Article Per Year (5 Year)
p-Index From 2021 - 2026
3.457
P-Index
This Author published in this journals
All Journal Pharmasipha Medical Sains : Jurnal Ilmiah Kefarmasian Indonesian Journal on Medical Science (IJMS) Indonesian Journal of Medical Chemistry and Bioinformatics Proceeding of International Conference Health, Science And Technology (ICOHETECH) JURNAL FARMASI DAN KESEHATAN INDONESIA Parapemikir Jurnal Ilmiah Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Sains dan Kesehatan Jurnal Ilmu Kesehatan Masyarakat (The Public Health Science Journal) Jurnal Ilmiah Farmasi Indonesia (JIFIN)
Veranita, Weri
Fakultas Farmasi, Universitas Pancasila, Jalan Raya Lenteng Agung Srengseng Sawah, Jakarta
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Physics Public Health

Published : 17 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 17 Documents
Search

 1   2 
Sediaan Granula Effervescent Moracenta Drink Sebagai Suplemen Makanan dalam Upaya Pencegahan Stunting Rizqi Pratiwi, Retno Inten; Nusanty, Oci Etri; Veranita, Weri
Jurnal Ilmu Kesehatan Masyarakat Vol. 14 No. 02 (2025): Jurnal Ilmu Kesehatan Masyarakat
Publisher : UIMA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jikm.v14i02.3813

Abstract

Stunting terjadi akibat dari praktik pemberian makan anak yang kurang tepat Pemberian Makanan Tambahan (PMT) merupakan strategi penanganan masalah gizi. Centella asiatica atau tanaman pegagan Pegagan mengandung makronutrien, mineral dan phytonutrrien yang memiliki efek antioksidan juga berpengaruh pada pertumbuhan, peningkatan panjang tubuh dan kesehatan otak. Tujuan penelitian ini untuk pengembangan Granula Effervescent Moracenta Drink menjadi alternatif pilihan minuman kaya gizi Penelitian ini menggunakan eksperimental (Experiment Research).Penelitian eksperimental merupakan kegiatan percobaan yang bertujuan dalam pengembangan Granula Effervescent Moracenta Drink menjadi alternatif pilihan minuman kaya gizi. Hasil rendaman ekstrak diperoleh persentase untuk ekstrak daun kelor sebanyak 11,252% dan daun pegagan 12,466%. Pengujian bebas etanol, timbal dan logam cadmium dari hasil uji bahwa ekstrak bebas dari etanol dan logam. Skrining fitokimia menunjukkan bahwa Daun Kelor (Moringa oleifera L.) dan pegagan positif mengandung alkaloid, flavonoid, saponin, tanon steroid dan tertenoid.
Analysis of Differentially Expressed Genes (DEG) and Upstream Regulator Proteins Indicates That Inhibition of Transforming Growth Factor Beta 1 (TGFB1) is A Potential Target for Acne Inversa Veranita, Weri; Fauziah, Siva; Nurbaya, Siti
Indonesian Journal of Medical Chemistry and Bioinformatics Vol. 3, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Acne inversa (AI) is a chronic inflammatory skin disease characterized by painful nodules, abscesses, and scarring, primarily in intertriginous areas. This study aims to identify potential therapeutic targets for managing acne inversa based on the analysis of differentially expressed genes (DEG). The expression targets of these genes were then validated for their potential as biomarkers, and upstream regulator proteins (URPs) were identified from the resulting DEG. DEG analysis on the GEO dataset GSE122592 (acne inversa vs. healthy donor skin) revealed five DEG that can serve as biomarkers for acne inversa, with a sensitivity and specificity of (100%). These DEG—IL10, GZMB, FASLG, PRF1, and HLA-DPB10—are genes associated with autoimmune thyroiditis (AIT). AIT has previously been significantly linked to acne vulgaris. URP analysis indicates that inhibition of Transforming Growth Factor Beta 1 (TGFB1) is a therapeutic target that could be used to downregulate these five DEGs, returning their expression to healthy skin levels.
Analysis of Differentially Expressed Genes (DEGS) Related to Interleukin-17 Signaling for Biomarker Identification and Therapeutic Targets in Atopic Eczema Fauziah, Siva; Veranita, Weri; Nurbaya, Siti; Sari, Puji
Indonesian Journal of Medical Chemistry and Bioinformatics Vol. 3, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Atopic eczema, also known as atopic dermatitis, is a chronic inflammatory skin condition characterized by itchy, red, and swollen skin. It is often associated with other atopic diseases such as asthma and hay fever. Interleukin-17 (IL-17), a pro-inflammatory cytokine, plays a crucial role in various inflammatory and autoimmune conditions, including atopic eczema. This study aims to identify potential therapeutic targets for managing atopic eczema based on the analysis of differentially expressed genes (DEGs). The expression of these gene targets was subsequently validated for their potential as biomarkers. Additionally, upstream regulator protein (URP) searches for the resulting DEGs were conducted. DEG analysis of the Gene Expression Omnibus (GEO) dataset, GSE6012 (atopic eczema vs. healthy donor skin), revealed that genes related to IL-17 signaling—FOSL1, MMP1, DEFB4B, S100A7, S100A8, and S100A9—can serve as biomarkers for atopic eczema with sensitivity and specificity values of 1.000. URP analysis suggested that inhibition of IL1A and NOG, as well as TGFB1 activity, are potential therapeutic targets to downregulate these six DEGs, thereby restoring their expression to the levels observed in healthy skin.
Evaluasi Potensi Toksisitas Seluler Ekstrak Daun Benger (Lagerstroemia ovalifolia Teijsm. & Binn) menggunakan Uji Microtetrazolium (MTT) pada Kultur Sel RAW 264.7 veranita, weri
Parapemikir : Jurnal Ilmiah Farmasi Vol 14, No 3 (2025): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v14i3.9122

