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All Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Ilmu Kesehatan Jurnal Riset Kefarmasian Indonesia Ahmar Metastasis Health Journal (AMHJ) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi Komunitas Jurnal Abdi Masyarakat Kita Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Jurnal Abdimas Mahakam
Rusdiati Helmidanora
Sekolah Tinggi Ilmu Kesehatan Samarinda
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DRPs (DRUG RELATED PROBLEMS) PADA PENDERITA DIABETES MELLITUS DENGAN KOMPLIKASI GAGAL GINJAL DI RUMAH SAKIT UMUM DAERAH ‘X’ DI SAMARINDA PERIODE OKTOBER-DESEMBER 2016 Rusdiati Helmidanora; Muhammad Reza; Yullia Sukawaty
Jurnal Ilmiah Manuntung Vol 4 No 2 (2018): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v4i2.197

Abstract

Drug Related Problems (DRPs) is an unexpected event from the patient's experience because drug therapy can interfere with the success of healing. Patients with chronic disease for a long time have a chance of developing DRP. One chronic disease is diabetes mellitus which is a metabolic disorder due to lack of insulin production produced by the pancreas gland. Diabetic nephropathy is a microvascular complication that often occurs in type 1 and type 2 diabetes, due to high blood sugar levels that can cause kidney structure to change and impaired function. The aim of this study was to determine DRP in patients with diabetes with kidney failure. Research conducted was non-experimental research with data collection retrospectively. The data were analyzed by using standard reference books, Drug Information Handbooks. Based on the results of the study found DRPs in patients with DM with kidney failure in the inpatient installation of RSUD 'X' Samarinda in the period October-December 2016 who needed drugs but did not receive it (24%), received drugs without appropriate indications (11%), received wrong drugs (3%), dose was too low (0%), dose was too high (5%), the patient has ADR (13%), and compliance (0%).
A Quantitative Study Assessment of Public Knowledge Regarding Self-Medication with Ibuprofen In Marang Kayu District: A Quantitative Study Sentat, Triswanto; Nurjannah, Ika; Jubaidah, Siti; Wijaya, Heri; Helmidanora, Rusdiati
JSFK (Jurnal Sains Farmasi & Klinis) Vol 12 No 1 (2025): J Sains Farm Klin 12(1), April 2025
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.12.1.72-80.2025

Abstract

Self-medication is an approach widely used by the public to treat mild pain symptom by using over-the-counter medications without a prescription from physician. One of the medications that can be used for self-medication is Ibuprofen. Ibuprofen is a drug that can be used for self-medication; however, its use should be under the supervision and guidance of healthcare professionals. This study aims to determine the level of public knowledge regarding the self-medication use of ibuprofen in Marang Kayu District. This research uses a quantitative design with a descriptive approach. Data were collected through questionnaires distributed to 369 respondents selected using purposive sampling. The questionnaire included questions about knowledge aspects regarding ibuprofen and self-medication patterns. The study results showed that the level of public knowledge in Marang Kayu District about Ibuprofen for self-medication was 14.5% (49 respondents) with a high level of knowledge, 31.3% (106 respondents) with a moderate level of knowledge, and the majority, 54.3% (184 respondents), with a low level of knowledge. The results underscore the urgent need for targeted health education programs to improve public awareness and promote safe self-medication practices. Enhancing community knowledge is essential to minimize the risks associated with improper ibuprofen use and to encourage responsible drug consumption
Effect of Infusion Buas-Buas Leaf (Premna serratifolia Linn.) on Decreasing Blood Glucose Level of Alloxan-Induced White Mice Marliana, Anis; Helmidanora, Rusdiati
Jurnal Ilmu Kesehatan Vol 11 No 2 (2023): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v11i2.3786

Abstract

The prevalence of diabetes is incresing year by year, indicates that there is a need for diabetes treatment. One alternavite treatment for diabetes melitus uses traditional medicine which has relatively small effect when compared to synthetic diabetes melitus drugs use the long term. One plant buas-buas which is utilized a natural therapy to blood glucose levels leaves buas-buas (Premna serratifolia Linn). that are believe have antiabetic effect. The study was to determine infusion of buas-buas leaves can decreas blood glucose levels in alloxan-induced mice. The research is experimental using purposive sampling. Method collection sample, make simplisia of buas-buas leaves, extracing buas-buas leaves and antidiabetic test on 25 male white mice. The test was conducted by divid into 5 treatments groups, namely positive control (metformin), negative control (aquadest), and control treatment preparations with concentrations of 10, 20, and 40 %. Mice were induced alloxan with dose of 200 mg/kg BB intraperitoneally and give after blood glucose levels 200 mg/dL, then measurd blood glucose levels of mice on day 7 and day 14. The data result were analyzed using Kruskall Wallis Test. The results of study indicate that infusion of wild buas leaves can decreas blood glucose levels. A dose of wild buas leaf infusion with a concentration of 20 % is effective in decreasing blood glucose levels.
Tingkat Pengetahuan Mahasiswa Program Studi Farmasi Sekolah Tinggi Ilmu Kesehatan Samarinda tentang Beyond Use Date (BUD) Obat Kharisma Duratul Hikmah; Wijaya, Heri; Helmidanora, Rusdiati
Jurnal Farmasi Komunitas Vol. 12 No. 2 (2025): JURNAL FARMASI KOMUNITAS
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfk.v12i2.58520

