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Journal : Tropical Medicine Journal

Spatial Analysis on Vulnerability to Dengue Hemorrhagic Fever in Kotabaru Subdistrict, Jambi Municipality, Jambi Province Suhermanto -; Tri Baskoro Tunggul Satoto; Barandi Sapto Widartono
Tropical Medicine Journal Vol 2, No 1 (2012): Tropical Medicine Journal
Publisher : Pusat Kedokteran Tropis

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3054.118 KB) | DOI: 10.22146/tmj.4313

Abstract

Introduction: High incidence of DHF in Kotabaru Subdistrict was high even endemic in all villages. Utilization of Geographical Information System technology integrated with the wide of settlement land, the density of Aedes sp, maya index, resistance and transovarial of virDen, got a picture or map vulnerable areas prone event of DHF in Kotabaru Subdistrict.Objectives: This study to map areas vulnerable to dengue hemorrhagic fever is based on the highest incidence of DHF in Kotabaru Subdistrict, Jambi Municipality.Methods: This study is an observational survey with cross sectional design. The variable of the study was population density, the wide of settlement land, the density of Aedes sp. population, rainfall, vector vulnerability, and transovarial of virDen.Results: The result showed population density had no correlation to Dengue Hemorrhagic Fever (DHF) incidence, whereas the wide of settlement land (p=0.004) and population density of Aedes sp. (p=0.001) influenced DHF incidence. The number water containers controllable sites (89%) and percentage of Maya Index (p=<0.001) was high influenced DHF incidence. Rainfall not influenced DHF incidence. The vector resistance not influenced the high of DHF incidence and the high of DHF incidence was not influenced by transovarial of virDen. The high vulnerability to DHF in Kotabaru Subdistrict occurred in 2 villages and the intermediate vulnerability happens in 4 villages. The area with intermediate vulnerability generally have direct border to the village with high vulnerability category.Keywords: Spatial, Maya Index, Resistance, DHF
DYNAMICS OF DENGUE HEMORRHAGIC FEVER INCIDENCE WITH SPATIO-TEMPORAL APPROACH IN MARITENGNGAE SUBDISTRICT, SIDENRENG RAPPANG DISTRICT, SULAWESI SELATAN PROVINCE, IN 2008-2009 I Made Swastika; Tri Baskoro Tunggul Satoto; Anis Fuad
Tropical Medicine Journal Vol 1, No 2 (2011): Tropical Medicine Journal
Publisher : Pusat Kedokteran Tropis

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1733.507 KB) | DOI: 10.22146/tmj.4570

Abstract

Introduction: Dengue Hemorrhagic Fever (DHF) causes 40% of world population at risk for infection, and 50 million people get infection with as many as 24,000 die every year. Incidence rate in Indonesia, particularly in Maritengngae Subdistrict, Sidenreng Rappang District, is increasing and needed to be controlled. Disease distribution has not been documented regionally. The dynamics of the incidence,that comprises the characteristics of the patient, environmental conditions, susceptibility of mosquitoes resulted from insecticide use, transovarial infectivity, and the incidence pattern were unknown.Objectives: To identify the dynamics of DHF incidence with spatio-temporal approach, includes gender, age, the habit of cleaning the water containers, house density, the density of water containers within the radius of 100 meters from the house of the patient, resistance of the mosquito, and transovarial transmission of Dengue virus.Methods: Subjects were DHF patients in Maritengngae Subdistrict. It was an epidemiological observational study with cross-sectional design and spatio-temporal approach to variables of the study, which included the patient characteristics (age, gender, habit of cleaning the water containers), environmental conditions (house density, water container density within 100 meter radius around the patient’s house), and vector conditions (resistance status to organophosphate insecticide, and transovarial transmission of Dengue virus).Results: Cases of DHF in Maritenggae Sub district, Sidenreng Rappang District, South Sulawesi decreased from 95 cases in 2008 to 38 cases in 2009, except in Kelurahan Majeling. Incidence distribution of DHF in 2008-2009 based on gender were not different (p=1.000), patients with age <15 years old were different from age ≥15 years (P=0.016 and p = 0.013), house density and density of water containers around the patient’s house were not different (p=0.829 and p = 0.538). The habit of cleaning water containers at the house was 43.84%. There were 1.94% of Aedes aegypti samples showed medium resistance (tolerance) status against organophosphat insecticide and 33.33% of samples showed transovarial transmission of Dengue virus. The highest of transovarial transmission occured in Kelurahan Majeling with transovarial transmission index of 100%.Conclusion: The transmission dynamic of DHF in Maritengngae sub district is not influenced by gender, house densities, water container densities, and the frequency of source reduction, but influenced by ages. Most of Ae. aegypti mosquitoes are still susceptible against organophosphate insecticides. The highest of transovarial transmission of dengue virus in Ae. aegypti in Kelurahan Majeling with Transovarial transmission index of 100% may contribute in the increasing of DHF cases in the Kelurahan Majeling in 2009.Keywords: dynamics, dengue, spatio-temporal, Ae. aegypti, Maritengngae.
Transovarial Transmission Index of Dengue Virus on Aedes aegypti and Aedes albopictus Mosquitoes in Malalayang District in Manado, North Sulawesi, Indonesia Angle Maria Hesti Sorisi; Sitti Rahmah Umniyati; Tri Baskoro Tunggul Satoto
Tropical Medicine Journal Vol 1, No 2 (2011): Tropical Medicine Journal
Publisher : Pusat Kedokteran Tropis

