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All Journal Agrotrop : Journal on Agriculture Science journal of internal medicine AGRITROP Journal of Agricultural Science and Biotechnology Jurnal Veteriner Bumi Lestari Ecotrophic, Journal of Environmental Science E-Jurnal Agroekoteknologi Tropika (Journal of Tropical Agroecotechnology) Biogenesis: Jurnal Ilmiah Biologi Jurnal Ilmiah Teknologi Pertanian Agrotechno MNJ (Malang Neurology Journal) JURNAL HAMA DAN PENYAKIT TUMBUHAN TROPIKA Agrica: Journal of Sustainable Dryland Agriculture Indonesian Journal of Pharmacology and Therapy
Dewa Ngurah Suprapta
Program Studi Agroekoteknologi Fakultas Pertanian Universitas Udayana
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Energy Environmental Science Immunology & microbiology Medicine & Pharmacology Neuroscience Veterinary

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Efektivitas Rizobakteri untuk Menghambat Pertumbuhan Jamur Collectotrichum acutatum Penyebab Penyakit Antraknosa pada Tanaman Cabai Merah Besar (Capsicum annuum L.) Unedo, Dion; Suprapta, Dewa Ngurah; Suniti, Ni Wayan
Agrotrop : Journal on Agriculture Science Vol 14 No 2 (2024)
Publisher : Fakultas Pertanian Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/AJoAS.2024.v14.i02.p11

Abstract

The Effectiveness of Rhizobacteria to Inhibit the Growth of the Fungus Colletotrichum acutatum that Causes Anthracnose Disease on chili pepper (Capsicum annum L.). Anthracnose in chili pepper caused by the fungus Colletotrichum acutatum is one of the main diseases that affect the production of chili pepper. The use of rhizobacteria as biological agents is considered effective to suppress the spread of anthracnose disease in chili pepper. This study tested the rhizobacteria isolated from the rhizosphere of Graminae and citrus plants to inhibit the growth of the fungus C. acutatum in vitro on PDA media and in vivo on chili peppers. The purpose of this study was to obtain rhizobacteria that could inhibit the growth of fungus C. acutatum, both on PDA media and on chili fruit. The test results showed that the rhizobacteria isolate Yj (isolated from the rhizosphere of citrus plants) could inhibit the growth of the fungus C. acutatum on PDA media by 87.16% compared to the control. In vivo test on chili fruit showed that rhizobacteria isolate Yj could inhibit the growth of C.acutatum fungal colonies by 64.17% when compared to control at 6 days after inoculation.
The potential of polyphenols from natural ingredients against SARS-CoV-2 infection: A review Made Agus Hendrayana; I Made Jawi; Dewa Made Sukrama; Dewa Ngurah Suprapta
Indonesian Journal of Pharmacology and Therapy Vol 2 No 3 (2021): Special Issue: COVID-19
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.2310

Abstract

All countries in the world are facing the coronavirus disease-19 (COVID-19) pandemic which has resulted in various crises. To date, there is no effective treatment in controlling COVID-19. Many clinical trials of approved drugs against COVID-19 were conducted. However, the results were inconclusive, even severe adverse effects were reported. The new effective drugs are therefore urgently needed. Herbal medicines have been widely used by community to enhance the body immune system during COVID-19 pandemic. Polyphenols are large group of active compounds found in the natural ingredients. These compounds have been proven to have biological activity against various pathogen infections including viral infection. During COVID-19 pandemic, various polyphenol compounds from various medicinal plants have been investigated for their activity against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) both in silico and in vitro. Among the polyphenols investigated, some of them namely papyriflavonol, catechin gallate, gallocatechin gallate, luteolin, quercetin, tangeretin, naringenin, herbacetin, emodin, eriodyctiol, fenoterol, baicalin, myricetin, quercetagetin exhibited strong activity against SARS-CoV-2. The possibilities of mechanism of actions as antiSARS-CoV-2 of these polyphenols were 1) bind to the N protein causing the inhibition of viral transcription and replication; 2) inhibit the binding of S protein to ACE2 receptors preventing the entry of the virus into the host cells; 3) inhibit 3CLpro function inhibiting the viral transcription and maturation; and 4) bind directly to the ACE2 receptor. In conclusion, some polyphenol compounds from nature ingredients are potential to develop to be future antiSARS-CoV-2. However, further the pre-clinical and clinical studies are required to strengthen existing evidence.
Co-Authors Agung Bagus S. Satyarsa Agung Wiwiek Indrayan Agus Selamet Duniaji ALPIN JUAN HAGATA PINEM Anak Agung Ngurah Subawa BERTA BR GINTING Emilia Simpllisiu Ake Wangge Gitari, Ni Made Gusti Ngurah Alit Susanta Wirya Hadis Jayanti HENRI PAN BAGUS MULIA NAPITUPULU I B Yoga I Dewa Made Sukrama I G. R. M. TEMAJA I GEDE KARTA SATRIA WIBAWA I Gede Karta Satria Wibawa I Ketut Suada I MADE ADNYANA I Made Jawi I Made Sudana I MADE SUDARMA I Putu Eka Widyadharma I WAYAN GENTA ARIAWAN I Wayan Niryana I Wayan Sumardika Jayanti , Hadis K Agung Sudewa Ketut Suata Khamdan Khalimi Komang Adi Mahartha l MADE SUDARMA LASTRI APRIANI Leana, Ni Wayan Anik Losen Adnyan M. Sudiana Mahendra Made Agus Hendrayana MADE SUSUN PARWANAYONI Meitini Proborini Wahyuni Ni Kadek Desy Andya Dewi NI KOMANG SRI BAWANTARI NI LUH GEDE SRIYANTI NI LUH PUTU SONIA SAVITA DEWI Ni Made Intan Maulina Ni Nyoman Puspawati Ni Putu Ristiati NI WAYAN SUNITI NOVA SULIYANTI SIANTURI Nyoman Darsini PARDIANTA PATRISIUS SINAGA Raka-Sudewi A. A. SANG KETUT SUDIRGA Sanjaya, Feliani Sukmawati Sukmawati Sukmawati Sukmawati Thomas Eko Purwata Unedo, Dion Valente Quintao