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Optimization Of Isolation Method Of Carrageenan From Kappaphycuss Alvarezii Doty Using Factorial Experimental Design Ketut Widyani Astuti; Ni Putu Ayu Dewi Wijayanti; I Gusti Ngurah Agung Dewantara Putra; Ni Putu Linda Laksmiani
Journal of Health Sciences and Medicine Vol 1 No 2 (2017): JHSM (September 2017)
Publisher : Institute for Research and Community Services Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (232.941 KB)

Abstract

Kappaphycus alvarezii Doty is a species of red algae ( Rhodophyceae) producing kappa carrageenan. The value of carrageenan will increase if it is able to form thermoreversible gels. The quality of carrageenan is determined by the isolation method which includes several stages, namely soaking, extraction, purification, and drying. This study aims to obtain an optimum isolation method of carrageenan from seaweed Kappaphycus alvarezii Doty using the factorial experimental design software, Design Expert Version.7.0.0. with the characteristics that meet the standards set by FAO. The seaweed was collected from the sea in Nusa Lembongan, Bali Province. The carrageenan isolation method was optimized by varying three factors, namely the concentration of NaOH (4% and 8%), extraction time (0.5 hour and 3 hours), and precipitation time (0.25 hour and 0.5 hour) in order to obtain 8 formulae which then went through an evaluation of the physical and chemical characteristics of the carrageenan. The physical and chemical characteristics include the yield, viscosity, sulfate content, and ash content, analyzed using Design Expert Version 7.0.0 program to determine the optimum method of isolation. The analysis showed that the optimum method of carrageenan isolation was using NaOH with a concentration of 4.40%, the extraction time of 2.16 hours and the precipitation time of 0.29 hour. The physical and chemical characteristics of carrageenan with the optimum isolation method include the yield of 25.73%, the viscosity of 11.92 cPs, sulfate content of 31.95% and the ash content of 26.16% which have met the standards set by FAO.
Pengembangan Kuisioner Udayana untuk Penilaian Kepuasan Pasien terhadap Pelayanan Kefarmasian oleh Apoteker di Pusat Kesehatan Masyarakat Luh Putu Febryana Larasanty; Made Krisna Adi Jaya; Ketut Widyani Astuti; I Wayan Martadi Santika
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.60998

Abstract

The implementation of pharmaceutical care by pharmacists at the community health center has been regulated in the Minister of Health Regulation No. 74 of 2016. Based on that regulation, assessment of pharmaceutical care services is needed to ensure the quality of services provided by pharmacists. This study aims to develop an Udayana questionnaire that can be used to evaluate the quality of pharmaceutical care provided by pharmacists at community health centers. This research is quantitative (survey implementation) carried out in 2 phases. The first phase is the design of the Udayana questionnaire. The second phase is to verify the validity and reliability of the questionnaire. The questionnaire validity test was carried out in three stages, namely the logical validity test, content validity, and construct validity. The questionnaire statement develop based on Minister of Health Regulation No. 74 of 2016 obtained 31 statements which are divided into 5 dimensions of service quality. The logical validity test resulted in 30 statements that were declared valid by experts. Content validity test is done by calculating the value of the content validity ratio (CVR) and the value of the content validity index (CVI). The CVR and CVI results showed that 7 statements were eliminated because they were not valid (CVR value <0.99 and CVI <70%). Construct validity test and questionnaire reliability were tested on 384 respondents who had met the inclusion criteria. The construct validity test resulted 23 valid statement (r = 0.148). Results of the reliability test based on Cronbach's Alpha value is greater than 0.6, indicating that all the valid statement items in the Udayana questionnaire are reliable. Based on the results of validity and reliability tests, 23 statements of Udayana's questionnaire are stated valid and reliable and can be used to evaluate the quality of pharmaceutical care at the community health center.
Torsion of ovarian cyst in the third trimester of pregnancy: case report I Nyoman Hariyasa Sanjaya; Cokorda Istri Mirayani Pemayun; Ni Putu Nining Gianni; Made Diah Vendita Sakuntari; Ni Wayan Dewi Purwanti; Ni Luh Made Diah Mas Cahyani Putri; Ni Luh Md Dwi Laxmi Satriani; Ni Komang Anik Pirgantari; Firsta Sesarina Mintariani; Anak Agung Wahyu Putri Agustini; Ketut Widyani Astuti
Indonesian Journal of Perinatology Vol. 3 No. 1 (2022): Available online : 1 June 2022
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v3i1.17

