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All Journal Jurnal SOLMA Hydrogen: Jurnal Kependidikan Kimia Jurnal Senopati : Sustainability, Ergonomics, Optimization, and Application of Industrial Engineering Jurnal Abdimas Kartika Wijayakusuma CHEDS: Journal of Chemistry, Education, and Science Jurnal Pijar MIPA Indonesian Journal of Chemical Science
Effendi, Meilisa Rusdiana Surya
Universitas Bojonegoro
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Education Engineering Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Physics Social Sciences Other

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DAYA INHIBISI EKSTRAK PEGAGAN (CENTELLA ASIATICA) TERHADAP AKTIVITAS ENZIM XANTIN OKSIDASE SEBAGAI ANTIHIPERURISEMIA SECARA IN VITRO Surya Efendi, Meilisa Rusdiana
CHEDS: Journal of Chemistry, Education, and Science Vol 8, No 2 (2024)
Publisher : Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/cheds.v8i2.10168

Abstract

Asam urat diproduksi tubuh sebagai bahan sisa metabolisme yang mengandung purin. Asam urat merupakan produk oksidasi xantin yang dikatalisis oleh enzim xantin oksidase. Dalam istilah medis, penurunan kadar asam urat dalam darah dilakukan dengan menambahkan inhibitor untuk menahan aktivitas enzim xanthine oksidase, salah satunya dengan mengonsumsi allopurinol. Penelitian ini dilakukan untuk mengetahui senyawa metabolit sekunder yang terkandung dalam ekstrak etanol serta daya hambatnya terhadap enzim xantin oksidase. Hasil penelitian menunjukkan bahwa alkaloid, flavonoid, saponin dan polifenol ditemukan pada ekstrak etanol pennywort. Pada konsentrasi 100 ppm daya inhibisi ekstrak etanol daun pennywort sebesar 75%, begitu pula Allopurinol 10 ppm sebesar 75%. Untuk memperoleh kemampuan inhibisi dengan 1 tablet allopurinol diperlukan daun pennywort sebanyak 378,62 g (menggunakan pelarut etanol).
Analisa Terapan Teknologi Pengeringan Higienis pada Cabai Rawit Kering untuk Stabilitas Pasokan di Luar Panen Raya Farahdiansari, Ardana Putri; Surya Effendi, Meilisa Rusdiana; Stighfarrinata, Rizky; Maghfiroh, Amalia Ma'rifatul
Jurnal SENOPATI : Sustainability, Ergonomics, Optimization, and Application of Industrial Engineering Vol 7, No 1 (2025): Jurnal SENOPATI Vol 7, No 1
Publisher : Institut Teknologi Adhi Tama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31284/j.senopati.2025.v7i1.7793

Abstract

This study aims to analyze the application of hygienic design to utilize the excess supply of cayenne pepper during the peak harvest season, where many harvests are not absorbed into the market. Meanwhile, during the harvest in the off-season, the amount of chili harvest is unable to meet market demand, resulting in a spike in the price of cayenne pepper. The spike in the price of cayenne pepper has quite high variability, where the lowest price is IDR 15,000.00 but the highest price can reach IDR 100,000.00. With the implementation of the use of the DrySter Eco House drying house, farmers can store excess harvest results when prices drop and process them as dried cayenne pepper supplies and then sell them when the supply of fresh cayenne pepper on the market is low and the selling price is high. The DrySter Eco House greenhouse system relies on solar energy as the main source. This approach utilizes a greenhouse structure equipped with temperature and humidity control technology, as well as air circulation assistance that utilizes energy from solar panels to maintain optimal conditions during the drying process. By using greenhouse technology, the water content of cayenne pepper can be reduced significantly in a shorter time compared to conventional open drying methods. The use of renewable energy not only reduces operational costs, but also supports environmental sustainability and is able to maintain the quality of dried cayenne pepper. This study includes trials and measurements of several variables, such as temperature and drying time, to compare the results of conventional drying with drying using the DrySter Eco House prototype. With the supply of cayenne pepper from prospective harvest waste, farmers can stabilize the supply of chili during the off-season while also obtaining additional income from the sale of dried chili.
Antioxidant Activity and Phytochemical Screening of Ethanol Extract from Ruellia napifera Leaves Efendi, Meilisa Rusdiana Surya; Anisa, Zuffa; Setyaningrum, Dyah; Trisnawati, Ade
Jurnal Pijar Mipa Vol. 20 No. 5 (2025)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v20i5.9300

