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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Kimia Riset Jurnal Ilmiah Kedokteran Wijaya Kusuma THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Jurnal Ilmiah Soulmath : Jurnal Edukasi Pendidikan Matematika Jurnal Mandala Pharmacon Indonesia Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Medical Technology and Public Health Journal Jurnal Ners Sains dan Matematika Medicra (Journal of Medical Laboratory Science/Technology) Jurnal Abdimas Berdaya : Jurnal Pembelajaran, Pemberdayaan dan Pengabdian Masyarakat Jurnal Abdimas Kartika Wijayakusuma Indonesian Journal of Innovation Studies Procedia of Social Sciences and Humanities Prosiding SEMNAS INOTEK (Seminar Nasional Inovasi Teknologi) Jurnal Laboratorium Khatulistiwa International Journal Multidisciplinary Oshada Jurnal Teknologi Laboratorium Medik Borneo Jurnal Sains, Teknologi dan Kesehatan Manajemen Pelayanan Kesehatan Indonesian Journal Health Science and Medicine Jurnal Analis Kesehatan Kendari Academia Open

Chylen Setiyo Rini

Prodi Teknologi Laboratorium Medis, Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Sidoarjo

Author-ID : 3649951

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Dermatophyte Fungi Causing Tinea Unguium in Toenails of Builders in Bangkalan: Jamur Dermatophyte Penyebab Tinea Unguium pada Kuku Jari Kaki Pekerja Konstruksi di Bangkalan Aini, Aqiliyanti Nur; Rini, Chylen Setiyo; Mushlih, Miftahul; Puspitasari
Indonesian Journal on Health Science and Medicine Vol. 2 No. 2 (2025): Oktober
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i2.219

General Background: Tinea unguium is a nail plate infection commonly caused by dermatophyte fungi, frequently affecting individuals exposed to moist and contaminated environments. Specific Background: Builders are one of the occupational groups at high risk due to their constant contact with damp, dirty, and unhygienic surroundings. Knowledge Gap: Despite its prevalence, limited studies have focused on identifying specific dermatophyte species responsible for toenail infections among construction workers in Bangkalan, Madura. Aims: This study aimed to identify dermatophyte fungi causing Tinea unguium in the toenails of builders in Bangkalan. Results: Using a descriptive cross-sectional design with 28 purposively selected nail samples, findings revealed infections in 18 participants by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermatophyton floccosum, while 10 samples showed non-dermatophyte fungi (Aspergillus sp. and Scopulariopsis). Novelty: This research provides the first documentation of both dermatophyte and non-dermatophyte fungi associated with toenail infections among builders in this region. Implications: The findings underscore the need for occupational health awareness and preventive strategies targeting fungal nail infections among construction workers. Highlights: First identification of toenail dermatophytes in builders of Bangkalan. Found both dermatophyte and non-dermatophyte fungi species. Supports occupational health awareness for fungal infections. Keywords: Tinea Unguium, Dermatophyta, Toenails, Builders, Bangkalan

Uji Daya Hambat Ekstrak Segar Buah Pare (Momordica charantia Linn.) Terhadap Pertumbuhan Bakteri Klebsiella pneumoniae Dan Streptococcus pneumoniae rini, chylen setiyo
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Vol 6 No 1 (2023): The Journal Of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jmlt.v6i1.14494

