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Uji Aktivitas Antibakteri Ekstrak Umbi Porang (Ammorphophallus muelleri Blume) Pada Streptococcus pyogenes, Propionibacterium acnes, Pseudomonas aeruginosa dan Escherichia coli Putra, Teguh Adiyas; Ulfa, Mariam; Tiany, Ratu Faradhifa Ananda
BEST Journal (Biology Education, Sains and Technology) Vol 8, No 2 (2025): September 2025
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v8i2.12769

Abstract

 Penelitain ini bertujuan untuk menetahui aktivitas antibakteri ekstrak etanol umbi porang (Amorphophallus muelleri Blume) terhadap bakteri Streptococcus pyogenes, Propionibacterium acnes, Pseudomonas aeruginosa dan Escherichia coli serta untuk mengetahui kandungan senyawa metabolit sekunder pada tanaman porang (Amorphophallus muelleri Blume). Ekstrak dibuat dengan menggunakan metode maserasi menggunakan etanol 96% selama 3x24 jam. Uji aktivitas antibakteri menggunakan metode difusi cakram dengan menggunakan variasi konsentrasi ekstrak umbi porang (Amorphophallus muelleri Blume) yaitu 10%, 15%, 20%, dan 25%, dan dilakukan skrining senyawa metabolit sekunder menggunakan uji tabung dan pengujian Kromatografi Lapis Tipis (KLT), dan Fourier Transform Infrared (FTIR) . Hasil yang diperoleh menunjukan bahwa ekstrak umbi porang (Amorphophallus muelleri Blume) memiliki aktvitas antibakteri terbesar pada konsentrasi 25% dengan hasil rata-rata diameter pada tiap bakteri uji  10,01 mm dan diamaeter zona hambat terendah menunjukan nilai rata rata 6,16 mm, serta positif mengandung senyawa alkaloid, flavonoid, dan saponin. Hasil analisis data menggunakan SPSS menunjukan hasil data yang terdistribusi normal dan homogen dengan hasil p0,05, dan data menunjukan hasil p0,05 pada uji ANOVA yang menunjukan adanya perbedaan yang signifikan pada variasi konsentrasi, sehingga ekstrak umbi porang berpotensi dikembangkan sebagai agen antibakteri alami.
ANALISIS INTERAKSI OBAT PADA PASIEN DISPEPSIA DENGAN PENYAKIT PENYERTA DI INSTALASI RAWAT INAP DI RUMAH SAKIT X KABUPATEN MAJALENGKA TAHUN  2024 Yulianti, Tia; Ade Irawan; Putra, Teguh Adiyas
Jurnal Insan Farmasi Indonesia Vol 8 No 2 (2025): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/weamq732

Abstract

Dyspepsia is common digestive disorder that can significantly impact a patient's quality of life, particularly in individuals with comorbid conditions. Lifestyle factors, stress, and the use of various medications can contribute the onset of symptoms. One important aspect to consider is drug interactions, especially in elderly patients undergoing polypharmacy. This study aims to analyze drug usage patterns and identify potential drug interactions in patients diagnosed with dyspepsia and comorbidities. The research employed a non-experimental observational design using a retrospective descriptive method. Data were collected from inpatient medical records at Hospital X in Majalengka Regency, involving patients diagnosed with dyspepsia and accompanying illnesses. The profile dyspepsia patients with comorbidities in the inpatient unit of Majalengka Regional Hospital in 2024 was: the highest number patients were aged 46-55 years (24 patients, or 29%), and the highest number of patients were female (63 patients, or 78%). The most common single drug used for dyspepsia was ranitidine (14 cases, 87.50%). The most common two-drug combination was ranitidine and sucralfate (9 cases, 25.00%), and the most common three-drug combination was sucralfate + ranitidine + domperidone (12 cases, 37.50%). Drug interactions, based on severity, were classified as minor (32 cases, 96.97%), and moderate (1 case, 3.03%).
Human Immunodeficiency Virus (HIV): Epidemiology, Prevention, and Management Challenges in Indonesia Irawan, Ade; Putra, Teguh Adiyas
Jurnal Medisci Vol 2 No 5 (2025): Vol 2 No 5 April 2025
Publisher : Ann Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62885/medisci.v2i5.1002

Abstract

Background. Human Immunodeficiency Virus (HIV) is one of the global public health problems that is still a serious challenge, including in Indonesia. HIV infection causes a decrease in the immune system, which leads to Acquired Immunodeficiency Syndrome (AIDS) if not treated appropriately. Purpose. This article aims to examine the development of HIV epidemiology, risk factors for transmission, prevention strategies, and HIV management efforts in Indonesia, based on a recent scientific literature review. Method. The method used is a literature study of relevant national and international journal articles. Results. The results of the study show that the increase in HIV cases is influenced by risky behaviors, low access to tests and therapies, and stigma and discrimination against People With HIV/AIDS (ODHA). Prevention efforts through HIV education, testing, and counseling, and antiretroviral therapy (ARV) have proven effective in reducing the rate of transmission. Conclusion. In conclusion, HIV control requires a multidisciplinary approach that involves medical, social, and health policy aspects.