Abstract

Introduction: The entire or partial rotation of the adnexa around its vascular axis or pedicle is known as ovarian torsion. Predisposing factors include short length, unrestricted motion, and a long pedicle. It’s tough to pinpoint the exact cause. Dermoid and serous cyst adenomas are the most common. The complete torsion blocks the venous and lymphatic systems, resulting in stasis, venous congestion, bleeding, and necrosis. The cyst becomes irritable and may explode. A soft cystic mass separate from the uterus can be seen on examination of the affected person, who usually complains of abrupt severe discomfort in the stomach and pelvis. At some time during pregnancy, the risk of ovarian torsion increases by a factor of five. The incidence rate is five per 10,000 pregnancies. Torsion of ovarian tumors was more common among women in their reproductive years. The majority of the instances were seen in pregnant women (22.7%) rather than non-pregnant women (6.1%). Case Description: In this case, we report a 27-year-old primigravida with 36 weeks and 5 days of pregnancy. She presented to the hospital with acute pain abdomen in the lower right (lumbar). She has a history of pregnancy control at a private clinic and there are no abnormalities in her pregnancy. She was hospitalized at 35 weeks 3 days of pregnancy due to the same complaint and has collaborated with the surgeon. No abnormalities were found on the abdominal ultrasound and urology at that time. The baby was born at 36 weeks 6 days of gestation by cesarean section, a twisted ovarian cyst was found on the right ovary, a dextra salpingectomy was performed for oophorectomy and an appendicectomy was also performed at the same time in collaboration with the surgeon. A healthy baby with a weight of 2300 grams and full of breastfeeding. Conclusion: This example demonstrates the problem of manufacturing desirable excellent radiological ultrasound imaging of the pelvic organs in late pregnancy. ultrasound exam in early pregnancy has to also be geared toward the cervix and adnexa which ends up in early analysis and management of ovarian hundreds, thereby fending off future emergency conditions and possible preterm transport.
Twin reversed arterial perfusion syndrome (TRAP or acardiac twin) in pregnancy: a case report I Nyoman Hariyasa Sanjaya; Cokorda Istri Mirayani Pemayun; Ni Luh Made Diah Mas Cahyani Putri; Ni Wayan Dewi Purwanti; Made Diah Vendita Sakuntari; Ni Putu Nining Gianni; Ni Komang Anik Pirgantari; Ni Luh Md Dwi Laxmi Satriani; Firsta Sesarina Mintariani; Anak Agung Wahyu Putri Agustini; Ketut Widyani Astuti
Indonesian Journal of Perinatology Vol. 3 No. 1 (2022): Available online : 1 June 2022
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v3i1.18

