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All Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Abdimas Mahakam Jurnal Ilmu Kesehatan Jurnal Riset Kefarmasian Indonesia Ahmar Metastasis Health Journal (AMHJ) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi Komunitas Jurnal Abdi Masyarakat Kita Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Rusdiati Helmidanora
Sekolah Tinggi Ilmu Kesehatan Samarinda
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Evaluasi Rasionalitas Penggunaan Favipiravir pada Pasien COVID-19 di Rumah Sakit Dirgahayu Samarinda Tahun 2022 Yason Lukius; Rusdiati Helmidanora; Heri Wijaya
Jurnal Farmasi Komunitas Vol. 11 No. 2 (2024): JURNAL FARMASI KOMUNITAS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfk.v11i2.56599

Abstract

Favipiravir merupakan antivirus yang dapat digunakan sebagai terapi pengobatan pada pasien COVID-19 apabila digunakan secara tepat. Tujuan dari penelitian ini untuk mengetahui rasionalitas penggunaan Favipiravir pada pasien COVID-19 di Rumah Sakit Dirgahayu Samarinda pada tahun 2022 berdasarkan kriteria tepat pasien, tepat diagnosis, tepat obat, tepat dosis, tepat interval waktu pemberian, tepat lama pemberian, dan waspada efek samping obat. Penelitian ini merupakan penelitian non eksperimental yang dilakukan dengan observasional deskriptif, teknik pengambilan sampel menggunakan metode total sampling secara retrospektif. Karakteristik pasien COVID-19 pada 53 sampel dalam penelitian ini sebesar 62,3% berusia 26-45 tahun, dengan dominasi pasien berjenis kelamin perempuan sebesar 71,7%, dan komorbid terbanyak adalah diabetes melitus yaitu sebesar 7,5%. Penentuan rasionalitas penggunaan Favipiravir dinilai berdasarkan pada literatur Informatorium Obat COVID-19 di Indonesia Edisi 4 dengan hasil tepat pasien (100,0%), tepat diagnosis (100,0%), tepat obat (100,0%), tepat dosis (83,0%), tepat interval waktu pemberian (100,0%), tepat lama pemberian (100,0%), dan telah waspada efek samping obat. Hasil penelitian ini menunjukkan bahwa penggunaan Favipiravir pada pasien COVID-19 di Rumah Sakit Dirgahayu Samarinda tahun 2022 telah rasional berdasarkan data rekam medis dan kriteria tepat pasien, tepat diagnosis, tepat obat, tepat dosis, tepat interval waktu pemberian, tepat lama pemberian dan waspada efek samping obat (6T1W).
EFEK HIPOTENSIF DARI ACEi DAN ARB PADA PASIEN DIABETES MELLITUS DAN HIPERTENSI DI RSUD. ABDUL WAHAB SYAHRANIE SAMARINDA Rusdiati Helmidanora; Triswanto Sentat
Jurnal Ilmiah Manuntung Vol 3 No 2 (2017): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v3i2.126

Abstract

More than two-thirds of patients with type 2 diabetes also experience hypertension whose development coincides with hyperglycemia, where each disease has a tendency to influence the increased risk of other diseases. Sundry new guidelines, such as the National Joint Committee 8, the American Diabetes Association recommend blood pressure targets in the diabetic population of <140/90 mmHg to reduce cardiovascular risk and prevent the progression of nephropathy. This study aims to determine whether there is a difference in achieving blood pressure target < 140/90 mmHg according to Join National Committee 8 between ACEi and ARB in patients with type 2 diabetes with hypertension. This research was conducted using a retrospective at internist clinic of Abdul Wahab Syahranie hospital, by taking secondary data from the medical record from blood pressure o 49 outpatients received a single antihypertensive either drug ACEi 29 people or ARB 34 people. This study showed that the achievement of target blood pressure by <140/90 mmHg (JNC 8 guideline) between ACEi 7 (28%) and ARB 5 (20,8%) group and it can be concluded that between ACEi and ARB drugs(P=0.5) there was no differsignificantly in achievement blood pressure target on type 2 diabetes with hypertension.
DRPs (DRUG RELATED PROBLEMS) PADA PENDERITA DIABETES MELLITUS DENGAN KOMPLIKASI GAGAL GINJAL DI RUMAH SAKIT UMUM DAERAH ‘X’ DI SAMARINDA PERIODE OKTOBER-DESEMBER 2016 Rusdiati Helmidanora; Muhammad Reza; Yullia Sukawaty
Jurnal Ilmiah Manuntung Vol 4 No 2 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v4i2.197

