Article Per Year (5 Year)
p-Index From 2021 - 2026
4.548
P-Index
This Author published in this journals
All Journal Buletin Udayana Mengabdi E-Jurnal Medika Udayana Jurnal Vektor Penyakit Dinamisia: Jurnal Pengabdian Kepada Masyarakat WICAKSANA: Jurnal Lingkungan dan Pembangunan Muhammadiyah Medical Journal Aesculapius Medical Journal Warmadewa Minesterium Medical Journal Medika Respati : Jurnal Ilmiah Kesehatan Community Services Journal (CSJ)
Ni Wayan Widhidewi
Universitas Warmadewa
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Education Environmental Science Health Professions Immunology & microbiology Library & Information Science Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 24 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 6 Documents
Search
Journal : Aesculapius Medical Journal

 1 
Hubungan Leukopenia dengan Tingkat Keparahan Demam Berdarah Dengue pada Anak di RSUD Wangaya Denpasar pada Januari-Agustus 2021 Anak Agung Ngurah Arya Yugadhyaksa; Ni Kadek Elmy Saniathi; Ni Wayan Widhidewi
Aesculapius Medical Journal Vol 4 No 1 (2024): February
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.4.1.2024.129-135

Abstract

[The Correlation Between Leukopenia and The Severity of Dengue Hemorrhagic Fever in Paediatric Patients of RSUD Wangaya Denpasar from January 2021-August 2021] Dengue Hemorrhagic Fever (DHF) is one of the most concerning diseases to look out for each year especially on paediatric patients because pediatric patients are more susceptible to severe dengue infection. This is presumably because the microvasculature in children is more prone to plasma leakage. To measure the severity of DHF, a classification by World Health Organization (WHO) in 2011 is used mainly as the standards. This study aims to determine the relationship between leukopenia and the severity of dengue fever in children treated at Wangaya Regional Hospital, Denpasar. The methods this study used is an observational analytic method with cross sectional study by using medical reports as secondary data from January-August 2021 in RSUD Wangaya Denpasar. Subjects are obtained by consecutive sampling with 92 subjects. This study used chi-square analysis (x2) with 95% confidence interval (CI) and P-value of 5%. Data was analyzed using univariate and bivariate model through Statistical Package for the Social Sciences for Windows. The results of this study indicates that the number of subjects with non-shock hemorrhagic dengue fever which is 68.5% appears to be greater than subjects with shock dengue hemorrhagic fever which is 31.5%. The average leukocyte level in the subjects obtained was still in the normal range, namely 4,803 µL. Chi square (x2) distribution table analysis (p=0,092), there is no significant correlation between the leukopenia with the severity of dengue hemorrhagic fever in paediatric patients of RSUD Wangaya Denpasar.
Gambaran Faktor Risiko Kejadian Pterygium pada Pasien di Poliklinik Mata Rumah Sakit Umum Daerah Tabanan I Putu Baskara Adi Dananjaya; Ni Wayan Widhidewi; Ni Nyoman Sunariasih
Aesculapius Medical Journal Vol 4 No 1 (2024): February
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.4.1.2024.41-46

Abstract

Pterygium is a degenerative and invasive fibrovascular growth of the conjunctiva that extends to the cornea in a triangular shape with an apex in the corneal area. The incidence of pterygium in Indonesia is still relatively high as much as 13,1% with the highest prevalence found in Bali at 25,2%. The aim of this study was to determine the risk factors for the occurrence of pterygium including age, gender, and place of residence that could affect the occurrence of pterygium at the Eye Polyclinic of Tabanan Hospital and was conducted from January 2022 – August 2022. The study used descriptive design with a cross-sectional approach. The number of subjects was 102 patients that have met the inclusion and exclusion criteria. This study used a secondary data from medical records of pterygium patients in Eye Polyclinic of Tabanan Hospital. The result showed that the incidence of pterygium in the Eye Polyclinoc of Tabanan Hospital was obtained among as many as 84,3% of the subjects. The early elderly group in the range of 46 – 55 years were 36 (35,3%) subjects, 77 (75,5%) of the subjects were women, and 65 (63,7%) of subjects lived in rural areas. It is hoped that this research can be used as aadditional information, and for the agency that is the location of the research, which is the Eye Polyclinic of Tabanan Hospital to improve the recording of medical records so that the information obtained is mor accurate.
Skrining Aktivitas Antibakteri Bacillus sp. PCAR1 dari Rumput Laut Eucheuma spinosum terhadap Bakteri Staphylococcus aureus Ni Made Alit Yulianti; Anak Agung Gede Indraningrat; Ni Wayan Widhidewi
Aesculapius Medical Journal Vol 4 No 2 (2024): June
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.4.2.2024.165-171

