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All Journal HAYATI Journal of Biosciences Jurnal Pengolahan Hasil Perikanan Indonesia FORUM STATISTIKA DAN KOMPUTASI Media Statistika JURNAL KIMIA SAINS DAN APLIKASI Jurnal Manajemen Teknologi CAUCHY: Jurnal Matematika Murni dan Aplikasi Jurnal Ilmu Komputer dan Agri-Informatika The Journal of Pure and Applied Chemistry Research JUITA : Jurnal Informatika Jurnal Aplikasi Bisnis dan Manajemen (JABM) E-Journal Knowledge Engineering and Data Science Jurnal Matematika Sains dan Teknologi Syntax Literate: Jurnal Ilmiah Indonesia Indonesian Journal of Artificial Intelligence and Data Mining BAREKENG: Jurnal Ilmu Matematika dan Terapan Indonesian Journal of Chemistry JTAM (Jurnal Teori dan Aplikasi Matematika) Cetta: Jurnal Ilmu Pendidikan Limits: Journal of Mathematics and Its Applications Martabat: Jurnal Perempuan dan Anak MATRIK : Jurnal Manajemen, Teknik Informatika, dan Rekayasa Komputer Zero : Jurnal Sains, Matematika, dan Terapan Jurnal Ilmiah Ecosystem Jambura Journal of Mathematics Jurnal Samudra Ekonomi dan Bisnis Al-Khwarizmi: Jurnal Pendidikan Matematika dan Ilmu Pengetahuan Alam Inferensi InPrime: Indonesian Journal Of Pure And Applied Mathematics Jurnal Statistika dan Aplikasinya Enthusiastic : International Journal of Applied Statistics and Data Science Xplore: Journal of Statistics Molekul: Jurnal Ilmiah Kimia Indonesian Journal of Jamu Indonesian Journal of Statistics and Its Applications Journal on Mathematics Education Limits: Journal of Mathematics and Its Applications
Utami Dyah Syafitri
Department Of Statistics, Faculty Of Mathematics And Natural Sciences, IPB University, Jl. Meranti Kampus IPB Dramaga, Bogor 16680, Indonesia
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Journal : Molekul: Jurnal Ilmiah Kimia

 1 
Application of Box-Behnken Design for the Extraction of Padina australis Muhammad Nursid; Anissa Permatasari; Utami Dyah Syafitri; Irmanida Batubara
Molekul Vol 17 No 2 (2022)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2022.17.2.6359

Abstract

Optimization extraction of the brown algae Padina australis using the Box-Behnken design has been carried out. Box-Behnken design in relation to Response Surface Methodology analysis was conducted with four experimental factors (i.e., solvent concentration, temperature, extraction time, and sample to solvents ratio) towards the responses of yield antioxidant, anti-tyrosinase, anti-glycation, total phenolic content, and fucoxanthin content, completing with 29 running experiments. P. australis extraction's optimum condition was acquired at 79.99% solvent concentration, 18.48 hours extraction time, 44.50ºC temperature, and 1:9 ratio powders and solvents. The optimum condition provided a 7.30% extraction yield, 43.94% antioxidant activity, 86.83% anti-tyrosinase, 98.06% anti-glycation, 9.53 mg GAE/g total phenolic content, and 347.55 µg/g fucoxanthin content. Respond Surface Methodology analysis with the Box-Behnken design succeeded in making the appropriate model for producing the optimum P. australis extract.
Co-Authors Aam Alamudi Abdul Rohman Abdul Rohman Agus Mohamad Soleh Agustin Faradila Aidi, Muhammad Nur Aji Hamim Wigena Akbar Rizki Alfi Hudatul Karomah ALIU, MUFTIH ALWI Amany, Nurfatimah Anang Kurnia Andrew Donda Munthe Anggrahini, Ervina Dwi Anggraini Sukmawati Anik Djuraidah Anissa Permatasari Antonio Kautsar Anugrah, Cahya Ireno Ardiansyah, M. Ficky Haris ASEP SAEFUDDIN Auliya Ilmiawati Aziza, Vivin Nur Azkiya, Azka Al Baehera, Seta Bagus Sartono Bambang - Riyanto Bambang Prajogo Eko Wardoyo Bambang Riyanto Bartho Sihombing Bayu Pranata, Bayu Budi Susetyo Christin Halim Cici Suhaeni Dea Amelia, Dea Dwi Agustin Nuriani Sirodj Dwi Putri Kurniasari Eka Dewi Pertiwi Eka Winarni Sapitri Eminita, Viarti Endina Fatihah Yasmin Erfiani Erfiani Erfiani, Erfiani Erlinda Widya Widjanarko Ernawati, Fitrah Eti Rohaeti Evita Choiriyah Fadhila Hijryani FAHREZAL ZUBEDI Farit M Afendi Fatimah, Zahra Nurul Fitrianto, Anwar Gandaputra Simbolon, Andreas Nicholas Gusti Tasya Meilania Hari Wijayanto I Made Sumertajaya Idqan Fahmi Immatul Ulya Indahwati Indonesian Journal of Statistics and Its Applications IJSA Intan Lukiswati Irmanida Batubara Irzaman, Irzaman Isti Rochayati Izzati, Mumpuni Nur Joko Santoso Jumansyah, L. M. Risman Dwi Khairil Anwar Notodiputro Kusman Sadik Laradea Marifni Lidiasari, Melisa Lismayani Usman M. Iqbal M. Rafi Meilania, Gusti Tasya Mohamad Rafi Mohamad Rafi Mohamad Rafi Mohammad Masjkur Muhamad Insanu Muhammad Bachri Amran Muhammad Nur Aidi Muhammad Nursid Mulianto Raharjo Muslim, Muhammad Irfai Muthahari, Wadudi Nanik Siti Aminah Nariswari Karina Dewi Ni Kadek Manik Dewantari Noer Endah Islami Nofrida Elly Zendrato Novia Yustika Tri Lestari. YR Nur Aidi, Muhammad Nurhajawarsi Nurhajawarsi Nursifa Mawadah Putri, Thasya R, Arifuddin Rifki Husnul Khuluk Ririn Fara Afriani Riswan Riswan Sanusi, Ratna Nur Mustika Sari, Mutia Dwi Permata Septaningsih, Dewi Anggraini Setyowati, Silfiana Lis Sifa Awalul Fikriah Simbolon, Andreas Nicholas Gandaputra Siwi Haryu Pramesti Soleh, Agus M Soni Yadi Mulyadi Sony Hartono Wijaya Sri Sulastri Sri Wahyuningsih Syam, Ummul Auliyah Syifa Muflihah Tania Amalia Darsono Topan . Ruspayandi Triyani Oktaria Vega, Iliana Patricia Vivin Nur Aziza Weisha, Ghea Wini - Trilaksani Wulan Tri Wahyuni Yenni Angraini Yuan Millafanti Yuni Suci Kurniawati Yuniar Istiqomah