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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Klinik Indonesia MNJ (Malang Neurology Journal) The Indonesian Biomedical Journal Majalah Kesehatan FKUB JSFK (Jurnal Sains Farmasi & Klinis) JFL : Jurnal Farmasi Lampung Jurnal Kefarmasian AKFARINDO ADMA: Jurnal Pengabdian dan Pemberdayaan Masyarakat Universitas Muhammadiyah Yogyakarta Undergraduate Conference Proceeding Prosiding Seminar Nasional Program Pengabdian Masyarakat Jurnal Info Kesehatan
Aris Widayati
Faculty of Medicine, Universitas Brawijaya
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Edukasi Hidup Sehat Untuk Mengatasi Masalah Kesehatan Remaja Syuja, Najmie Muhammad; Permana, Mohammad Rafli; Putri, Andhini Eka; Rifqiyah, Iffatur; Ziv, Khansa Fikriyah; Sukoco, Naura Hasyifa Anindya; Zakwan, Hazy Rizali; Affan, Muhammad; Rahayu, Safira Sri; ‘Azhim, Muhammad Fauzan; Widayati, Aris
Prosiding Seminar Nasional Program Pengabdian Masyarakat Vol. 8 No. 1 (2025): Rekonstruksi Pendidikan di Indonesia
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/ppm.81.1274

Abstract

Community service is a form of implementation of the Tri Dharma of Higher Education, which emphasizes community service. Community service can be carried out in various forms of activities and assistance. The community service program carried out in Kalidadap 1 Hamlet, Selopamioro Village, Imogiri District, Bantul focuses on empowering adolescent health. The observation results show problems related to the lack of attention to adolescent health. Therefore, the purpose of this program is to increase the knowledge and awareness of adolescents in Kalidadap 1 Hamlet, so that they can foster an attitude of concern for their health. The method used in this activity is an educational approach that includes a series of integrated activities, namely counseling on reproductive health, balanced nutrition, prevention of anemia, training of adolescent health cadres, family care, and counseling on Clean and Healthy Living Behavior (PHBS). Community service is a form of implementation of Tri Dharma Perguruan. The results of the implemented program showed an increase in knowledge, skills, and awareness of adolescents towards health through education on anemia prevention, the dangers of promiscuity, the importance of balanced nutrition, and reproductive health. In addition, this activity also had a positive impact on improving the skills of health cadres in measuring hemoglobin and providing education on anemia prevention. Thus, this service program is expected to have a positive impact in the long term and can help the community in creating a healthier, smarter, more productive, and competitive younger generation in Kalidadap 1 Hamlet.
Efektivitas Monitoring Kesehatan Pasien Pengidap Penyakit Tidak Menular di Kajor Kulon Selopamioro Imogiri Bantul Harahap, Feby Nur Alyani; Yebi, Saffana Racho Mauluda; Pradhana, Muhamad Ilham Satya; Rifa’i, Putri Fadia; Alfiani, Dhea Fita; Muna, Wildan Syithrul; Ayu, Yuniarti Mega; Putri, Zahra Saphira; Prayata, Kenzie Wistara; Fahrezy, Ergi Ahmad; Widayati, Aris
Prosiding Seminar Nasional Program Pengabdian Masyarakat Vol. 8 No. 1 (2025): Rekonstruksi Pendidikan di Indonesia
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/ppm.81.1276

