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All Journal Tropical Medicine Journal Jurnal Ilmiah Farmasi Acta Interna : The Journal of Internal Medicine Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Simetris Medula JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Majalah Farmaseutik Jurnal Mandala Pharmacon Indonesia Berita Kedokteran Masyarakat Jurnal Farmasi Indonesia Jurnal Penyakit Dalam Indonesia Indonesian Journal of Pharmacology and Therapy

Rizka Humardewayanti Asdie

Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran, Kesehatan Masyarakat Dan Keperawatan Universitas Gadjah Mada/ RSUP Dr. Sardjito, Yogyakarta

Author-ID : 3661099

Computer Science & IT Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Rasionalitas Penggunaan Antibiotik Empirik dan Definitif pada Pasien Sepsis di Intensive Care Unit RSUP. Dr. Sardjito Mayada Rakhmima Karizki; Ika Puspitasari; Rizka Humardewayanti Asdie
Majalah Farmaseutik Vol 17, No 3 (2021)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v1i1.62045

Sepsis merupakan penyakit mengancam jiwa berupa disfungsi organ yang berhubungan dengan infeksi. Hingga saat ini sepsis menjadi sebab utama kematian di Intensive Care Unit (ICU). Penanganan yang diberikan pada 1 jam pertama akan menentukan keberhasilan terapi selanjutnya, salah satunya antibiotik. Penggunaan antibiotik yang rasional berkaitan dengan luaran klinik pasien. Tujuan dari penelitian ini adalah mengetahui hubungan rasionalitas antibiotik dengan luaran klinik pasien sepsis di ICU RSUP Dr. Sardjito tahun 2018-2019. Penelitian dilakukan secara observasional-analitik dengan desain kohort retrospektif. Dari 59 pasien yang memenuhi kriteria inklusi, diperoleh 138 antibiotik dengan rincian 112 antibiotik empirik dan 26 antibiotik definitif. Kriteria Gyssens digunakan untuk evaluasi rasionalitas antibiotik dilanjutkan analisis hubungan rasionalitas antibiotik dan variabel perancu dengan luaran klinik menggunakan uji Chi-square atau Fisher's Exact. Masing-masing uji menggunakan tingkat kepercayaan sebesar 95%. Persentase penggunaan antibiotik secara rasional (kategori 0) sebesar 13,6% (23 antibiotik) untuk antibiotik empirik dan 21,6% (8 antibiotik) untuk antibiotik definitif. Total persentase antibiotik tidak rasional (kategori I-V) dari antibiotik empirik dan definitif secara berurutan sebesar 86,4% (146 antibiotik) dan 78,4% (29 antibiotik). Terdapat hubungan yang tidak signifikan antara rasionalitas antibiotik dengan luaran klinik pasien sepsis di ICU RSUP Dr. Sardjito tahun 2018-2019 (p>0,05).

Relationship Between Appropriateness of Empirical Antibiotics Based on ATS/IDSA with Clinical Outcome and Length of Stay in ICU (Intensive Care Unit) Patient with Sepsis Pneumonia Muhammad Luthfi Aziz; Ika Puspita Sari; Rizka Humardewayanti Asdie
Jurnal Ilmiah Farmasi Vol. 18 No. 1 (2022): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol18.iss1.art9