Abstract

Tanaman Daun Benger (Lagerstroemia ovalifolia Teijsm. Binn) merupakan salah satu tanaman lokal yang secara empiris digunakan dalam pengobatan tradisional. Namun saat ini belum tersedia data ilmiah yang memadai terkait aspek keamanannya, sehingga pemanfaatan lebih lanjut dalam pengembangan obat herbal masih terbatas. Penelitian ini bertujuan untuk menganalisis profil keamanan ekstrak etanol 70% daun  benger secara in vitro sebagai dasar pengembangan produk herbal. Ekstrak benger diperoleh melalui esktraksi dengan metode perkolasi dan diuji toksisitas selulernya menggunakan metode MTT assay pada kultur sel RAW 264.7. Hasil uji menunjukkan bahwa rentan konsentrasi 25-100 µg/mL. Ekstrak daun benger tidak menunjukkan efek toksisitas terhadap sel RAW 264.7, sedangkan pada konsentrasi lebih tinggi (hingga 200 µg/mL) mulai menunjukkan kategori toksisitas sedang. Studi ini memberikan informasi awal menggenai profil keamanan ekstrak daun Benger, dan dapat menjadi landasan penelitian selanjutnya terkait pengembangan obat herbal yang lebih aman dan efektif.Kata kunci— Lagerstroemia ovalifolia Teijsm. Binn, MTT assay,RAW 264,7, Sitotoksisitas
Tingkat Pengetahuan Obat Bebas dan Obat Bebas Terbatas untuk Swamedikasi pada Masyarakat Perum Cengkong, Karawang: Knowledge Level of Over-the-Counter and Limited Over-the-Counter Drugs for Self-Medication Among the Community of Perum Cengkong, Karawang Mariyana, Tyssa; Veranita, Weri; Fajariyani, Ayu; Herawan, Annisa Aliffiah
Jurnal Ilmiah Farmasi Indonesia (JIFIN) Vol 2 No 01 (2024): JIFIN: Jurnal Ilmiah Farmasi Indonesia
Publisher : UIMA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jifin.v2i01.3126

Abstract

Knowledge of the correct medicine can certainly be said to be something important. With the right knowledge, people will be able to get the maximum benefit from the drug and can minimize all unwanted things that can occur due to the use of the drug. This study used purposive sampling and simple random sampling methods on certain variables. Data collection methods in this study include interviews and observations to obtain information about community knowledge. This study only aims to describe the object studied aims to determine the level of knowledge of the use of over-the-counter drugs and limited over-the-counter drugs in the public about knowledge of the use of over-the-counter drugs and limited over-the-counter drugs with the kiuisioner method found with good category results as many as 41 respondents (19%), for the sufficient category as many as 86 respondents (40%) and for the less category as many as 88 respondents (41%). This shows some correspondents who do not know about recognizing the signs of drug classes, how to get drugs, drug doses, drug indications, and how to store drugs.
Penetapan Kadar Flavonoid dan Uji Aktivias Antioksidan Ekstrak Etanol Daun Ketapang (Terminalia catappa L.) dengan Metode ABTS: Determination of Flavonoid Levels and Antioxidant Activity Test of Ethanol Etract Ketapang Leaf (Terminalia catappa L.) Using ABTS Method Ningsih, Wahyuni; Septiarini, Anita Dwi; Veranita, Weri
Jurnal Ilmiah Farmasi Indonesia (JIFIN) Vol 1 No 01 (2023): JIFIN: Jurnal Ilmiah Farmasi Indonesia
Publisher : UIMA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jifin.v1i01.2445