Abstract

[Antibacterial Activity Screening of Bacillus sp. PCAR1 from Seaweed Eucheuma spinosum against Staphylococcus aureus bacteria] Microorganisms associated with marine organisms have the potential to produce secondary metabolite compounds with strong antibacterial activity. Previous research has isolated Bacillus sp. bacteria encoded as PCAR1 from Eucheuma spinosum seaweed with antibacterial potential against Gram-positive and Gram-negative bacteria. However, the potential bioactivity produced by bacillus sp. PCAR1, especially as an antibacterial against Staphylococcus aureus, still needs to be explored using chemical extraction method. In this research, a total of 100 mL of sterile NB liquid media containing the cell mass of Bacillus sp. PCAR1 was fermented for 5 days and then shaken at 150 rpm. The supernatant was separated from the cell mass by filtration using Whatman filter paper no.1.The filtrate was extracted using ethyl acetate pro-analytics (1:1 v/v). The extracts were analyzed for antibacterial activity using the Kirby-Bauer method, while the chemical composition of the extracts was analyzed using gas chromatography-mass spectrometry (GC/MS) method. Antibacterial screening of ethyl acetate extract of Bacillus sp. PCAR1 showed an inhibition zone of 6.23±0.06 mm against Staphylococcus aureus ATCC 25293, which is classified as moderate antibacterial activity. GC/MS analysis showed that the ethyl acetate extract contained 10 chemical compounds that have potential as antibacterial, with four dominant active compounds namely p-Xylene (7.26%), Ethanol, 2-butoxy (5.36%), o-Xylene (3.14%), and mesitylene (3.41%). Overall, these results provide an initial overview of antibacterial compounds that can be synthesized by Bacillus sp. PCAR1.
Skrining Aktivitas Antibakteri dan Antijamur dari Isolat Bakteri Marinobacter Hydrocarbonoclasticus NAR7 I Gusti Gde Agung Anantawikrama; Anak Agung Gede Indraningrat; Ni Wayan Widhidewi
Aesculapius Medical Journal Vol 4 No 3 (2024): October
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.4.3.2024.293-302

Abstract

Infectious diseases caused by bacteria and fungi are global health issues, including in Indonesia. Previous studies reported one bacterial isolate associated with the seaweed Caulerpa lentillifera, namely Marinobacter hydrocarbonoclasticus NAR7, which showed antibacterial activity against Streptococcus mutans based on the perpendicular streak method. This study is alaboratory research with a descriptive method. Isolate M. hydrocarbonoclasticus NAR7 was grown in 100 mL of nutrient broth supplemented with artificial seawater for seven days. The obtained supernatant was separated from the cell mass by filtration, and the supernatant was extracted with ethyl acetate at a ratio of 1:1 (v/v) and further evaporated at 40°C to obtain a thick extract. The crude ethyl acetate extract obtained was tested against Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Streptococcus mutans FNCC 0405), and Gram-negative bacteria (Escherichia coli ATCC 25922, and Klebsiella pneumoniae ATCC 700603) using the Kirby-Bauer method. Screening results showed that the extract was only active against Staphylococcus aureus ATCC 25923 with an average inhibitory zone diameter of 7.32±0.57 mm, which is classified as moderate antibacterial activity. Meanwhile, the extract did not form inhibitory zone diameters against other test bacteria. Antifungal screening showed that the extract could not inhibit the growth of Candida albicans and Aspergillus flavus fungi. These results overall indicate the initial potential of antibacterial activity from the M. hydrocarbonoclasticus NAR7 isolate. Further optimization efforts, including extraction with different solvents, are required.
Skrining Fitokimia, Aktivitas Antibakteri, dan Antijamur Ekstrak Etil Asetat Biji Lamtoro (Leucaena leucocephala) Dewa Ayu Mas Maharani; Anak Agung Gede Indraningrat; Ni Wayan Widhidewi
Aesculapius Medical Journal Vol 5 No 1 (2025): February
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.5.1.2025.47-57

