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All Journal Jurnal Penelitian Farmasi Indonesia JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Health Sains INDRA: Jurnal Pengabdian kepada Masyarakat Pharmaceutical Sciences and Research (PSR) Jurnal Farmasi Sains dan Praktis Jurnal Pengabdian Masyarakat Medika QISTINA: Jurnal Multidisiplin Indonesia Jurnal Pengabdian Masyarakat Borneo Journal of Pharmacy Journal of Tropical Pharmacy and Chemistry
Adriani Susanty
Sekolah Tinggi Ilmu Farmasi Riau
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In Vitro Cytotoxic Activity Test of Tampa Badak (Voacanga foetida (Blume) Leaves on L1210 Leukemia Susanty, Adriani
JSFK (Jurnal Sains Farmasi & Klinis) Vol 8 No 3 (2021): J Sains Farm Klin 8(3), Desember 2021
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.8.3.323-331.2021

Abstract

The Voacanga foetida (Blume) Rolfe leaves have cytotoxic activity based on our previous research, namely the Brine Shrimps Lethality Test on ethanol extract. This study tested the anticancer activity of the extract and leaf fraction of Voacanga foetida in vitro on L1210 leukemia cells using the direct cell count method and doxorubicin positive control. The results showed that the methanol extract, butanol, ethyl acetate, and hexane fractions, as well as isolated compounds Tb1, Tb2, and Tb3 leaves from Voacanga foetida, had IC50 values of 4.4; 9; 8.4; 16.8; 0.9; 1.8; and 1.1 ppm, compared with doxorubicin with an IC50 value of 0.2 ppm. Based on the IC50 value, it showed that the extract, fraction and isolated compounds of Voacanga foetida had a strong cytotoxic effect, as evidenced by the IC50 value < 30 ppm for each test concentration.
PENANGANAN DAN PENCEGAHAN GAMBARAN DIABETES MELITUS DENGAN MENINGKATKAN TINGKAT PENGETAHUAN MASYARAKAT KOTA PEKANBARU Ulfa, Rodhia; Djohari, Meiriza; Susanty, Adriani; Mora, Enda; Afridho, Arif; Cahyani, Astri; Fitriani, Dewi; Melisa, Eva; Fadhila, Metha; Hasanah, Mitha; Rustam, Muhanifa; Fadhila, Qonita Nur; Sisca, Sari Kurnia
Jurnal Pengabdian Masyarakat Medika Vol 5. No. 1, Maret 2025
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jpmmedika.v5i1.3684

Abstract

ABSTRAK Diabetes melitus (DM) adalah penyakit yang disebabkan gagalnya pankreas memproduksi hormon insulin. Penyakit DM menjadi permasalahan kesehatan yang banyak terjadi di masyarakat Riau. Kegiatan pengabdian ini bertujuan untuk memberikan pemahaman terkait penanganan DM. Metode pelaksanaan kegiatan ini berupa penyuluhan yang didukung dengan adanya pre dan post-test. Kegiatan ini dilaksanakan di kawasan CFD (Car Free Day) Kota Pekanbaru. Alat ukur yang digunakan adalah lembar checklist pre dan post-test serta hasilnya dihitung dengan menggunakan skala Guttmann. Hasil dari kegiatan pengabdian ini adalah sebanyak 30 responden baik laki-laki maupun perempuan mempunyai pemahaman yang sama tentang DM yaitu 82%. Jika dilihat dari segi usia, mayoritas orang dewasa di usia prima memiliki pengetahuan yang lebih tinggi dibandingkan orang yang lebih tua. Mengenai tingkat pendidikan akhir, responden yang berpendidikan tinggi mempunyai pemahaman yang lebih baik (92%). Terkait status pekerjaan, responden yang berstatus bekerja memiliki pengetahuan paling tinggi (84%). Berdasarkan hasil kegiatan terdapat perbedaan yang signifikan antara sebelum dan sesudah kegiatan penyuluhan. Hal ini terlihat dari nilai signifikansi <0,05 (0,000), artinya terdapat perbedaan yang signifikan secara deskriptif antara pre-test dan post-test. Tingkat pengetahuan yang didapatkan adalah rata-rata pengetahuan pre-test (baik) dan post-test (sangat baik). Kesimpulan yang didapat adalah terjadinya peningkatan pengetahuan dari baik menjasi sangat baik.   ABSTRACT Diabetes mellitus (DM) is a disease caused by the failure of the pancreas to produce the hormone insulin. DM is a health problem that occurs in many communities in Riau. This service activity aims to provide an understanding of DM management. The method of implementing this activity is in the form of counseling supported by the pre and post-test. This activity was carried out in the CFD (Car Free Day) area of Pekanbaru City. The measuring instrument used is a pre and post-test checklist sheet and the results are calculated using the Guttmann scale. The results of this service activity are as many as 30 respondents, both men and women, have the same understanding of DM, namely 82%. When viewed in terms of age, the majority of adults in prime age have higher knowledge than older people. Regarding the final level of education, respondents with higher education had a better understanding (92%). Regarding employment status, respondents who were employed had the highest knowledge (84%). Based on the results of the activity, there was a significant difference between before and after the counseling activity. This can be seen from the significance value <0.05 (0.000), meaning that there is a descriptively significant difference between the pre-test and post-test. The level of knowledge obtained is the average knowledge of pre-test (good) and post-test (very good). The conclusion is that there is an increase in knowledge from good to very good.
SOSMED (SOSIALISASI MENCEGAH DIABETES PADA USIA MUDA) Djohari, Meiriza; Susanty, Adriani; Mora, Enda; Ulfa, Rodhia; Putri, Bayzola Ditya; Tania, Berla; Yuti, Denisyah Fitri; Adelina, Helmi Rahmah; Dewi, Irana; Karismawati, Karismawati; Kuang, Liau Che; Achdar, Ridza Fitria; Linda, Rosa; Putri, Widia Rahma
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 5 (2025): BESIRU : Jurnal Pengabdian Masyarakat, Mei 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i5.1152

