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All Journal Majalah Obat Tradisional Jurnal SOLMA Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Dunia Farmasi Jurnal Ilmu Kesehatan Jurnal Kefarmasian AKFARINDO Best Journal (Biology Education, Sains and Technology) HERBAPHARMA : Journal of Herb Farmacological Jurnal Farmagazine Borneo Journal Of Pharmascientech Tunas Medika Jurnal Kedokteran & Kesehatan Quimica : Jurnal Kimia Sains dan Terapan Jurnal Insan Farmasi Indonesia Journal of Fundamental and Applied Pharmaceutical Science Jurnal EduHealth Jurnal Ilmiah Bakti Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Sains dan Praktis Jurnal Sehat Indonesia (JUSINDO) Ekalaya: Jurnal Pengabdian Kepada Masyarakat Indonesia Jurnal Lentera Pengabdian Journal Of Medicine And Health Sciences (Medisci) Journal of Community Service (Abdisci) Medical Sains : Jurnal Ilmiah Kefarmasian
Putra, Teguh Adiyas
Program Studi Farmasi, STIKes Muhammadiyah Cirebon
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Profil Senyawa Fitokimia Menggunakan Metode FTIR dan Pengujian Nilai SPF Secara In Vitro Formulasi Lotion O/W Ekstrak Etanol 96% Daun Binahong Hijau Nurluthfiana, Deby; Adiyas Putra, Teguh; Irawan, Ade
BORNEO JOURNAL OF PHARMASCIENTECH Vol 9 No 1 (2025): Borneo Journal Of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59053/bjp.v9i1.546

Abstract

The 96% ethanol extract of green binahong leaves contains flavonoid compounds with potential activity as a sunscreen. Flavonoid compounds have been identified via FTIR and show part of this functional group. in the form of aliphatic C-H, C=O, C=C, and C-O. This research aims to determine the stability of the physical and chemical quality of o/w type sunscreen lotion and its activity as a sunscreen in vitro using a UV-vis spectrophotometer. The extract is obtained using the ethanol maceration method and then formulated into lotion and o/w cream and tested for physical and chemical stability and tested for SPF in vitro with a spectrophotometer. The results of this research indicate that the o/w lotion formula is stable during the storage period of 6 cycles. The increase in the diameter value of spreadability and sticking time is influenced by storage factors, the longer the preparation is stored, the viscosity will decrease. Sunscreen activity calculated using the Mansur equation shows that the SPF value at 0.5%, 2.5% and 4.5% levels of green binahong leaf extract is 3.37; 8.25 ; 8.93. The sunscreen lotion preparation of 96% ethanol extract of green binahong leaves is stable during storage and has activity as a sunscreen.
PELATIHAN PEMBUATAN NUGGET N-MUSROOM SEBAGAI ALTERNATIF MAKANAN SEHAT IBU-IBU PKK DESA PATALAGAN KABUPATEN KUNINGAN Efriani, Like; Putra, Teguh Adiyas; Gunawan, Ucha Indra
Ekalaya: Jurnal Pengabdian Kepada Masyarakat Indonesia Vol. 2 No. 3 (2023): Ekalaya Journal
Publisher : Nindikayla Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57254/eka.v2i3.105

Abstract

Patalagan Village has various types of plants that are diverse and efficacious and can be used as home preparations that can be utilized as a source of food production and so on and can also be marketed to various regions. One of the superior potentials that can be utilized by the community as a source of income is oyster mushrooms. The purpose of this community service is to increase the knowledge of Patalagan Village residents regarding the benefits of oyster mushrooms and improve the skills of housewives in making nuggets from oyster mushrooms. The materials used are oyster mushrooms, while the methods used are socialization and counseling as well as training in making N-mushroom nuggets and product making demonstrations carried out by PKK women in Patalagan Village. The result of this training was that the participants became trained in making N-mushroom nuggets. This can be seen from the products produced by participants with good results in terms of appearance. The conclusion is that there is an increase in villagers' knowledge of the benefits of oyster mushrooms as can be seen from the results of the pretest and posttest activities given to participants where there is an increase in scores before and after the counseling and the PKK women of Patalagan Village are skilled in making "N-mushroom nuggets" products which can be seen from the quality of the products produced.
Pelatihan Pembuatan Minyak Sobat (Minyak Gosok Herbal) di Desa Sarewu, Kecamatan Pancalang, Kabupaten Kuningan Ulfah, Mariam; Irawan, Ade; Putra, Teguh Adiyas
Jurnal SOLMA Vol. 14 No. 2 (2025)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v14i2.15556

