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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Nusantara Hasana Journal Jurnal Ilmiah Kesehatan Masyarakat Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) Jurnal Pengabdian Ilmu Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Ardhi: Jurnal Pengabdian dalam Negri The Journal General Health and Pharmaceutical Sciences Research Journal of Clinical Pharmacy and Pharmaceutical Science Galen: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Professional Evidence-based Research and Advances in Wellness and Treatment
Delladari Mayefis
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

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Tingkat Kepuasan Pasien Rawat Jalan Peserta Jaminan Kesehatan Nasional Terhadap Pelayanan Kefarmasian di Puskesmas Sekupang Kota Batam Habibie Deswilyaz Ghiffari; Delladari Mayefis; Reni Novianti
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 1 No. 4 (2022): Oktober 2022
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v1i4.954

Abstract

Puskesmas is a health service facility that organizes public health efforts and individual health efforts at the first level. In an effort to improve pharmacy services at the puskesmas, evaluation needs to be done by assessing patient satisfaction. The purpose of this study is to assess the satisfaction of National Health Insurance patients with pharmacy services at the puskesmas. This research was conducted for National Health Insurance patients who make up for drugs at Sekupang city of Batam. This type of research is descriptive research using a questionnaire research instrument. Data were processed using a Likert scale and the results of the study showed that the highest level of patient satisfaction with Pharmaceutical Services at Sekupang Health Center in Batam City was found in the  empathy variable (hospitality). In this study in general the results obtained from outpatient satisfaction of participants in the national health guarantee were very satisfying for respondents (85.86%).
Penetapan Kadar Fenolik Total Ekstrak Daun Jotang (Sphagneticola Trilobata) Dengan Spektrofotometri UV-Vis Ghalib Syukrillah Syahputra; Delladari Mayefis; Tommy Julianto; Lyna Elvira
JURNAL RISET RUMPUN ILMU KESEHATAN Vol. 2 No. 1 (2023): April : Jurnal Riset Rumpun Ilmu Kesehatan
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrikes.v2i1.2669

Abstract

Phenolic compounds are the largest group of compounds that act as natural antioxidants in plants. One of the plants that has the potential as a natural antioxidant is Jotang (Sphagneticola trilobata). This study aims to determine whether jotang leaf extract (Sphagneticola trilobata) has phenolic content and to determine the total phenolic content in jotang leaf extract (Sphagneticola trilobata). Jotang leaves were extracted by maceration method using methanol solvent. The method of determining total phenolic content was carried out using Folin-ciocaltaeu reagent because phenolic compounds can react with Folin-Ciocalteu to form a solution that can be measured absorbance. As a standard solution, gallic acid is used which is reacted with Folin-Ciocalteau reagent to produce a yellow color indicating that it contains phenolics, after which it is added with Na₂CO₃ solution as a base atmosphere giver. The phytochemical screening of jotang leaf extract showed positive results containing flavonoids, alkaloids, saponins, phenolic compounds, and triterpenoids. Determination of the wavelength of gallic acid obtained maximum 653 nm. The results showed that jotang leaf extract (Sphagneticola trilobata) has phenolic content and obtained total phenolic content of jotang leaf extract of 0.909 mg /g.
Uji Aktivitas Antibakteri Fraksi Ekstrak Daun Jotang (Sphagneticola trilobata L) terhadap Bakteri Eschericia coli Ghalib Syukrillah Syahputra; Ibnu Rusyd; Arie Vonikartika; Zahara Zahara; Eka Febriyanti; Delladari Mayefis
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 4 No. 1 (2025): Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v4i1.58

Abstract

Jotang (Sphagneticola trilobata) is a wild plant that has antibacterial potential. This study aims to determine the antibacterial activity of the n-hexane, ethyl acetate and methanol fractions of jotang leaf extract against Escherichia coli bacteria. Jotang leaves were extracted using methanol by maceration extraction method, followed by the fractionation stage using Liquid-Liquid Extraction method. The fractionation process uses n-hexane, ethyl acetate and methanol as solvents. Next step, each fraction was tested for antibacterial activity using the disc diffusion method. The concentrations of each fraction used were 200 µg/disc, 400 µg/disc, and 1000 µg/disc, positive control used chloramphenicol and negative control used DMSO 10%. The Result showed the most potential antibacterial activity of the active fraction from jotang leaves extract was the n-hexane fraction.
AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN GAHARU ( Aquilaria malaccensis Lamk ) PADA MENCIT PUTIH JANTAN ( Mus Musculus ) Delladari Mayefis; Cindy Octavia; Sri Hainil; Rury Trisa Utami; Desy Maniarti Gusmali; Hesti Marliza; Nurliyasman, Nurliyasman
Nusantara Hasana Journal Vol. 4 No. 12 (2025): Nusantara Hasana Journal, May 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v4i12.1413