Abstract

Diabetes melitus (DM) merupakan suatu kelompok penyakit metabolik yang terjadi karena kelainan sekresi insulin, kerja insulin atau kedua-duanya. Kegiatan pengabdian ini bertujuan untuk melihat pengaruh pemberian informasi media leaflet tentang diabetes pada usia muda serta memberikan informasi melalui edukasi terkait penyakit diabetes melitus. Kegiatan pengabdian ini dilakukan dengan metode face to face kepada masyarakat yang ada di Car Free Day (CFD). Responden pada kegiatan penegabdian ini adalah masyarakat yang ada di CFD dengan total responden yaitu 50 orang. Hasil pretest dan post-test menunjukkan peningkatan pengetahuan yang signifikan, dengan p-value 0,000 dari uji Wilcoxon, yang menunjukkan adanya pengaruh positif dari edukasi yang diberikan. 
Chronic Toxicity Study of Ethanol Extract from Voacanga foetida (Blume) Rolfe Leaves on Liver Biochemical and Histopathological Parameters in Male White Rats (Rattus norvegicus) susanty, adriani; Lifiani, Rilialita; Kurniasih, Aminah
JSFK (Jurnal Sains Farmasi & Klinis) Vol 12 No 1 (2025): J Sains Farm Klin 12(1), April 2025
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.12.1.63-71.2025

Abstract

This study aimed to evaluate the chronic toxicity of the ethanol extract of Voacanga foetida (Blume) Rolfe leaves onliver biochemical and histopathological parameters in male white rats (Rattus norvegicus). The animals were orally administeredthe extract daily for six months and divided into four groups: a control group and three treatment groups receiving doses of70, 140, and 210 mg/kg body weight (BW), respectively. Biochemical analyses included serum levels of albumin, total bilirubin, SGOT, SGPT, and triglycerides. Liver histopathological changes were observed both macroscopically and microscopically. The results showed that ethanol extract administration at all tested doses did not cause significant changes (p>0.05) in albumin, total bilirubin, SGOT, or triglyceride levels compared to the control. However, SGPT levels were significantly elevated (p<0.05) in the 140 and 210 mg/kg BW groups. Macroscopic examination revealed no alterations in liver color or texture across all groups. Microscopic observations indicated no structural damage to the central vein in the liver (p>0.05). In conclusion, subchronic oral administration of ethanol extract from V. foetida leaves up to 210 mg/kg BW for six months did not produce significant toxic effects on liver function or morphology in male rats
EDUKASI PANDUAN MINUM OBAT BAGI PENDERITA PENYAKIT DIABETES SAAT BERPUASA Susanty, Adriani; Fernando, Armon; Octavia, Rickha; Arief, Encik Juliansyah; Putri, Dhini Fahira; Safitri, Fasri Dian; Aprilia, Indri; Syafutri, Lidiyah; Aulia, Nada Aqilah; Farisa, Nayla Al; Jannati, Nisa; Ramona, Paula; Mayrade, Salma Yudhistira
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 8 (2025): BESIRU : Jurnal Pengabdian Masyarakat, Agustus 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i8.1769