Abstract

Non-communicable diseases (NCDs) are the leading cause of death globally, with 41 million deaths each year. Non-communicable diseases are caused by a combination of modifiable and non- modifiable risk factors, including modern lifestyles that influence diet and smoking habits. In Kajor Kulon, Selopamioro, Imogiri, Bantul, D.I.Yogyakarta, people tend to practice unhealthy lifestyles such as consumption of foods high in sugar, salt and saturated fat, which contribute to the high prevalence of non-communicable diseases, including hypertension and diabetes. Therefore, this community service program aims to increase community awareness of NCDs through socialisation, screening, and health monitoring. The activity was conducted in February 2025, involving 75 high-risk and elderly participants. The method used in this approach was socialisation with material presentation on hypertension, followed by free health screening that included blood pressure, blood sugar, and cholesterol checks. Monitoring was conducted periodically for four families with NCDs. Monitoring results showed a decrease in blood pressure in participants, demonstrating the effectiveness of the programme in increasing awareness and adherence to a healthy lifestyle. Education on the dangers of NCDs and the importance of regular health check-ups proved to increase community awareness. Family support and a good understanding of health play an important role in controlling NCDs. This study emphasises the need for prevention programmes and continuous education to reduce the risk of NCDs in the community, as well as the importance of the government's role in providing affordable health services. Thus, collaborative efforts between the community, government and health institutions are needed to improve the quality of life and health of the community in Kajor Kulon. Through this approach, it is hoped that a healthier and more sustainable environment can be created for future generations.
Vitamins Sales Before and During the COVID-19 Pandemic at Network Online Pharmacies in Indonesia Murdiana, Happy Elda; Putri, Mega Karina; Widayati, Aris; Rahmawati, Dewi; Rosita, Melia Eka
JURNAL INFO KESEHATAN Vol 23 No 2 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss2.1518

Abstract

The use of vitamins and micronutrients as an immunity enhancer during the COVID-19 pandemic is needed. The use of vitamins and micronutrients as immunity boosters during the COVID-19 pandemic is very much needed. The description of vitamin needs can be predicted from vitamin sales carried out by network online pharmacies in Indonesia. Vitamins C and E are antioxidants that indirectly have a role as an antiviral. Vitamin D can increase immunity, so its availability is important during the COVID-19 pandemic. This study compares vitamin sales before and during the COVID-19 pandemic at online pharmacies in Indonesia as a description of vitamin use in the community, and their availability by the pharmaceutical industry so that the government can take policies to accelerate this period. The study began by taking master data of all vitamin sales from January 2019 to December 2020 at one of the online pharmacies in Indonesia. Data on all sales each year were grouped based on vitamin content, namely single vitamins, containing two vitamins, and multivitamins (more than two vitamins) and then compared them. Data analysis used the independent t-test, and if the data was not normal and homogeneous, it was processed using the Mann-Whitney test by SPSS version 26 software. The results showed that there was a significant difference between sales of vitamin C (p<0.05), vitamin E (p<0.01), a combination of vitamins B and C (p<0.05), vitamins B and E (p<0.05), and multivitamins (p<0.001) in online pharmacy networks in Indonesia before and during the COVID-19 pandemic. Interestingly, sales of vitamin D did not increase significantly during the COVID-19 pandemic due to limited supplies from pharmaceutical companies even though vitamin D is very important for increasing immunity, thus giving rise to the policy of the Indonesian Ministry of Health to utilize sunlight as the main source of vitamin D.
Enhancing The Understanding of Villagers in Semoyo Patuk Gunungkidul Yogyakarta Regarding Medicinal Chemical in Commercial Natural Products Hadning, Ingenida; Widayati, Aris
ADMA : Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol. 6 No. 1 (2025): ADMA: Jurnal Pengabdian dan Pemberdayaan Mayarakat
Publisher : LPPM Universitas Bumigora

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/adma.v6i1.5102

Abstract

The consumption of herbal medicine in Indonesia has attracted people since ancient times. The trend of consuming jamu is increasing along with the COVID-19 pandemic. Some studies mention that medicinal chemical ingredients are added to marketed natural medicines for a specific purpose, that is not allowed. These medicinal chemicals are known to cause side effects that are very harmful to the body. This reported program aims to improve knowledge regarding the dangers of medicinal chemicals added in marketed natural products. The participants of this program were 30 members of Argomoyo Sejahtera inSemoyo Village, Patuk, Gunung Kidul, Yogyakarta. This program was held on Saturday, May 4th, 2024, at Universitas Muhammadiyah Yogyakarta (UMY). This program was carried out through education about medicinal chemicals added in marketed natural products. Participants were given a questionnaire before and after the education to evaluate their knowledge regarding the delivered materials. Data of the pre and post test were analysed using paired sample t-test.  The results show that there is a significant increase in participants' knowledge, with a p-value of 0.017 (<0.05). These results indicate that education could effectively enhance knowledge about medicinal chemicals' dangers which are added to marketed natural products.
EVALUASI PENGGUNAAN ANTIBIOTIKA DENGAN METODE DDD (DEFINED DAILY DOSE) PADA PASIEN ANAK RAWAT INAP DI SEBUAH RUMAH SAKIT PEMERINTAH DI YOGYAKARTA PERIODE JANUARI - JUNI 2013 Carolina, Maria; Widayati, Aris
Media Farmasi: Jurnal Ilmu Farmasi Vol. 11 No. 1: Maret 2014
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v11i1.1400

