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FAKTOR KORELASI KEJADIAN MIKROALBUMINURIA PADA PENDERITA DIABETES MELITUS TIPE 2 DI KLINIK PRATAMA KIMIA FARMA MAKASSAR Syahida Djasang; Artati Artati; Budirman Budirman; Kalma Kalma; Zulfikar Ali Hasan
Jurnal Media Analis Kesehatan Vol 14, No 1 (2023): JURNAL MEDIA ANALIS KESEHATAN
Publisher : Poltekkes Kemenkes Pakassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/mak.v14i1.3247

Abstract

Diabetes Mellitus merupakan penyakit metabolik akut dengan tingginya kadar glukosa darah. DM ini juga menghasilkan beberapa komplikasi penyakit seperti nefropati diabetes ditandai dengan albuminuria persisten dan disertai berbagai faktor risiko. Tujuan penelitian ini adalah untuk mengetahui faktor korelasi dengan kejadian mikroalbuminuria pada penderita DM tipe 2. Penelitian ini merupakan penelitian uji korelasi dengan sampel sebanyak 50 orang menggunakan tehnik purposive sampling. Penelitian ini dilaksanakan di Laboratorium Klinik Kimia Farma Makassar pada tanggal 25 Maret – 20 April 2022. Pengumpulan data yakni karakteristik responden dan pengambilan sampel urine untuk mendiagnosis kadar albumin pasien. Analisis data menggunakan pendekatan bivariat dengan uji statistik Korelasi Pearson. Hasil penelitian menunjukkan sebagian besar sampel memiliki kadar mikroalbumin >20 mg/L sebesar 86%, berusia >45 tahun sebesar 86%, mengkonsumsi obat >3 tahun sebesar 70%, memiliki lama diabetes >3 tahun sebesar 74%, dan mengonsumsi jenis obat dosis tinggi sebesar 84%. Kemudian, hasil bivariat menunjukkan terdapat hubungan faktor usia, lama minum obat, lama diabetes, dan jenis obat dengan kejadian Mikroalbumin pada pasien DM tipe 2 dengan masing-masing nilai p value 0,017, 0,000, 0,003 dan 0,037 (p<0,05). Diharapkan kepada masyarakat untuk senantiasa menerapkan pola hidup sehat agar kualitas kehidupan semakin terjamin kedepannya dan diharapkan hasil penelitian ini menjadi bahan rekomendasi dalam pengembangan penelitian selanjutnya.
Modification of the Calculation of the Examination of the Platelet Count Using 1 Large Box of Leukocytes in the Improved Neubauer Counting Room Zulfikar Ali Hasan; Nurdin Nurdin; Ridho Pratama; Artati Artati; Yaumil Fachni Tandjungbulu; Andi Fajrin Permana
Jurnal Media Analis Kesehatan Vol 14 No 2 (2023): JURNAL MEDIA ANALIS KESEHATAN
Publisher : Potekkes Kemenkes Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/jmak.v14i2.256

Abstract

The direct examination of the platelet count using the improved Neubauer counting chamber is carried out by microscopic examination of 25 Medium Boxes of Erythrocytes, this method requires several field shifts so that more accuracy is needed when carrying out the examination. Modification of the calculation of the platelet count by using 1 large box of leukocytes in the improved Neubauer counting chamber requires only 1 field of view at the time of calculation so that it does not take a long time and is more thorough when carrying out microscopic platelet counts. The purpose of this study was to determine the number of platelets using the calculation of 25 squares while the erythrocytes and the number of platelets using a modification of the calculation of 1 large box of leukocytes. This type of research is a quasi-experimental which aims to determine the effect that arises due to certain treatments for examining the platelet count using 25 boxes while the erythrocytes and modification of the calculation using 1 large box of leukocytes. It was carried out at the Hematology Laboratory, Department of Medical Laboratory Technology, Poltekkes Kemenkes Makassar. This research was carried out to start in January-December 2022. Examination of the number of platelets in the counting chamber with 25 Medium Boxes of Erythrocytes and 1 Large Box of Leukocytes, from the 30 data obtained for each method after a different test using the Mann Whitney test obtained a significant p value of 0.234 > 0.05 so that it can be concluded that there is no difference in the number of platelets in 25 Medium Boxes of Erythrocytes and 1 Large Box of Leukocytes. This indicates that examination of the platelet count using 1 large box of leukocytes can be used as a manual examination method
Identifikasi Jamur Penyebab Onychomycosis Pada Kerokan Kuku Pekerja Bangunan Di Desa Bontokassi Kecamatan Parangloe Kabupaten Gowa Zulfikar Ali Hasan; Radiatul Adawiyah; Nurlia Naim; Zulfian Armah
Lontara Journal of Health Science and Technology Vol 3 No 1 (2022): Ilmu dan Teknologi Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v3i1.272