Abstract

Diabetes mellitus is a chronic disease that poses challenges during Ramadan fasting due to changes in dietary patterns and mediacation schedules. These conditions may increase the risk of hypoglycemia and hyperglycemia, thus requiring proper health education. This community service aimed to improve diabetic patients knowledge regarding medication use during fasting. The methods included lectures, distribution of leaflets, and evaluation using pre-test and post-test questionnaires. The activity was carried  out at Raudhatul Jannah Mosque Pekanbaru, on March 16, 2025, involving 30 participants. The results showed an improvement in participants knowledge, where the “very good” category increased from 13,3% to 40% after the intervention, Statistical analysis using a T-test obtained a p-value of 0,014  indicating a significant difference. This program demonstrated that simple education through counseling and leaflet distribution is effective in enhancing public understanding of proper medication use for diabetic patients during fasting.
Edukasi dan Penyuluhan Diabetes Mellitus Kepada Masyarakat Desa Empat Balai Kecamatan Kuok Kabupaten Kampar Riau Husnawati, Husnawati; Susanty, Adriani; Sari, Seftika; Thamrin, Thamrin; Suheri, Wira Noviana; Izrawati, Izrawati; Delvi, Kasma Muria; Dirmaningsih, Septi; Ngazizah, Yeti Nur; Meridona, Meridona; Sandi, Widya Ari
QISTINA: Jurnal Multidisiplin Indonesia Vol 4, No 1 (2025): June 2025
Publisher : CV. Rayyan Dwi Bharata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57235/qistina.v4i1.6566

Abstract

Diabetes Mellitus (DM) is a non-communicable disease with increasing prevalence, particularly in rural areas with limited access to health information and services. This community service activity aimed to improve the knowledge of residents in Empat Balai Village, Kuok Subdistrict, Kampar Regency, Riau, regarding DM, its risk factors, and prevention efforts through an educational and participatory community-based approach. The method involved direct counseling, group discussions, and pre-test and post-test assessments to evaluate participants' understanding. The results indicated a significant improvement in knowledge, with the average score increasing from 6.7 (pre-test) to 8.98 (post-test). The education program successfully dispelled common myths, raised awareness of healthy lifestyles, and fostered positive perceptions of both medical and non-medical treatment options. The enthusiastic response from the community demonstrated the effectiveness of this approach in promoting health and preventing non-communicable diseases. This activity highlights the importance of collaboration between students, healthcare workers, and local authorities in public health education and the need for sustained outreach programs.
Co-Authors Achdar, Ridza Fitria Adelina, Helmi Rahmah Afridho, Arif Alimin, Nur Arief, Encik Juliansyah Armon Fernando Aulia, Nada Aqilah Cahyani, Astri Dachriyanus Delvi, Kasma Muria Denni Anggraini Desmariani - DEWI FITRIANI Dewi, Citra Kartika Dewi, Irana Dian Sanita Putri Dira Dira Dirmaningsih, Septi Enda Mora Fadhila, Metha Fadhila, Qonita Nur Farisa, Nayla Al Fatma Sri Wahyuni Ferdy Firmansyah Fintolin Jaya Putri Haiyul Fadhli Hasanah, Mitha Husnawati Husnawati Ihsan Ikhtiarudin Indri Aprilia, Indri Ivona Adelin Izrawati, Izrawati Jannati, Nisa Karismawati, Karismawati Kuang, Liau Che Kurniasih, Aminah Lifiani, Rilialita Linda, Rosa Magdazaleni, Magdazaleni Mayrade, Salma Yudhistira Meiriza Djohari, Meiriza Melisa, Eva Melzi Octaviani Meridona, Meridona Mira Febrina Ngazizah, Yeti Nur Nofri Hendri Sandi Nurdina Putri Pedro Anugrah Aswan Putri, Bayzola Ditya Putri, Dhini Fahira Putri, Widia Rahma Ramona, Paula Ratna Sari Dewi Rickha Octavia Rodhia Ulfa Rusnedy, Rahmayati Rustam, Muhanifa Safitri, Fasri Dian Sandi, Widya Ari Sekar, Andisyah Putri Sinata, Novia Sisca, Sari Kurnia Sofia, Sri Esky Syafutri, Lidiyah Tania, Berla Thamrin Thamrin Wewen Sista M Wira Noviana, Wira Noviana Yanwirasti Yanwirasti Yanwirasti Yanwirasti Yuti, Denisyah Fitri