Article Per Year (5 Year)
p-Index From 2021 - 2026
2.681
P-Index
This Author published in this journals
All Journal Pharmacon Jurnal ABDIMAS-HIP Pengabdian Kepada Masyarakat Prosiding University Research Colloquium Jurnal Ilmiah Kesehatan Borneo Journal of Pharmacy Baktimu : Jurnal Pengabdian Kepada Masyarakat
Dwi Bagus Pambudi
Universitas Muhammadiyah Pekajangan Pekalongan
Humanities Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Nursing Public Health Social Sciences Other

Published : 21 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 21 Documents
Search

 1   2   3 
Skrining Fitokimia Dan Penetapan Nilai SPF Ekstrak Etanol Kulit Buah Kakao (Theobroma cacao L.) Nisa'ul Khoiriyah; Dwi Bagus Pambudi; S Slamet; St. Rahmatullah
Prosiding University Research Colloquium Proceeding of The 16th University Research Colloquium 2022: Mahasiswa (Student Paper Presentation)
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kulit buah kakao (Theobroma cacao L.) mengandung senyawa flavonoid dan polifenol yang berfungsi sebagai photoprotective serta memiliki aktivitas antioksidan yang dapat melindungi permukaan kulit dari radikal bebas yang disebabkan oleh paparan radiasi sinar matahari. Penelitian ini bertujuan untuk mengetahui kandungan metabolit sekunder yang dapat berpengaruh terhadap nilai Sun Protection Factor (SPF) serta mengetahui nilai SPF dari ekstrak etanol kulit buah kakao. Penelitian ini menggunakan metode reaksi dengan pereaksi warna serta metode spektrofotometri UV-Vis untuk mengetahui nilai SPF dari ekstrak etanol kulit buah kakao. Nilai SPF ekstrak etanol kulit buah kakao dianalisis dengan persamaan Mansur. Hasil penelitian ini menunjukkan ekstrak etanol kulit buah kakao mengandung flavonoid, alkaloid, tannin, dan fenol. Ekstrak etanol kulit buah kakao pada konsentrasi 1.250, 2.500, 3.750, dan 5.000 ppm menunjukkan nilai SPF secara berturut-turut 14,88 ± 0,19, 26,74 ± 0,18, 35,10 ± 0,14, 38,70 ± 0,05.
Efektivitas Dressing Madu Terhadap Waktu Penyembuhan Luka Pada Kelinci (Galur Wistar ) Firman Faradisi; Nurul Aktifah; Dwi Bagus Pambudi
Prosiding University Research Colloquium Proceeding of The 16th University Research Colloquium 2022: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Luka merupakakn kerusakan pada lapisan epidermis atau lebih dalam yang diakibatkan perubahan patofisiologi yang menjadi asal utama terjadi luka. Nutrisi merupakan salah satu factor yang mempengaruhi proses penyembuhan luka. Karbohidrat merupakan nutrisi yang digunakan sel sebegai energy dalam proses penyembuhan luka. Alternatif dressing yang dapat digunakan adalah madu. Penelitian ini bertujuan untuk mengevaluasi evektivitas dressing menggunakan madu. Uji t-dependent (paired sample t test) digunakan untuk mengetahui keefektivan dressing. Dressing madu diperoleh nilai t hitung sebesar 5.547 (p = 0,001 < 0,05). Artinya pemberian madu efektif dalam penyembuhan luka. Hasil ini menunjukan bahwa pemberian madu mempercepat penyembuhan luka.
Uji Aktivitas Antifungi Ekstrak Lengkuas (Alpinia galanga (L) Willd) Terhadap Jamur Candida albicans Dengan Metode Sumuran Galuh Surya Cahyaningrum; S Slamet; W Wirasti; Dwi Bagus Pambudi
Prosiding University Research Colloquium Proceeding of The 16th University Research Colloquium 2022: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Lengkuas merupakan tanaman yang memiliki banyak khasiat, salah satunya sebagai antijamur. Lengkuas (Alpinia galanga (L) Willd) merupakan tanaman yang mengandung senyawa metabolit sekunder seperti alkaloid, fenol, tannin, saponin, flavonoid dan terpenoid yang memiliki fungsi sebagai fungisida alami. Penelitian ini bertujuan untuk mengetahui ekstrak (Alpinia galanga (L) Willd) dapat mengetahui efektifitas antifungi terhadap jamur Candida albicans. Metode penelitian yang digunakan dalam penelitian ini adalah metode sumuran pada uji aktivitas antijamur ekstrak lengkuas (Alpinia galanga (L) Willd) dan metode maserasi untuk ekstraksi lengkuas (Alpinia galanga (L) Willd). Analisis data yang diperoleh menunjukkan ekstrak lengkuas (Alpinia galanga (L) Willd) memiliki aktivitas antifungi pada konsentrasi 5% memiliki daya hambat sebesar 9,10 mm, konsentrasi 10% memiliki daya hambat sebesar 10,16 mm dan konsentrosi 15% memiliki daya hambat sebesar 11,43 mm terhadap jamur Candida albicans yang merupakan kategori kuat.