Abstract

Exploration of the chemical profile and antioxidant properties of ethanol extract derived from Ruellia napifera leaves is very important, considering the usefulness of these leaves for use in natural therapy products. This research investigates the identification of secondary metabolite compounds and the antioxidant activity of ethanol extract from Ruellia napifera leaves. The objectives are to determine the types of secondary metabolite compounds present and to evaluate the antioxidant potential using the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging method. Ethanol extracts were prepared using the maceration method at durations of 24 hours. Phytochemical tests revealed the presence of flavonoids, alkaloids, saponins, and steroids. Antioxidant activity was measured through IC50 values, indicating the extract’s ability to inhibit 50% of the DPPH radicals. The IC50 values obtained were 10.66 μg/mL. For comparison, vitamin C as a positive control exhibited an IC50 of 2.49 μg/mL. These results suggest that the Gempur Batu leaf extract has strong antioxidant potential. These findings suggest that this extract from Ruellia napifera leaves holds potential for developing natural antioxidant-based therapeutic products or herbal medicine formulations.
Pengolahan Limbah Kaca sebagai Bahan Filler Paving Block untuk Pencegahan Cemaran DAS Bengawan Solo Farahdiansari, Ardana Putri; Effendi, Meilisa Rusdiana Surya; Ashari, Faisal
Jurnal SOLMA Vol. 13 No. 3 (2024)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v13i3.16396

Abstract

Background: Bengawan Solo merupakan sungai sepanjang ±300 km di pulau Jawa yang dimanfaatkan sebagai sumber daya air untuk kebutuhan domestik masyarakat. Namun, pencemaran akibat limbah rumah tangga, termasuk kaca, mengancam kelestarian ekosistem sungai. Limbah kaca yang tidak terurai dapat merusak ekosistem dan membahayakan masyarakat. Penelitian ini bertujuan memberikan solusi inovatif dengan memanfaatkan limbah kaca sebagai bahan filler paving block untuk mencegah pencemaran tersebut. Metode: Mitra dalam kegiatan adalah PKK (Pemberdayaan Kesejahteraan Keluarga) Desa Kalirejo yang lokasinya terletak di bantaran DAS (Daerah Aliran Sungai) Bengawan Solo dengan jumlah anggota 120 ibu rumah tangga. Pelaksanaan kegiatan dilaksanakan pada 4 September 2024 dengan metode pendampingan langsung di lokasi mitra, yang meliputi tahapan wawancara, observasi, pelatihan, pendampingan, dan evaluasi. Hasil: Dari kegiatan ini, diperoleh hasil bahwa terjadi peningkatan kesadaran mitra untuk mengurangi pembuangan limbah kaca serta pentingnya pengelolaan limbah kaca secara aman di lingkungan DAS Bengawan Solo, dari 60% menjadi 98%. Dengan adanya fasilitas penampungan limbah kaca rumah tangga serta mesin penghancur limbah kaca, maka keinginan mitra dalam mendaur ulang limbah kaca menjadi paving block meningkat secara signifikan dari 25% menjadi 95%. Kesimpulan: masyarakat termasuk mitra PKK cenderung kurang menyadari pentingnya pengelolaan limbah kaca. Hal ini disebabkan kurangnya pengetahuan mengenai bahaya limbah kaca bagi lingkungan, serta kesulitan dalam menampung dan mengelola limbah kaca secara bijak.
IDENTIFIKASI METABOLIT SEKUNDER DAN UJI INHIBISI XANTIN OKSIDASE EKSTRAK DAUN KERSEN (Muntingia calabura L) Surya Efendi, Meilisa Rusdiana; Trisnawati, Ade
CHEDS: Journal of Chemistry, Education, and Science Vol 6, No 2 (2022)
Publisher : Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/cheds.v6i2.6272

Abstract

Penelitian ini bertujuan untuk mengetahui kandungan senyawa golongan metabolit sekunder dan menguji kemampuan daun kersen dalam menghambat xantin oksidase. Daun kersen diekstraksi dengan cara dimaserasi menggunakan pelarut etanol 70% kemudian diuji secara kualitatif kandungan senyawa metabolit sekundernya. Pengujian penghambatan xantin oksidase dilakukan menggunakan spektrofotometer pada panjang gelombang 290 nm dengan kondisi pH 7,5, konsentrasi substrat xantin 0,15 mM. dan suhu inkubasi 30oC. Uji penghambatan pada Alopurinol memiliki nilai IC50 sebesar 0,50 µg/mL sedangkan ekstrak daun kersen memiliki nilai IC50 sebesar 1,17 µg/mL. Identifikasi secara kualitatif kandungan senyawa metabolit sekunder pada ekstrak etanol daun kersen mengandung flavonoid, saponin, tanin, steroid dan alkaloid.
Synthesis of Colorimetric Sensor for Cyanide Detection with Iron(III) Chloride reagent Using Sol Gel Method with Smarthphone Combination Rohsaita, Amalia; Thohir, Muhammad Bakhru; Surya Efendi, Meilisa Rusdiana; Kusumaning Tiyas, Windi Pangesti; Nursaida, Marta Citra
Hydrogen: Jurnal Kependidikan Kimia Vol. 12 No. 3 (2024): June-July 2024
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v12i3.11887