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1415.333 KB) | DOI: 10.22146/tmj.4571

Abstract

Introduction: Dengue Hemorrhagic Fever (DHF) is an infectious vector-borne disease caused by Aedes sp mosquitoes still cause serious health problem in Indonesia. Based on Manado Health Office Report, Malalayang was identified as dengue-endemic areas. In 2010, number of DHF cases in Malalayang is 211 cases with Incidence Rate (IR) 328 per 100,000 populations. Dengue viruses (DENV) survive in nature by two mechanisms; by horizontal transmission through infected vertebrates and mosquitoes, and by vertical (transovarial) transmission in the mosquitoes. Transovarial transmission is assumed as an important aspect in the maintanance of DENV during inter epidemic, but this problem has not been studied in Malalayang District, Manado. An effort to prevent and control DHF requires knowledge of an Aedes sp Dengue virus transovarial infection.Objectives: To prove the existence of Dengue virus transmission in Ae. aegypti and Ae. albopictus mosquitoes and its relationship with the incidence of DHF in Malalayang District in Manado, North Sulawesi, Indonesia.Methods: The method of this research was an observational analytic study with cross-sectional design. Study samples were unbloodfed Aedes aegypti and Aedes albopictus mosquitoes on the F1 generation from ovitrap placed in five selected villages based on the number of cases in the District Malalayang. The secondary data of DHF patients from Malalayang district was obtained from Health Office Manado and the Community Health Center in 2010. The presence of dengue antigen in head squashes preparation were detected using monoclonal antibody against dengue (DSSE10) based on immunohistochemical streptavidin biotin peroxidase complex (ISBPC) technique to confirm the presence of transovarial transmission of dengue virus both in Ae. Aegypti and Ae. Albopictus, and to obtain the data of transovarial transmission index. Fisher’s Exact test and Pearson correlation are used to analyze those data.Results: Transovarial transmission of Dengue virus in Aedes sp was found from 5 villages in Malalayang district with Transovarial Transmission Index (TTI) ranges 6.1%-17.1%. Statistic test showed significant differences in positive rate (p-value=0.00<0.05) on Ae. aegypti higher than Ae. albopictus. It is also known that there is no statistically significant correlation (p-value=0.528>0.05) between the Aedes sp. Dengue virus TTI and DHF IR in Malalayang district.Conclusion: This study demonstrates the existence of Dengue virus transovarial transmission in Aedes sp in Malalayang district. Ae. aegypti’s TTI is higher than that of Ae. Albopictus, and no significant correlation between TTI and DHF IR in Malalayang district.Keywords: DHF, transovarial transmission, Ae. aegypti, Ae. albopictus
A Study of Aedes aegypty Susceptibility Against Cypermetrin at Elementary Schools Yogyakarta Anies Mulyani; Damar Tri Boewono; Tri Baskoro Tunggul Satoto
Tropical Medicine Journal Vol 4, No 1 (2017): Tropical Medicine Journal
Publisher : Pusat Kedokteran Tropis