Abstract

Onychomycosis is a disease caused by dermatophyte and non-dermatophyte fungi that can attack human nails. Work environment, personal hygiene of workers, age and length of work can increase the risk of Onychomycosis. This study aims to identify the fungi that cause Onychomycosis on the nails of construction workers. This research is descriptive observational and using purposive sampling technique. This study used 2 methods of examination, namely directly and indirectly using 20% KOH and planting on Sabouraud Dextrose Agar culture media. The results of the identification of 15 samples using 20% KOH, found 1 (6.67%) positive sample with the discovery of hyphae and spores while 14 (93.3%) other samples were negative. The results of the identification on Sabouraud Dextrose Agar media that had been incubated at 37 oC for 3-5 days, it was found that 15 (100%) samples were positive for fungal infection. The Non-Dermatophyte, namely the discovery of 6 samples (40%) of Aspergillus Sp fungi and 5 samples of Penicillium Sp fungi (33.33%) and the discovery of Dermatophyte fungi, namely Trichopyton sp fungi as many as 3 samples (20%) and Epidermophyton sp as much as 1 sample (6.67%).
Perbandingan Kualitas Trombocyte Concentrate Dari Platelet Rich Plasma Dan Platelet Apheresis Pada Jumlah Trombosit Dan Residu Leukosit Rafika, Rafika; Amelia, Dewicha; Naim, Nurlia; Hasan, Zulfikar Ali
Jurnal Analis Kesehatan Vol. 10 No. 1 (2021): JURNAL ANALIS KESEHATAN
Publisher : Department of Health Analyst, Politeknik Kesehatan, Kementerian Kesehatan Tanjungkarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jak.v10i1.2717

Abstract

Transfusi trombosit sebagai terapi utama bagi pasien dengan trombositopenia. Pasien dewasa, sekitar 6 unit TC-PRP dibutuhkan dosis tersebut setara dengan 1 unit platelet apheresis. Semakin banyak TC-PRP yang ditransfusikan maka akan semakin tinggi paparan residu leukosit yang diterima. Penelitian ini mengetahui perbandingan kualitas TC-PRP dan platelet apheresis dilihat dari jumlah trombosit dan residu leukosit. Jenis penelitian analitik observasional laboratorik di Instalasi Laboratorium Sentral RSUP Dr. Mohammad Hoesin Palembang. Sampel ditentukan secara purposive sampling sebanyak 40 sampel pada 2 subyek yang berbeda. Pada TC-PRP, sebesar 15% unit memiliki jumlah trombosit ≥60x10⁹ dengan nilai rata-rata 617x103/µL dan 100% unit memiliki residu leukosit ≤0,2x10⁹ dengan nilai rata-rata 0,223x103/µL. Pada platelet apheresis, sebesar 100% unit memiliki jumlah trombosit ≥2,0x10¹¹ dengan nilai rata-rata 859x103/µL dan residu leukosit ≤0,3x10⁹ dengan nilai rata-rata 0,009x103/µL. Berdasarkan Permenkes RI No.91/2015, jumlah trombosit pada TC-PRP tidak memenuhi persentase standar sedangkan residu leukosit memenuhi standar yang direkomendasikan. Pada platelet apheresis, kedua parameter memenuhi standar yang direkomendasikan. Secara statistik diperoleh nilai p = 0,003 bahwa ada perbedaan pada jumlah trombosit antara TC-PRP dan platelet apheresis, serta diperoleh nilai p = 0,000 berarti ada perbedaan yang pada jumlah residu leukosit antara TC-PRP dan platelet apheresis. Platelet apheresis memiliki kualitas lebih baik daripada TC-PRP
Aktivitas Antioksidan Dari Tiga Fraksi Pelarut Ekstrak Daun Dandang Gendis (EDDG) Artati, Artati; Widarti, Widarti; Ali Hasan, Zulfikar; Askar, M
Jurnal Media Analis Kesehatan Vol 15 No 2 (2024): JURNAL MEDIA ANALIS KESEHATAN
Publisher : Potekkes Kemenkes Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/jmak.v15i2.1159

