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POTENCY OF ENHALUS ACOROIDES FROM INDONESIA REGION FOR HALAL PHARMACEUTICAL INDUSTRY Ismarti, Ismarti; Amelia, Fitrah
JURNAL LEMURU Vol 5 No 1 (2023): JURNAL LEMURU: Jurnal Ilmu Perikanan dan Kelautan Indonesia
Publisher : Program Studi Teknologi Hasil Perikanan|Fakultas Pertanian|Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/lemuru.v5i1.2423

Abstract

Currently, the implementation of the Halal assurance system in Indonesia is mandatory. A side from food, pharmaceutical, cosmetics, and medicines must all be halal certified. Natural products, particularly marine-based products, are an alternative choice for the cosmetics and pharmaceutical industry's raw materials. Enhalus acoroides are common along Indonesia's coasts and have the potential to be used as raw materials in halal cosmetics and pharmaceutical products. The purpose of this paper is to examine the potential of E. acoroides samples collected from various locations in Indonesia in terms of bioactive compounds and their applications. Secondary metabolites namely alkaloids, flavonoids, polyphenols, steroids, triterpenes, and tannins have been reported in E. acoroides extract from Indonesia, and they have the potential to be used as antibacterial, antiaging, antiviral, antitumor, and antioxidant in the pharmaceutical and cosmetic industries in Indonesia
Phytochemical Identification and Antioxidant Activity of Sea Cucumber Collagen Extracted by Maceration and Soxhletation Methods Salamah, Nina; Prasasti, Dian; Anwar, Muslih; Ramses, Ramses; Amelia, Fitrah; Ismarti, Ismarti
Majalah Obat Tradisional Vol 31, No 1 (2026)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.105457

Abstract

Free radicals exert numerous detrimental impacts, necessitating the presence of antioxidants to mitigate these adverse consequences. Previous studies have documented the antioxidant activity of sea cucumber from the Holothuroidea family. However, the impact of extraction techniques on the antioxidant activity of sea cucumber extracts has not been well-studied. Thus, this study aims to examine collagen extracts’ antioxidant activity through two distinct processes: Soxhlet extraction and maceration. The extracted samples were concentrated using the freeze-drying method, followed by a phytochemical analysis, functional group identification via FTIR, and an antioxidant activity assessment using the DPPH method. The antioxidant activity is quantified by the IC50 value. The phytochemical analysis showed that the sea cucumber extract had alkaloids, phenolics, and saponins. The FTIR results indicated that the sea cucumber extract contained a functional carbonyl amide group, akin to that of peptide compounds. The IC50 value of sea cucumber extract obtained from maceration (10.558 ± 0.033) was compared to Soxhlet extraction (19.107 ± 0.041) µg/mL. The antioxidant activity of sea cucumber extract obtained from maceration was superior to that derived from the Soxhlet method.