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All Journal Jurnal Kesehatan Andalas Riau Journal of Computer Science Sari Pediatri MUDRA Jurnal Seni Budaya Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Buletin Ilmiah Nagari Membangun Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Kesehatan Komunitas Indonesia RJOCS (Riau Journal of Computer Science)
Efrida
Departemen Patologi Klinik Dan Kedokteran Laboratorium, Fakultas Kedokteran, Universitas Andalas
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Glycemic control and serum albumin in type 2 diabetes patients: What does observational study say? Yosa, Nelvia Okta; Efrida
Majalah Kedokteran Andalas Vol. 46 No. 3 (2023): Supplementary July 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i11.p1790-1800.2024

Abstract

Glycemic control is important to prevent organ damage in Type 2 Diabetes Melitus (T2DM) Patients, especially liver and kidney. One of parameter used to see the decreasing function of both organs is serum albumin. Aim : The aim of this study was to identify the association between glycemic control and serum albumin level on T2DM patoents. Method :  This is an observational analytical study using cross sectional design. This study was conducted at RSUP Dr. M. Djamil Padang using T2DM patients medical records on 2019-2021. The level of HA1c <7% was cathegorised as good glycemic control and Hb1c >7% was cathegorised as poor glycemic control. Results : The results showed that there was an association between glycemic control and serum albumin level on T2DM patients at RSUP Dr. M. Djamil Padang. Conclusion : Glycemic control was inversely associated with serum albumin levels in patients with T2DM in RSUP Dr. M. Djamil Padang
The Effect of Anesthesia on TGF-β Levels in Lung Tumor Patients Undergoing Bronchoscopy: A Literature Review Johannas; Efrida; Basyar, Masrul; Darwin, Eryati
Jurnal Kesehatan Komunitas Indonesia Vol 6 No 1: April 2026
Publisher : Al-Hijrah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58545/jkki.v6i1.713

Abstract

Lung cancer remains the leading cause of cancer-related mortality worldwide, with persistently low survival rates. Bronchoscopy is an essential diagnostic procedure in patients with lung tumors and often requires anesthesia to improve comfort and procedural success. Emerging evidence suggests that anesthetic agents and techniques may influence tumor biology through modulation of immune responses and inflammatory mediators. Transforming Growth Factor-Beta (TGF-β) is a multifunctional cytokine involved in cell proliferation, differentiation, immune regulation, and extracellular matrix remodeling, and plays a critical role in cancer progression. This literature review aims to evaluate current evidence regarding the effects of anesthetic agents and techniques on TGF-β levels and their implications for tumor biology in patients with lung tumors undergoing bronchoscopy. A narrative literature review approach was used to analyze scientific publications exploring the relationship between anesthesia, immune modulation, cytokine alterations, and cancer progression, particularly focusing on inhalational and intravenous anesthetics. Surgical stress and anesthetic exposure can alter immune responses through activation of neuroendocrine pathways, leading to cytokine imbalance and immunosuppression. TGF-β exhibits dual roles in cancer, acting as a tumor suppressor in early stages and a tumor promoter in advanced stages. Inhalational anesthetics may enhance tumor progression, whereas intravenous anesthetics such as propofol may have immunomodulatory effects. Anesthetic techniques may influence tumor-related pathways, including TGF-β; however, evidence remains limited and inconsistent, requiring further well-designed studies.
Co-Authors Ade Asyari Al Hafiz Almurdi Almurdi Amanda, Dela Sasqia Basorudin Bestari Jaka Budiman Budi Setyastuti Desywar Desywar Dia Rofinda, Zelly Dia Doan Atrya Dolly Irfandy Dwitya Elvira, Dwitya Effy Huriyati Elfira Yusri Erni Rouza Erni Rouza, Erni Eryati Darwin Fachzi Fitri Fadhilaturrizqie Siregar Fika Tri Anggraini Finny Fitry Yani Firdawati Franesia - Dwirahmana Gestina Aliska Ghina Zartin Herman, Deddy Hidayat, Hedo Husni Ida Rahmah Burhan Ihsan, Rafiq Ikhsan Marzony Indah Fitriani Indah Sulastuti, Katarina Indra Ihsan Jacky Munilson Johannas Kenny Mamik Widyastuti Masrul Basyar Nanda Oktavia Nirza Warto Novialdi . Nuryanto Putri, Andina Ayu Rahmadina, Rahmadina Raisa Putri Secioria Raveinal Reni Asprilia Reza , Mohamad Rismawati Yaswir Rismawati Yaswir Rossy Rosalinda Russilawati, Russilawati Setya Widyawati Silvia Rega Sri Vanny Suhirman Sukri Rahman Sunardi Syofiati Syofiati Syofiati Syofiati Syofiati Ulti, Zifa Amanda Wahid , Irza Yan Edward Yessi Yestiani Yosa, Nelvia Okta