Abstract

Introduction: A type of pregnancy that occurs in monochorionic twin pregnancies which results in the coexistence of normal "pump" twins and cardiac twins is called Twin Reverse Arterial Perfusion Syndrome (TRAP). The low oxygen pressure going to the baby causes many unique changes in the twins' physiology. These changes can lead to high prenatal mortality. Case Presentation: We present the case of a 25-year-old woman, primigravida, whose obstetrician referred to Kasih Medika Bali with suspicion of a large placenta. However, upon arrival at 35 weeks and 2 days of gestation, an ultrasound showed a twin pregnancy with suspicion of a TRAP pregnancy. Then, a baby girl was born at Payangan Hospital, Gianyar, Bali by Sectio Caesarea with a birth weight of 3155 grams, an Apgar score of 6-8-9, and a placental weight of 815 grams. The results of the examination of the second fetus that did not develop, weighing 1,705 grams in the placenta did not have an attached umbilical cord. The doctor's suspicions about the TRAP pregnancy were indeed true according to the conditions at the time of the twins' birth. The doctor found 1 healthy baby and 1 other like mass with a size large enough on ultrasound at 35 weeks 2 days of gestation. Conclusion: The incidence of pregnancy like this is very rare and needs further study in order to detect early abnormalities that occur in pregnancy. Thus, we can be aware of the risks for both mother and fetus and even treat them early. Couples can be counseled optimistically that the recurrence rate of TRAP syndrome tends to be low so that they can better plan future pregnancies in all aspects.
Planned home birth in low-risk pregnancies Made Diah Vendita Sakuntari; I Nyoman Hariyasa Sanjaya; Cokorda Istri Mirayani Pemayun; Ni Wayan Dewi Purwanti; Ni Putu Nining Gianni; Ni Luh Made Diah Mas Cahyani Putri; Ni Komang Anik Pirgantari; Ni Luh Md Dwi Laxmi Satriani; Firsta Sesarina Mintariani; Anak Agung Wahyu Putri Agustini; Ketut Widyani Astuti
Indonesian Journal of Perinatology Vol. 3 No. 1 (2022): Available online : 1 June 2022
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v3i1.19

Abstract

Introduction: Planned home births are often a safe option for low-risk pregnancies, according to prior studies. This study aims to ascertain the characteristics of planned home deliveries with skilled medical staff in low-risk pregnancies as well as the outcomes on mother and infant health in Denpasar, Bali. Methods:  The planned home births from 2010 to 2019 were examined in this study using a retrospective descriptive design. The study included all intended home deliveries, including those that required hospital transfers owing to difficulties. As many as 168 planned home births with private doctor assistance made up the study’s sample. Sociodemographic and clinical variables were both examined in this analysis. Results: The mean age of the sample in this study was 32 years.  The findings indicate that women planning a home delivery with a licensed doctor in low-risk pregnancies have a better likelihood of spontaneous vaginal birth and favorable outcomes for maternal health. Additionally, there is a reduced likelihood of hospital transfer (10%). Furthermore, evidence demonstrates that planned home births are typically linked to fetal wellbeing. Conclusion:  The majority of women gave birth between 38 and 40 weeks gestation. The majority of samples were deliveries were normal vaginal births. The main reasons for transfer were due to the arrested cervical dilation or the arrested progress of the fetal head.
Doula Support in The Success of a Normal Delivery I Nyoman Hariyasa Sanjaya; Cokorda Istri Mirayani Pemayun; Made Diah Vendita Sakuntari; Ni Wayan Dewi Purwanti; Ni Putu Nining Gianni; Ni Luh Made Diah Mas Cahyani Putri; Ni Komang Anik Pirgantari; Ni Luh Md Dwi Laxmi Satriani; Firsta Sesarina Mintariani; Anak Agung Wahyu Putri Agustini; Ketut Widyani Astuti
Indonesian Journal of Perinatology Vol. 2 No. 2 (2021): Available online : 1 December 2021
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.72 KB) | DOI: 10.51559/inajperinatol.v2i2.13