Saluran pernapasan merupakan organ tubuh manusia yang banyak mengandung populasi bakteri (sekitar 13 spesies) yang dapat menjadi patogen seperti Klebsiella pneumoniae dan Streptococcus pneumoniae. Oleh karena itu, perlu adanya upaya mengendalikan Klebsiella pneumoniae dan Streptococcus pneumoniae dengan bahan dari bahan alam, salah satunya yaitu pare (Momordica charantia Linn). Buah pare (Momordica charantia Linn) telah terbukti khasiatnya sebagai obat yang memiliki kandungan senyawa seperti alkaloid, saponin, fenolik, streoid, flavonoid, dan tanin yang memiliki kemampuan sebagai antibakteri. Jenis penelitian ini adalah penelitian eksperimental. Dengan metode difusi kertas cakram atau Kirby-Bauer dengan 5 konsentrasi yaitu : 20%, 40%, 60%, 80%, 100%, dan digunakan antibiotik kloramfenikol sebagai (kontrol+). Pengujian dilakukan sebanyak 3 kali pengulangan. Data yang peroleh kemudian diuji menggunakan uji Anova one way dengan nilai signifikansi 0,05. Hasil penelitian menunjukkan bahwa ekstrak segar buah pare efektif terhadap pertumbuhan bakteri Klebsiella pneumoniae dan Streptococcus pneumoniae. Konsentrasi optimum pada bakteri Klebsiella pneumoniae diperoleh pada konsentrasi 100% dengan diameter sebesar 21,31 mm dan konsentrasi 80% dengan diameter sebesar 22,36 mm pada bakteri Streptococcus pneumoniae, sedangkan hasil uji ANOVA one way yang telah dilakukan terhadap diameter zona hambat bakteri Klebsiella pneumoniae dan Streptococcus pneumoniae diperoleh nilai signifikan p=0,000 dari hasil tersebut diketahui bahwa nilai <0,05 yang menunjukkan ada pengaruh yang nyata dari pemberian ekstrak segar buah pare terhadap pertumbuhan bakteri Klebsiella pneumoniae dan Streptococcus pneumoniae.

Identifikasi Mutasi RS7903146 pada Gen TCF7L2 pada Penderita Diabetes Tipa II di Wilayah Sidoarjo Huesein,; Mushlih, Miftahul; Rini, Chylen Setiyo; Hanum, Galuh Ratmana
Sains dan Matematika Vol. 8 No. 1 (2023): April, Sains & Matematika
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/sainsmat.v8n1.p28-31

Diabetes Mellitus Tipe 2 adalah gangguan sistem endokrin yang dipengaruhi oleh faktor genetik dan pilihan gaya hidup. Mutasi pada gen TCF7L2, khususnya pada rs7903146, telah erat terkait dengan T2DM karena efek gangguan pada sekresi insulin. Tujuan utama dari penelitian ini adalah mengidentifikasi mutasi pada gen TCF7L2 dalam populasi T2DM di Wilayah Sidoarjo. Sebanyak tujuh sampel digunakan dalam penelitian ini dengan mengaplikasikan teknik isolasi DNA, PCR, dan sekuensing. Sampel DNA secara khusus diperbanyak untuk menargetkan gen TCF7L2 selama 318 pasangan basa. Hasil penelitian ini menunjukkan ketiadaan mutasi pada rs7903146. Type 2 Diabetes Mellitus is an endocrine system disorder influenced by genetic factors and lifestyle choices. Mutations in the TCF7L2 gene, particularly at rs7903146, have been closely associated with T2DM due to their disruptive effects on insulin secretion. The primary objective of this study is to identify mutations in the TCF7L2 gene within the T2DM population of the Sidoarjo Region. A total of seven samples were utilized in this research, employing DNA isolation, PCR, and sequencing techniques. The DNA samples were specifically amplified to target the TCF7L2 gene over a stretch of 318 base pairs. The findings of this study indicate an absence of mutations at rs7903146.

Optimalisasi Edukasi dan Skrining Hemoglobin untuk Deteksi Dini Anemia pada Remaja Aliviameita, Andika; Puspitasari, Puspitasari; Setiyo Rini, Chylen; Rohmah, Jamilatur
Jurnal Abdimas Kartika Wijayakusuma Vol 6 No 3 (2025): Jurnal Abdimas Kartika Wijayakusuma
Publisher : LPPM Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jakw.v6i3.882