Background: In ICU (Intensive Care Unit), sepsis is the most common cause of death, with pneumonia being the most common source of infection. The management of sepsis pneumonia is determined by the therapy used. One of the supporting aspects in the successful treatment of sepsis pneumonia is appropriate empiric antibiotic therapy.Objective: Determine the relationship between the appropriateness of empirical antibiotics based on ATS/IDSA (American Thoracic Society/ The Infectious Disease Society of America) with clinical outcome and LOS (Length Of Stay) in ICU patients with sepsis pneumonia.Method: An observational study with a retrospective cohort design in ICU patients with sepsis pneumonia from January 2019-December 2020 at RS X Jakarta. The study involved 99 patients who were divided into two groups based on appropriate and inappropriate with ATS/IDSA. Data were analyzed using bivariate and multivariate for reducing the confounding factor.Results: The appropriateness of empirical antibiotics was found to be appropriate in 48.48% (48 patients), while 51.52% (51 patients) were inappropriate with ATS/IDSA. There was a relationship between empirical antibiotic appropriateness and clinical outcome (p=0.042; RR=1.430; 95%CI=1.039-1.969) based on the chi-square test, but no relationship with LOS (p=0.629) based on the Mann Whitney test. The multivariate analysis showed that there were no confounding factors affecting the clinical outcome (p>0.05).Conclusion: There is a relationship between empirical antibiotic appropriateness based on ATS/IDSA with clinical outcomes but not related to the length of stay in sepsis pneumonia patients in the ICU.Keywords: sepsis pneumonia, antibiotic empiric, clinical outcome, LOS IntisariLatar belakang: Sepsis merupakan penyebab kematian terbanyak di ICU (Intensive Care Unit), dengan sumber infeksi tertinggi adalah pneumonia. Keberhasilan pengobatan sepsis pneumonia bergantung pada terapi yang diberikan. Pemberian terapi antibiotik empirik yang sesuai merupakan salah satu faktor penunjang keberhasilan pengobatan sepsis pneumonia.Tujuan: Mengetahui hubungan kesesuaian antibiotik empirik berdasarkan ATS/IDSA (American Thoracic Society/ The Infectious Disease Society of America) dengan outcome klinik dan lama waktu rawat pasien sepsis pneumonia di ICU.Metode: Penelitian observasional dengan rancangan kohort retrospektif pada pasien ICU dengan diagnosis sepsis pneumonia periode 1 Januari 2019-31 Desember 2020 di RS X Jakarta. Penelitian melibatkan 99 pasien yang terbagi dalam kelompok sesuai dan tidak sesuai ATS/IDSA. Data dianalisis dengan uji bivariat serta multivariat untuk mereduksi variabel pengganggu.Hasil: Kesesuaian antibiotik empirik diperoleh sebesar 48,48% (48 pasien) telah sesuai dan 51,52% (51 pasien) tidak sesuai ATS/IDSA. Berdasarkan hasil uji chi-square terdapat hubungan kesesuaian antibiotik empirik dengan outcome klinik (p=0,042; RR=1,430; 95%CI=1,039-1,969) dan berdasarkan uji mann whitney tidak terdapat hubungan antara kesesuaian antibiotik empirik dengan lama waktu rawat (p=0,629). Hasil analisis multivariat menunjukkan tidak ada faktor pengganggu yang mempengaruhi outcome klinik (p>0,05).Kesimpulan: Kesesuaian antibiotik empirik berdasarkan ATS/IDSA pada pasien sepsis pneumonia di ICU memiliki hubungan dengan outcome klinik namun tidak berhubungan dengan lama waktu rawat.Kata kunci: sepsis pneumonia, antibiotik empirik, outcome klinik, lama waktu rawat