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (339.521 KB) | DOI: 10.22146/tmj.37177

Abstract

Introduction: Dengue Hemorrhagic Fever is transmitted by Aedes aegypti mosquitoes. Yogyakarta is an endemic area of DHF. One of the efforts of eradicating DHF in Yogyakarta was fogging with cypermethrin insecticide. Cypermethrin had been used since 2008 with a frequency of 1.469 times. However, repeated and prolonged application of chemical insecticide in an ecosystem unity may lead to vector resistance against the particular insecticide. Monitoring and early detection for the vector susceptibility status against insecticide was necessary in potential locations of DHF transmission, such as in elementary school. Detection of vector susceptibility status against insecticide could be conducted with susceptibility test using 0.05% cypermethrin impregnated paper.Objectives: To find out the status of Aedes aegypti susceptibility against cypermethrin insecticide and the relationship between the status of Aedes aegypti susceptibility with the frequency of cypermethrin application.Methods: An analytical observational research was conducted using cross-sectional design. Female Aedes aegypti from mosquito eggs collected at 72 state Elementary Schools in 45 villages in Yogyakarta were evaluated. Detection of Aedes aegypti susceptibility against cypermethrin was conducted using WHO standard method, namely, susceptibility test, which used 0.05% cypermethrin impregnated paper.Results: Aedes aegypti at elementary schools in Yogyakarta had been resistant against 0.05% cypermethrin, with an average mortality of 4.03%. No correlation between Aedes aegypti susceptibility in the elementary schools in Yogyakarta and the frequency of cypermethrin application. This might be attributable to the use of household insecticide and to the resistance history of the test animals.Conclusions: The population of Aedes aegyptiat the State Elementary Schools in Yogyakarta was found to be resistant against 0.05% cypermethrin. No relationship between Aedes aegypti susceptibility status and the frequency of cypermethrin application. Keywords: Aedes aegypti, Cypermethrin, impregnated paper, Susceptibility Test,  INTISARI Pendahuluan: Demam Berdarah Dengue adalah penyakit infeksi yang disebarkan oleh nyamuk Aedes aegypti. Kota Yogyakarta merupakan daerah endemis DBD. Salah satu cara penanggulangan DBD di kota Yogyakarta dengan pengasapan menggunakan insektisida sipermetrin. Penggunaan sipermetrin sudah dilakukan sejak tahun 2008 dengan frekuensi aplikasi sebanyak 1469 kali. Aplikasi insektisida kimia dalam waktu lama dan berulang di satuan ekosistem dapat menimbulkan resistensi vector terhadap insektisida yang digunakan.  Monitoring dan deteksi dini status kerentanan vector terhadap insektisida di kota Yogyakarta perlu dilakukan di lokasi yang berpotensi sebagai tempat penularan DBD diantaranya di sekolah dasar. Deteksi status kerentanan vector terhadap insektisida dapat dilakukan dengan susceptibility test menggunakan impregnated paper sipermetrin 0.05%.Tujuan: Mengetahui status kerentanan nyamuk Aedes aegypti di Lingkungan SDN di Kota Yogyakarta terhadap insektisida sipermetrin dan mengetahui hubungan status kerentanannya dengan frekuensi aplikasi insektisida sipermetrin.Metode: Penelitian ini merupakan penelitian observasional