Anemia merupakan masalah kesehatan masyarakat dengan angka kejadian yang cukup tinggi di Indonesia, khususnya pada kalangan remaja. Anemia merupakan suatu kondisi medis yang ditandai oleh jumlah sel darah merah atau kadar hemoglobin yang mengalami penurunan dalam sirkulasi darah. Remaja dengan status gizi yang buruk memiliki kerentanan yang lebih tinggi terkena anemia. Remaja perempuan memiliki risiko terkena anemia lebih tinggi dibandingkan remaja laki-laki, salah satunya disebabkan oleh siklus menstruasi setiap bulan yang menyebabkan kehilangan darah secara rutin. Program pengabdian ini bertujuan untuk meningkatkan pemahaman dan kesadaran remaja terhadap pentingnya pencegahan anemia melalui edukasi dan pemeriksaan hemoglobin yang dilaksanakan di Sekolah Menengah Atas Negeri (SMAN) 1 Wonoayu. Sebanyak 25 siswa perempuan mengikuti edukasi dan pemeriksaan hemoglobin menggunakan metode Point of Care Testing (POCT). Hasil pemeriksaan menunjukkan bahwa 52% siswa memiliki kadar hemoglobin dalam kategori normal (>12 g/dL), sedangkan 48% lainnya mengalami kadar hemoglobin kategori abnormal (<12 g/dL) yang mengindikasikan adanya risiko anemia.

Effect of Delaying Urine at Room Temperature and Cold Temperature on the Number of Bacteria in Urinary Tract Infection Patients Rini, Chylen Setiyo
Jurnal Analis Kesehatan Kendari Vol. 7 No. 1 (2024): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 7 (1) Desember 2024)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v7i1.319

Urinary Tract Infection is an infection of the urinary tract, especially the kidneys, bladder, ureters and urethra which causes various microorganisms, generally bacteria. If urine is left for too long it will affect the validity of the examination results in supporting the diagnosis of an examination, especially UTI. The aim of this study was to determine the effect of delaying urine at room temperature and cold temperature on the number of bacteria in Urinary Tract Infection patients. The method used was Laboratory Experimental with Accidental Sampling sampling techniques in accordance with the inclusion criteria, totaling 5 samples. The results of the study at room temperature (20-25°C) (12.9 /ml). The data were analyzed statistically using the Friedman test, showing a significance value of P<0.05, namely 0.003, that there was an effect of delaying urine at room temperature and at cold temperatures on the number of bacteria in sufferers of Urinary Tract Infections (UTI).

Inhibitory Test of Turmeric Juice and Young Coconut Water Against Clostridium Perfringens Bakteri Bacteria: Uji Daya Hambat Air Perasan Kunyit dan Air Kelapa Muda Terhadap Bakteri Clostridium Perfringens Absari, Eki Puji; Rini, Chylen Setiyo
Indonesian Journal of Innovation Studies Vol. 12 (2020): October
Publisher : Universitas Muhammadiyah Sidoarjo

Medicinal plants are plants that contain ingredients that can be used for treatment and the active ingredients can be used as synthetic medicinal ingredients. One of the medicinal plants that is often used is turmeric (Curcuma longa). In addition, there is young coconut (Cocos nucifera) which is a plant native to the tropics, has water on the inside of young coconuts and can be consumed without going through processing. This study aims to determine the potential of the combination of turmeric juice with young coconut water in inhibiting Clostridium perfringens bacteria. This study used 5 concentrations, namely 25%, 50%, 75% and 100% and the combination of turmeric juice with young coconut water, namely 25%: 75%, 50%: 50% and 75%: 25%. The concentration of 100% extract of turmeric juice and young coconut water was the best concentration to form an inhibitory zone against the bacterium Clostridium perfringens of 32.66 mm and 14 mm.

Anti-Bacterial Effectiveness Test of Tamarind Leaf Extract (Tamarindus indica) and Turmeric Extract (Curcuma longa) against Klebsiella Pneumonia Bacteria: Uji Efektivitas Anti Bakteri dari Ekstrak Daun Asam Jawa (Tamarindus indica) dan Ekstrak Kunyit (Curcuma longa) terhadap Bakteri Klebsiella Pneumonia Juliana, Tiara; Rini, Chylen Setiyo
Indonesian Journal of Innovation Studies Vol. 12 (2020): October
Publisher : Universitas Muhammadiyah Sidoarjo