Abstract

Beyond Use Date (BUD) merupakan batas waktu penggunaan sediaan obat setelah obat diracik, dicampur, atau kemasan primernya dibuka, yang ditetapkan berdasarkan stabilitas fisik-kimia dan risiko kontaminasi mikroba. Pengetahuan tentang BUD penting bagi mahasiswa farmasi sebagai calon tenaga kefarmasian untuk menjamin keamanan dan efektivitas obat yang digunakan pasien. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan mahasiswa Program Studi Farmasi Sekolah Tinggi Ilmu Kesehatan Samarinda tentang BUD obat, serta menganalisis perbedaan pengetahuan antara mahasiswa Sarjana Farmasi dan Diploma III Farmasi. Penelitian ini merupakan studi deskriptif dengan pendekatan cross-sectional menggunakan metode total sampling, melibatkan 656 mahasiswa sebagai responden. Pengumpulan data dilakukan pada Januari–Maret 2024 menggunakan kuesioner terstruktur. Hasil menunjukkan bahwa 21,03% mahasiswa memiliki pengetahuan yang baik, 61,74% cukup, dan 17,23% kurang. Secara umum, tingkat pengetahuan mahasiswa berada dalam kategori cukup. Hasil uji statistik (Mann-Whitney) menunjukkan tidak terdapat perbedaan signifikan tingkat pengetahuan antara mahasiswa Sarjana Farmasi dan Diploma III Farmasi (p > 0,05). Pengetahuan mahasiswa tentang BUD obat masih perlu ditingkatkan, terutama melalui integrasi materi BUD dalam kurikulum, kegiatan praktikum, serta penyuluhan dalam praktik kefarmasian untuk meningkatkan pemahaman dan kesiapan mereka dalam pelayanan obat yang aman.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK BUNGA KECOMBRANG (Etlingera elatior (Jack) R. M.Sm.) TERHADAP BAKTERI Staphylococcus aureus Sp. Rusdiati Helmidanora; Yullia Sukawaty; Divya Miranti; Tria Prayoga; Nia Lisnawati
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 10 No. 1 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i1.769

Abstract

Kecombrang plant contains essential oils which are bioactive, including 0.0735% in the leaves. in flowers 0.0334%, in stems 0.0029% and in rhizomes 0.0021%. Combrang flowers (Etlingera elatior (Jack)) have effective antibacterial activity. The aim of this research was to determine the level of ethanol extract of kecombrang flowers from Pampang village (100-500 masl), East Kalimantan in inhibiting Staphylococcus aureus bacteria. The object studied was the inhibitory zone of kecombrang flower extract against Staphylococcus aureus bacteria. Extract preparation was carried out using the maceration method using 96% ethanol solvent, antibacterial activity testing was carried out using the well method with extract concentrations of 10%, 20%, 40%, 60% and positive control chloramphenicol and negative control DMSO. The results of this study were that 96% ethanol extract of kecombrang flowers had antibacterial activity against Staphylococcus aureus bacteria with a maximum concentration of 60% and had a medium category inhibitory power of 5.933 mm.
KADAR FLAVONOID EKSTRAK ETANOL BUNGA TELANG (Clitoria ternatea L.) BERDASARKAN VARIASI KONSENTRASI PELARUT ETANOL Henny Nurhasnawati; Risa Supriningrum; Rusdiati Helmidanora; Margareta, Sully
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 11 No. 2 (2025): Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v11i2.921