Abstract

The entry of bacteria and fungi into the body is one of the causes of infectious diseases. However, the use of synthetic antibiotics and antifungals often causes resistance effects by pathogenic microorganisms. One effort to overcome bacterial and fungal resistance is to explore secondary metabolite compounds from herbal plants and one of them is the seeds of the lamtoro plant (Leucaena leucocephala). Previous research has reported the antibacterial potential of lamtoro seeds. However, the information reported is not comprehensive because it was only tested using ethanol solvent. Apart from that, research on the antifungal activity of lamtoro seeds has never been reported. This research design uses laboratory experimental methods. The initial stage is plant identification and continued with extraction of lamtoro seed simplicia using ethyl acetate solvent with a ratio (1:5 w/v) for 24 hours and simplicia remaceration is carried out again for 24 hours. The resulting extract will be tested for its phytochemical content. Next, the extract will be tested for antibacterial and antifungal activity using the Kirby-Bauer method. The test bacteria used were Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Streptococus mutans FNCC 0405, and Klebsiella pneumoniae ATCC 700603. The test fungi used were Candida albicans and Aspergillus flavus. The results of phytochemical screening showed that the ethyl acetate extract of lamtoro seeds contained flavonoids, saponins and tannins. Meanwhile, the antibacterial activity test of the ethyl acetate extract of lamtoro seeds showed that there was no antibacterial inhibitory effect on Gram-negative or Gram-positive bacteria. The antifungal screening showed that the extract did not display antifungal activity against tested fungal indicators.  
Hubungan Usia dan Jenis Kelamin dengan Kejadian Otitis Media Supuratif Kronik di RSUD Wangaya Tahun 2018 - 2024 Pande Made Adhitya Yogantara; Ni Wayan Widhidewi; Agus Santosa
Aesculapius Medical Journal Vol 5 No 2 (2025): June
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.5.2.2025.113-121

Abstract

Otitis Media Supuratif Kronik (OMSK) merupakan infeksi kronis pada telinga tengah yang ditandai dengan adanya perforasi atau kerusakan pada membran timpani, yang berlangsung selama lebih dari dua bulan, baik secara terus-menerus maupun kambuhan. Terdapat dua jenis OMSK yaitu tipe tubotimpani atau yang tidak berbahaya dan tipe atikoantral atau jenis yang cukup berbahaya. Kejadian tersering terjadi pada anak-anak hingga dewasa muda dan jenis kelamin laki-laki lebih banyak terdampak karena dikaitkan dengan aktifitas fisik yang lebih banyak dan pola hidup kurang sehat dibandingkan perempuan.
Co-Authors A.A.A.L. Paramasatiari A.A.G. Indraningrat Agus Santosa Alit Yulianti, Ni Made Anak Agung Ayu Lila Paramasatiari Anak Agung Gede Indraningrat Anak Agung Ngurah Arya Yugadhyaksa Anak Agung Ngurah Arya Yugadhyaksa Anak Agung Sagung Ayu Santhi Sueningrum budiapsari, putu indah D.A.P.S. Masyeni Dewa Ayu Mas Maharani Dewa Putu Widjana Dharmesti Wijaya Dharmesti Wijaya Erly Sintya Hegard Sukmawati, Ni Made I Gusti Gde Agung Anantawikrama I Putu Baskara Adi Dananjaya K Tangking Widarsa Kapti I Nengah L. Suriati Luh Suriati Muliawan, Ketut Hari Ni Kadek Elmy Saniathi Ni Luh Putu Eka Kartika Sari Ni Made Alit Yulianti Ni Nyoman Sunariasih Ni Putu Diah Witari, Ni Putu Ni Wayan Winianti P. A. Suryanditha P. I.B. Apsari P. Sutisna P.I.B. Apsari Pande Ayu Naya Kasih Permatananda Pande Made Adhitya Yogantara Putu Arya Suryanditha Putu Indah Budi Apsari Putu Indah Budi Apsari Putu Sutisna Wirawan, Ady