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PENYULUHAN PENYIMPANAN OBAT DI RT 009 RW 004 DESA SANGIANG KECAMATAN PAMARAYAN KABUPATEN SERANG Sefi Megawati; Meta Safitri; Dania Maretiana; Elsa Agustyani Sukma Soleha; Ervina Damayanti Oktavia; Fitria Novfrianti Musrizal
MONSU'ANI TANO Jurnal Pengabdian Masyarakat Vol. 8 No. 1 (2025)
Publisher : Universitas Muhammadiyah Luwuk

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32529/tano.v8i1.3483

Abstract

Menyimpan obat merupakan sesuatu hal yang penting untuk memastikan kualitas produk. Obat dapat menjadi tidak efektif atau bahkan rusak karena prosedur atau kondisi penyimpanan yang tidak sesuai, yang dapat merugikan pasien yang akan mengkonsumsi obat tersebut. Kegiatan ini memiliki tujuan yaitu meningkatkan kesadaran masyarakat desa Sangiang RT 009 RW 004 Kecamatan Pamarayan Kebupaten Serang tentang cara yang baik dan benar untuk menyimpan obat. Kegiatan ini terdapat tiga tahap, Tahap pertama yaitu pengenalan dan pengisian kuisioner pretest. Tahap kedua adalah pemaparan langsung mengenai cara penyimpanan obat menggunakan powerpoint dan workshop cara penyimpanan obat yang baik dan benar. Tahap ketiga adalah diskusi, tanya jawab, dan penutupan. Hasil menunjukkan tingkat pengetahuan Masyarkat Desa Sangiang RT 009 RW 004 sebelum penyuluhan baik 8,3%; cukup 28,3%; kurang 63,3% setelah penyuluhan baik 43,3%;cukup  40%; kurang 16,67%. Terjadi peningkatan pengetahuan masyarakat sesudah penyuluhan.
Test Of Antibacterial Activity and GC-MS analysis of ethyl acetate and N-hexane fractions of Kenitu leaves (Chrysophyllum cainito L.) Megawati, Sefi; Meta Safitri; Rangkuti, Saru Noliqo; Luthfiyyatul Makiyyah; Arum Mawarni, Nur Indah
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2421

Abstract

Background: As a result of the large number of infectious diseases, every year 3.5 million people die. The more microorganisms that are resistant to antibiotics, the search for and research into new antibacterials must be carried out from medicinal plant extracts such as the kenitu leaf plant, whose antibacterial activity is still rarely researched. Objectives: to analyze the factors that influence the management of solid media waste of hazardous and toxic materials at RSUD.Kumpulan Pane, Tebing Tinggi City. Research method: This research is a type of laboratory experiment using the semi-polar solvent ethyl acetate and the non-polar solvent n hexane from kenitu (Chrysophyllum cainito L.) leaves to test their antibacterial activity using the disk diffusion method. In this study there were six treatment groups: positive control (+) ciprofloxacin, negative control (-) DMSO 10%, as well as four concentration variations, namely K1: 25 mg/ml, K2: 50 mg/ml, K3: 100 mg/ml, and K4: 500 mg/ml. Results: The results of the ANOVA test of the antibacterial activity test of the Bacillus subtilis fraction against the ethyl acetate fraction obtained a p value <0.001. From the results of the homogeneity test, a significant value of p = 0.023 was obtained. These values ??are in accordance with the criteria (p <0.05), meaning that the concentration treatment has a significant impact on the diameter of the inhibition zone. Based on the results of the two tests, the data obtained in this study were analyzed using the non-parametric Kruskal-Wallis statistical test showing that there was a difference in the average Asymp value in each treatment. Sig. = 0.005 (p <0.05). The results of the Mann-Whitney test of the ethyl acetate fraction on Bacillus subtilis bacteria stated that it had a significant difference in providing an inhibition zone. Conclusion: the analysis stated that there were 27 compounds that were identified in the ethyl acetate fraction and 19 compounds that were identified in the n-hexane fraction of kenitu leaves. The results of testing regarding antibacterial activity stated that the kenitu leaf fraction from ethyl acetate solvent was only able to inhibit the growth of Bacillus subtilis and Staphylococcus aureus bacteria at a concentration of 500 mg/ml, for the kenitu leaf fraction from n-hexane solvent stated that all concentrations were not possible. able to inhibit the growth of Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Bacillus subtilis.
Antioxidant Activity Test And Permeability Test of Antioxidant Cream Preparation of 96% Ethanol Extract of Kaffir Lime Fruit Peel (Citrus hystrix) With The Addition of Enhancer Meta Safitri; Syifa Afiatun Nisa; Firdanu Nupus; Mohammad Zaky; Nuriyatul Fathonah
Pharmacon: Jurnal Farmasi Indonesia Volume 22, No 1 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i1.6880