Abstract

Drug Related Problems (DRPs) is an unexpected event from the patient's experience because drug therapy can interfere with the success of healing. Patients with chronic disease for a long time have a chance of developing DRP. One chronic disease is diabetes mellitus which is a metabolic disorder due to lack of insulin production produced by the pancreas gland. Diabetic nephropathy is a microvascular complication that often occurs in type 1 and type 2 diabetes, due to high blood sugar levels that can cause kidney structure to change and impaired function. The aim of this study was to determine DRP in patients with diabetes with kidney failure. Research conducted was non-experimental research with data collection retrospectively. The data were analyzed by using standard reference books, Drug Information Handbooks. Based on the results of the study found DRPs in patients with DM with kidney failure in the inpatient installation of RSUD 'X' Samarinda in the period October-December 2016 who needed drugs but did not receive it (24%), received drugs without appropriate indications (11%), received wrong drugs (3%), dose was too low (0%), dose was too high (5%), the patient has ADR (13%), and compliance (0%).
A Quantitative Study Assessment of Public Knowledge Regarding Self-Medication with Ibuprofen In Marang Kayu District: A Quantitative Study Sentat, Triswanto; Nurjannah, Ika; Jubaidah, Siti; Wijaya, Heri; Helmidanora, Rusdiati
JSFK (Jurnal Sains Farmasi & Klinis) Vol 12 No 1 (2025): J Sains Farm Klin 12(1), April 2025
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.12.1.72-80.2025

Abstract

Self-medication is an approach widely used by the public to treat mild pain symptom by using over-the-counter medications without a prescription from physician. One of the medications that can be used for self-medication is Ibuprofen. Ibuprofen is a drug that can be used for self-medication; however, its use should be under the supervision and guidance of healthcare professionals. This study aims to determine the level of public knowledge regarding the self-medication use of ibuprofen in Marang Kayu District. This research uses a quantitative design with a descriptive approach. Data were collected through questionnaires distributed to 369 respondents selected using purposive sampling. The questionnaire included questions about knowledge aspects regarding ibuprofen and self-medication patterns. The study results showed that the level of public knowledge in Marang Kayu District about Ibuprofen for self-medication was 14.5% (49 respondents) with a high level of knowledge, 31.3% (106 respondents) with a moderate level of knowledge, and the majority, 54.3% (184 respondents), with a low level of knowledge. The results underscore the urgent need for targeted health education programs to improve public awareness and promote safe self-medication practices. Enhancing community knowledge is essential to minimize the risks associated with improper ibuprofen use and to encourage responsible drug consumption
Effect of Infusion Buas-Buas Leaf (Premna serratifolia Linn.) on Decreasing Blood Glucose Level of Alloxan-Induced White Mice Marliana, Anis; Helmidanora, Rusdiati
Jurnal Ilmu Kesehatan Vol 11 No 2 (2023): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v11i2.3786

Abstract

The prevalence of diabetes is incresing year by year, indicates that there is a need for diabetes treatment. One alternavite treatment for diabetes melitus uses traditional medicine which has relatively small effect when compared to synthetic diabetes melitus drugs use the long term. One plant buas-buas which is utilized a natural therapy to blood glucose levels leaves buas-buas (Premna serratifolia Linn). that are believe have antiabetic effect. The study was to determine infusion of buas-buas leaves can decreas blood glucose levels in alloxan-induced mice. The research is experimental using purposive sampling. Method collection sample, make simplisia of buas-buas leaves, extracing buas-buas leaves and antidiabetic test on 25 male white mice. The test was conducted by divid into 5 treatments groups, namely positive control (metformin), negative control (aquadest), and control treatment preparations with concentrations of 10, 20, and 40 %. Mice were induced alloxan with dose of 200 mg/kg BB intraperitoneally and give after blood glucose levels 200 mg/dL, then measurd blood glucose levels of mice on day 7 and day 14. The data result were analyzed using Kruskall Wallis Test. The results of study indicate that infusion of wild buas leaves can decreas blood glucose levels. A dose of wild buas leaf infusion with a concentration of 20 % is effective in decreasing blood glucose levels.
Tingkat Pengetahuan Mahasiswa Program Studi Farmasi Sekolah Tinggi Ilmu Kesehatan Samarinda tentang Beyond Use Date (BUD) Obat Kharisma Duratul Hikmah; Wijaya, Heri; Helmidanora, Rusdiati
Jurnal Farmasi Komunitas Vol. 12 No. 2 (2025): JURNAL FARMASI KOMUNITAS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfk.v12i2.58520