Pengaruh Penggunaan Pati Umbi Porang (Amorphophallus Oncophyllus Prain Ex Hook.F) Sebagai Bahan Pengikat Pada Tablet Ekstrak Etanol Kulit Buah Menteng Jihan Amrina Rosyada; St. Rahmatullah; Dwi Bagus Pambudi; Wulan Agustin Ningrum
Prosiding University Research Colloquium Proceeding of The 16th University Research Colloquium 2022: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Porang (Amorphophallus oncophyllus Prain ex Hook.f) merupakan salah satu jenis talastalasan yang mengandung pati yang dapat digunakan sebagai bahan pengikat pada formulasi tablet. Kulit buah menteng mengandung zat yang bermanfaat sebagai antioksidan. Tujuan dari penelitian ini yaitu untuk mengetahui pengaruh penggunaan pati umbi porang (Amorphophallus oncophyllus Prain ex Hook.f) sebagai bahan pengikat pada tablet ekstrak etanol kulit buah menteng. Penelitian ini menggunakan metode granulasi basah dengan konsentrasi pati 5%, 10% dan 15%. Evaluasi pada tablet yang dilakukan yaitu uji organoleptis, keseragaman bobot dan ukuran, kekerasan, kerapuhan serta uji waktu hancur. Analisis data dilakukan secara kualitatif dengan mengacu pada literatur persyaratan yang telah ditetapkan oleh BPOM RI. Kedua formula memenuhi syarat dalam uji evaluasi granul dan tablet. Hasil yang optimal yaitu terdapat pada formula III dengan konsentrasi amilum 15 %. Evaluasi granul meliputi uji kadar air 1,00 %, uji waktu alir 1,46 detik, uji sudut diam 14,57º, dan uji kompresibilitas 5,06 %. Evaluasi tablet meliputi uji organoleptis dengan bentuk bulat cembung dan warna putih tulang, uji keseragaman bobot dengan rata-rata 694,5 mg, uji keseragaman ukuran dengan diameter 1,80 cm dan tebal 0,80 cm, uji kekerasan 4,2-4,6 kg, uji kerapuhan 0,05 %, dan uji waktu hancur 11 menit 53 detik. Hasil yang diperoleh menunjukkan bahwa penggunaan pati umbi porang (Amorphopallus oncophyllus Prain ex Hook.f) sebagai bahan pengikat berpengaruh terhadap sifat fisik tablet ekstrak etanol kulit buah menteng (Baccaurea racemosa (Reinw. ex Blume) Müll. Arg.)
Optimasi Emulgator pada Sediaan Body Scrub Ekstrak Etanol Daun Bakau Hitam (Rhizophora mucronata Lam.) Lia Khusnul Maulidah; Dwi Bagus Pambudi; St. Rahmatullah; Urmatul Waznah
Prosiding University Research Colloquium Proceeding of The 16th University Research Colloquium 2022: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sediaan Body Scrub ekstrak etanol daun bakau hitam (Rhizophora mucronata Lam.) merupakan pemanfaatan dari limbah daun bakau hitam sebagai produk kosmetik. Suatu sediaan Body Scrub akan baik apabila menggunakan emulgator yang sesuai.Tween 80 merupakan suatu emulgator yang bersifat hidrofilik, sedangkan Span 80 merupakan emulgator dengan gugus lipofilik lebih dominan. Tween 80 dan Span 80 akan membentuk emulsi yang baik dan tidak terpengaruh pada perubahan elektrolit maupun pH. Tujuan dari penelitian ini yaitu untuk mendapatkan formula yang optimal dengan variasi konsentrasi emulgator pada sediaan body scrub ekstrak etanol daun bakau hitam (Rhizophora mucronata Lam.). Sediaan Body Scrub dievaluasi fisik meliputi uji organoleptis, uji homogenitas, uji pH, uji daya sebar, uji viskositas dan uji stabilitas. Hasil dari analisis formula yang paling optimal yaitu formula 5 dengan perbandingan Tween dan Span 1 : 10.
Efektivitas Farmakologi Senyawa Aktif Tumbuhan Mangrove Yang Hidup Di Indonesia Dwi Bagus Pambudi; H Haryoto
Jurnal Ilmiah Kesehatan Vol. 15 No. 1 (2022): Jurnal Ilmiah Kesehatan
Publisher : Universitas Muhammadiyah Pekajangan Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48144/jiks.v15i1.625