Faktor – Faktor Risiko yang Berpengaruh terhadap Kejadian Demam Tifoid pada Orang Dewasa Arief Rakhman, Rizka Humardewayanti, Dibyo Pramono
Berita Kedokteran Masyarakat (BKM) Vol 25, No 4 (2009)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Background: In 2000 it was estimated that typhoid fever had caused more than 21.6 million morbidity and 216,510 deaths. In Indonesia typhoid fever is still very endemic. Morbidity in semi rural areas reaches 157/ 100,000 in rural population and increases to 810/100,000 in urban population. At District of Bulungan morbidity caused by typhoid fever is still relatively very high. The major cases of typhoid fever of patients hospitalized at RSUD dr. H. Soemarno Sosroatmodjo happen to age group of > 14 years old (63.84%).Objective: To identify risk factors associated with the incidence of typhoid fever in adults.Method: The study was observational and used a case control study design. There were 260 samples, comprising 130 cases and 130 control matched based on age and gender. Location of the study was dr. H. Soemarno Sosroatmodjo Hospital at District of Bulungan, Province of Kalimantan Timur. Cases were hospitalized adult patients diagnosed having typhoid fever based on clinical symptoms and laboratory examination. Control consisted of new patients diagnosed not having typhoid fever. Data analysis used chi square, Odds Ratio (OR) and logistic regression.Result: The result of multivariate analysis showed that only the variable of not washing hands using soap before having meal was associated with the incidence of typhoid fever in adults (p=0.002; OR=1.625; 95%CI=1.497 – 4.602). Whereas the variables of eating out, history of typhoid in the family, availability of clean water and ownership of toilet that did not meet health requirements had no association with the incidence of typhoid fever.Conclusion: The habit of not washing hands using soap before having meal was factor associated with the incidence of typhoid fever in adults at District of Bulungan. Therefore health promotion on clean and healthy lifestyle should be introduced to all community, particularly washing hands using soap before having meal.Keywords: typhoid fever, adults, risk factors, case control

Comparison of Red Cell Distribution Width Values towardsMortality in Adult and Elderly Hospital-Acquired PneumoniaPatients in Dr. Sardjito Hospital Sari, Desty Gusti; Asdie, Rizka Humardewayanti; Retnowulan, Heni
Jurnal Penyakit Dalam Indonesia Vol. 8, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Introduction. Hospital-acquired pneumonia (HAP) is a major cause of morbidity and mortality. Red cell distribution width (RDW) is associated with mortality in patients with septic shock and community-acquired pneumonia (CAP). However, little is known about the effect of elevation of RDW value on mortality in HAP patients, especially in the elderly population who have a worse prognosis. This study aimed to determine the proportion of adult and elderly HAP patients who have an increase in RDW value and the relation between the increase in RDW value to the risk of mortality in HAP patients during hospitalization. Methods. A cross-sectional and retrospective cohort study was performed using medical records of inpatients diagnosed with HAP in RSUP Dr. Sardjito Yogyakarta from March 2014 until March 2015. The study’s sample was chosen by a consecutive sampling method. The data were analyzed with chi-square and logistic regression. Results. During the study period, a total of 106 patients were diagnosed with HAP with fulfilled the inclusion and exclusion criteria. Sixty-eight subjects (64.15%) survived, and 38 subjects (35.84%) died. The median RDW value was 15.3% (range 11.4 – 29.8%). The proportion of adult and elderly HAP patients toward the increase in RDW value was not statistically significant (p=0.331). Factor contributing to the increase of RDW value was haemoglobin (p<0.001; RR 5.617 (95% CI 2.294 – 13.756) and thrombocyte (p=0.002; RR 4.471 (95% CI 1.720 – 11.625). There was a proportion difference between RDW value and HAP mortality (p=0.043), but it was not statistically significant. Factor contributing to the increase of HAP mortality was sepsis (p<0.001; RR 7.121 (95% CI 2.599-19.509)) and leucocyte (p=0.031; RR=3.077 (95% CI 1.108 – 8.546)). Conclusions. There is no proportion difference in increasing RDW value between adult and elderly HAP patients. We also found that RDW value was not contributing to make the increase in mortality among HAP patients. However, this study found other factors, including haemoglobin and platelet level which correlated with the increase of RDW. We also found that sepsis and high leukocyte levels are significantly correlated with the incidence of mortality among HAP patients.

HALP Score as a Prognostic Factor of Mortality in Septic Patients at Dr. Sardjito General Hospital Anjani, Alindina; Asdie, Rizka Humardewayanti; Wijisaksono, Doni Priambodo
Acta Interna The Journal of Internal Medicine Vol 11, No 1 (2021): Acta Interna The Journal of Internal Medicine
Publisher : Faculty of Medicine Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/actainterna.94631