Abstract

Ekstrak daun Dandang Gendis (EDDG) memiliki potensi sebagai agen antioksidan dan antimikroba yang dapat digunakan dalam pengobatan tradisional dan modern. Penelitian ini bertujuan untuk mengeksplorasi manfaat kesehatan dari ekstrak daun ekstrak daun dandang gendis (Clinacanthus nutans L.) serta biokomponen aktif yang terkandung di dalamnya. Jenis penelitian ini merupakan penelitian eksperimental dengan pendekatan kuantitatif yang melibatkan analisis laboratorium. Sampel yang digunakan dalam penelitian ini adalah daun ekstrak daun dandang gendis (Clinacanthus nutans L.) dengan berbagai pelarut, yaitu n-heksan, etil asetat dan etanol. Uji aktivitas antioksidan dilakukan dengan menggunakan metode spektrofotometri UV-Vis menggunakan beberapa pereaksi yang berfungsi sebagai antioksidan diantaranya 2,2-diphenyl-1- picrylhydrazyl (DPPH) dan besarnya aktivitas antioksidan ditandai dengan nilai IC50. Aktivitas antioksidan terhadap radikal DPPH dianalisis menggunakan spektrofotometer visibel pada panjang gelombang 517 nm. Kemampuan aktivitas antioksidan ekstrak dibandingkan dengan asam askorbat. Aktivitas antioksidan (IC50) berdasarkan tiga jenis pelarut yang digunakan untuk mengekstrak yaitu n-heksan, etil asetat, dan etanol masing-masing adalah 1658 µg/ml, 160 µg/ml, dan 2471 µg/ml. Hasil penelitian menunjukkan bahwa ekstrak daun EDDG memiliki aktivitas antioksidan yang signifikan dan dapat menghambat pertumbuhan bakteri patogen. Disarankan untuk melakukan penelitian lebih lanjut mengenai isolasi komponen bioaktif dan uji klinis untuk memancarkan potensi terapeutik dari ekstrak ini.
Bahasa Inggris Ronny, Ronny; Hasan, Zulfikar Ali; Telan, Albina Bare
Jurnal Kesehatan Manarang Vol 10 No 3 (2024): December 2024
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v10i3.1781