Abstract

Mangroves are ecologically important plants in marine habitats that occupy the coastlines of several countries. Apart from their primary ecological importance, various parts of mangroves are widely used in traditional medicine and are claimed to be effective in treating various diseases. At present, no comprehensive effort has been made to compile and critically analyze the published literature in view of its ethnopharmacological utility. This review aims to provide a comprehensive overview of the biodiversity and distribution of mangrove plants, ethnopharmacology, phytochemical profiles, and pharmacological activities of mangrove plants used as traditional medicine in Indonesia. The method used is by using literature studies from the Science Direct, Pubmed, and Google Scholar database. Result show that In Indonesia, there are 33 types of mangrove species, all of which are traditionally used as medicine, which are spread throughout the archipelago in Indonesia. Bioactive compounds obtained from mangrove plants include polyphenols, flavonoids, alkaloids, carotenoids, tannins, saponins, steroids, amino acids, carbohydrates, proteins, vitamins etc. This review also shows that the pharmacological activities of mangrove plants in general include antimicrobials (such as antibacterial, antiviral and antifungal), anti-inflammatory, anti-ulcer, antidiarrheal, anticancer, antidiabetic, anti-HIV, antinociceptive, hepatoprotective, antiarthritis, analgesic, antioxidant and cytotoxic activities.
Formulasi Sediaan Tablet Ekstrak Daun Talas (Colocasia esculenta (L.) Schott.) Dengan Variasi Kadar Polivinil Pirolidon (PVP) Sebagai Bahan Pengikat St Rahmatullah; Dwi Bagus Pambudi; Yulian Wahyu Permadi; Nurul Hikmah
Jurnal Ilmiah Kesehatan Vol. 16 No. 1 (2023): Jurnal Ilmiah Kesehatan
Publisher : Universitas Muhammadiyah Pekajangan Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48144/jiks.v16i1.1429

Abstract

Taro leaves (Colocasia Esculenta (L.) Schott.) contain alkaloids, saponins, tannins, flavonoids and polyphenols. Utilization of taro leaves requires new innovations by developing ways of making tablets, which increase the convenience of use through more comfortable use and more stable storage compared to liquid pharmaceutical preparations or suspensions. The aim of this study was to determine the effect of the comparison of variations of Polyvinylpyrrolidone (PVP) binder on the physical properties of granules and tablets and to obtain the optimum formula. Tablets were made by wet granulation process with 1%, 3% and 5% PVP. Granules were tested for water content, flow time test, angle of repose and tapping. The resulting tablets were then tested for their physical properties. Research result; Weight uniformity with 5% PVP fulfills the physical requirement of 600 g. Size uniformity fulfills the physical requirements with a yield of 2.91 mm. Hardness with 3% PVP meets the physical requirements of 5.95 kg. Fragility meets the physical requirements of 1% PVP, namely 0.4%. The disintegration time with 1% PVP met the physical requirements, namely 7.88 minutes. The results stated  that variations in the concentration of the PVP binder could be formulated into tablets and the tablet binder resistance was measured which met the requirements of the best tablet physical properties. Optimal formulation is achieved in formula III with binder containing 5% PVP.
Indonesian anti-inflammation herbs mechanism: mini review Nuniek Nizmah. F Mochtar; Eko Mugiyanto; Wirasti wirasti; Vanesa Maharani; Novel Umarella; Hilda Fitria Wulandari; St. Rahmatullah; Widyastuti Handayani; Dwi Bagus Pambudi; Riska Kurnia Oktaviani; Achmad Vandian Nur; Yuliah Wahyu Permadi; Ainun Muthoharoh; Thanh-Hoa Vo; Muh. Nur Khoiru Wihadi
Jurnal Ilmiah Kesehatan Vol. 16 No. 2 (2023): Jurnal Ilmiah Kesehatan
Publisher : Universitas Muhammadiyah Pekajangan Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48144/jiks.v16i2.1453