Abstract

Background: Minyak gosok yang mengandung minyak atsiri serai memiliki keunggulan karena disamping mendapatkan manfaat dari minyak gosok yaitu meredakan nyeri otot dan sendi, pusing, masuk angin, keseleo, mual dan melegakan pernafasan juga mendapatkan manfaat dari kandungan minyak atsiri serai seperti antioksidan, antibakteri dan antijamur. Adapun tujuan dari program pengabdian ini yaitu meningkatkan kesadaran warga desa akan manfaat minyak atsiri sereh dan minyak gosok herbal, melatih ibu-ibu untuk membuat alat destilasi sederhana dengan menggunakan alat-alat yang ada di rumah untuk mendapatkan minyak atsiri serai, serta melatih ibu-ibu untuk membuat minyak gosok herbal (SOBAT). Metode: Mitra dalam kegiatan ini adalah ibu-ibu rumah tangga desa Sarewu dengan jumlah peserta sebanyak 15 orang. Metode pengabdian terbagi ke dalam tiga tahapan utama yaitu persiapan, pelaksanaan dan evaluasi. Hasil: Hasil kegiatan pengabdian ini adalah ibu-ibu rumah tangga dapat merangkai alat destilasi sederhana dengan memanfaatkan alat-alat di dapur, ibu-ibu rumah tangga dapat membuat minyak SOBAT dan naiknya kesadaran  ibu-ibu rumah tangga Desa Sarewu akan manfaat kesehatan sereh bagi kesehatan. Hal ini terlihat perubahan signifikan pada kategori sangat setuju dari yang sebelumnya tidak ada responden yang menyatakan sangat setuju akan manfaat kesehatan serai (0%)  menjadi 7 orang (46,7%) responden yang menyatakan setuju akan manfaat kesehatan serai. Kesimpulan: Kesimpulan  dalam pengabdian ini adalah meningkatnya kesadaran mitra akan manfaat kesehatan minyak atsiri sereh dan minyak gosok herbal, mitra menjadi terlatih dalam membuat alat destilasi sederhana untuk mendapatkan minyak atsiri serai dan dalam pembuatan minyak SOBAT.
Formulation and evaluation of lip balm preparations of ethanolic extract from beetroot (Beta vulgaris L.) Hadi, Ismanurrahman; Shinta, Tiara Aries; Putra, Teguh Adiyas
Journal of Fundamental and Applied Pharmaceutical Science Vol. 6 No. 1 (2025): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v6i1.19331

Abstract

Beetroot (Beta vulgaris L.) is a source of betacyanin that could be used as a natural dye and is known as an antioxidant that can protect the skin from exposure to free radicals. Lip balm, one of the popular cosmetics, often uses natural ingredients as active compounds to enhance colour and promote healthy skin. This study aims to formulate beetroot ethanolic extract into a topical lip balm preparation. The beetroot was extracted using ethanol solvent. The phytochemical screening was carried out to identify phytochemicals of flavonoids, saponins, tannins, and alkaloids within the ethanolic extract. The extract was formulated into a lip balm preparation with extract concentrations of 0% (F1), 5% (F2), 10% (F3), and 15% (F4). After formulation, the lip balm was physically examined for organoleptic, homogeneity, acidity, spreadability, and adhesivity of the product. The phytochemical screening exhibited positive results in all phytochemical groups tested in the beetroot ethanolic extract. Meanwhile, physical evaluation of lip balm demonstrates that all formulations had a semi-solid texture, cacao scent, and red color that increased in intensity proportionate with the extracts used (F2, F3, F4). Other parameters indicate a homogeneous product with suitable acidity (pH valued at 9) and adhesivity (>4 seconds). However, the spreadability test displayed low dispersion capabilities of the lip balm. Even though the spreadability values increased with higher beetroot extract, this value remained lower than the standard minimum dispersion of lip balm, thus indicating poor spreadability of the formula. The hedonic evaluation indicates that respondents tended to like the third formulation (F3). Based on this, the best and most preferred formula is at a concentration of 10% active substance (F3).
Analisis Interaksi Obat Antipsikotik pada Pasien Bipolar di Rumah Sakit Jiwa Provinsi Jawa Barat Periode Januari-Desember 2023 Efriani, Like; Putra, Teguh Adiyas; Fauzia, Hilda Nurul
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 1 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v7i01.178