Background. Sepsis is still an important health problem with a high mortality rate, an average of 44.5% in Asian countries. An easy and early biomarker is needed to determine the prognosis of sepsis. The HALP inflammation index can be used to predict mortality in malignancy conditions, yet has not been studied for sepsis.Objective. This study aimed to determine whether HALP score has a prognostic value for mortality in non malignant septic patients at Dr. Sardjito General Hospital.Methods. This was a retrospective cohort study of septic patients admitted to Internal Medicine wards between January 1, 2016 and December 31, 2018. The prognostic accuracy was evaluated by assessing the area under the receiver operating characteristic (AUC) curve. The primary outcome was mortality at the end of hospitalization. Results:. There were 125 adult patients, 104 with high HALP score (≥54,34), 21 low HALP score (<54,34), 45 patients died (36%). Patients with low HALP score were significantly at risk of death (p=0.007, OR 3.66, 95% CI 1.38-9.68) than high HALP score. Logistic regression was used to account for potential confounding factors. Low HALP score (p = 0.004, OR 4.74, 95% CI 1.63-13.76), sepsis diagnosed with quick SOFA (p = 0.006, OR 0.25, 95% CI 0.09-0.68), and multiple infections (p = 0.011, OR 2.93, 95% CI 1.28-6.73) were significantly associated with mortality in sepsis patients at Dr. Sardjito General Hospital.Conclusion. HALP score has a prognostic value of mortality in adult patients with sepsis at Dr. Sardjito General Hospital

Evaluasi Hubungan Rasionalitas Penggunaan Antibiotik Terhadap Clinical Outcome dan Lama Perawatan Pada Pasien Dewasa Dengan Infeksi Saluran Kemih Nabila, Lathifa; Sari, Ika Puspita; Asdie, Rizka Humardewayanti; Purwaningtyastuti, Eni
Majalah Farmaseutik Vol 20, No 1 (2024)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v20i1.76845

Infeksi saluran kemih (ISK) adalah salah satu penyakit infeksi yang sering terjadi di masyarakat dan ditandai dengan adanya mikroorganisme di dalam urin. Penelitian ini bertujuan untuk mengetahui hubungan antara rasionalitas penggunaan antibiotik terhadap clinical outcome dan lama perawatan pada pasien dewasa dengan ISK. Penelitian ini menggunakan studi observasional metode kohort retrospektif. Data penelitian diambil dari rekam medik pasien dari bulan Januari – Desember 2020 dan dilakukan di RSUP Dr. Sardjito Yogyakarta. Jumlah pasien yang masuk kriteria inklusi sebanyak 139 pasien dan didapatkan 149 regimen antibiotik empirik dan 13 regimen antibiotik definitif pada penelitian ini. Evaluasi rasionalitas penggunaan antibiotik empirik maupun definitif berdasarkan klasifikasi Gyssens menunjukkan sebanyak 101 regimen (67,8 %) antibiotik empirik dan 10 regimen (76,9 %) antibiotik definitif yang rasional, 48 regimen (32,2 %) antibiotik empirik dan 3 regimen (23,1 %) antibiotik definitif yang tidak rasional. Rasionalitas penggunaan antibiotik empirik pada pasien dewasa dengan ISK berpengaruh signifikan secara statistik (p = 0,042) dalam meningkatkan clinical outcome, sedangkan kesesuaian penggunaan antibiotik definitif tidak berpengaruh secara statistik (p = 0,289) dalam meningkatkan clinical outcome pasien. Rasionalitas penggunaan antibiotik empirik dan definitif pada pasien dewasa dengan ISK tidak berpengaruh.

