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Colonoscopy and Histopathologic Features in Chronic Diarrhea Patients at Dr. Hasan Sadikin General Hospital, Bandung Rasdianto, Devi Novianto; Nugraha, Eka Surya; Usman, Hermin Aminah; Agustanti, Nenny; Wahyudi, Yudi; Girawan, Dolvy; Bestari, Muhammad Begawan; Abdurachman, Siti Aminah
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 23, No 3 (2022): VOLUME 23, NUMBER 3, December 2022
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2332022188-192

Abstract

Background: Diagnosing and managing patients with chronic diarrhea remains a clinical challenge due to its broad differential diagnoses. Colonoscopy with biopsy is often indicated to establish chronic diarrhea etiologies. However, to date, no data have been published describing the colonoscopic and histological findings in patients with chronic diarrhea at Dr. Hasan Sadikin General Hospital in Bandung. This study aimed to determine the features of colonoscopy and histology in patients with chronic diarrhea.Methods: This study employed a cross-sectional-descriptive design, utilizing secondary data from colonoscopy examinations conducted at Dr. Hasan Sadikin Hospital General Hospital from 2016 to 2019. Participants included adults aged 18 and above who had been diagnosed with chronic diarrhea and had completed both colonoscopy and biopsy procedures.Results: A total of 182 subjects with chronic diarrhea were included in the study. The majority were women (52%), with mean age of 46 years. Upon admission, the predominant clinical presentation was chronic diarrhea without hematochezia, observed in 75% of cases. Meanwhile, 52% of colonoscopy lesions were multiple, with the anal-rectum segment (15%) being the most involved. The most frequent colonoscopic features were hyperemic or edematous lesions, seen in 58% of subjects. The histopathological result from this study revealed that 59% were non-specific chronic colitis (NSCC). Specific histopathological features were primarily found in malignancies and inflammatory bowel disease (IBD) that is 14% 12%, respectively.Conclusion: Chronic diarrhea without hematochezia was the most common objective for referring patients to colonoscopy. The most frequently observed lesion was hyperemic mucosa. Moreover, the NSCC was frequent in histopathological evaluation, followed by malignancies and IBD .
Insidensi Hipoksemia dan Hipotensi pada Cedera Otak Traumatik di RSUP Dr. Hasan Sadikin Bandung Tahun 2015 Arif, Izhar Muhammad; Usman, Hermin Aminah; Bisri, Dewi Yulianti
Jurnal Neuroanestesi Indonesia Vol 6, No 2 (2017)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.792 KB) | DOI: 10.24244/jni.vol6i2.41