analitik dengan rancangan crosssectional. Subyek penelitian populasi nyamuk Aedes aegypti dari telur yang berasal dari 72 SDN di 45 kelurahan di Kota Yogyakarta. Deteksi status kerentanan nyamuk Aedes aegypti terhadap insektisida sipermetrin dilakukan dengan metode standar WHO susceptibility test menggunakan impregnated paper sipermetrin 0.05%.Hasil: Hasil uji kerentanan menunjukkan nyamuk Aedes aegypti di lingkungan sekolah dasar di kota Yogyakarta sudah resisten terhadap insektisida sipermetrin 0.05% dengan angka kematian nyamuk rata-rata 4.03%. Tidak ada korelasi antara status kerentanan nyamuk Aedes aegypti dengan frekuensi aplikasi insektisida sipermetrin. Hal ini bisa disebabkan karena penggunaan insektisida rumah tangga yang digunakan oleh masyarakat dan karena adanya riwayat resistensi dari nyamuk uji.Simpulan: Populasi nyamuk Aedes aegypti di lingkungan Sekolah Dasar Negeri di Kota Yogyakarta sudah resisten terhadap insektisida Sipermetrin 0.05%. Tidak ada hubungan status kerentanan nyamuk Aedes aegypti di lingkungan sekolah dasar negeri di Kota Yogyakarta dengan frekuensi aplikasi insektisida sipermetrin. Kata kunci: Aedes aegypti, Insektisida Sipermetrin, impregnated paper, Uji kerentanan, Sekolah Dasar
Co-Authors Achmad Fudholi Ajib Diptyanusa Ajib Diptyanusa Ajib Diptyanusa Alamri, Annisa Rizqa Ali Wardana Ali Wardana Alvin Harjono Dwiputro Alvira Pascawati, Nur Angle Maria Hesti Sorisi Anies Mulyani Anis Fuad Anwar Dwi Cahyono Ardhi, Khairil Ariyanto Nugroho Barandi Sapta Widartono Barandi Sapta Widartono Budi Mulyaningsih Budi Mulyaningsih Budi Mulyaningsih Budi Mulyaningsih Damar Tri Boewono Diptyanusa, Ajib Diptyanusa, Ajib Dwi Aris Agung Nugrahaningsih Dwi Sarwani Sri Rejeki Dwiputro, Alfin Harjuno Dyah Mahendrasari Sukendra E. Elsa Herdiana Murhandarwati Edhi Martono Elisabeth Deta Lustiyati Ellen Petra Songjanan Ellen Petra Songjanan Ernaningsih Ernaningsih Ernaningsih Ernaningsih Frutos, Roger Fudholi, Achmad - Hakim, A. Ulil Fadli Hanani Melangwala Laumalay Hardaningsih, Ignatius Hari Kusnanto Hastuti Tongkodu I Kadek I Kadek Mulyawan I Made Swastika Ikhwan Mustiadi Insani, Dini Aura Joy Victor Imanuel Sambuaga Kurnia, Risman Kusumasari, Rizqiani Amalia Kuswati Kuswati Laksono, Rian Kurniawan Lilik Zuhriyah Lusiana Utari, Evrita Lutfan Lazuardi Lutfan Lazuardi Luthfan Lazuardi M Lutfan Lazuardi Mae Sri Hartati Wahyuningsih Maguin, Sylvie Mahardika Agus Wijayanti Mbiliyora, Agustina Mubarak Mubarak muhaimin saranani Mujiyanto Mujiyanto Mujiyanto Mujiyanto Mulyawan, I Kadek Najla, Aesha Pangesti, Rachma Widya Pascawati, Nur Alvira Perdana, Taufik Mulya Purwono Purwono R. Suharyadi Risdwiyanto, Rifa Nadhifa Ristiyanto Roger Frutos Roger Frutos Roger Frutos Ruben Wadu Wila Satrisno, Hary Setiawan, Yohanes Didik Siti Istianah Sitti Rahmah Umniyati Sitti Rahmah Umniyati Sitti Rahmah Umniyati Sitti Rahmah Umniyati Sitti Rahmah Umniyati Sitti Rahmah Umniyati Slamet Riyadi Suhermanto - Sulistyawati Sulistyawati Supriyati Sylvie Maguin Sylvie Maguin Sylvie Maguin Taftazani, Muhammad Rifqi Tri Murini Tri Murini Tri Wahono Tri Wahyuni Sukesi Tri Wibawa Tri Wibawa Tri Wibawa Tri Wibawa Tridjoko Hadianto, Tridjoko Trisno Agung Wibowo Triwibowo Ambar Garjito Triwibowo Ambar Garjito Unida, Tazkiah Wardana, Ali Wulandari, Indah Sari Yahiddin Selian Yogik Onky Silvana Wijaya