Amikasin: Profil Penggunaan pada Pasien Dewasa Rawat Inap di RSUP Dr.Sardjito Yogyakarta berdasarkan Fungsi Ginjal Utami, Esti Dyah; Puspitasari, Ika; Asdie, Rizka Humardewayanti; Lukitaningsih, Endang; Dahesihdewi, Andaru
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 13 No. 1 (2021): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Amikacin is used for serious infection treatment, with a nephrotoxicity incidence of 3-13%. More than 90% of amikacin is excreted through the renal in unchanged form, thus accumulation may occur in renal dysfunction. This research is aimed to determine the amikacin usage profiles based on the patient’s renal function and evaluate the association between a renal function with hospital discharge conditions and length of stay (LOS). This research was conducted by collecting the medical record data of adult inpatients at Dr. Sardjito Hospital treated with amikacin in 2020. A Chi-Square test was used to determine the proportion differences between 2 groups of patients with different renal functions, and the relationship of renal function with discharge condition and LOS. The majority of 78 subjects had normal renal function, with a diagnosis of mixed infection. Amikacin was used as definitive therapy, as an antibiotic combination, with a median dosage of 14.3mg/kgBW/day, 12 hours interval, and 5 days duration. Results showed that the CrCl, infection type, comorbid, amikacin intervals and duration had significantly different proportions (p<0.05) between patients with normal renal function and those with renal dysfunction. Renal function was positively associated with the patient’s discharge condition, but not with LOS.

Direct Medical Costs of Diabetes and the Foot Ulcer Outpatients in A General Hospital, Yogyakarta Untari, Eka Kartika; Andayani, Tri Murti; Yasin, Nanang Munif; Asdie, Rizka Humardewayanti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.90615

Background: In addition to the financial burden that Diabetes Mellitus (DM) places on diabetics and their families due to the complications of Diabetic Foot Ulcers (DFU), treatment costs are escalating. Along with the costs associated with diabetic impairments, direct medical costs may contribute significantly to the financial burden of diabetes.Objectives: This study aimed to determine expenditures associated with DFU, identify cost-influencing factors, and compare the costs of patients with DFU and those without ulcers.Methods: To achieve this objective, this study employed a cross-sectional design and included 198 medical records of DM patients who met the following criteria: age range of 18 to 60 years; type 1 or type 2 DM; receipt of anti-diabetics; payment information; absence of autoimmune or end-stage chronic disease; and absence of corticosteroid. The significance of the cost difference between DFU and non-ulcer patients was evaluated using parametric and non-parametric tests as well as linear regression analysis to determine the cost-influencing factors.Results: This study included 188 patients with type 2 diabetes and ten patients with type 1 diabetes. A total of 131 people with diabetes did not have ulcers, while 67 had a history of DFU. The average direct medical expenses for patients with DFU are IDR 760,146.32, compared to IDR 542,51.24 for patients without ulcer.Conclusion: The presence of ulcers and glycemic conditions had an effect on the direct costs; insulin use also affected the direct costs. The direct costs of diabetic ulcer were significantly higher than non-ulcer, and they were predominantly affected by insulin prescribing.

Ambroxol Therapy as an Antibiofilm Candidate in Diabetic Ulcer Patients Wahyuddin, Munifah; Sari, Ika Puspita; Asdie, Rizka Humardewayanti; Nuryastuti, Titik
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 1 (2025): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i1.791

Patients with diabetic ulcers are susceptible to infection because the tissue in their extremities is constantly exposed to various pathogenic bacteria, so biofilm formation plays an important role in developing the disease. Based on previous studies, ambroxol can inhibit the formation of biofilm bacteria. The purpose of this study was to identify biofilm-forming bacteria, prove that ambroxol has the potential to inhibit and eradicate biofilms formed by bacteria in diabetic ulcers and analyse the potential of ambroxol in eradicating biofilms formed by bacteria in diabetic ulcer patients based on PEDIS and SEM scores. The method used was a 96-well microtiter plate assay (MtPA) with crystal violet and MTT staining techniques, a test using human samples with a quasi-experimental method with sampling carried out by nonprobability sampling. The samples used were diabetic ulcer patients with culture results forming biofilms. The results obtained identified 3 clinical isolates that formed biofilms with 100% Gram-negative bacteria, including two isolates of Pseudomonas aeruginosa and one isolate of Escherichia coli with the ability to form biofilms are moderate. Ambroxol effectively inhibits and eradicates 50% of biofilms formed by diabetic ulcer bacteria at a minimum concentration of 1 mg/ml. Based on the PEDIS score and SEM images of diabetic ulcer patients, there was a decrease in the PEDIS score in each patient, with an average score of 2. Several studies have demonstrated that combining Ambroxol with antimicrobials can synergistically enhance the antibiotic's efficacy against biofilms. The co-administration of Ambroxol with other antimicrobial agents represents a promising approach to improving antibiotic effectiveness. Nevertheless, careful consideration must be given to the concentration of Ambroxol used.