Abstract

Latar Belakang dan Tujuan: Cedera otak traumatik (COT) merupakan kasus cedera dengan prevalensi ketiga terbesar diantara cedera bagian tubuh lain (16,8%) di Indonesia. Hipotensi dan hipoksemia adalah prediktor luaran COT yang dapat dikontrol. Penelitian ini bertujuan untuk mengetahui insidensi hipotensi dan hipoksemia pada pasien COT., yang masuk di unit Gawat Darurat Rumah Sakit Dr. Hasan Sadikin.Subjek dan Metode: Penelitian ini berupa deskriptif kuantitatif. Data diambil secara retrospektif dari rekam medis pasien dengan diagnosis COT yang masuk ke Unit Gawat Darurat RSUP Dr. Hasan Sadikin periode 1 Januari 201531 Desember 2015. Sampel diambil secara total sampling, kemudian diklasifikasikan berdasarkan usia, jenis kelamin, etiologi cedera, tingkat COT, saturasi oksigen, dan tekanan darah pasien.Hasil: Didapatkan 669 sampel penelitian. Rata-rata umur sampel adalah 29 tahun dengan jumlah terbanyak di kelompok umur 1524 tahun (30,3%). Kejadian pada laki-laki (71,2%) lebih tinggi dibandingkan perempuan (28,8%). COT paling banyak disebabkan oleh kecelakaan lalulintas (KLL) (68,9%). Terdapat 78 (11,7%) kasus COT berat. Pasien COT yang mengalami hipotensi dan hipoksemia sebanyak 50 orang (7,5%), dan angka kejadian hipotensi dan hipoksemia paling tinggi terdapat pada pasien COT berat (66%). Simpulan: Proporsi kejadian hipoksemia dan hipotensi paling banyak terjadi pada COT berat dengan etiologi KLL.Hypoxaemia and Hypotension Incidence of Traumatic Brain Injury in Dr. Hasan Sadikin Hospital Bandung in 2015Background and Objectives: Traumatic brain injury (TBI) is a case with the third highest prevalence among other injuries (16,8%) in Indonesia. Hypotension and hypoxaemia are TBI outcome predictors which can be controlled. This research aims to find out the incidence of hypotension and hypoxaemia in TBI patients.Subjects and Method: This descriptive quantitative research collected the data retrospectively from the medical record of COT patients who were admitted to Emergency Room (ER) Dr. Hasan Sadikin Public General Hospital in 1 January 31 December 2015. Samples were collected with total sampling technique, and classified based on age, gender, etiology, TBI severity level, oxygen saturation, and blood pressure of the patients.Results: 669 samples were collected. Age average of the samples was 29 years with the highest age group frequency being 15-24 years (30,3%). There were more male patients (71,2%) compared to the female ones (28,8%). The most common cause of TBI was traffic accidents (68,9%). There were 78 (11,7%) severe TBI cases. There were 50 (7,5%) TBI patients with hypoxaemia and hypotension, and the most hypotension and hypoxaemia cases were in severe TBI patients (66%).Conclusion: The proportion of hypoxaemia and hypotension incidence was the highest in severe TBI patients due to traffic accidents.
Clinicopathological Analysis of Rhabdomyosarcoma Patients Undergone Radiotherapy in Two Referral Hospitals in West Java Misuari Sabirin, Muhammad Syah; Usman, Hermin Aminah; Yantisetiasti, Anglita; Sunardi, Mas Adi
Eduvest - Journal of Universal Studies Vol. 4 No. 8 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i8.1307

Abstract

Rhabdomyosarcoma (RMS) is a type of malignant soft tissue neoplasm that develops from mesenchymal cells of skeletal muscle origin. This condition comprises multiple subtypes with distinct histologic characteristics. While cases of RMS are uncommon overall, they are more frequently diagnosed in children, although adults can also be affected. Treatment options for RMS include radiotherapy, with the specific therapy and dosage determined according to the IRS Group classification system. This study was conducted by collecting secondary data of RMS patients from the medical records consecutively who had been diagnosed and received radiotherapy. The data resources were from Radiotherapy Department and Anatomical Pathology Department of RSUP Dr. Hasan Sadikin Bandung and RSUD Al-Ihsan Bandung, between 2017 and 2023. A total of 31 patients were documented. The age of patients ranging from 3 to 66 years old (mean=34.6), with each of age group (children, adult, elderly) consists of 10, 10, and 11 patients respectively. Based on histologic subtype, most cases of RMS recorded are embryonal subtype (n=10) followed by alveolar RMS and pleomorphic RMS with 6 patients each. The extremities were the most common location (n=13) followed by the head and neck region (n=10). After radiotherapy, 20 cases were accounted as radiosensitive and 11 cases were radioresistant. Thirty one patients with rhabdomyosarcoma have received radiotherapy at two referral hospitals in Bandung between 2017-2023. The tumors in pediatric and elderly patients were more sensitive to therapy. Pleomorphic RMS were the most sensitive subtype, and the larger a tumor, the more sensitive it can be.
EFEKTIVITAS MINOSIKLIN SEBAGAI TERAPI AJUVAN PREDNISON UNTUK PENGOBATAN ERITEMA NODOSUM LEPROSUM NEKROTIKANS: SUATU LAPORAN KASUS Rianty, Fathia; Gunawan, Hendra; Usman, Hermin Aminah
Media Dermato-Venereologica Indonesiana Vol 50 No 4 (2023): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v50i4.454