Abstract

Sensor untuk mendeteksi ion sianida (CN - ) telah berhasil dilakukan dengan metode sol-gel menggunakan prekursor tetraetil ortosilikat dan pereaksi FeCl3. Penelitian ini bertujuan untuk mengetahui kondisi optimal sintesis, kondisi optimal sensor, menentukan LoD dan LoQ. Sintesis dilakukan dengan mencampurkan prekursor dengan pelarut etanol. Selanjutnya ditambahkan H2O, Triton X-100, reagen dan katalis ke dalam campuran. Variasi yang dilakukan adalah konsentrasi reagen dan waktu penuaan terbaik. Hasil sensor dinyatakan dalam nilai Euclidean Distance (ED) titik Merah-Hijau-Biru (RGB) yang diperoleh. Kondisi optimal untuk penyensoran dilakukan dengan memvariasikan waktu kontak. Pada sintesis sol gel konsentrasi reagen terbaik diperoleh pada konsentrasi 0,1 M dan waktu penuaan terbaik adalah 4 hari. Penentuan kondisi sensor optimal terjadi pada waktu 30 detik dengan batas pencucian 120 detik. Validasi metode sensor menghasilkan linearitas pada rentang konsentrasi 100 – 1000 ppm dengan nilai R 2 sebesar 0,9984. LoD dan LoQ masing-masing sebesar 65,45 ppm dan 218,16 ppm. Karakterisasi sensor menggunakan spektrofotometer FTIR dari bilangan gelombang 4000 sampai 400 cm-1. Spektrum IR yang dihasilkan menunjukkan keberhasilan dalam sintesis sol-gel, karena pada penelitian ini SiO2 muncul pada bilangan gelombang sekitar 433 cm-1. Setelah tahap sensor dengan merendam sensor pada analisa CN - 0,01 M dan CN - 0,1 M tidak ada tanda-tanda munculnya gugus Fe-S pada bilangan gelombang 4000-400 cm-1, karena daerah serapannya berada pada 380- 311 cm -1.
The Electrical Behaviour Study on Saltwater Batteries in Various Electrolyte Concentrations and Cross-Sectional Areas Anisa, Zuffa; Mubarokah, Lailatul; Rusdiana SE, Meilisa; Setyaningrum, Dyah
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 2 (2025): April 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i2.14591

Abstract

A study has been conducted to analyze the effect of various electrolyte concentrations and cross-sectional areas on voltage and current in batteries using the galvanic cell method (voltaic cells). This study aims to determine the electrolyte concentration and electrode cross-sectional area that provide optimal effects on voltage, current, and power in batteries. Variations in NaCl electrolyte concentration of 1 M; 3 M; 5 M; 7 M; and 9 M as electrolytes and variations in the cross-sectional area of Cu-Al 5 cm2, 10 cm2, 15 cm2, 20 cm2, 25 cm2 as electrodes. From these tests, the optimal voltage value was obtained at a concentration of 7 M and a cross-sectional area of 25 cm2 with a value of 0.73 V, the optimal current value at a concentration of 7 M and a cross-sectional area of 25 cm2 with a value of 19.99 mA, and the optimal power value at a concentration of 7 M and a cross-sectional area of 25 cm2 with a value of 14.593 mwatts. The larger the cross-sectional area of the electrode, the greater the electrical energy produced. The optimum concentration of electrolyte greatly influences the value of the electrical power produced.
Synthesis AuNPs Using Moringa oleifera Extract and Potential Study as Colorimetric Microplastic Detection Thohir, Muhammad Bakhru; Setyaningrum, Dyah; Efendi, Meilisa Rusdiana Surya; Saputra, Arya Ananda; Nursaida, Marta Citra
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 3 (2025): June 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i3.16603