Abstract

Bipolar merupakan gangguan mental yang ditandai dengan perubahan suasana hati yang drastis antara episode manik dan depresi. Penelitian ini bertujuan untuk menganalisis interaksi obat berdasarkan tingkat keparahan dan mekanisme interaksi obat yang terjadi pada pasien bipolar di Rumah Sakit Jiwa Provinsi Jawa Barat. Penelitian ini menggunakan desain cross-sectional (potong lintang) dengan metode retrospektif. Populasi penelitian adalah seluruh pasien di instalasi rawat jalan dengan diagnosis bipolar pada tahun 2023 sebanyak 299 pasien, dan sampel sebanyak 171 pasien dipilih menggunakan teknik purposive sampling. Data dikumpulkan melalui rekam medis pasien, mencakup informasi demografis, riwayat penggunaan obat antipsikotik, dan kejadian interaksi obat. Hasil penelitian menunjukkan bahwa interaksi obat farmakodinamik lebih banyak terjadi (87,7%) dibandingkan dengan farmakokinetik (12,3%). Kombinasi obat yang paling sering digunakan adalah risperidone-trihexyphenidyl dengan tingkat keparahan moderat. Kesimpulannya, interaksi farmakodinamik merupakan jenis interaksi yang paling umum terjadi, dengan tingkat keparahan moderat sebagai yang paling sering ditemukan. Pemantauan ketat dan penyesuaian dosis diperlukan untuk mengurangi risiko interaksi yang berbahaya pada pasien bipolar.
Potential of Several Phytochemicals of Mangrove Species (Rhizopora stylosa) as Inhibitor of Both Viral Gene Expression and Bacterial Nucleic Acid Synthesis Hadi, Ismanurrahman; Irawan, Ade; Ulfah, Mariam; Putra, Teguh Adiyas; Efriani, Like; Haq, Mailatul Ilal; Purnama, Muhamad Rifki
Jurnal Ilmu Kesehatan Vol 10 No 1 (2022): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v10i1.3278

Abstract

The mangrove family (Rhizophora stylosa) has been used as traditional medicine. Due to the habitat of mangroves, they develop unique phytochemicals. Thus, they have the potential to become a source of plant-based therapeutic agents. However, many of the them remain uninvestigated. The purpose of this study was to predict the potential of some phytochemicals of the mangrove family as an inhibitor of both viral gene expression and bacterial nucleic acid. Some bioactive compounds of mangrove (taraxerol, pyrethrin, 2-Furancarboxaldehyde, and avicequinone A) were used as subject of this study. The main protease (Mpro) of SARS-Cov-2 virus (PDB ID: 6y2e), the staphylococcus aureus's proteins: topoisomerase II DNA gyrase (PDB id: 2XCT), and tyrosyl-tRNA synthetase (PDB id: 1JIJ) were used as targeted protein. The drug-likeness of compounds were analyzed using Swiss ADME based on the Lipinsky rule of five. Meanwhile, the affinity value between proteins and ligands was predicted using Autodock Vina. The root means square distance (RMSD) value (<2 A) and the binding cavity of drugs (ivermectin and ciprofloxacin) were used as validation parameters. This study resulted that only taraxerol compounds have a violation of Lipinsky's rule. Even so, out of the phytochemical compound of mangrove, the taraxerol has the highest affinity in Mpro and topoisomerase II DNA gyrase protein, although still lesser than ivermectin against Mpro; while avicequinone A has the highest affinity against tyrosyl-tRNA synthetase. This concludes that some phytochemicals of the mangrove family could be developed as an antibacterial and antiviral agents of therapy.
Evaluation Of The Rationality Of The Use Of Anemia Drugs In Anemia Patients In Rsd Gunung Jati Cirebon City For The Period January-December 2022 Miftahul Janah; Like Efriani; Teguh Adiyas Putra
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Anemia is a condition where the hemoglobin (Hb) level in the blood is less than normal levels. The aim of this research is to determine the characteristics of anemia patients in the inpatient installation at RSD Gunung Jati, Cirebon City, to find out the prescribing of anemia at RSD Gunung Jati, Cirebon City for the period January- December 2022 and to determine the rationality evaluation of the use of anemia medication at RSD Gunung Jati, Cirebon City on an appropriate basis. indication, correct diagnosis, right drug and right dose. This study used a retrospective research design. The rationality analysis was carried out using a purposive sampling method. The data taken is medical record data and patient prescriptions to see the rationality of treatment. The number of samples in this study was 73 samples which met the inclusion criteria. The statistical analysis used in this research is chi-square and Mann-Whitney. The parameters used in the research are the correct indication, correct diagnosis, correct drug and correct dose. The results of the study showed that anemia was mostly experienced by women as many as 37 patients (51%) and elderly people (46-65 years) as many as 40 patients (55%) with elementary school education levels as many as 35 patients (48%). The anemia drugs most commonly used by anemia patients in patient installations at RSD Gunung Jati, Cirebon City for the period January-December 2022 are multivitamins, haemostatics, neurotropic vitamins and iron preparations, respectively. The evaluation results showed that the indication was 100% correct, the diagnosis was 100% correct, the drug was 100% correct and the dose was 95% correct. The statistical test results showed that the use of anemia drugs in anemia patients met the rational requirements and had a significant rationality value.
Aktivitas Antijamur Ekstrak Aseton Daun Teratai Putih (Nymphae alba) Terhadap Jamur Candida albicans Irawan, Ade; Ulfah, Mariam; Putra, Teguh Adiyas
BEST Journal (Biology Education, Sains and Technology) Vol 6, No 2 (2023): September 2023
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v6i2.8210