Abstract

Pendahuluan: Manifestasi klinis reaksi kusta tipe 2, selain berupa eritema nodosum leprosum (ENL) klasik, dapat ditemukan bentuk klinis atipikal, salah satunya ENL nekrotikans. Pada reaksi kusta tipe 2 yang berat dan kronis, serta sudah tidak responsif terhadap terapi kortikosteroid tunggal, dapat diberikan minosiklin sebagai terapi ajuvan. Tujuan laporan kasus ini untuk menunjukkan efektivitas minosiklin sebagai terapi ajuvan prednison untuk pengobatan ENL nekrotikans. Kasus: Dilaporkan satu kasus kusta tipe borderline lepromatous disertai ENL nekrotikans pada seorang laki-laki berusia 23 tahun. Berdasarkan anamnesis diketahui pasien telah mengalami ENL berat lebih dari enam bulan dan tidak membaik dengan terapi kortikosteroid tunggal. Pada pemeriksaan fisis ditemukan ulkus multipel yang nyeri, dengan tepi meninggi, disertai black eschars di lengan dan tungkai. Gambaran histopatologis menunjukkan ulserasi epidermis, nekrosis di dermis, disertai gambaran vaskulitis leukositoklastik, infiltrat sel radang, dan panikulitis, yang menunjang diagnosis ENL nekrotikans. Pasien mendapat multidrug therapy-multibacillary, serta kombinasi prednison dan minosiklin 100 mg/hari. Perbaikan klinis terjadi setelah pengobatan bulan pertama. Diskusi: Lesi kulit awal ENL nekrotikans berupa plak atau nodul eritem, kemudian menjadi ulkus yang dalam dan nyeri, disertai black eschar. Minosiklin, selain memiliki efek anti-inflamasi, juga memiliki efek neuroprotektif dan sifat imunomodulasi, sehingga dapat digunakan dalam pengobatan reaksi kusta. Pada kasus ini, setelah enam bulan tidak berespons terhadap terapi prednison tunggal, terjadi perbaikan klinis setelah satu bulan mengonsumsi terapi kombinasi prednison dan minosiklin. Kesimpulan: Minosiklin efektif sebagai terapi ajuvan prednison untuk pengobatan ENL nekrotikans.
Co-Authors . Afiati, . Abdul Hadi Hassan, Abdul Hadi Afiati Afiati Afiati Afiati Ahmad Faried Anglita Yantisetiasti Anjani, Gebby Reviana Apriliani, Ardhia Rizki Arif, Izhar Muhammad Arif, Izhar Muhammad Arima Kurnia Sari Dewi Nurcahyani Astrid Feinisa Khairani Atika Hana Ilyasa Bashari, Muhammad Hasan Bethy Surjawathy Hernowo Bethy Surjawathy Hernowo Bethy Suryawathy Hernowo Billy Parulian Lubis Defi Ardia Pramesti Dewayani, Birgitta Maria Dewi Yulianti Bisri Dika Widia Nur Azizah Dimas Erlangga Luftimas Dimas Erlangga Luftimas Dolvy Girawan Dwi Andini Edward Jaya Hadi Egie Rahmalaelani Eka Surya Nugraha Erida, Yulie Fauzan Ali Zainal Abidin Gian Nugraha Gurwinder Kaur a/p Gurcharan Singh Gurwinder Kaur a/p Gurcharan Singh Hasrayanti Agustina Hasrayati Agustina HENDRA GUNAWAN B11211055 Hendrikus Bolly Herry Yulianti Jessica Oktavianus Trisaputra Jono Hadi Agusni Jono Hadi Agusni, Jono Hadi Khafifah, Dinda Salsa Labibah, Salma Nur Lala Yuliani Laraswita, Sarah Meinarni, Retno Misuari Sabirin, Muhammad Syah Muhammad Begawan Bestari Nadiah, Zahra Nadifah Diana Zalia Naura Mardhiyah Nenny Agustanti Nita Novita Noor Fitriana, Maya Novi Vicahyani Utami Nugraha, Marwan Agung Nurhasanah Nurhasanah Nurhidayat, Ade Apon Putri Halleyana Rahmalaelani, Egie Rahman, Putri Halleyana A Ramdhani, Muhammad Farid Rani Septriana Rani Septrina Rania Azzahra Salsazayasya Parikesit Rasdianto, Devi Novianto Reti Hindritiani Rianty, Fathia Rika Mustika Risqi Dwi Putra Sholihah, Fitria Siska Dwiyantie Wahyuni Siti Aminah Abdurachman Sri Suryanti Sunardi, Mas Adi Titing Nurhayati Trisaputra, Jessica Oktavianus Yudi Wahyudi Yunnica Yunnica Zahra Nurusshofa