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All Journal Jurnal AGROTEKNOLOGI Jurnal Kedokteran Brawijaya Journal of Innovation and Applied Technology Research Journal of Life Science Jurnal Pangan dan Agroindustri Jurnal Teknologi Pertanian Indonesian Journal of Human Nutrition agriTECH Biology, Medicine, & Natural Product Chemistry Industria: Jurnal Teknologi dan Manajemen Agroindustri Amerta Nutrition Food Science and Technology Journal (Foodscitech) Advances in Food Science, Sustainable Agriculture and Agroindustrial Engineering (AFSSAAE) Nusantara Science and Technology Proceedings Jurnal Teknologi Pangan
Tri Dewanti Widyaningsih
Universitas Brawijaya
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Other

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Journal : Research Journal of Life Science

 1 
Extraction of Glycosaminoglycans Containing Glucosamine and Chondroitin Sulfate from Chicken Claw Cartilage Tri Dewanti Widyaningsih; Widya Dwi Rukmi; Erni Sofia; Sudarma Dita Wijayanti; Novita Wijayanti; Rika Ersalia; Nia Rochmawati; Debora Nangin
Research Journal of Life Science Vol 3, No 3 (2016)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (561.475 KB) | DOI: 10.21776/ub.rjls.2016.003.03.7

Abstract

Chicken cartilage (claw) is a waste of chicken cuts which are widely available in Indonesia. Cartilage part of chicken claw becomes a potential source of chondroitin sulfate (CS) and glucosamine (GS). This study aims to determine the most optimal extraction methods of CS and GS from cartilage of chicken claw. Various types of extraction methods used in this study are taken from the extraction by using boiling water (2 and 2.5 hours), acetic acid (7 and 17 hours), as well as proteolysis by papain (24 and 48 hours). Parameters observed include chemical characteristics of powdered cartilage of chicken claw as well as CS and GS levels in powdered cartilage of chicken claw extract. The results of this research show that the levels of CS and GS of chicken claw cartilage powder were 2.17% and 13%. Meanwhile, the highest GS level was obtained from the extraction with water treatment for 2.5 hours which was 8.1%. The treatment and duration of extraction will significantly affect the number of GS which was produced. The highest content of CS was obtained from the extraction with the enzyme treatment for 48 hours which was 2.47%. The best treatment is the extraction with water treatment for 2.5 hours which were the extracts with GS levels of 8.1% and 2.03% CS was selected through the analysis of multiple attribute. 
Antihypertensive Effects of Black Cincau (Mesona palustris BL) Effervescent Powder and Malondialdehyde Concentration on Wistar Rats as a Hypertensive Model Tri Dewanti Widyaningsih; Novita Wijayanti; Dian Handayani; Guntur Prasetyo
Research Journal of Life Science Vol 3, No 2 (2016)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (712.972 KB) | DOI: 10.21776/ub.rjls.2016.003.02.2

Abstract

This study investigated the effects of Black cincau (Mesona palustris BL) effervescent powder (BCEP) on systolic blood pressure and malondialdehyde concentration in hypertensive rats. BCEP were orally administered to hypertensive rats for 4 weeks, and antihypertensive effects were determined. Rats were given 630 mg/kg, 1.260 mg/kg and 1.890 mg/kg BCEP on dose group 1, 2, 3 respectively. These groups were  compared with a negative control group, hypertensive control group and Captopril control group. These results showed that systolic blood pressure and MDA concentrations of rats dosed with BCEP were significantly different (α=0,01) to those of control rats. Rats dose third group with of 1.260 mg/kg showed the highest percentage of lowering blood pressure. The rat dose third group had highest percentage decreased in systolic blood pressure (43,97%) and in MDA concentration (68,77%).Key words : Antihypertensive; Black Cincau (Mesona palustris BL) Effervescent Powder; Malondialdehyde 
Black Grass Jelly (Mesona Palustris Bl) Effervescent Powder has Anti-Dyslipidemia in High Cholesterol Diet-Fed Rats and Antioxidant Activity Dian Handayani; Tri Dewanti Widyaningsih; Novita Wijayanti; Mey Etika
Research Journal of Life Science Vol 4, No 3 (2017)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (618.057 KB) | DOI: 10.21776/ub.rjls.2017.004.03.1