Abstract

Antibotika banyak diresepkan pada pasien anak. Penggunaan antibiotika yang berlebihan berkontribusi pada resistensi. Penelitian ini bertujuan mengevaluasi penggunaan antibiotika pada pasien anak rawat inap di sebuah rumah sakit pemerintah di Yogyakarta menggunakan metode DDD (Defined Daily Dose).Jenis dan rancangan penelitian adalah deskriptif cross-sectional,dengan data retrospektif. Data penggunaan antibiotika diperoleh dari 249 rekam medik periode rawat Januari – Juni 2013 yang dipilih dengan metode simple random sampling. Data yang diambil meliputi profil pasien, diagnosis, dan peresepan antibiotika. Kuantitas penggunaan antibiotika dihitung dengan rumus DDD 100 patient-days. Data dianalisis secara deskriptif.Hasil penelitian menemukan 28 jenis antibiotika yang diresepkan, dengan total nilai DDD 100 patient-days sebesar 41,99. Nilai DDD tertinggi yaitu ampisilin (10,33) dan merupakan antibiotika yang paling sering diresepkan (13,9%).Dapat dikatakan bahwa pemilihan antibiotika di rumah sakit tersebut masih belum selektif.
Inhibition of Neurogenesis and Induction of Glial Scar Formation by Neuroinflammation Following Ischemic Stroke: Evaluation of BDNF, GFAP, HMGB1 and TNF-α Expressions Widayati, Aris; Rantam, Fedik Abdul; Machin, Abdulloh; Riawan, Wibi
The Indonesian Biomedical Journal Vol 17, No 1 (2025)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v17i1.3439

Abstract

BACKGROUND: Ischemic stroke remains as a major health problem and one important process in Ischemic Stroke is neuroinflammation which has a principal role to maintain the balance of neurogenesis and neurodegeneration process in the brain. Neuroinflammation can lead to glial scar and inhibit neurogenesis processes which is needed for recovery neuron function. This study was conducted to observe the role of high mobility group box 1 (HMGB1) and tumor necrosis factor-α (TNF-α) as neuroinflammation markers to glial fibrillary acidic protein (GFAP) as glial scar marker and to brain-derived neurotrophic factor (BDNF) as neurogenesis marker in brain tissue following ischemic stroke.METHODS: Fifteen male Wistar rats were randomized to three groups; sham group, rats receiving occlusion and terminated 180 minutes later (group A), and rats receiving occlusion and terminated after 7 days (group B). Expressions of BDNF and BDNF mRNA were examined using immunohistochemistry (IHC) and Reverse Transcription Polymerase Chain Reaction (RT-PCR), respectively. While GFAP, HMGB1, TNF-α were assessed using IHC.RESULTS: Expression of BDNF was found lower in group A and group B than in sham group (5.20±1.924, 5.00±1.581, and 7.80±1.304, respectively; p=0.032). Expression of BNDF mRNA was found lower in group A and B than in sham group as well. While expression of GFAP was found higher in group A and B than in sham group (9.60±1.517, 11.40±2.074, and 5.20±1.48, respectively; p=0.000). Higher level of HMGB1 and TNF-α expressions were also found to in group A and group B than in sham group (9.3±1.528, 11.67±1.528, and 2.00±1.000, respectively; p=0.000 for HMGB1 and 6.33±1.155, 9.33±1.528, and 3.00±1.000, respectively; p=0.002 for TNF-α).CONCLUSION: The presence of low BDNF levels and high levels of GFAP, HMGB1 and TNF-α markers, possibly reflects inhibition of the neurogenesis process by neuroinflammation, and induced glial scar formation in ischemic stroke conditions after than 180 hours until 7 days. KEYWORDS: ischemic stroke, BDNF, GFAP, TNF-α, HMGB1
Penerapan Sistem Informasi Pengelolaan Obat di Instalasi Farmasi Rumah Sakit Umum Daerah (RSUD) Menggunakan Pendekatan HOT-FITPenerapan Sistem Informasi Pengelolaan Obat di Instalasi Farmasi Rumah Sakit Umum Daerah (RSUD) Menggunakan Pendekatan HOT-FIT: IMPLEMENTATION OF DRUG MANAGEMENT INFORMATION SYSTEM IN PHARMACY INSTALLATION OF REGIONAL GENERAL HOSPITAL USING HOT-FIT APPROACH Azizatunnisa, Rahmatia; Ghozali, Muhammad Thesa; Ahyar, Zeda Kumala; Dewi, Pramitha Esha Nirmala; Widayati, Aris
JFL : Jurnal Farmasi Lampung Vol. 14 No. 2 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/rvts9708