Abstract

Efforts to meet clean water needs, especially for drinking water, depend on the condition of groundwater that is healthy and sufficiently available. Filtration is the process of separating particles from a liquid by passing the liquid through a permeable material. This study examines the Gravity-Fed Filtering System with innovative Imhoff technology, combined with a Primary Treatment stage, to produce clearer and higher-quality water. The objective of this research is to assess the effectiveness of this system in reducing contamination levels in groundwater, including iron (Fe), manganese (Mn), total hardness (Ca and Mg), and organic compounds. The study employed an experimental method with a quantitative approach and used a One Group Pretest-Posttest design. The research was conducted in two locations: Barombong Village in Makassar and Pauwo Village in Gorontalo. Fifteen samples were randomly selected for analysis. The study began with preliminary observations and initial testing in March 2022, followed by the main research and prototype evaluation in 2023-2024. The results show that the system effectively reduced Fe, Mn, organic compounds, and total hardness levels. In Makassar, the highest reduction in Fe is 87.3% in sample 8, while in Gorontalo, the highest reduction is 93.3% in sample 8. The highest reduction in manganese (Mn) in Makassar is 63.3% in sample 1, and in Gorontalo, it is 62.1% in sample 1. The highest reduction in organic compounds in Makassar is 81.6% in sample 3, while the lowest reduction in total hardness in Makassar is 77.1% in samples 4, 5, 6, and 10. In Gorontalo, the highest reduction in total hardness is 90.3% in samples 1, 2, and 3. Recommendations for the community, The use of gravity-fed filtering system technology as one of the media used to reduce iron and manganese concentrations is considered quite good, but for similar research to be carried out, modifications should be made to the media specifically starting with the size, shape and other variables that support it so that it is more effective in reducing pollutant concentrations.
Identifikasi Jamur Penyebab Onychomycosis Pada Kerokan Kuku Pekerja Bangunan Di Desa Bontokassi Kecamatan Parangloe Kabupaten Gowa Hasan, Zulfikar Ali; Adawiyah, Radiatul; Naim, Nurlia; Armah, Zulfian
Lontara Journal of Health Science and Technology Vol. 3 No. 1 (2022): Ilmu dan Teknologi Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v3i1.272

Abstract

Onychomycosis is a disease caused by dermatophyte and non-dermatophyte fungi that can attack human nails. Work environment, personal hygiene of workers, age and length of work can increase the risk of Onychomycosis. This study aims to identify the fungi that cause Onychomycosis on the nails of construction workers. This research is descriptive observational and using purposive sampling technique. This study used 2 methods of examination, namely directly and indirectly using 20% KOH and planting on Sabouraud Dextrose Agar culture media. The results of the identification of 15 samples using 20% KOH, found 1 (6.67%) positive sample with the discovery of hyphae and spores while 14 (93.3%) other samples were negative. The results of the identification on Sabouraud Dextrose Agar media that had been incubated at 37 oC for 3-5 days, it was found that 15 (100%) samples were positive for fungal infection. The Non-Dermatophyte, namely the discovery of 6 samples (40%) of Aspergillus Sp fungi and 5 samples of Penicillium Sp fungi (33.33%) and the discovery of Dermatophyte fungi, namely Trichopyton sp fungi as many as 3 samples (20%) and Epidermophyton sp as much as 1 sample (6.67%).
Analysis of Risk Factors for Tuberculosis Incidence in the Awaru Awangpone Public Health Center Working Area, Bone: An Analytical Observational Study Ronny; Zulfikar Ali Hasan; Jasman; RH Kristina; Albina Bare
Gema Lingkungan Kesehatan Vol. 23 No. 2 (2025): Gema Lingkungan Kesehatan
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v23i2.223

Abstract

Tuberculosis (TB) remains a global health challenge, particularly in regions with inadequate environmental conditions. This study aims to analyze the association between lighting, humidity, ventilation area, and residential density with TB incidence in the working area of Awaru Awangpone Public Health Center, Bone Regency. This analytical observational study used a cross-sectional design. Data were collected through direct observation and interviews, and statistical analysis was conducted using the Chi-Square test with a 95% confidence level (α = 0.05). The relationship between risk factors and TB incidence was measured using the Odds Ratio (OR) and 95% Confidence Interval (CI). The result show inadequate lighting was significantly associated with TB incidence (p = 0.032, OR = 1.10, 95% CI: 0.55–2.22). Ventilation area also showed a significant relationship with TB incidence (p = 0.031, OR = 5.25, 95% CI: 1.17–26.02). However, no significant association was found between humidity and TB incidence (p = 0.946, OR = 0.97, 95% CI: 0.45–2.11). Residential density was significantly related to TB incidence (p = 0.038, OR = 0.44, 95% CI: 0.76–3.08). Environmental factors, particularly lighting, ventilation, and residential density, play a crucial role in TB transmission.  These findings highlight the need for targeted interventions to improve living environments in high risk areas.
Optimalisasi Ubi Jalar Putih (Ipomoea Batatas L.) Sebagai Media Alternatif Pengganti PDA untuk Pertumbuhan Aspergillus flavus Pratama, Ridho; Khatimah, Husnul; Adam, Alfira; Rafika, Rafika; Armah, Zulfian; Artati, Artati; Hasan, Zulfikar Ali
Jurnal Media Analis Kesehatan Vol 16 No 1 (2025): JURNAL MEDIA ANALIS KESEHATAN
Publisher : Potekkes Kemenkes Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/jmak.v16i1.1434