Abstract

Indonesia is a tropical country with very diverse plants. This plant is a source of secondary metabolite compounds that have pharmacological activities that combine a variety of them including antifungal. One of them is the white lotus (Nymphae alba). This plant contains flavonoids, phenols, terpenoids and alkaloids. This plant also has pharmacological activities including antioxidant, antiobesity, analgesic and antidiarrheal. This study aims to determine the inhibition zone of white lotus acetone extract (N.alba) against the fungus Candida albicans. The extraction process was carried out by maceration method with acetone solvent for 3 x 24 hours. The antifungal test method was carried out using the disc diffusion method, three concentrations of acetone extract were used, 25%, 50% and 75%, the positive control used was ketoconazole and the negative control was 10% DMSO. The results of this study were white lotus acetone extract which had an inhibition zone value of 11.8 mm for the extract with a concentration of 25% in the strong category, 14 mm for the extract with a concentration of 50% in the strong category, and 16.3 mm for the extract with a concentration of 75 % in the strong category, while the positive control has an inhibition zone value of 10 mm. This proves that white lotus has good potential as an antifungal agent from plant. 
Uji Aktivitas Antibakteri Ekstrak Umbi Porang (Ammorphophallus muelleri Blume) Pada Streptococcus pyogenes, Propionibacterium acnes, Pseudomonas aeruginosa dan Escherichia coli Putra, Teguh Adiyas; Ulfa, Mariam; Tiany, Ratu Faradhifa Ananda
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 2 (2025): September 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i2.12769

