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All Journal Jurnal Periodic Jurusan Kimia UNP Jurnal Pendidikan dan Pembelajaran Kimia (JPPK) JURNAL EKSAKTA PENDIDIKAN (JEP) JURNAL PENDIDIKAN TAMBUSAI Walisongo Journal of Chemistry Eksakta : Berkala Ilmiah Bidang MIPA Pelita Eksakta G-Tech : Jurnal Teknologi Terapan Journal of Educational Chemistry (JEC) Edukimia Entalpi Pendidikan Kimia Ekasakti Jurnal Penelitian dan Pengabdian (EJPP) SCIENCE : Jurnal Inovasi Pendidikan Matematika dan IPA Jurnal Pijar MIPA Bhakti Nagori (Jurnal Pengabdian kepada Masyarakat) Entalpi Pendidikan Kimia Jurnal Pengabdian Pada Masyarakat Chimica Didactica Acta : Journal of Chemistry and Chemistry Education Jurnal Farmasi Indonesia Indonesian Journal of Chemical Science
Fajriah Azra
Universitas Negeri Padang
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Deskripsi Model Mental Peserta Didik Pada Materi Hukum-Hukum Dasar Kimia di SMAN 10 Padang Menggunakan Tes Diagnostik Four-Tier Aulia, Diva; Azra, Fajriah
Edukimia Vol 7, No 3 (2025): Edukimia - Vol. 07, Issue 03
Publisher : Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/ekj.v7.i3.a619

Abstract

Model mental adalah representasi seseorang dalam memahami dan menjelaskan suatu fenomena. Model mental peserta didik sangat penting diidentifikasi untuk mengetahui tingkat pemahaman, kesulitan dan miskonsepsi yang dialami peserta didik. Tujuan dari penelitian ini adalah mendeskripsikan model mental yang dimiliki peserta didik dalam memahami materi hukum-hukum kimia dasar di SMAN 10 Padang menggunakan tes diagnostik four-tier. Jenis penelitian ini adalah penelitian deskriptif dengan pendekatan kuantitatif. Pengambilan sampel menggunakan teknik cluster sampling, yaitu kelas X E8 dengan sampel sebanyak 36 orang. Instrumen yang digunakan dalam penelitian ini adalah tes diagnostik four-tier berbasis multirepresentasi kimia. Hasil penelitian menunjukkan bahwa peserta didik memiliki model mental Scientific Model dengan persentase sebesar 59,9%, Synthesis-Partial Understanding A sebesar 3,23%, Synthesis-Partial Understanding B sebesar 17,86%, Synthesis-Misconception sebesar 11,93%, dan Initial Model sebesar 6,87%. Sehingga model mental Scientific Model mendominasi model mental peserta didik. Berdasarkan persentase kesesuaian antara wawancara dengan tes diagnostik diperoleh sebesar 87,5%.
Molecular Docking Senyawa Bioaktif Tempuyung (Sonchus arvensis) Terhadap Reseptor ER-α Sebagai Inhibitor Kanker Payudara Asaumi, Suci; Azra, Fajriah; Kusnanda, Arif Juliari
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 18 No 1 (2026): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v18i1.414

Abstract

Breast cancer is a disease characterized by uncontrolled cell growth and division in breast tissue, leading to lump formation. The enzyme ER-α (Estrogen Receptor Alpha) plays a significant role in breast cancer development. This study aims to investigate the potential of bioactive compounds from the tempuyung plant (Sonchus arvensis) to inhibit the ER-α enzyme (PDB ID: 3ERT) through in silico methods for breast cancer drug development. The bioactive compounds in tempuyung are potential ER-α inhibitors. Methods used include Lipinski’s rule prediction, pharmacokinetics and toxicity analysis, and molecular docking simulations using MOE software. Among 25 screened bioactive compounds, luteolin showed binding to the active site of ER-α with a binding affinity of -6.34 kcal/mol and an RMSD of 0.77 Å, interacting with amino acids Glu 353, Gly 521, and Leu 346. These findings suggest luteolin as a promising candidate for breast cancer treatment.
Co-Authors Achie Keylla Ahmad Raisan R.P Ananda Putra Andromeda Andromeda Andromeda Anisa Pradila Annisa Ade Putri Annisa Annisa Annisa Khairani Putri Asaumi, Suci Asmiyunda Asmiyunda Aulia, Diva Aura, Selfi Monica AYU WULANDARI Azzahra, Siti Baehaqi Batri, Vani Mayfi Bayharti . Bayharti Bayharti Budhi Oktavia Cici Nur Awida Della Rezkyta Amanda Devi, Novi Arnita Dinda Purnama Kristy Dwi Finna Syolendra Edi Nasra Elfa Hayati Fadhillah, Trisa Faizah Qurrata Aini Fauzana Gazali Fitri Amelia Guspatni Guspatni Halizah, Wardah Hardeli - Hardeli Hardeli Indang Dewata Intan Nadya Istiva Depiyahani Jelita, Nabilah Putri Kristy, Dinda Purnama Kusnanda, Arif Juliari M. Iqbal S.G Ma'ruf, Hanif Sabawi Malinda, Tasya Mardani, Meri Aulia Maulidiana, Cindy Vikem Melati Wahyuni Meri Aulia Mardani Miftahul Khair Minda Azhar Minda Azhar Mirella Fonda Maahury Munifa Mahdiah Nadya UP Nagmah Putri Dinda Toni Nesha Putri Adi Nofri Yuhelman Norma Wahyunita Pera Meilita Pidiana, Dhea Putri Jelita, Nabilah Putri, Fitria Eka Qory Sidwa Jufri Rahadian Zainul ramadhan, muhammad_arvito Ramadhani, Fajri Randa Sagita Rifka Andani Riga Riga Riri Wahyuni Robiatul Adawiyah Sagita, Randa Sari, Trisna Kumala Selfi Monica Aura Septya Anggraini Shelvy WA Silvinia Humaira Silvira Rahmi Suryelita Suryelita . Syafriadi, Riko Syamsi Aini Tessa Faradilla Ulfa Autafia Umar Kalmar Nizar Vani Mayfi Batri Viona Maharani Yeri Mardesi Yerimadesi Zonalia Fitriza