Nemay Anggadewi Ndaong
Department Of Anatomy, Physiology, Pharmacology And Biochemistry, Faculty Of Medicine And Veterinary Medicine, Nusa Cendana University, Kupang

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LITERATURE STUDY OF ANTIBIOTIC RESISTANCE ESCHERICHIA COLI IN RIVER BASINS IN INDONESIA Roshelmi Talita Subu Taopan; Novalino Harold Geofrey Kallau; Nemay Anggadewi Ndaong; Fhady Risckhy Loe
Buletin Veteriner Udayana Bul. Vet. Udayana. June 2026 Vol. 18 No. 3
Publisher : Fakultas Kedokteran Hewan Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/bulvet.2026.v18.i03.p01

Abstract

Escherichia coli (E. coli) is an important indicator of faecal contamination in aquatic environments and has been increasingly reported as a reservoir of antibiotic resistance in river ecosystems. This study aimed to review the prevalence and antibiotic resistance patterns of E. coli isolated from river basins in Indonesia through a literature review approach. Scientific articles published in national journals between 2014 and 2024 were collected and analysed descriptively. The results showed that the prevalence of E. coli in river water ranged from 68.51% to 100%. High resistance levels were reported against β-lactam antibiotics, particularly ampicillin and amoxicillin (45-82%), followed by tetracycline (37-71%), streptomycin (73.3%), and tobramycin (57%). In addition, multidrug-resistant (MDR) isolates were identified in several studies, with multidrug-resistant (MDR) prevalence reaching approximately 24% in the Citarum River. These findings indicate that river basins in Indonesia may act as reservoirs for antibiotic-resistant E. coli, highlighting the importance of routine environmental monitoring and proper wastewater management to reduce the spread of antimicrobial resistance.
Pengaruh Pemberian Ivermectin Terhadap Perubahan Sel Darah Putih pada Kambing Kacang yang Dipelihara Secara Intensif Christvando Rendi Leba Tagu Bore; Frans Umbu Datta; Nemay Anggadewi Ndaong; Yustinus Oswin Primajuni Wuhan
JURNAL KAJIAN VETERINER Vol 13 No 2 (2025): Jurnal Kajian Veteriner
Publisher : FAKULTAS KEDOKTERAN HEWAN UNIVERSITAS NUSA CENDANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jkv.v13i2.22628

Abstract

This study aims to determine the effect of Ivermectin on the differential picture of white blood cells of pea goats before and after endoparasite treatment in a semi-intensive rearing system. The study used 11 pea goats placed in individual pens with a platform and fed with KGP 709 concentrate. Ivermectin was given at a dose of 2.5 ml/head. Tools used included a microscope, EDTA tube, syringe, centrifuge, glass slide and cover, and dropper pipette. Parameters observed were white blood cell profile and gastrointestinal parasite infection based on faecal examination. Data were analysed using One Way ANOVA and presented descriptively. Faecal examination results showed gastrointestinal parasite infection with dominant species Haemonchus contortus (5, TPG 1-33), Trichuris spp. (3, maximum TPG 11), Strongyloides spp. (4, maximum TPG 61), Eimeria spp. (6, mild to severe infection), and Cystotoma spp. (5). Ivermectin administration significantly affected the percentage of neutrophils, eosinophils and basophils (p0.05), indicating that Ivermectin did not affect all white blood cell types equally. In conclusion, this study showed that pea goats were infected with gastrointestinal parasites with a predominance of Haemonchus contortus, Trichuris spp., Strongyloides spp., Eimeria spp. and Cystotoma spp. Ivermectin administration was shown to affect neutrophils, eosinophils and basophils, reflecting the immune response to parasitic infection.