Abstract

Implementasi lapangan Sistem Informasi Manajemen Pengelolaan Obat (SIM-PO) di instalasi farmasi rumah sakit menuntut keselarasan faktor manusia, organisasi, serta teknologi agar berdampak pada mutu layanan dan efisiensi logistik. Tujuan penelitian ini adalah untuk menganalisis pengaruh dari Human, Organization, dan Technology terhadap keberhasilan penerapan SIM-PO di Instalasi Farmasi Rumah Sakit Umum Daerah (RSUD) yang berlokasi di sebuah kabupaten di Daerah Istimewa Yogyakarta, Indonesia menggunakan metode HOT-FIT. Metode penelitian yang digunakan adalah studi kuantitatif cross-sectional pada 35 tenaga kefarmasian dari berbagai unit kerja, menggunakan kuesioner yang valid dan reliabel; analisis ini dilakukan dengan Partial Least Squares (SmartPLS 3.0). Hasil penelitian membuktikan bahwa ketiga dimensi berpengaruh signifikan terhadap implementasi SIM-PO di instalasi farmasi; domain Human (β=0,364; t=3,231; p=0,0013), Organization (β=0,334; t=2,812; p=0,0051), dan Technology sebagai determinan paling dominan (β=0,442; t=3,676; p=0,0003). Penelitian ini menyimpulkan bahwa keberhasilan implementasi sistem ini ditentukan oleh kualitas teknis dan layanan TI, dukungan organisasi (kebijakan, kepemimpinan, pelatihan), serta kompetensi dan kepuasan pengguna. Selain itu, implikasi praktiknya adalah prioritas peningkatan keandalan sistem informasi obat dan interoperabilitas, program peningkatan kapasitas pengguna berbasis kebutuhan unit, serta tata kelola dan dukungan manajerial yang konsisten.
Co-Authors Abadi, Barnabas Bagus Aditya Affan, Muhammad Ahyar, Zeda Kumala Alfiani, Dhea Fita Ayu, Yuniarti Mega Azizatunnisa, Rahmatia Cahyani, Riska De Karos, Vlorent Anggi DEWI RAHMAWATI Dita Maria Virginia Dwi Yuni Nur Hidayati Erna Tri Wulandari Fahrezy, Ergi Ahmad Fedik Abdul Rantam Fenty Fenty, Fenty Happy Elda Murdiana, Happy Elda Harahap, Feby Nur Alyani Hartayu, Titien S. Ingenida Hadning Laksmi Wulandari Machin, Abdulloh Maria Carolina Mohammad Saiful Islam, Mohammad Saiful Muhammad Thesa Ghozali Muna, Wildan Syithrul Permana, Mohammad Rafli Phebe Hendra, Phebe Pradhana, Muhamad Ilham Satya Pramitha Esha Nirmala Dewi, Pramitha Esha Nirmala Pratiwi, Fransiska Indah Prayata, Kenzie Wistara Putri, Andhini Eka Putri, Mega Karina Putri, Zahra Saphira Rahajeng, Bangunawati Rahayu, Safira Sri Rifa’i, Putri Fadia Rifqiyah, Iffatur Rima Nor Kaspia, Rima Nor Rosita, Melia Eka Sisca Dewi Karlina, Sisca Dewi Subandi Subandi Sukoco, Naura Hasyifa Anindya Syuja, Najmie Muhammad Wibi Riawan Wulandari, Endaryanti Yebi, Saffana Racho Mauluda Yosef Wijoyo, Yosef Zakwan, Hazy Rizali Ziv, Khansa Fikriyah ‘Azhim, Muhammad Fauzan