Abstract

Butterfly pea (Clitoria ternatea L.) is a plant used for medicinal purposes, including therapeutic, cosmetic, nutritional, and beauty applications. Flavonoids, as secondary metabolites with diverse chemical structures in plants, perform various important functions. These functions include growth regulation, coloration, protection from UV rays, and roles in defense mechanisms and signaling systems with microorganisms. These compounds also have pharmacological effects as antidiabetics, antioxidants, and antibacterials. Solvent concentration plays an important role, as it can affect the amount of active compounds extracted from natural materials. The purpose of this study was to determine the flavonoid content in butterfly pea flower extracts using ethanol solvents at concentrations of 50%, 70%, and 95%. The results of phytochemical screening tests showed that all extracts contained secondary metabolites in the form of flavonoids. Other parameters analyzed included yield, moisture content, and flavonoid content from the three ethanol concentration variations. The yields obtained were 57.14%, 54.08%, and 40.72%, respectively, while the moisture content was 9.44 ± 2.17%, 8.99 ± 2.12%, and 7.75 ± 1.97%, respectively.The highest flavonoid content was obtained in the extract with 95% ethanol solvent at 1.2939 ± 0.0880%, followed by 70% ethanol at 0.6958 ± 0.0573%, and 50% ethanol at 0.5811 ± 0.0142%. Statistical analysis using ANOVA showed that there were differences in flavonoid content between the ethanol concentration variation groups
FORMULASI SEDIAAN SPRAY GEL EKSTRAK DAUN BANDOTAN (Ageratum conyzoides.L) SEBAGAI ANTINYAMUK Mangalik, Anastasia Reni; Helmidanora, Rusdiati; Sa'adah, Hayatus
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 2 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i2.364

Abstract

There are many types of mosquitoes that cause disease in humans, one of which is the Anopheles mosquito that spreads malaria. Bandotan plants are used to treat colic, flu, fever, antidiarrheal, diarrhoea. The purpose of this study was to determine the concentration of bandotan (Ageratum conyzoides.L) leaf extract that provides the best physical properties and anti-mosquito activity in spray gel preparations. The research method conducted was experimental. The object studied was the formulation of bandotan leaf preparation as an antinyamite. The research stages include plant determination, sample collection, simplisia preparation, extraction using maceration method with 70% ethanol solvent, identification of secondary metabolite compounds, preparation of spray gel formula, and preparation evaluation. Bandotan leaf extract was formulated into anti-mosquito spray gel preparations with concentration variants of 10%, 15%, 20%, and using positive control of X brand anti-mosquito spray as a comparison. The preparation testing included organoleptic test, homogeneity test, pH test, viscosity test, and mosquito repellency test. The results of data collection were analysed statistically. A good preparation formula is found in the negative control formula because it has a stable consistency and pH. The results showed that the ethanol extract of bandotan leaves was not significantly different from the organoleptic test, homogeneity test, viscosity test, and pH test. The greatest mosquito repellency was at a concentration of 20% which was 66.33%, at concentrations of 10% and 15% had an average anti-mosquito activity of 22.83% and 57.83% respectively for the positive control with brand X of 99.30%.
FORMULASI KAPSUL ANTIDIABETES EKSTRAK UMBI BAWANG DAYAK (Eleuhterine palmifolia (L) Merr.) DENGAN VARIASI KONSENTRASI AVICEL 101 DAN PREGELATINIZED STARCH Indriawan, Kadek Agus; Sa'adah, Hayatus; Helmidanora, Rusdiati
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 3 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v5i3.402

Abstract

Diabetes Mellitus is a heterogeneous disease characterized by improvement glucose levels in the blood. Several studies have shown that Dayak onions have hypoglycemic activity or lowering blood glucose levels which may be very useful for treatment of diabetes mellitus. Flavonoids contained in Dayak onions are in position to restore the characteristics of pancreatic tissue by increasing insulin release through β cells, so that it can lower blood sugar levels and can also increase sensitivity peripheral cells to insulin. Given the great potential of Dayak onions as antidiabetic, it is very important to develop more practical preparations that can carrying out weight uniform measurements of the products used, of course, one of them is in pharmaceutical preparations capsule form. This examination aims to determine the physical properties and antioxidant activity of Dayak onion extract capsules in large quantities concentration of Avicel PH 101 and pregelatinized starch as fillers. Look was carried out experimentally using three formulas with various concentrations fillers with a ratio between Avicel PH 101 and pregelatinized starch, in particular formula I (1:0), formulation II (0.5:0.5) and method III (0:1). body residence and drug stability is checked and then tested for antioxidant hobby spectrophotometric use. The research results show that the formula with the composition of Avicel PH 101 and pregelatinized starch in the ratio (0:1) is given the best wet house physical test results were 3.4%, sliding houses 12.82 gram/second, angle of repose 29.85⁰, compressibility 8%, density 0.544 and destroyed time 3 minutes 37 seconds. along with antioxidant effects activity examination showed that the drug Dayak onion extract proved to be moderate antioxidant activity, specifically 228.78 ppm.  
GAMBARAN PENGADAAN OBAT E-PURCHASING UNTUK PASIEN PROGRAM RUJUK BALIK DI APOTEK KIMIA FARMA SAMARINDA Islami, Vita Hani; Ansyori, Achmad Kadri; Helmidanora, Rusdiati
Jurnal Riset Kefarmasian Indonesia Vol. 5 No. 3 (2023): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/0whwam97