Abstract

Jamur Aspergillus flavus merupakan salah satu jenis kapang yang memiliki peran penting dalam berbagai bidang, termasuk industri pangan dan kesehatan. Media pertumbuhan jamur secara umum menggunakan Potato Dextrose Agar (PDA), namun biaya dan ketersediaan media ini dapat menjadi kendala dalam penelitian skala besar. Penelitian ini bertujuan untuk mengevaluasi efektivitas ubi jalar putih sebagai media alternatif untuk pertumbuhan Aspergillus flavus dibandingkan dengan media PDA komersial. Hasil penelitian menunjukkan bahwa Aspergillus flavus dapat tumbuh secara optimal pada media alternatif berbasis ubi jalar putih dengan karakteristik pertumbuhan yang serupa dengan media PDA. Faktor-faktor seperti kandungan karbohidrat, pH, suhu, dan kelembaban berperan penting dalam mendukung pertumbuhan jamur. Tidak ditemukan perbedaan yang signifikan antara media PDA dan media alternatif dalam mendukung pertumbuhan Aspergillus flavus. Kesimpulan dari penelitian ini adalah ubi jalar putih memiliki potensi sebagai media alternatif yang efektif untuk pertumbuhan Aspergillus flavus, terutama dalam kondisi penelitian yang memerlukan bahan yang lebih ekonomis dan mudah diperoleh.
Innovative Gravity-Fed Filtration System to Improve Coastal Community Water Quality Ronny, Ronny; Hasan, Zulfikar Ali; Telan, Albina Bare
Jurnal Kesehatan Manarang Vol 10 No 3 (2024): Bahasa Inggris
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v10i3.1781

Abstract

Efforts to meet clean water needs, especially for drinking water, depend on the condition of groundwater that is healthy and sufficiently available. Filtration is the process of separating particles from a liquid by passing the liquid through a permeable material. This study examines the Gravity-Fed Filtering System with innovative Imhoff technology, combined with a Primary Treatment stage, to produce clearer and higher-quality water. The objective of this research is to assess the effectiveness of this system in reducing contamination levels in groundwater, including iron (Fe), manganese (Mn), total hardness (Ca and Mg), and organic compounds. The study employed an experimental method with a quantitative approach and used a One Group Pretest-Posttest design. The research was conducted in two locations: Barombong Village in Makassar and Pauwo Village in Gorontalo. Fifteen samples were randomly selected for analysis. The study began with preliminary observations and initial testing in March 2022, followed by the main research and prototype evaluation in 2023-2024. The results show that the system effectively reduced Fe, Mn, organic compounds, and total hardness levels. In Makassar, the highest reduction in Fe is 87.3% in sample 8, while in Gorontalo, the highest reduction is 93.3% in sample 8. The highest reduction in manganese (Mn) in Makassar is 63.3% in sample 1, and in Gorontalo, it is 62.1% in sample 1. The highest reduction in organic compounds in Makassar is 81.6% in sample 3, while the lowest reduction in total hardness in Makassar is 77.1% in samples 4, 5, 6, and 10. In Gorontalo, the highest reduction in total hardness is 90.3% in samples 1, 2, and 3. Recommendations for the community, The use of gravity-fed filtering system technology as one of the media used to reduce iron and manganese concentrations is considered quite good, but for similar research to be carried out, modifications should be made to the media specifically starting with the size, shape and other variables that support it so that it is more effective in reducing pollutant concentrations.