Abstract

Beyond Use Date (BUD) merupakan batas waktu penggunaan sediaan obat setelah obat diracik, dicampur, atau kemasan primernya dibuka, yang ditetapkan berdasarkan stabilitas fisik-kimia dan risiko kontaminasi mikroba. Pengetahuan tentang BUD penting bagi mahasiswa farmasi sebagai calon tenaga kefarmasian untuk menjamin keamanan dan efektivitas obat yang digunakan pasien. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan mahasiswa Program Studi Farmasi Sekolah Tinggi Ilmu Kesehatan Samarinda tentang BUD obat, serta menganalisis perbedaan pengetahuan antara mahasiswa Sarjana Farmasi dan Diploma III Farmasi. Penelitian ini merupakan studi deskriptif dengan pendekatan cross-sectional menggunakan metode total sampling, melibatkan 656 mahasiswa sebagai responden. Pengumpulan data dilakukan pada Januari–Maret 2024 menggunakan kuesioner terstruktur. Hasil menunjukkan bahwa 21,03% mahasiswa memiliki pengetahuan yang baik, 61,74% cukup, dan 17,23% kurang. Secara umum, tingkat pengetahuan mahasiswa berada dalam kategori cukup. Hasil uji statistik (Mann-Whitney) menunjukkan tidak terdapat perbedaan signifikan tingkat pengetahuan antara mahasiswa Sarjana Farmasi dan Diploma III Farmasi (p > 0,05). Pengetahuan mahasiswa tentang BUD obat masih perlu ditingkatkan, terutama melalui integrasi materi BUD dalam kurikulum, kegiatan praktikum, serta penyuluhan dalam praktik kefarmasian untuk meningkatkan pemahaman dan kesiapan mereka dalam pelayanan obat yang aman.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK BUNGA KECOMBRANG (Etlingera elatior (Jack) R. M.Sm.) TERHADAP BAKTERI Staphylococcus aureus Sp. Rusdiati Helmidanora; Yullia Sukawaty; Divya Miranti; Tria Prayoga; Nia Lisnawati
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 10 No. 1 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i1.769

Abstract

Kecombrang plant contains essential oils which are bioactive, including 0.0735% in the leaves. in flowers 0.0334%, in stems 0.0029% and in rhizomes 0.0021%. Combrang flowers (Etlingera elatior (Jack)) have effective antibacterial activity. The aim of this research was to determine the level of ethanol extract of kecombrang flowers from Pampang village (100-500 masl), East Kalimantan in inhibiting Staphylococcus aureus bacteria. The object studied was the inhibitory zone of kecombrang flower extract against Staphylococcus aureus bacteria. Extract preparation was carried out using the maceration method using 96% ethanol solvent, antibacterial activity testing was carried out using the well method with extract concentrations of 10%, 20%, 40%, 60% and positive control chloramphenicol and negative control DMSO. The results of this study were that 96% ethanol extract of kecombrang flowers had antibacterial activity against Staphylococcus aureus bacteria with a maximum concentration of 60% and had a medium category inhibitory power of 5.933 mm.
KADAR FLAVONOID EKSTRAK ETANOL BUNGA TELANG (Clitoria ternatea L.) BERDASARKAN VARIASI KONSENTRASI PELARUT ETANOL Henny Nurhasnawati; Risa Supriningrum; Rusdiati Helmidanora; Margareta, Sully
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 11 No. 2 (2025): Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v11i2.921

Abstract

Butterfly pea (Clitoria ternatea L.) is a plant used for medicinal purposes, including therapeutic, cosmetic, nutritional, and beauty applications. Flavonoids, as secondary metabolites with diverse chemical structures in plants, perform various important functions. These functions include growth regulation, coloration, protection from UV rays, and roles in defense mechanisms and signaling systems with microorganisms. These compounds also have pharmacological effects as antidiabetics, antioxidants, and antibacterials. Solvent concentration plays an important role, as it can affect the amount of active compounds extracted from natural materials. The purpose of this study was to determine the flavonoid content in butterfly pea flower extracts using ethanol solvents at concentrations of 50%, 70%, and 95%. The results of phytochemical screening tests showed that all extracts contained secondary metabolites in the form of flavonoids. Other parameters analyzed included yield, moisture content, and flavonoid content from the three ethanol concentration variations. The yields obtained were 57.14%, 54.08%, and 40.72%, respectively, while the moisture content was 9.44 ± 2.17%, 8.99 ± 2.12%, and 7.75 ± 1.97%, respectively.The highest flavonoid content was obtained in the extract with 95% ethanol solvent at 1.2939 ± 0.0880%, followed by 70% ethanol at 0.6958 ± 0.0573%, and 50% ethanol at 0.5811 ± 0.0142%. Statistical analysis using ANOVA showed that there were differences in flavonoid content between the ethanol concentration variation groups
Co-Authors Anastasia Reni Mangalik Andri Priyoherianto Chairunnisa Chairunnisa Chairunnisa Chairunnisa Divya Miranti Elly Purwati Endah Handayani Fitri Handayani Hayatus Sa'adah Hayatus Sa’adah Henny Nurhasnawati Heri Wijaya Heri Wijaya, Heri Husnul Warnida Husnul Warnidah Ika Nurjannah, Ika Is alukal Fauziah A.A Kharisma Duratul Hikmah Margareta, Sully Marliana, Anis Muhammad Reza Muhammad Reza Nia Lisnawati Prayoga, Tria Risa Supriningrum Siti Jubaidah Siti Jubaidah, Siti Sukawaty, Yullia Sukawaty, Yullia Triswanto Sentat Yason Lukius Yullia Sukawaty Yullia Sukawaty Yullia Sukawaty Yullia Sukawaty