Abstract

Inflammation is a complex response that occurs in blood vessel tissue due to external or internal stimuli. One plant that is known to have anti-inflammatory properties is agarwood leaves (Aquilaria malaccensis Lam). This study aims to evaluate the effect of ethanol extract from gaharu leaves on anti-inflammatory activity in male white mice (Mus musculus) and to determine the most effective dose. The experimental animals were divided into five groups, including a control group that received Na CMC and diclofenac sodium. Inflammation induction was carried out through injection of egg white solution, and measurements were carried out periodically for six hours. The analysis results showed that a dose of 300 mg/KgBW of agarwood leaf extract provided the most significant anti-inflammatory effect compared to lower doses. 100 mg/kgBB and 200 mg/kgBB
UJI AKTIVITAS ANTIBAKTERI DARI EKSTRAK ETANOL DAUN MANGKOKAN (Polyscias Scutellaria) TERHADAP BAKTERI Bacillus cereus DAN Shigella dysentriae Sri Hainil; Rury Trisa Utami; Delladari Mayefis; Nurul Asiqin
Nusantara Hasana Journal Vol. 5 No. 5 (2025): Nusantara Hasana Journal, October 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i5.1710

Abstract

Mangkokan leaves (Polyscias scutellaria) are medicinal plants believed to treat the digestive tract, such as diarrhea, and abdominal pain, to use it by drinking a decoction of Mangkokan leaves as a traditional medicine. This study aims to determine the antibacterial activity of ethanol extract of Polyscias scutellaria leaves in inhibiting the growth of Bacillus cereus and Shigella dysentriae bacteria. The active compounds in Mangkokan leaves contain alkaloids, saponins, phenolics, and steroids. These ingredients can function as antibacterial. This study was carried out by maceration method using 96% ethanol solvent, and the viscous extract obtained tested to see the inhibition in Bacillus cereus and Shigella dysenteriae bacteria using the disc paper diffusion method with concentrations of 25%, 50%, 75%, and 100%. The positive control was chloramphenicol 30 μg/disk, and the negative control was DMSO 5% (Dimethylsulfoxide). The test results showed that Mangkokan leaf ethanol extract had antibacterial activity against Bacillus cereus bacteria with a (moderate) inhibitory response at a concentration of 100% of 7.96 mm. In comparison, Shigella dysentriae has an inhibitory response (moderate) at a concentration of 100% of 7.68 mm
Aktivitas Antiseptik Lotion Kombinasi Ekstrak Herbal Pegagan (Centella Asiatica (L.) Urban Dan Aloe Vera Terhadap Bakteri Pseudomonas Aeruginosa Delladari Mayefis; Rury Trisa Utami
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 1 No. 3 (2021): NOVEMBER : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v1i3.2931

Abstract

Pseudomonas aeruginosa is a bacterium that can cause a variety of diseases, one of which is an infection with the skin. Where one of the ways to prevent infections of the skin is by hand washing, one of them uses antiseptic. The study aims to test the antibacterial ativity of the gel antiseptic, a combination of Centella Asiatica extract and aloe vera extract against Pseudomonas aeruginosabacteria. This research uses a method of diffuse diffusion with the concentration of a combination of Centella asiatica and Aloe vera extract is 5%: 5% (f IV), 7.5%: 2.5% (f V), 7.5%: 2.5% (f VI), with positive control using an antiseptic antic. Antibacterial activity with an antiseptic combination of Centella Asiatica herbal extract and aloe vera against Pseudomonas aeruginosa bacteria has a moderate-to-medium catfisher inhibition of 18.06 mm. Based on statistical tests using ANOVA indicates there is a significant difference between the average percentage value between groups (sig ≤ 0.05).
Uji Efek Stimulan Sistem Saraf Pusat Dari Ekstrak Etanol Biji Pala (Myristica fragrans H.) Pada Mencit Putih Jantan Delladari Mayefis; Shinta Sari Dewi; Nurlia Oktaviyanti; Arie Vonikartika
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 1 No. 2 (2021): JULI : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v1i2.2943