Abstract

This study aimed to determine the antioxidant activity, levels contained in kaffir lime peel extract, and penetration test on the antioxidant cream preparation of kaffir lime peel extract. This research method is experimental with descriptive analysis and SPSS. This extract was obtained by maceration using 96% ethanol and then standardizing the specific and non-specific extracts. The dosage form made is a cream with an extract concentration of 15% and modified enhancer variations F0 (without enhancer), F1 (10% propylene glycol), F2 (10% oleic acid), and F3 (5% propylene glycol and 5% oleate). The cream preparation was tested for physical evaluation of the preparation, % inhibition antioxidant activity using the DPPH technique and permeability test activity using Franz diffusion. The results showed that there were hesperidin levels of 25.34 mg/g, naringin 1.94 mg/g. Physical evaluation tests show that the cream fulfill all appropriate physical requirements, including homogeneity and organoleptic, pH, viscosity, spread ability, stickiness, cream type. The antioxidant activity of vitamins based on the inhibition percentage value is greater when compared to antioxidant cream, namely 41.604. The SPSS test uses One Way Anova, and the permeability test results of the largest cumulative amount and flux value were found in F2 with values ​​respectively 341.983 µg/cm2, 0.928 µg/cm2/minute. It can be concluded that the cream preparation made has antioxidant activity and permeability with the addition of 10% oleic acid enhancer which can influence penetration into the skin.
Pengenalan Jenis Makanan Sehat terhadap Anak Usia Dini melalui Media Audio Visual di Kecamatan Pasar Kemis, Kabupaten Tangerang Sylvia, Diana; Utami, Fitria Budi; Rusdiana, Nita; Daulay, Meilyn A.K.; Ari, Muhamad Ilham; Sujera, Lulu; Megawati, Sefi; Safitri, Meta
Jurnal ABDIRAJA Vol 8 No 2 (2025): Jurnal Abdiraja
Publisher : LPPM Universitas Wiraraja Sumenep, Jalan Raya Sumenep Pamekasan KM. 5 Patean Sumenep 69451, Telp. (0328) 673399 Fax. (0328) 673088

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24929/adr.v8i2.4324

Abstract

Masa kanak-kanak merupakan periode krusial dalam pembentukan kebiasaan makan yang dapat memengaruhi kesehatan jangka panjang. Namun, banyak anak usia dini yang belum memahami pentingnya dalam mengkonsumsi makanan sehat, yang dapat mengakibatkan kurangnya edukasi gizi yang sesuai dengan tahapan perkembangan mereka. Pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pemahaman anak usia dini mengenai jenis makanan sehat melalui pendekatan edukatif berbasis media audio visual. Kegiatan ini dilaksanakan di lembaga PAUD di Kecamatan Pasar Kemis, Kabupaten Tangerang, dengan melibatkan para murid sebagai objek, dan para guru sebagai pendukung utama pada proses pembelajaran. Metode yang digunakan meliputi pemutaran video interaktif, diskusi sederhana, dan aktivitas edukasi tentang makanan sehat. Hasil kegiatan menunjukkan peningkatan antusiasme dan pemahaman anak-anak terhadap makanan sehat, serta respon positif dari para murid dan guru terhadap metode pembelajaran yang digunakan. Diharapkan program ini dapat menjadi model edukasi gizi yang menyenangkan dan efektif untuk diterapkan secara luas di tingkat PAUD.
INNOVATION OF CORN SHEET (ZEA MAYS.L) AND AVOCADO SEEDS (PERSEA AMERICANA MILL) BISCUIT BASED ON ALTERNATIVE FOODS TO PREVENT STUNTING IN TODDLERS Radooti Merlin Sagala; Saru Noliqo Rangkuti; Sefi Megawati; Azzahra Fernanda; Meta Safitri; Arini Aprilliani
International Journal of Social Science, Educational, Economics, Agriculture Research and Technology (IJSET) Vol. 4 No. 7 (2025): JUNE
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ijset.v4i7.1015

Abstract

Stunting remains a critical issue in Indonesia due to chronic nutritional deficiencies. This study developed functional biscuits using corn silk and avocado seed flours in three ratios (25:75, 50:50, 75:25) to support toddler nutrition. Nutritional and sensory evaluations showed that the 50:50 formulation was optimal, containing 5.34% protein, 23.98% fat, and 68.01% carbohydrates. Although slightly below the SNI carbohydrate standard (≥70%), it met moisture and ash standards and was preferred in taste, color, and aroma. These findings highlight its potential as a supplementary food to help prevent stunting in early childhood.