Abstract

Dyslipidemia that could be affected by hypercholesterol diet is a contributing factor in millions of deaths worldwide and a risk factor for ischemic heart disease and stroke. High soluble fiber diet is used as one of the non-pharmacological treatments to control hypercholesterolemia. Black Grass Jelly (Mesona palustris BL) also known as black cincau has a high soluble fiber content. This study aimed to investigate the effect of black cincau as effervescent powder form (BCEP) for anti-dyslipidemia and also the antioxidant activity. BCEP was orally administered to twenty male dyslipidemia Wistar rats induced with hypercholesterol diet for 3 weeks then plasma lipid profile was measured using enzymatic CHOD-PAP assay. The antioxidant activity also has been identified. Oral administration of 3 different doses of BCEP resulted in lipid profiles by decreasing plasma cholesterol (TC), triacylglycerol (TG), low-density lipoprotein (LDL), and also high-density lipoprotein (HDL) in dyslipidemia rats (α =  0.01). The increasing doses of BCEP revealed that it has a potential effect of decreasing plasma lipid.
Co-Authors Addiena Hidayati Addiena Hidayati, Addiena Adin Pritanggo Dhesti Adin Pritanggo Dhesti Agustina Maria Dwiyanti Soeyono Agustina Tri Endharti Annisa Ulfah Pristya Arya Ulilalbab Atika Ruri Cahyaningrum Atika Ruri Cahyaningrum, Atika Ruri Aulia Shabrina Karismawati Aulia Shabrina Karismawati Aulia Shabrina Karismawati Ayu Arditiana Ayu Arditiana Bobby Andi Septian Bobby Andi Septian Christiani Tangkeallo Christiani Tangkeallo Christine Eka Wulandari Harianto Chyntia Trivena Milala Debora Nangin Dego Yusa Ali Dian Ekasari Dian Handayani Dian Handayani Dian Kasseri Dian Widya Ningtyas Dzulvina Utami Dzulvina Utami Dzurratun Nafisah Ega Parastra Maurinho Ega Parastra Maurinho, Ega Parastra Eka Novanti Eka Novanti, Eka Elok Waziiroh Endah Trinafianita Endrika Widyastuti Eriyanto Yusnawan Erni Sofia Erryana Martati Feronika Heppy Sriherfyna Feronika Heppy Sriherfyna Firda Yusrina Guntur Prasetyo Guntur Prasetyo Guntur Prasetyo Hanny Nurhalimah Hanny Nurhalimah Henita Listianing Raji Putri Henita Listianing Raji Putri, Henita Listianing Raji Hera Sisca Prasmita, Hera Sisca Heri Wahyono Heri Wahyono I Ketut Suada Ika Nur Fauzziyah Ika Nur Fauzziyah, Ika Nur Indira Nur C. Itsna Zaky Zumroh Jaya Mahar Maligan Jaya Mahar Maligan Jaya Mahar Maligan Jaya Mahar Maligan Jaya Mahar Maligan Jaya Mahar Maligan Jayanti, Theresia Vania Jhauharotul Muchlisyiyah Jhauharotul Muchlisyiyah, Jhauharotul Kemala Febrianti Kemala Febrianti KIKI FIBRIANTO Lailatul Fitriani Lailina Mufida Lailina Mufida Leenawaty Limantara M Wahid Wahyu Kurniawan Maramy, Neyla Vista Marcelia, Ela Mega Ayu Bunga Dewi Mega Leny Puspitasari Mega Leny Puspitasari Mey Etika Mey Etikasari Miptakhul Hudha Miptakhul Hudha Mochamad Afif Sholichudin Mochamad Afif Sholichudin, Mochamad Afif Muhammad Fawzul Alif Nugroho Muhammad Fawzul Alif Nugroho Musthikaningtyas Retno Palupi Musthikaningtyas Retno Palupi Nabilah Mei Wulandari Nabilah, Anjar Asmarani Widya Naomi Megananda Mulyadi Naomi Megananda Mulyadi, Naomi Megananda Nela Purwani Septiyanti Nela Purwani Septiyanti, Nela Purwani Nia Rochmawati Nia Rochmawati Nia Rochmawati Nike Nurlaily Fitria Nirmala Nurhasanah Nirmala Nurhasanah Nirmala Nurhasanah Novita Wijayanti Novita Wijayanti Novita Wijayanti Novita Wijayanti Nur Ida Panca Nugrahini Nurul Abidah Nurul Abidah Nurul Fahmi Rizkia Nurul Fahmi Rizkia, Nurul Fahmi Okkie Dhyantari Okkie Dhyantari Pandu Salim Hanafi Pawestriaji, Raihanurrabb Prajwalita Rukmakharisma Rizki Prajwalita Rukmakharisma Rizki Pramita, Hera Sisca PRASETYAWAN YUNIANTO Pratiwi, Devitasari Dian Puruhito Widinugroho Putri Puncak Anjani Putri Puncak Anjani Rachmad Rizal Yulianto Rachmad Rizal Yulianto Rahma Maya Safitri Rani Puspitasari Renny Dwi Puspitasari Renny Indrawati Renny Indrawati, Renny Retno Wulansari Rika Ersalia Rizca Dwi Jayanti Rizki Amelia Rizki Amelia Robbit Farid Wajdi Rofiqoh Fajarwati Saadatul K.S Sabrina W Purbasari, Sabrina W Sapitri, Nia Shelly Andrianty Siti Narsito Wulan Sofie Imsa Fitriyaningtyas Sofie Imsa Fitriyaningtyas Sudarma Dita Wijayanti Sudarma Dita Wijayanti Sudarma Dita Wijayanti Syafrilia, Rosita Mega Syafrilia, Rosita Mega Tabita Hasian Tara Viantya Wulansari Wafa, Nurul Widya D.R. Putri Widya Dwi Rukmi Wijayanti, Novita Paskarinda Wijayanti, Novita Wijayanti Wijayanti, Novita Wijayanti Winda Rein Nimas Tasia Winda Rein Nimas Tasia Wulandari, Diana Candra Yulina Lailatul Maslukhah Yulina Lailatul Maslukhah Yunia Galih Purwaningdyah Yunia Galih Purwaningdyah