Abstract

Introduction: Many mothers who give birth are less interested in giving birth normally because of the intense labor pain. Actually it can be overcome by doula assistance. The doula's presence provides emotional support during the preparation for childbirth, and the doula provides physical support by accompanying to overcome hunger, thirst, and pain. The aim of this study was to determine the effect of doulas assistance on the success of delivery. Methods: This study is a descriptive observational study with a cross-sectional design conducted at a private hospital in Bali in the period January 2020 to January 2021. The inclusion criteria in this study were all pregnant women with gestational age 34 to 40 weeks who were willing to undergo the study. While the exclusion criteria in this study were pregnant women who experienced complications during childbirth and pregnant women with incomplete clinical and demographic data. All of the data was analyzed descriptively by using SPSS 25 and was presented by frequency. Result: This study managed to collect as many as 100 pregnant women who will give birth with the help of a doula. It was found that as many as 60 people (60%) gave birth vaginally. Then followed by 31 people (31%) who underwent a Cesarean section with the help of a doula. There were also 5 people (5%) and 4 people (4%) who underwent epidural delivery and vacuum extraction with the help of a doula. Conclusion: Doula assistance during labor can increase the confidence of the mother who will give birth and support the success of normal delivery.
EFEKTIVITAS PENGGUNAAN MINYAK AROMATERAPI LAVENDER (Lavandula angustifolia) DALAM PENURUNAN TEKANAN DARAH PADA HIPERTENSI Putu Ita Purnama Dewi; Ketut Widyani Astuti
JOURNAL SCIENTIFIC OF MANDALIKA (JSM) e-ISSN 2745-5955 | p-ISSN 2809-0543 Vol. 3 No. 11 (2022): November
Publisher : Institut Penelitian dan Pengembangan Mandalika Indonesia (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/10.36312/JSM

Abstract

Hipertensi merupakan peningkatan tekanan darah baik diastolik maupun sistolik secara hilang timbul atau menetap. Hipertensi dapat terjadi secara esensial (primer atau idiopatik) dimana faktor penyebabnya tidak dapat diidentifikasi, atau secara sekunder, akibat dari penyakit tertentu yang diderita. Salah satu terapi yang dapat menurunkan hipertensi yaitu aromaterapi. Aromaterapi merupakan salah satu pengobatan komplementer yang menggunakan minyak esensial sebagai agen terapi utama. Salah satu tanaman yang dapat dijadikan sebagai aromaterapi adalah bunga lavender (Lavandula angustifolia). Aromaterapi lavender merupakan suatu cara perawatan tubuh atau penyembuhan dengan menggunakan minyak esensial. Aromaterapi lavender bekerja dengan mempengaruhi fisik dan juga emosi. Tujuan dari review artikel ini untuk mengetahui penggunaan aroma terapi lavender (Lavandula angustifolia) pada penurunan hipertensi. Metode yang digunakan dalam pembuatan artikel review ini yaitu studi pustaka. Pustaka yang digunakan merupakan jurnal nasional maupun internasional yang membahas mengenai penggunaan aroma terapi lavender pada hipertensi yang diterbitkan secara online dari berbagai situs seperti Google Scholar, Science Direct, Researchgate, Pubmed, dan Springerlink dengan menggunakan kata kunci aromaterapi lavender dan hipertensi. Kesimpulan pada review artikel ini Berdasarkan hasil analisis beberapa artikel bahwa penggunaan aromaterapi lavender sebagai relaksasi efektif menurunkan tekanan darah atau hipertensi secara signifikan.
Adenomyosis- surgical treatment for women’s infertility Laparotomy with Osada technique I Nyoman Hariyasa Sanjaya; Cokorda Istri Mirayani Pemayun; Ni Komang Anik Pirgantari; Made Diah Vendita Sakuntari; Ni Wayan Dewi Purwanti; Ni Putu Nining Gianni; Ni Luh Made Diah Mas Cahyani Putri; Ni Luh Md Dwi Laxmi Satriani; Firsta Sesarina Mintariani; Anak Agung Wahyu Putri Agustini; Ketut Widyani Astuti
Indonesian Journal of Perinatology Vol. 3 No. 2 (2022): (Available online: 1 December 2022)
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v3i2.25