Abstract

Procurement plays an important role in the drug management cycle. Efforts to improve performance and efficiency in the drug procurement process, both for the JKN program and other health programs, procurement of drugs and medical devices must use an e-catalogue. The Refer Back Program (PRB) is BPJS Health's flagship program. Kimia Farma Pharmacy is a network pharmacy for the Refer Back Program. Kimia Farma Samarinda Pharmacy, in the procurement of PRB medicines has used e-purchasing and there are still obstacles found in the procurement system such as long lead times, unavailability of medicines at distributors, and price uniformity resulting in shortages of medicines which have a negative impact on the availability of medicines for patients referral program. This research aims to determine the management of drug availability using e-purchasing for referral program patients at Kimia Farma Samarinda Pharmacy. This research is qualitative research with a case study approach. The research was carried out by collecting primary data obtained through in-depth interviews with respondents who were deemed to know and be involved in the procurement and/or management process of medicines at Kimia Farma Pharmacy No. 114 Samarinda. Secondary data was obtained through observing documents related to drug procurement at Kimia Farma Pharmacy No. 114 Samarinda. Research results obtained from Kimia Farma Pharmacy No. 114 Samarinda show that the level of drug availability at Kimia Farma Pharmacy No. 114 Samarinda is still low (14.33%). The availability of PRB drugs in pharmacies is not sufficient to meet the needs of PRB participants. Drug vacancies are mostly caused by vacancies from distributors. To avoid patients not getting medicine, pharmacies borrow medicine from other Kimia Farma pharmacies or reduce the amount of medicine given to patients.
Pelatihan Pembuatan Hand Sanitizer di Kantor Dinas Perindustrian Kota Samarinda Risa Supriningrum; Hayatus Sa’adah; Rusdiati Helmidanora
Jurnal Abdimas Mahakam Vol. 5 No. 01 (2021): Januari
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sejak terjadinya pandemi covid 19 ketersediaan hand sanitizer di Indonesia menjadi sangat langka di pasaran, dikarenakan banyak orang yang membeli barang tersebut secara berlebihan. Pemerintah menghimbau kepada masyarakat untuk selalu menjaga kebersihan tangan dengan rajin mencuci tangan menggunakan sabun atau menggunakan hand sanitizer sebagai salah satu upaya mencegah penularan covid 19. Pembersih tangan (hand sanitizer) memiliki kemampuan menghambat hingga membunuh bakteri. Tujuan dilakukannya pengabdian masyarakat ini adalah memberikan pelatihan kepada masyarakat cara membuat hand sanitizer dari bahan sintetis dan bahan alam. Formula hand sanitizer dari bahan sintetis berupa alkohol 96%, hydrogen peroksida, gliserin dan aquades. Sedangkan formula hand sanitizer dari bahan alam berupa daun sirih, jeruk nipis dan aquades. Kegiatan ini merupakan kerjasama antara Dinas Perindustrian, Perdagangan, Koperasi, Usaha Kecil dan Menengah Provinsi Kalimantan Timur dengan Sekolah Tinggi Ilmu Kesehatan Samarinda. Peserta pada kegiatan ini adalah perwakilan warga Kelurahan Karang Asam Ilir, Kelurahan Sempaja Utara dan Kelurahan Sungai Kapih. Metode yang digunakan pada pengabdian masyarakat meliputi ceramah tentang pentingnya menjaga kebersihan tangan, pengertian hand sanitizer, uraian bahan yang digunakan, dilanjutkan demonstrasi dan bimbingan. Kegiatan ini didanai oleh Desperidagkop UKM Provinsi Kalimantan Timur. Harapan dengan dilaksanakan pelatihan ini ialah masyarakat dari kelurahan yang menjadi peserta lebih peduli dengan kebersihan dan dapat memenuhi kebutuhan hand sanitizer untuk keluarga dan masyarakat sekitarnya.
Co-Authors Anastasia Reni Mangalik Andri Priyoherianto Ansyori, Achmad Kadri Chairunnisa Chairunnisa Chairunnisa Chairunnisa Divya Miranti Elly Purwati Endah Handayani Fitri Handayani Hayatus Sa'adah Hayatus Sa`adah Hayatus Sa’adah Henny Nurhasnawati Heri Wijaya Heri Wijaya, Heri Husnul Warnida Husnul Warnidah Ika Nurjannah, Ika Indriawan, Kadek Agus Is alukal Fauziah A.A Islami, Vita Hani Kharisma Duratul Hikmah Mangalik, Anastasia Reni Margareta, Sully Marliana, Anis Muhammad Reza Muhammad Reza Nia Lisnawati Prayoga, Tria Risa Supriningrum Siti Jubaidah Siti Jubaidah, Siti Sukawaty, Yullia Sukawaty, Yullia Triswanto Sentat Yason Lukius Yullia Sukawaty Yullia Sukawaty Yullia Sukawaty Yullia Sukawaty