Evaluation of empirical antibiotic usage and cost analysis of patients with nosocomial pneumonia in ICU of RSUP Dr. Sardjito, yogyakarta Minar Paskah Lianti Manik; Rizka Humardewayanti Asdie; Ika Puspitasari
Indonesian Journal of Pharmacology and Therapy Vol 1 No 2 (2020)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.573

The rationality of antibiotic usage has an implication on the therapeutic quality and antimicrobial resistance control. Qualitative and quantitative evaluation of this rationality becomes one quality indicator of hospitals' antimicrobial resistance programs. Therefore, this study aims to determine the relationship between the rationality of antibiotic usage with clinical outcomes and the total cost in nosocomial pneumonia patients treated in the Intensive Care Unit (ICU). The method used was descriptive-analytic observational research with a cross-sectional design analysis, and data were collected retrospectively from the medical and financial record of patients with inclusion criteria. The data were then analyzed descriptively using the Gyssens flowchart. Fisher statistical test was conducted to analyze the relationship between rationality data and therapeutic outcomes. Furthermore, the Mann Whitney statistical test was conducted to examine the relationship between rationality data and the cost, while the paired t-test was conducted to analyze the resistance pattern. The results showed that antibiotic usage in patients with nosocomial pneumonia at the ICU of RSUP Dr. Sardjito was irrational and rational by 30.21% (29 regimens) and 69.79% (67 regimens) respectively. This rationality has a relation with clinical outcome based on Fisher test with p-value = 0.001 (p <0.05). Considering these results, the antibiotics cost both in the rational and irrational category has no significant difference with the p-value of 0.90 (p<0.05).

Co-Authors Abu Tholib Aman Adi Irawan Agus Barmawi Andaru Dahesihdewi Anjani, Alindina Anton Pratama Chairani, Farahdina Denia Yuni Wulandari Desty Gusti Sari Djoko Wahyono Djoko Wahyono Doni Priambodo Doni Priambodo Doni Priambodo Wijisaksono Eka Kartika Untari Elma Viorentina Sembiring Endang Estriningsih Endang Lukitaningsih Enita Rakhmawati Kurniaatmaja Esti Dyah Utami Estriningsih, Endang Faisal Heryono Farahdina Chairani Hanny Hafiar Hari Kusnanto Hemi Sinorita Hemi Sinorita Hemi Sinorita Hemi Sinorita Ika Puspita Sari Ika Puspita Sari Ika Puspita Sari Ika Puspitasari Ika Puspitasari Ika Puspitasari Iswandi Darwis Juvita Kurniawan Maemonah, Maemonah Mayada Rakhmima Karizki Minar Paskah Lianti Manik Minar Paskah Lianti Manik Muhammad Luthfi Nabila, Lathifa Nanang Munif Yasin Nanang Munif Yasin Neema Putri Prameswari Pebriati Sumarningsih Pebriati Sumarningsih Pratama, Anton Purwaningtyastuti, Eni Retnowulan, Heni Rina Hudayani Rizki Rahmawati Rosylianti Rosylianti Sari, Desty Gusti Silvikarina Erfanti Dewi Halim Soebagjo Loeheri Sumarningsih, Pebriati Titik Nuryastuti Titik Rahayu Titik Rahayu Tri Hartati Tri Hartati, Tri Tri Murti Andayani Trisno Agung Wibowo Wahyuddin, Munifah Wijisaksono, Doni Priambodo Wulandari, Denia Yuni Yanri WIjayanti Yanri Wijayanti Subronto Yuli Mawarti

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