rafaiz Filaili; Rini, Chylen Setiyo
Jurnal Teknologi Laboratorium Medik Borneo Vol. 5 No. 1 (2025): Jurnal Teknologi Laboratorium Medik Borneo
Publisher : Institut Teknologi Kesehatan dan Sains Wiyata Husada Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35728/jutelmo.v5i1.1871

Abstract

Dengue Fever (DHF) is a disease caused by infection with the Dengue virus, from the family Flaviridae and genus Flavivirus. Dengue virus consists of 4 serotypes. The virus is transmitted to humans through the bite of infected mosquitoes, especially Aedes Aegypti mosquitoes. In detecting dengue virus infection, laboratory examinations can be carried out such as platelet count, NS1Ag and dengue IgG IgM. The method used is a literature study by finding references from relevant journals. The results showed that there was a significant correlation between platelet levels and NS1Ag parameters in dengue hemorrhagic fever patients. And there is no relationship between clinical symptoms and NS1Ag parameters in dengue hemorrhagic fever patients. fever patients.
ANALYSIS OF DIFFERENCES IN TRIGLYCERIDE LEVELS BETWEEN TOBACCO SMOKERS AND ELECTRIC SMOKERS IN STUDENTS (ORMAWA) OF MUHAMMADIYAH UNIVERSITY OF SIDOARJO Mukarromah, Rizka Aisya; Hanum, Galuh Ratmana; Rohmah, Jamilatur; Rini , Chylen Setiyo
International Journal Multidisciplinary (IJMI) Vol. 2 No. 4 (2025): International Journal Multidisciplinary (IJMI)
Publisher : Antis-Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/ijmi.v2i4.328

Abstract

Objective: The aim of this study was to analyze the differences in triglyceride levels between tobacco smokers and e-smokers among students (ORMAWA) at Muhammadiyah University of Sidoarjo. Method: The design used in this research was quantitative with experimental tests using a cross-sectional approach. The population of this study included all male Ormawa students at Muhammadiyah University of Sidoarjo with the habit of smoking tobacco and e-smoking, totaling 532 students, with a sample size of 16 tobacco smokers and 16 e-smokers. The sampling method used is Quota non-probability sampling. This research was conducted at the hospital. Bhayangkara Pusdik Sabhara Porong in August 2024. The samples in the study were read using a DIALAB brand autolyzer with the colorimetric enzymatic method (GPO-PAP). Data from examination of triglyceride levels were analyzed statistically using the t-Independent test. Results: The results showed that there was no significant difference, namely 0.055 (p<0.05) between tobacco smokers and electronic smokers among students (Ormawa) at Muhammadiyah University of Sidoarjo. Novelty: This study provides comparative data on triglyceride levels between tobacco and electronic cigarette users within a specific university student organization population, which has not been widely studied in the Indonesian context.
Co-Authors AA Sudharmawan, AA Absari, Eki Puji Ade Teti Vani Aini, Aqiliyanti Nur Aisyah Putri, Aprilia Akbar, Aulia Rizky Fadhillah al-akbar, Wildan Alhafiz, Rafaiz Filaili Ambarani, Putri Yuli Andika Aliviameita Anggraeni, Rifka Wahyu Anugraheni Anugraheni Azzahra, Aulia Bayu Hari Prasojo Bima Arya Nugraha Devi Arvindani Masyitha Fifi Isti Tamtyas Fitria Ayu Prayekti, Rahmatika Fitria Eka Wulandari Fransiska Saputri Leing Galuh Ratmana Hanum Hartin, Ellyce Huesein, Ida Agustini Saidi Imamah, Siti Aliyatul Jamilatur Rohmah Jannah, Vita Wardah Nur Juliana, Tiara Karlia Hedit Tiana Kimberly, Bella Tasya Liany, Ayundah Novie Lidyaningrum, Galuh Ajeng Lindawati, Sari Liyaajul, Pratasyah Makhnunah, Makhnunah Miftahul Mushlih MUFIDAH, LAILATUL Mukarromah, Rizka Aisya Mustar Nisak, Khairun Nugroho, Rhenald Aditya NUR EFENDI Nuril Lutvi Azizah Oktaruliawan, Veronika Ony Wibriyono Angkejaya Pratiwi, Nova Linda Purwanti, Yanik Puspitasari Puspitasari Puspitasari Puspitasari Puspitasari Putri, Wafiq Zahro Rahmawati, Vifin Putri Ribangun Bamban Jakaria Saputra, Eduwardo Roy Sari, Azizah Krismonita Setyaputri, Nabila Hani SITI CHOLIFAH Sofi Rahayu, Bella Sukma Nilawati Sukmawati Sukmawati Tis’iyyah , Siti Nur Maghfiroh Tri Chahyani Rahmawati Putri Wahyudi, Eko Bambang Widyaningrum, Leni Yuroh Yeninastiti, Reny Zulfida Ainindiyah Putri Purwanto