Abstract

This mini-review aims to provide an overview of some commonly used anti-inflammatory herbs in Indonesia. Inflammation is a complex physiological response that plays a role in various diseases, and herbal remedies have been used traditionally in Indonesian culture for their potential anti-inflammatory properties. We utilize Portal Garuda as the primary database for searching herbs with anti-inflammatory activity using the keyword "anti-inflamasi”. The selected herbs discussed in this review include turmeric (Curcuma longa), ginger (Zingiber officinale), clove (Syzygium aromaticum), and cinnamon (Cinnamomum sp.). These herbs have been reported to possess anti-inflammatory effects through various mechanisms, such as inhibition of pro-inflammatory enzymes and cytokines, antioxidant activity, and modulation of immune responses. Moreover, these herbs have also demonstrated safety profiles in traditional use. However, further scientific research is needed to elucidate the specific bioactive compounds responsible for their anti-inflammatory effects and to determine the optimal dosages and formulations for therapeutic use. The exploration of Indonesian anti-inflammatory herbs could contribute to the development of natural and affordable options for managing inflammatory conditions, complementing conventional treatments, and promoting overall health and well-being.
Pelatihan Pembuatan Pembalut Kain di Desa Proto Barat, Kecamatan Kedungwuni, Kabupaten Pekalongan Dwi Bagus Pambudi; Mahdanya Puteri; Indah Aulia; Khoerurrohim Khoerurrohim; Imroatul Maghfiroh; Gigih Setianto
Jurnal ABDIMAS-HIP Pengabdian Kepada Masyarakat Vol 4 No 2 (2023): Jurnal ABDIMAS-HIP Pengabdian Kepada Masyarakat
Publisher : LPPM Akbid Harapan Ibu Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37402/abdimaship.vol4.iss2.260

Abstract

Cloth pads are a necessity during menstruation. According to research, disposable sanitary napkins currently in use are carcinogenic and contain harmful substances that have the potential to cause dangerous diseases for the reproductive organs. This training aims to find out how to manufacture, use and advantages of eco-friendly cloth sanitary napkins. These innovative cloth pads are made of fleece, diadora, cotton, waterproof, thread, sewing needle, ruler, scissors, pencil/ballpoint pen/marker, and adhesive. The method used with several steps, such as the presentation of material on how to make cloth pads and the advantages and disadvantages of cloth pads, product making begins with pattern making to the sewing stage, and the conclusion of the activity. The result is a product in the form of eco-friendly cloth pads.
Test on the Antioxidant Activities of Methanol Extract of Bidara Leaves (Ziziphus spina-christi L.) using the DPPH Radical Immersion Method Dwi Bagus Pambudi; Nuniek Nizmah Fajriyah; Vidiah Rizka Shalekhah
Borneo Journal of Pharmacy Vol. 3 No. 1 (2020): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v3i1.1242

Abstract

Bidara (Ziziphus spina-christi L.) is a tropical tree originating from Sudan in which it is commonly known as "Nebeq" in Saudi Arabia. It is of a bioactive compound - a flavonoid compound, which is the potential to be used as an antioxidant. It is capable of inhibiting any cell damages caused by free radicals. This study aimed to measure the activities of the free radicals in methanol extracts of Z. spina-christi leaves. The process of extracting the Z. spina-christi leaves was carried out through the maceration method using methanol as a solvent. The qualitative analysis of chemical compounds with certain eluents using thin-layer chromatography (TLC) was purposely to determine the groups of active compounds in extracts. The measurement of antioxidant activities was carried out using the 1,1-Diphenyl-2-picryl Hidrazyl (DPPH) immersion method in which absorption was measured at a maximum wavelength of 513 nm. The results showed that the methanol extract of Z. spina-christi leaves had a very weak antioxidant activity with the IC50 value of 466.804 μg/ml. The results of the bioautographic profile showed the presence of flavonoid compounds, phenols, saponins, and tannins.
Co-Authors Abdurrachman Abdurrachman Achmad Vandian Nur, Achmad Vandian Ainun Muthoharoh Dina Salwa Atiqi Eko Mugiyanto Firman Faradisi Galuh Surya Cahyaningrum Gigih Setianto Haryoto Haryoto Hilda Fitria Wulandari Imroatul Maghfiroh Indah Aulia Isy Annisa Jihan Amrina Rosyada Khoerurrohim Khoerurrohim Khusna Santika Rahmasari Lia Khusnul Maulidah Mahdanya Puteri Muh. Nur Khoiru Wihadi Muhammad Syahrian Huda Muti' Sya'bania Nadia Salsabila Ulfa Naila Iva Amalina Putri Sulaiman Ningrum, Wulan Agustin Nisa'ul Khoiriyah Novel Umarella Nuniek Nizmah Fajriyah Nuniek Nizmah. F Mochtar Nur Mufidah Nurul Aktifah Nurul Hikmah Riska Kurnia Oktaviani Roro Ayu S Slamet Slamet, Slamet St Rahmatullah St. Rahmatullah Thanh-Hoa Vo Umi Hanifah Urmatul Waznah Vanesa Maharani Vidiah Rizka Shalekhah Widyastuti Handayani Wirasti Yuliah Wahyu Permadi Yulian Wahyu Permadi