Abstract

Research on the effects of central nervous system stimulants from nutmeg (Myristica Fragrans H.) ethanol extract on male white mice has been carried out using the methods of: sleep onset test, hanging test, swimming test, and evacuation test. In this study, the test animals were divided into five groups in which each group consisted of three animals for three experiments, the first group was given a 0.5% NaC CMC suspention, the next three groups were given extracts of nutmeg seed ethanol (Myristica Fragrans H. ) with three variations of doses, namely 150, 300, and 600 mg / Kg BW, the next group as a comparison was given a caffeine solution of 13 mg / kg BW. Each preparation was given orally and then carried out a observation of several test methods. The results showed that the ethanol extract of nutmeg (Pala H.) can provide a good stimulant effect at a dose of 300 mg / kg BW (p <0.05) which was clearly seen in the swimming test and the hanging test method.
Uji Aktivitas Ekstrak Etanol Daun Beriang (Ploiarium elegans korth ) Secara In Vivo sebagai Antidiabetes pada Mencit Putih Jantan (Mus Musculus) Rina Yunita; Delladari Mayefis; Aprilya Sri Rachmayanti
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 1 (2026): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v2i1.116

Abstract

Diabetes melitus merupakan suatu keadaan dimana gula darah dalam keadaan tinggi atau diatas normal dan perlahan namun pasti akan merusak jaringan dalam tubuh jika tidak ditangani secara tepat. Salah satu tumbuhan yang berpotensi untuk pengobatan tradisional sebagai antidiabetes adalah Beriang (Ploiarium elegans korth). Senyawa yang terkandung dalam daun beriang adalah alkaloid, flavonoid, tannin, saponin dan triterpenoid. Tujuan penelitian ini untuk mengetahui pengaruh pemberian ekstrak etanol daun Beriang (Ploiarium elegans korth) dalam menurunkan kadar glukosa darah pada mencit putih jantan (Mus musculus). Metode yang digunakan dalam pengujian aktivitas antidiabetes ialah tes toleransi glukosa dengan mengamati aktivitas penurunan kadar glukosa pada mencit putih Jantan (Mus musculus) dengan dosis 100 mg/kg BB, 200 mg/kg BB, dan 300 mg/kg BB yang di induksi aloksan. Hasil penelitian ini menunjukkan bahwa daun Beriang memiliki aktivitas menurunkan kadar glukosa darah pada mencit hiperglikemia dengan rata-rata persentase dosis ekstrak daun Beriang 100 mg/kgBB yaitu 30,18%, 200 mg/kgBB yaitu 35,32%, dan 300 mg/kgBB yaitu 54,57%. Dari hasil tersebut dapat dikatakan bahwa pemberian ekstrak etanol daun beriang dapat menurunkan kadar glukosa darah secara signifikan yang ditunjukkan oleh hewan uji mencit.
The Influence of Interpersonal Communication, Professionalism and Competence on The Monitoring System and Hospital Paramedic Performance at Dr. H. Soewondo Kendal Regional Hospital Anindita Paramastuti Azuma; Hindyah Ike Suhariati; Raden Roro Ratuningrum Anggorodiputro; Delladari Mayefis; Nelwetis
Professional Evidence-based Research and Advances in Wellness and Treatment Vol. 2 No. 2 (2025): April, 2025
Publisher : CV. Get Press Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69855/perawat.v2i2.141

Abstract

The performance of paramedics, especially nurses and midwives, is essential to the quality of hospital health services. This study aims to examine the influence of interpersonal communication, professionalism, and competence on the monitoring system and nurse performance at at Dr. H. Soewondo Kendal Regional Hospital. Using a quantitative approach with SEM-PLS and WarpPLS 5.0, data from 110 paramedics (92 nurses and 18 midwives) were analyzed. The results show that interpersonal communication, professionalism, and competence significantly influence the monitoring system (R² = 0.79), which in turn positively affects nurse performance (R² = 0.73). However, competence does not have a significant direct effect on performance without the mediation of the monitoring system. These findings suggest that improving internal factors along with an effective monitoring system can enhance overall paramedic performance and support hospital management in optimizing human resources.
Co-Authors Andi Bunga Dahlia Anindita Paramastuti Azuma Aprilya Sri Rachmayanti Aria Juanda Arie Vonikartika Cindy Octavia Desy Maniarti Gusmali Diani Mega Sari Eka Febriyanti Faziyana Faziyana Ghalib Syukrillah Syahputra Ghiffari, Habibie Deswilyaz Habibie Deswilyaz Henny Rachdianti T S Hesti Marliza Hindyah Ike Suhariati Ibnu Rusyd Lyna Elvira Meddo Lorenza Garnida Mega Sari, Diani Merry Ardini Nelwetis Ni Putu Sugi Maharani Nurlia Oktaviyanti Nurliyasman Nurliyasman Nurul Asiqin Oktasari Oktasari Raden Roro Ratuningrum Anggorodiputro RENI NOVIANTI Reny Haryani Rina Yunita Rury Trisa Utami Selawati Selawati Shinta Sari Dewi Sri Hainil Sri Hainil Suci Fitriani Sammulia Suhaera Suhaera Tommy Julianto Zahara Zahara