Abstract

Introduction: Adenomyosis became challenging in the gynecological field and healthcare economic aspect. The prevalence of adenomyosis is widely ranged in different countries. Infertility is one of the frightening complications. Thus a radical adenomyosis tissue removal method using the triple-flap (the Osada technique) could be done. Using this technique the adenomyosis tissue can be removed as much as possible while maintaining normal uterine function. Thus, in this case, report, we performed a woman diagnosed with adenomyosis underwent the surgery with Osada technique. Case description: A 30-year-old woman went to the medical care of Kasih Medika. She has been married for 4,5 years and did not have any children. She had a history of abdominal pain every menstruation, and it has persisted since 2 months ago even though not on the menstrual schedule. Transvaginal sonographic examination revealed a diffusely enlarged uterus and thickening of the uterine wall. A laparotomy is performed using the Osada technique (triple flap. After that, around 1 month after surgery, the patient will undergo an ultrasound examination and the patient will undergo the GnRH agonist therapy (Tapros) 3 times. Conclusion: Adenomyosis is one of the challenging diseases. Adequate treatment must be done to minimalize the infertile probability Laparotomy with the Osada technique could be done. Infertility examination in both couples also must be done. Undergoing the GnRH agonist therapy also can give a better result for the patient.
The Incidence of Vaginal Deliveries in Obese Mothers at Prof Dr. I.G.N.G Ngoerah Hospital In 2022 I Nyoman Hariyasa Sanjaya; Cokorda Istri Mirayani Pemayun; Ni Wayan Dewi Purwanti; Made Diah Vendita Sakuntari; Ni Putu Nining Gianni; Ni Luh Made Diah Mas Cahyani Putri; Ni Luh Md Dwi Laxmi Satriani; Firsta Sesarina Mintariani; Ketut Widyani Astuti
Indonesian Journal of Perinatology Vol. 4 No. 1 (2023): (Available online: 1 June 2023)
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v4i1.30

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Introduction: One of the risk factors seen most frequently in obstetric practice is maternal obesity. Women who were overweight or obese made up more than half of all female fatalities due to direct or indirect causes. Obesity increases the chance that the mother will experience obstetric problems during pregnancy, labour, and delivery, making fetal assessment more technically difficult. Methods: This study uses quantitative descriptive univariate analysis. The type of data is secondary data taken from the birth register. This study examines women who gave birth in 2022 and were identified as belonging to the obesity category by Prof. Dr. I. G. N. G. Ngoerah Denpasar General Hospital. Results: At Prof.dr.I.G.N.G Ngoerah Denpasar General Hospital, 21 obese pregnant women will give birth throughout 2022. Of the 21 people, 81% give birth by emergency C-section, 4,8% by elective C-section, and 14,2% give birth vaginally. Obese pregnant women have a higher risk of needing a cesarean section. Patients with obese class III had a significantly higher risk of infant morbidity than those with a normal BMI, according to their findings. Conclusions: Obese pregnant women are at increased risk of having a cesarean section. Therefore, health workers must provide knowledge to pre-pregnant or pre-marital women to maintain their BMI so they do not become obese during pregnancy. Thus, morbidity and mortality rates can also be reduced.
Activity of Bangle Rhizome Extract (zingiber cassumunar roxb.) Inhibits the Growth of Trichophyton rubrum and Trichophyton mentagrophytes Inderiati, Dewi; Widhyasih, Retno Martini; Aryadnyani, Ni Putu; Warditianin, Ni Kadek; Astuti, Ketut Widyani
SANITAS: Jurnal Teknologi dan Seni Kesehatan Vol 14 No 2 (2023): SANITAS Volume 14 Nomor 2 Tahun 2023
Publisher : Politeknik Kesehatan Kemenkes Jakarta II