Abstract

Nanoparticles are multipurpose materials that have been utilized in the medical, energy, and environmental monitoring fields. The advantage of nanoparticles is that they have unique physicochemical properties such as surface area, optical activity, and surface modifiability. One of the important uses of nanoparticles is for environmental monitoring. This is because the surface of nanoparticles can be modified, and with their small size, they can reach analytes in difficult matrices. However, conventional synthesis methods of nanoparticles have been unsustainable. Therefore, the synthesis of AuNPs using bioreductors was considered urgent. The aim of this research was to determine the optimum conditions for the synthesis of AuNPs with Moringa oleifera (MO) as a bioreductor to obtain AuNPs-MO, to characterize the synthesized AuNPs-MO, and to study the application of AuNPs-MO for monitoring microplastic pollutants. This research was conducted through the stages of extraction, determination of optimum conditions, characterization, and literature study of the potential of AuNPs-MO as a detector. Determination of optimum conditions was carried out by applying variations in pH and precursor-reducing agent ratio. The optimal pH was found to be 6, and the optimal volume ratio was 15:5 (mL). Characterization of AuNPs-MO was conducted using FTIR and PSA. The FTIR spectra showed identical absorption patterns for AuNPs synthesized with bioreductants, and the particle size was found to be 61.15 nm. In addition, microplastics were detected using AuNPs both directly, through surface modification with proteins, and indirectly, with the assistance of acetone. From this series of experiments, satisfactory results were obtained.
Qualitative and Quantitative Identification of Alcohol using the Conway Microdiffusion Method and Gas Chromatography-Flame Ionization Detector (GC-FID) on Evidence at the East Java Polda Bidlabfor Lailatul Mubarokah; Meilisa Rusdiana Surya Efendi
Indonesian Journal of Chemical Science Vol. 13 No. 2 (2024): Indonesian Journal of Chemical Science
Publisher : Prodi Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Driving under the influence of alcohol is a safety issue of increasing public concern. Alcohol is a factor in many categories of accidents. Investigations and resolution of legal problems need to be followed up until the case is resolved in court. Items in the form of physical evidence related to the crime scene, victims and suspects need to be identified. Based on this, one of the topics raised in this research includes the results of identification and analysis of criminal cases involving alcohol consumption which were tested qualitatively and quantitatively, so that evidence can be determined during the investigation process as to whether there is alcohol content in it. In the process of qualitative identification of alcohol content, it is carried out using the Conway Microdiffusion method which states that the urine evidence is positive for alcohol, which is indicated by the color changing to green. Meanwhile, identification of alcohol levels in evidence is carried out using a Gas Chromatography -Flame lonization Detector (GC-FID). Analysis of the alcohol content in the evidence stated that the presence of ethanol was 0.0352%.
Pelatihan Pembuatan Eco-enzyme serta Aplikasinya dalam Pembuatan Sabun Mandi Padat untuk Ibu-Ibu PKK Desa Glagahwangi Kabupaten Bojonegoro Efendi, Meilisa Rusdiana Surya; Putri, Yustika Arida; Arifin, Putri Autika; Ardiansyah, Ananda Dimas; Prasetya, Giraldi Eka
Jurnal Abdimas Kartika Wijayakusuma Vol 6 No 4 (2025): Jurnal Abdimas Kartika Wijayakusuma
Publisher : LPPM Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jakw.v6i4.986

Abstract

Kegiatan pengabdian kepada masyarakat ini dilaksanakan di Desa Glagahwangi, Kabupaten Bojonegoro, dengan tujuan meningkatkan pemanfaatan limbah organik rumah tangga melalui pelatihan pembuatan eco-enzyme dan aplikasinya dalam sabun mandi padat. Limbah organik yang tidak terkelola sering menimbulkan pencemaran lingkungan dan bau tidak sedap. Eco-enzyme, hasil fermentasi sederhana dari limbah organik, gula, dan air, memiliki potensi sebagai bahan pembersih alami dan ramah lingkungan. Pelatihan dilaksanakan dengan metode partisipatif melalui ceramah, demonstrasi, dan praktik langsung oleh ibu-ibu PKK. Data diperoleh melalui observasi, dokumentasi, dan wawancara untuk mengevaluasi pemahaman dan keterampilan peserta. Hasil kegiatan menunjukkan peningkatan signifikan dalam pemahaman tentang pengolahan limbah organik serta keterampilan membuat sabun mandi padat berbasis eco-enzyme. Program ini juga mendorong kesadaran lingkungan dan membuka peluang usaha rumahan. Dengan demikian, kegiatan ini berkontribusi pada pengurangan limbah organik sekaligus peningkatan kesejahteraan masyarakat melalui pemberdayaan berbasis lingkungan.
Co-Authors Amalia Ma’rifatul Maghfiroh Ardana Putri Farahdiansari Ardiansyah, Ananda Dimas Arifin, Putri Autika ASHARI, FAISAL Dyah Setyaningrum, Dyah Kusumaning Tiyas, Windi Pangesti Lailatul Mubarokah Lailatul Mubarokah Nursaida, Marta Citra Prasetya, Giraldi Eka Putri, Yustika Arida Rizky Stighfarrinata Rohsaita, Amalia Saputra, Arya Ananda Thohir, Muhammad Bakhru Trisnawati, Ade