Abstract

Ketapang leaves (Terminalia catappa L.) is a plant that contains chemical compounds such as flavonoids, alkaloids, tannins, triterpenoids or steroids, resins, and saponins. This compound has potential as an antioxidant in absorbing and neutralizing free radicals. This study aims to determine the levels of flavonoid compounds, to determine whether the ethanol extract of ketapang leaves has antioxidant activity as expressed by the IC50 value and to determine the antioxidant power of the ethanol extract of ketapang leaves. The extract was prepared by maceration method using 96% ethanol. Determination of flavonoid levels and antioxidant activity was carried out using a UV-Vis spectrophotometer. Antioxidant activity based on the free radical scavenging ability of the compound ABTS was measured at a wavelength of 740 nm at 17 minutes. The results of determining the levels of flavonoids in the ethanol extract of ketapang leaves were 17,710 QE. Antioxidant activity is expressed in the value of 50% Inhibitory Concentration (IC50) with a yield of 23.531 ppm in ethanol extract. Ketapang leaf ethanol extract has a very strong antioxidant activity.
Docking Molekuler Potensi Antiinflamasi Kandungan Senyawa Benger (Lagerstroemia ovalifolia Teijsm. & Binn) Terhadap 5KIR-Cyclooxygenase-2 (COX-2): Molecular Docking of Anti-Inflammatory Potential of Benger (Lagerstroemia Ovalifolia Teijsm. & Binn) Compounds Against 5KIR - Cyclooxygenase-2 (COX-2) Veranita, Weri; Wibowo, Agung Eru; Listyani, Tiara Ajeng
Jurnal Sains dan Kesehatan Vol. 6 No. 5 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i5.2326

Abstract

Content Benger plant extract compounds (Lagerstroemia ovalifolia Teijsm. & Binn.) are reported as a new class of COX-2 enzyme inhibitors. Molecular docking analysis of Benger plant extract compounds (Lagerstroemia ovalifolia Teijsm. & Binn.) against COX-2 enzyme is required to determine the affinity and interaction pattern between the above compounds and COX-2 enzyme. A total of 23 Benger metabolite compounds were evaluated against COX-2 protein structure (PDB: 5KIR) using Molegro Virtual Docker (MVD) software. The docking results showed that three compounds, namely Kaempferol-3-O-acetyl-glucoside isomer, Acacetin malonylgalactoside, and Kaempferol-3-Oa-L-rhamnoside, had a lower rerank score (more negative) compared to the ligand (RCX_601), indicating potential as COX-2 inhibitors that affect inflammation regulation in silico. In addition, in silico ADMET analysis using pkCSM showed that the three compounds were classified as non-toxic according to BPOM Regulation no. 10 of 2022. Keywords:          Lagerstroemia ovalifolia , Cyclooxygenase-2, Molegro Virtual Docker, 5KIR   Abstrak Senyawa ekstrak tanaman Benger (Lagerstroemia ovalifolia Teijsm. & Binn.)  dilaporkan sebagai kelas baru inhibitor enzim COX-2. Analisis docking molekuler senyawa Senyawa ekstrak tanaman Benger (Lagerstroemia ovalifolia Teijsm. & Binn.)  terhadap enzim     COX-2 diperlukan untuk mengetahui afinitas dan pola interaksi antara senyawa di atas dengan enzim COX-2. Sebanyak 23 senyawa metabolit Benger dievaluasi terhadap struktur protein COX-2 (PDB: 5KIR) menggunakan perangkat lunak Molegro Virtual Docker (MVD). Hasil docking menunjukkan bahwa tiga senyawa, yaitu Kaempferol-3-O-acetyl-glucoside isomer, Acacetin malonylgalactoside, dan Kaempferol-3-Oa-L-rhamnoside, memiliki rerank score yang lebih rendah (lebih negatif) dibandingkan dengan ligan (RCX_601), menunjukkan potensi sebagai inhibitor COX-2 yang mempengaruhi regulasi peradangan secara in silico. Selain itu, analisis ADMET secara in silico menggunakan pkCSM menunjukkan bahwa Kaempferol-3-O-a-L-arabinoside (Juglalin) lebih mudah diabsorpsi oleh usus dibandingkan dengan kedua senyawa lainnya namun ketiga senyawa tersebut diklasifikasikan tidak bersifat toksik. Kata Kunci:         Lagerstroemia ovalifolia , Cyclooxygenase-2, Molegro Virtual Docker, 5KIR
Co-Authors Agung Eru Wibowo Agung Eru Wibowo Ana Yuliana Anik Sulistiyanti Aydi, Danisa Putri Ayu Irma Permatasari, Desy Ayuningsih, Qurotha Chairina, Nurvita Desy Ayu Irma Permatasari Eva Kholifah Fajariyani, Ayu Ferry Effendi Herawan, Annisa Aliffiah Kusumaningtyas Siwi Artini Listyani, Tiara Ajeng Mariyana, Tyssa Musta'in, Musta'in Ningsih, Wahyuni Novalisa Nindhi Soraya Nusanty, Oci Etri Puji Sari Rachmaniar Rachmat Rizqi Pratiwi, Retno Inten Septiarini, Anita Dwi Setianingsih Setianingsih, Setianingsih Siti Nurbaya Siva Fauziah, Siva Tatiana Siska Wardani