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36525/sanitas.2023.475

Abstract

Bangle rhizome extract (zingiber purpureum roxb.) is a herbal plant that is widely consumed in Indonesia. Bangle rhizome extract (zingiber purpureum roxb.) has broad medical properties such as diuretic, anti-hypertension, brochodilator, immunomodulator, analgesic, anti-inflammatory, anti-oxidant, anti-tumor, anti-diabetic, anti-microbial and anti-fungal. The aim of this research was to determine the yield results of extracts using the solvents Aquadest, Aceton, Ethanol 70%, Ethanol 96% and Methanol. And to find out the results of phytochemical screening tests and active ingredient content using GCMS. The stages of this research include the extraction process, phytochemical screening test and GCMS. The results of research on the yield of Bangle rhizome extract with the five solvents obtained the largest yield, namely with distilled water, 7.2 percent. Based on the phytochemical screening test, Bangle rhizome extract was positive for containing secondary metabolites such as tannins, alkaloids, triterpenoids, steroids and saponins. The lowest MIC results for Bangle extract were in Aquadest solvent at 6.25 mg/mL with a value of 0.049 mg/mL and continued in 70% Ethanol solvent with a value of 3.125 mg/mL in the fungus Trichophyton rubrum and in the fungus Trichophyton mentagrophytes with an MIC value of 3.125 mg/mL. while the highest MIC value was obtained in the solvent acetone, Ethanol 96%, Methanol with a value of 0.049 ml/ML for both fungi.
Co-Authors Anak Agung Gede Rai Yadnya Putra Anak Agung Wahyu Putri Agustini Anak Agung Wahyu Putri Agustini Anak Agung Wahyu Putri Agustini Arifani Siswidiasari Aryadnyani, Ni Putu Aryani, Kadek Indra Cokorda Istri Mirayani Pemayun Cokorda Istri Mirayani Pemayun Cokorda Istri Mirayani Pemayun D. A. Satriawati Damayanti, Dewa Ayu Trisna Dewa Ayu Satriawati Dewi Inderiati Dewi LPMK Dewi, Ni Pande Kadek Sinta Firsta Sesarina Mintariani Firsta Sesarina Mintariani Firsta Sesarina Mintariani Fitri NPE G. M. D. Putra I Gde Pande Aninditha Putra Wicaksana I Gusti Made Aman I Gusti Ngurah Agung Dewantara Putra I Gusti Ngurah Jemmy Anton Prasetia I Made Agus Gelgel Wirasuta I Nyoman Hariyasa Sanjaya I Nyoman Hariyasa Sanjaya I Wayan Martadi Santika I Wayan Putu Sutirta Yasa I. N. K. Widjaja Ida Bagus Made Oka L.P.M.K. Dewi Lestari, Ni Wayan Febriari Liyani, Kadek Yunita Luh Putu Febryana L Luh Putu Febryana Larasanty Luh Putu Febryana Larasanty M. D. Abimanyu M. R Sutharini Made Diah Vendita Sakuntari Made Diah Vendita Sakuntari Made Diah Vendita Sakuntari Made Krisna Adi Jaya N. K. Cahyaningsih N. K. M. Ariani, N. L. P. V. Paramita N. P. A. D. Wijayanti N. P. A. D. Wijayanti N. W. M Lina N.M.P. Susanti Ni Komang Anik Pirgantari Ni Komang Anik Pirgantari Ni Komang Anik Pirgantari Ni Komang Cahyaningsih Ni Luh Gede Lisniawati Ni Luh Made Diah Mas Cahyani Putri Ni Luh Made Diah Mas Cahyani Putri Ni Luh Made Diah Mas Cahyani Putri Ni Luh Md Dwi Laxmi Satriani Ni Luh Md Dwi Laxmi Satriani Ni Luh Md Dwi Laxmi Satriani Ni Nyoman Fabby Sukarmini Ni Nyoman Mahatriny, Ni Nyoman Ni Nyoman Wiwik S Ni Nyoman Wiwik S. Ni Putu Ariantari Ni Putu Ayu Dewi Wijayanti Ni Putu Linda Laksmiani Ni Putu Nining Gianni Ni Putu Nining Gianni Ni Putu Nining Gianni Ni Putu Sanggra Payani, Ni Putu Ni Wayan Dewi Purwanti Ni Wayan Dewi Purwanti Ni Wayan Dewi Purwanti Nirmalayanthi, Putu Ayuning Dinda Pande Ketut Suwanti Devi, Pande Ketut Putu Ita Purnama Dewi R. A. I. K. Maharani Rasmaya Niruri Rini Noviyani Sagun Chandra Yowani Santri Yulita Santri Yulita, Santri Siwananda, I Dewa Made T. Maharani Warditianin, Ni Kadek Widhyasih, Retno Martini Wiwik S, Ni Nyoman Yeyet C. Sumirtapura Yeyet C. Sumirtapura Yeyet C. Sumirtapura