Article Per Year (5 Year)
p-Index From 2020 - 2025
2.338
P-Index
This Author published in this journals
All Journal BALI MEDICAL JOURNAL (BMJ) journal of internal medicine INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES E-Jurnal Medika Udayana Jurnal Teknik ITS IPTEK Journal of Proceedings Series Medical Journal of Indonesia R.E.M (Rekyasa Energi Manufaktur) Jurnal The Indonesian Biomedical Journal Jurnal Administrasi Pendidikan Indonesia Jurnal Penyakit Dalam Udayana Jurnal Kelautan Nasional Wave: Jurnal Ilmiah Teknologi Maritim ISM (Intisari Sains Medis) : Jurnal Kedokteran International Journal of Marine Engineering Innovation and Research GANESHA MEDICINA Public Health and Preventive Medicine Archive Makara Journal of Technology Jurnal Penyakit Dalam Indonesia
I Ketut Suastika
Institut Teknologi Sepuluh Nopember Surabaya
Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Physics Public Health Transportation

Published : 53 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Jurnal Penyakit Dalam Indonesia

 1 
Low Serum Irisin as A Risk Factor of Sarcopenia in Elderly Aryana, I Gust Putu Suka; Putrawan, I.B.; Purnami, Ni Ketut Rai; Kuswardhani, R.A. Tuty; Astika, I Nyoman; Suastika, Ketut; Adiatmika, I Putu Gede; Jawi, I Made; Wande, I Nyoman
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 4
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction. Sarcopenia is a condition characterized by a decrease in muscle mass accompanied by a decrease in strength and/or function. Sarcopenia is closely related to the aging process, but the mechanism of its occurrence is still not fully understood. Skeletal muscle is the largest organ in the human body, so the myokine produced through muscle contraction opens a new paradigm regarding the central role of muscles in regulating metabolism and other organ functions. One of the myokines that are currently found to affect physical activity is Irisin. This study aims to determine the role of low Irisin levels in serum as a risk factor for sarcopenia in the elderly. Methods. This case-control study was conducted in Denpasar City from January 2020 to October 2020. The sample was selected using purposive consecutive sampling with matching age and gender, with 54 subjects, 27 case groups, and 27 control groups aged ≥60 years. Sarcopenia status is enforced by the criteria of the Asian Working Group for Sarcopenia (AWGS). Irisin serum levels were measured by enzyme-linked immunosorbent assay (ELISA). Results. Based on 54 subjects, the mean age in cases was 69.79 (SD 5.00) years and controls 67.89 (SD 4.50) years (p = 0.152), the proportion of male:female both in cases and controls group was 9:18. The cut-off point value wass based on the irisin ROC curve 4.51 ng/L. Nutritional status (OR = 3.40 (95% CI = 1.11 - 10.40); p = 0.029) and irisin (OR = 25.30 (95% CI = 6,00 - 106.66); p = <0.001) had an effect on sarcopenia. Factors that purely influence sarcopenia were found in low irisin (OR = 103.41 (95% CI = 7.83 – 1,364.99; p = <0.001). Conclusions. Low Irisin level is a risk factor for sarcopenia in the elderly. Irisin could be considered for further investigation in an effort to become a target for both preventive and curative therapy for sarcopenia.
Co-Authors A Santoso A. A. Mas-Putrawati AAG Budhiarta AAG Budhitresna Ade Reza Hariyadi Agung Pranoto Agus Joko Purwanto An Apriyani Tebiary Anak Agung Ayu Mirah Adi Anak Agung Gde Budhiarta Anak Agung Gde Budhiarta Anak Agung Gede Sudewa Djelantik Angga Yustiawan Anwar Santoso Ardi Nugroho Yulianto Aries Sulisetyono Aryana, I Gust Putu Suka Aryawan, Wasis Dwi Askandar Tjokroprawiro Astika, I Nyoman Buana Ma'ruf Buana Ma'ruf Budhiarta, Anak Agung Gde Dedi B. Purwanto Dewa Putu Gede Purwa Samatra Dian Purnamasari Dian Purnamasari Dikantoro, Regi Y. Djoenaidi Widjaja Djoko W. Soeatmadji Dwija Sanjaya Ericson Estrada Sipayung Gede Kambayana Gede Putu Arsana Gede Sukrawan Giles Anthony Thomas Gunanta, Julhari H Taniguchi H. S. Habiba Muhiddin, H. S. Habiba Hari Bagianto I Gde Raka Widiana I Gusti Agung Dewi Sarihati I Gusti Ayu Mardewi I Gusti Putu Suka Aryana I Ketut Aria Pria Utama I Made Bakta I Made Jawi I Made Jawi I Made Pande Dwipayana I Made Siswadi Semadi I Made Siswadi Semadi I Made Siswadi Semadi I Nengah Sujaya I Nyoman Astika I NYOMAN MANTIK ASTAWA I Nyoman Wande I Nyoman Wande I Putu Gede Adiatmika I Putu Gede Adiatmika I Wayan Mustika I Wayan Mustika I Wayan Putu Sutirta Yasa I Wayan Weta I Wayan Wita Ida Bagus Aditya Nugraha Ida Bagus Ekaputra Ida Bagus Ekaputra, Ida Bagus Ida Bagus Ngurah Wises Ida Bagus Putu Putrawan IGN Gunadi Ignatius Ferdi Yuatmadja IMR Saraswati Iswara, Ni Putu Ayu Astri Prana K Badjra Nadha K Rina K Tangking Widarsa Kadek Ngurah Hariawa Ketut Adi Jaya Sutana Ketut Suata Komang Ayu Kartika Sari Kusuma, Anak Agung Ngurah Jaya Luh Gede Sri Yenny Luh Seri Ani Made Ratna Saraswat MADE RATNA SARASWATI . Made Wardhana Made Wiryana Malik, Safarina G. Marisye Christantia N Kajiwara N. K. Niti Susila, N. K. Ni Ketut Rai Purnami Ni Made Suaniti Ni Nengah Dwi Fatmawati Ni Nyoman Trisna Yuliharti Tersinanda Ni Putu Ayu Astri Prana Iswara Noor Virliantarto Nurhadi Nurhadi Nym Astika Oktavianthi, Suksma Pradana Soewondo Purnami, Ni Ketut Rai Purwanto, Dedi B. Putra, Wing H. A. Putri Virliani Putri Virliani Putri Virliani R. A.T. Kuswardhani R. Prawira Bayu Putra Dewa Raka-Sudewi A. A. Regi Y. Dikantoro Regi Yudha Dikantoro S. Soetjiningsih, S. S., Hantono Setyawan, Dony Sidartawan Soegondo Siorcani, Putu Tasha Sri Trisnawati Sri Trisnawati Sri Yuniari Sri Yuniari, Sri Suastika, Arresta Vitasatria Sutanegara - Sutjahjo Suherman, Sutjahjo Teguh Putranto Thomas Eko Purwata Tuty Kuswardani W Wita Wasis Akriananta Wibowo Harso Nugroho Wibowo Nugroho, Wibowo Wing H. A. Putra Wira Gotera Wisnu Firstdhitama