Tamarind and turmeric are used by the community to treat respiratory diseases and fever obtained at the Pandaan market. This study aims to determine the effectiveness of tamarind leaves and turmeric by maceration in inhibiting Klebsiella pneumoniae bacteria at various concentrations. Antibacterial activity test using Kirby-Bauer disc diffusion method with concentrations of 25%, 50%, 75%, and 100%. Tamarind and turmeric leaves used maceration extraction method by immersion using 96% ethanol as solvent. The positive control used was Penicillin while the negative control used was DMSO 10%. The concentrations of the samples used were: tamarind leaf extract with concentrations of 25%, 50%, 75%, and 100%; turmeric extract concentrations of 25%, 50%, 75%, and 100%; a combination of 25% tamarind leaf extract and 75% turmeric extract; a combination of 50% tamarind leaf extract and 50% turmeric extract; combination of 75% tamarind leaf extract and 25% turmeric extract. The total number of samples is 33 samples. The best inhibition was obtained from the results of the inhibition zone > 20 mm. Turmeric extract had the best antibacterial activity against the growth of Klebsiella pneumoniae bacteria at concentrations of 50%, 75%, and 100%. With each inhibition zone diameter of 21.5 mm; 29.83 mm ; and 33.16 mm. Based on the results of the Two Way ANOVA test with a 95% confidence level (p > 0.05), it was found that there was no significant effect between samples of tamarind leaf extract and turmeric extract on the growth of Klebsiella pneumoniae bacteria.

Inhibitory Test of Gambas Fruit Extract (Luffa Acutangula L.) on Clostridium Perfringens Bacteria with Maceration Method and Fresh Extract: Uji Daya Hambat Ekstrak Buah Gambas (Luffa Acutangula L.) Pada Bakteri Clostridium Perfringens dengan Metode Maserasi dan Esktrak Segar Makhnunah, Makhnunah; Rini, Chylen Setiyo
Indonesian Journal of Innovation Studies Vol. 12 (2020): October
Publisher : Universitas Muhammadiyah Sidoarjo

Plants have many chemical constituents. Utilization of plants as an alternative treatment in overcoming food poisoning, one of which is Gambas (luffa acutangula L) which contains flavonoids so that it can kill bacteria that attack the digestive system. This research was conducted in February-May 2021 and included an experimental study that aimed to determine the potential of maceration of Gambas fruit and fresh extract in inhibiting Clostridium perfringens bacteria at various concentrations. The antibacterial activity test was carried out by maceration method and fresh extract. This antibacterial potential is indicated by the form of a clear zone around the paper disk. This study used 4 concentrations, namely 25%, 50%, 75%, 100% and Penicillin as a positive control and aquadest as a negative control. Based on the non-parametric test using the Friedman test with a sign value (α <0.05) that is 0.008 which indicates that there are significant differences at various concentrations.

ANALISIS SUPPLY CHAIN MANAJEMEN GUNA OPTIMALISASI DISTRIBUSI IKAN BANDENG Jakaria, Ribangun Bamban; Rini, Chylen Setiyo
Prosiding SEMNAS INOTEK (Seminar Nasional Inovasi Teknologi) Vol. 1 No. 1 (2017): PROSIDING SEMNAS INOTEK Ke-I Tahun 2017
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29407/inotek.v1i1.436

Ikan bandeng adalah komoditi perikanan yang tersebar di beberapa lokasi tambak yang ada di sejumlah wilayah kecamatan di sidoarjo, dibandingkan dengan produk lain, ikan bandeng memiliki kekhasan yaitu umur penggunaan yang pendek serta tingkat kerentanan yang tinggi terhadap cuaca, sehingga diperlukan penanganan yang khusus dalam proses packaging dan penditribusiannya. Guna mempelajari konsep distribusi yang terintegrasi dari seluruh pihak pada setiap tahapan yang ada maka penelitian ini bertujuan untuk memaksimalkan kinerja supplier hingga customers dalam menghadirkan produk yang berkualitas guna terciptanya pemenuhan kebutuhan akan ikan bandeng oleh konsumen dengan biaya yang minimum dan service level yang maksimum. Metode yang digunakan adalah metode deskriptif analitis, yaitu merumuskan pola pemecahan masalah yang ada dan masa yang akan datang, berdasarkan data-data yang dikumpulkan untuk disusun, dijelaskan dan dianalisis. Sehingga akan memberikan solusi guna peningkatan potensi perikanan khususnya ikan bandeng di Sidoarjo.