Abstract

 Penelitain ini bertujuan untuk menetahui aktivitas antibakteri ekstrak etanol umbi porang (Amorphophallus muelleri Blume) terhadap bakteri Streptococcus pyogenes, Propionibacterium acnes, Pseudomonas aeruginosa dan Escherichia coli serta untuk mengetahui kandungan senyawa metabolit sekunder pada tanaman porang (Amorphophallus muelleri Blume). Ekstrak dibuat dengan menggunakan metode maserasi menggunakan etanol 96% selama 3x24 jam. Uji aktivitas antibakteri menggunakan metode difusi cakram dengan menggunakan variasi konsentrasi ekstrak umbi porang (Amorphophallus muelleri Blume) yaitu 10%, 15%, 20%, dan 25%, dan dilakukan skrining senyawa metabolit sekunder menggunakan uji tabung dan pengujian Kromatografi Lapis Tipis (KLT), dan Fourier Transform Infrared (FTIR) . Hasil yang diperoleh menunjukan bahwa ekstrak umbi porang (Amorphophallus muelleri Blume) memiliki aktvitas antibakteri terbesar pada konsentrasi 25% dengan hasil rata-rata diameter pada tiap bakteri uji  10,01 mm dan diamaeter zona hambat terendah menunjukan nilai rata rata 6,16 mm, serta positif mengandung senyawa alkaloid, flavonoid, dan saponin. Hasil analisis data menggunakan SPSS menunjukan hasil data yang terdistribusi normal dan homogen dengan hasil p0,05, dan data menunjukan hasil p0,05 pada uji ANOVA yang menunjukan adanya perbedaan yang signifikan pada variasi konsentrasi, sehingga ekstrak umbi porang berpotensi dikembangkan sebagai agen antibakteri alami.
ANALISIS INTERAKSI OBAT PADA PASIEN DISPEPSIA DENGAN PENYAKIT PENYERTA DI INSTALASI RAWAT INAP DI RUMAH SAKIT X KABUPATEN MAJALENGKA TAHUN  2024 Yulianti, Tia; Ade Irawan; Putra, Teguh Adiyas
Jurnal Insan Farmasi Indonesia Vol 8 No 2 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/weamq732

Abstract

Dyspepsia is common digestive disorder that can significantly impact a patient's quality of life, particularly in individuals with comorbid conditions. Lifestyle factors, stress, and the use of various medications can contribute the onset of symptoms. One important aspect to consider is drug interactions, especially in elderly patients undergoing polypharmacy. This study aims to analyze drug usage patterns and identify potential drug interactions in patients diagnosed with dyspepsia and comorbidities. The research employed a non-experimental observational design using a retrospective descriptive method. Data were collected from inpatient medical records at Hospital X in Majalengka Regency, involving patients diagnosed with dyspepsia and accompanying illnesses. The profile dyspepsia patients with comorbidities in the inpatient unit of Majalengka Regional Hospital in 2024 was: the highest number patients were aged 46-55 years (24 patients, or 29%), and the highest number of patients were female (63 patients, or 78%). The most common single drug used for dyspepsia was ranitidine (14 cases, 87.50%). The most common two-drug combination was ranitidine and sucralfate (9 cases, 25.00%), and the most common three-drug combination was sucralfate + ranitidine + domperidone (12 cases, 37.50%). Drug interactions, based on severity, were classified as minor (32 cases, 96.97%), and moderate (1 case, 3.03%).
Co-Authors Ade Irawan Ade Irawan Ade Irawan Ade Irawan Angeline Safitri, Karin Arif Setiawansyah Arofah Firda Rahmah Ayu Puspitasari, Ayu Ayu Syarifah, Nyimas Az-zahra, Hasna Zaqiyah Bisam, Zahra Azizah Nursetya Citra Ariani Citra Tasya Ulwia Dewi Luthfiana Efriani, Like Eka Ratnasari Elfasyari, Trie Yuni Epiyawati, Devi Ersi Arviana Ihsan Euis Nurkholifah Mahendra Fauzia, Hilda Nurul Fika Nurul Hidayah Gunawan, Ucha Indra Hadi, Ismanurrahman Hanifah Karimatulhajj Haq, Mailatul Ilal Hidayah, Fika Nurul Ismayanti Istanto Kamila, Risa Chahya Kintoko, Kintoko Like Efriani Lina, Indri Afni Enjel MARIAM ULFA, MARIAM Mariam Ulfah MARIAM ULFAH ULFAH Marnisa B., Fiiryal Miftahul Janah Nadzar Darmawan, Muhamad Nesta Nesta, Nesta Nurhasanah Nurkhasanah Nurkhasanah Nurlutfia, Deby Nurluthfiana, Deby Nursidik, Ahmad Perdana Priya Haresmita Permatasari, Nova Purnama, Muhamad Rifki Puspawan Hariadi Putri, Ghefira Aulia Rahmatika, Siti Difta Reza Alrayan Rizki, Kiki Nur Rizky Putri Ramadhan Safitri, Karin Angeline Shalsalbillah, Maharani Hafifa Sherly Marshelia Shinta, Tiara Aries Taruna, Riyan Tia Yulianti Tiany, Ratu Faradhifa Ananda Ulfah, Mariam Yulia Rosdiana Dewi Zahra Azizah Nursetya Bisam