Potensi Antibakteri Madu Multiflora dan Bee Pollen dari Lebah Madu Eropa (Apis mellifera) dalam Menghambat Pertumbuhan Cutibacterium acnes Jannah, Vita Wardah Nur; Rini, Chylen Setiyo
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.964

Jerawat adalah kondisi kulit di mana pori-pori tersumbat oleh minyak dan sel kulit mati, serta aktivitas bakteri C. acnes. Madu multiflora dan bee pollen merupakan produk lebah yang mengandung senyawa bioaktif dan memiliki sifat antibakteri. Penelitian ini menggunakan teknik difusi cakram dengan pengulangan sebanyak tiga kali (n=3) dengan konsentrasi 25% b/v, 50% b/v, 75% b/v, dan 100% b/v untuk madu dan bee pollen, serta kombinasi dengan perbandingan 1MM:3BP, 1MM:1BP, 3MM:1BP, tetrasiklin 50 mg/ml sebagai kontrol positif dan aquades steril sebagai kontrol negatif. Hasil menunjukkan bahwa madu, bee pollen, dan kombinasinya memiliki potensi antibakteri terhadap pertumbuhan C. acnes. Madu multiflora dan bee pollen memiliki penghambatan terkuat pada konsentrasi 100%, yaitu 27,71 mm (kategori kuat) untuk madu multiflora dan 18,26 mm (kategori sedang) untuk bee pollen. Kombinasi 3MM:1BP memberikan zona hambat tertinggi sebesar 29,81 mm (kategori kuat) dan menunjukkan hasil yang lebih efektif dibanding madu, bee pollen, dan kombinasi lainnya.

Co-Authors AA Sudharmawan, AA Absari, Eki Puji Ade Teti Vani Aini, Aqiliyanti Nur Aisyah Putri, Aprilia Akbar, Aulia Rizky Fadhillah al-akbar, Wildan Alhafiz, Rafaiz Filaili Ambarani, Putri Yuli Andika Aliviameita Anggraeni, Rifka Wahyu Anugraheni Anugraheni Azzahra, Aulia Bayu Hari Prasojo Bima Arya Nugraha Devi Arvindani Masyitha Fifi Isti Tamtyas Fitria Ayu Prayekti, Rahmatika Fitria Eka Wulandari Fransiska Saputri Leing Galuh Ratmana Hanum Hartin, Ellyce Huesein, Ida Agustini Saidi Imamah, Siti Aliyatul Jamilatur Rohmah Jannah, Vita Wardah Nur Juliana, Tiara Karlia Hedit Tiana Kimberly, Bella Tasya Liany, Ayundah Novie Lidyaningrum, Galuh Ajeng Lindawati, Sari Liyaajul, Pratasyah Makhnunah, Makhnunah Miftahul Mushlih MUFIDAH, LAILATUL Mukarromah, Rizka Aisya Mustar Nisak, Khairun Novita Arisanti Nugroho, Rhenald Aditya NUR EFENDI Nuril Lutvi Azizah Oktaruliawan, Veronika Ony Wibriyono Angkejaya Pratiwi, Nova Linda Purwanti, Yanik Puspitasari Puspitasari Puspitasari Puspitasari Puspitasari Putri, Wafiq Zahro Rahmawati, Vifin Putri Ribangun Bamban Jakaria Saputra, Eduwardo Roy Sari, Azizah Krismonita Setyaputri, Nabila Hani SITI CHOLIFAH Sofi Rahayu, Bella Sukma Nilawati Sukmawati Sukmawati Tis’iyyah , Siti Nur Maghfiroh Tri Chahyani Rahmawati Putri Wahyudi, Eko Bambang Widyaningrum, Leni Yuroh Yeninastiti, Reny Zulfida Ainindiyah Putri Purwanto

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